ATM is a cytoplasmic protein in mouse brain required to prevent lysosomal accumulation. (2000)
Barlow, Carrolee, Ribaut-Barassin, Catherine, Zwingman, Theresa A., Pope, Amber J., Brown, Kevin D., Owens, Jennie W., ...
We previously generated a mouse model with a mutation in the murine Atm gene that recapitulates many aspects of the childhood neurodegenerative disease ataxia-telangiectasia. Atm-deficient (Atm-/-)...
Vita.
ATM is a cytoplasmic protein in mouse brain required to prevent lysosomal accumulation
Barlow, Carrolee, Ribaut-Barassin, Catherine, Zwingman, Theresa A., Pope, Amber J., Brown, Kevin D., Owens, Jennie W., ...
We previously generated a mouse model with a mutation in the murine Atm gene that recapitulates many aspects of the childhood neurodegenerative disease ataxia-telangiectasia. Atm-deficient...
pRB plays an essential role in cell cycle arrest induced by DNA damage
Harrington, Elizabeth A., Bruce, Jacqueline L., Harlow, Ed, Dyson, Nicholas
To maintain genome stability, cells with damaged DNA must arrest to allow repair of mutations before replication. Although several key components required to elicit this arrest have been discovered,...
ATM is a cytoplasmic protein in mouse brain required to prevent lysosomal accumulation
Barlow, Carrolee, Ribaut-Barassin, Catherine, Zwingman, Theresa A., Pope, Amber J., Brown, Kevin D., Owens, Jennie W., ...
We previously generated a mouse model with a mutation in the murine Atm gene that recapitulates many aspects of the childhood neurodegenerative disease ataxia-telangiectasia. Atm-deficient...
pRB plays an essential role in cell cycle arrest induced by DNA damage
Harrington, Elizabeth A., Bruce, Jacqueline L., Harlow, Ed, Dyson, Nicholas
To maintain genome stability, cells with damaged DNA must arrest to allow repair of mutations before replication. Although several key components required to elicit this arrest have been discovered,...