Fonseca, Luis, Seixas, Elsa, Butcher, Geoffrey, Langhorne, Jean
Abstract Background Investigation of host responses to blood stages of Plasmodium spp, and the immunopathology associated with this phase of the life cycle are often performed on mice infected...
A role for B cells in the development of T cell helper function in a malaria infection in mice
Langhorne, Jean, Cross, Caroline, Seixas, Elsa, Li, Ching, Von Der Weid, Thierry
B cell knockout mice are unable to clear a primary erythrocytic infection of Plasmodium chabaudi chabaudi. However, the early acute infection is controlled to some extent, giving rise to a chronic...
Taylor, Philip R., Seixas, Elsa, Walport, Mark J., Langhorne, Jean, Botto, Marina
We have studied the impact of deficiency of the complement system on the progression and control of the erythrocyte stages of the malarial parasite Plasmodium chabaudi chabaudi. C1q-deficient mice...
A role for B cells in the development of T cell helper function in a malaria infection in mice
Langhorne, Jean, Cross, Caroline, Seixas, Elsa, Li, Ching, Von Der Weid, Thierry
B cell knockout mice are unable to clear a primary erythrocytic infection of Plasmodium chabaudi chabaudi. However, the early acute infection is controlled to some extent, giving rise to a chronic...
Taylor, Philip R., Seixas, Elsa, Walport, Mark J., Langhorne, Jean, Botto, Marina
We have studied the impact of deficiency of the complement system on the progression and control of the erythrocyte stages of the malarial parasite Plasmodium chabaudi chabaudi. C1q-deficient mice...
Heme oxygenase-1 affords protection against noncerebral forms of severe malaria
Seixas, Elsa, Gozzelino, Raffaella, Chora, Ângelo, Ferreira, Ana, Silva, Gabriela, Larsen, Rasmus, ...
Infection by Plasmodium, the causative agent of malaria, is associated with hemolysis and therefore with release of hemoglobin from RBC. Under inflammatory conditions, cell-free hemoglobin can be...