O'Hara, Patrick J., Horowitz, Heidi, Eichinger, Greg, Young, Elton T.
The ADR6 gene of Saccharomyces cerevisiae has an open reading frame which could encode a polypeptide of 1314 amino acids. The predicted mRNA encodes a prbtein with homopolymeric stretches of...
Translationsl regulation of expression of the bacteriophage T4 lysozyme gene (1986)
McPheeters, David S., Christensen, Alan, Young, Elton T., Stormo, Gary, Gold, Larry
The bacteriophage T4 lysozyme gene is transcribed at early and late times after infection of E. coli, but the early mRNA is not translated. DNA sequence analysis and mapping of the 5′ ends of the...
Dombek, Kenneth M., Voronkova, Valentina, Raney, Alexa, Young, Elton T.
In Saccharomyces cerevisiae, the protein phosphatase type 1 (PP1)-binding protein Reg1 is required to maintain complete repression of ADH2 expression during growth on glucose. Surprisingly, however,...
Hyperacetylation of chromatin at the ADH2 promoter allows Adr1 to bind in repressed conditions
Verdone, Loredana, Wu, Jiansheng, Riper, Kristen Van, Kacherovsky, Nataly, Vogelauer, Maria, Young, Elton T., ...
We report that in vivo increased acetylation of the repressed Saccharomyces cerevisiae ADH2 promoter chromatin, as obtained by disrupting the genes for the two deacetylases HDA1 and RPD3,...
Tachibana, Christine, Yoo, Jane Y., Tagne, Jean-Basco, Kacherovsky, Nataly, Lee, Tong I., Young, Elton T.
In Saccharomyces cerevisiae, glucose depletion causes a profound alteration in metabolism, mediated in part by global transcriptional changes. Many of the transcription factors that regulate these...
Taguchi, Aileen K. W., Young, Elton T.
The alcohol dehydrogenase II isozyme (enzyme, ADHII; structural gene, ADH2) of the yeast, Saccharomyces cerevisiae, is under stringent carbon catabolite control. This cytoplasmic isozyme exhibits...
Taguchi, Aileen K. W., Young, Elton T.
The alcohol dehydrogenase II (ADH2) gene of the yeast, Saccharomyces cerevisiae, is not transcribed during growth on fermentable carbon sources such as glucose. Growth of yeast cells in a medium...
Voronkova, Valentina, Kacherovsky, Nataly, Tachibana, Christine, Yu, Diana, Young, Elton T.
The transcription factor Adr1 directly activates the expression of genes encoding enzymes in numerous pathways that are upregulated after the exhaustion of glucose in the yeast Saccharomyces...
Infante, Juan J, Dombek, Kenneth M, Rebordinos, Laureana, Cantoral, Jesús M, Young, Elton T
The relative importance of gross chromosomal rearrangements to adaptive evolution has not been precisely defined. The Saccharomyces cerevisiae flor yeast strains offer significant advantages for the...
Dombek, Kenneth M., Voronkova, Valentina, Raney, Alexa, Young, Elton T.
In Saccharomyces cerevisiae, the protein phosphatase type 1 (PP1)-binding protein Reg1 is required to maintain complete repression of ADH2 expression during growth on glucose. Surprisingly, however,...
Hyperacetylation of chromatin at the ADH2 promoter allows Adr1 to bind in repressed conditions
Verdone, Loredana, Wu, Jiansheng, Riper, Kristen Van, Kacherovsky, Nataly, Vogelauer, Maria, Young, Elton T., ...
We report that in vivo increased acetylation of the repressed Saccharomyces cerevisiae ADH2 promoter chromatin, as obtained by disrupting the genes for the two deacetylases HDA1 and RPD3,...
Tachibana, Christine, Yoo, Jane Y., Tagne, Jean-Basco, Kacherovsky, Nataly, Lee, Tong I., Young, Elton T.
In Saccharomyces cerevisiae, glucose depletion causes a profound alteration in metabolism, mediated in part by global transcriptional changes. Many of the transcription factors that regulate these...
Taguchi, Aileen K. W., Young, Elton T.
The alcohol dehydrogenase II isozyme (enzyme, ADHII; structural gene, ADH2) of the yeast, Saccharomyces cerevisiae, is under stringent carbon catabolite control. This cytoplasmic isozyme exhibits...
Taguchi, Aileen K. W., Young, Elton T.
The alcohol dehydrogenase II (ADH2) gene of the yeast, Saccharomyces cerevisiae, is not transcribed during growth on fermentable carbon sources such as glucose. Growth of yeast cells in a medium...
Voronkova, Valentina, Kacherovsky, Nataly, Tachibana, Christine, Yu, Diana, Young, Elton T.
The transcription factor Adr1 directly activates the expression of genes encoding enzymes in numerous pathways that are upregulated after the exhaustion of glucose in the yeast Saccharomyces...
Infante, Juan J, Dombek, Kenneth M, Rebordinos, Laureana, Cantoral, Jesús M, Young, Elton T
The relative importance of gross chromosomal rearrangements to adaptive evolution has not been precisely defined. The Saccharomyces cerevisiae flor yeast strains offer significant advantages for the...
Cyclic changes in metabolic state during the life of a yeast cell
Tu, Benjamin P., Mohler, Rachel E., Liu, Jessica C., Dombek, Kenneth M., Young, Elton T., Synovec, Robert E., ...
Budding yeast undergo robust oscillations in oxygen consumption during continuous growth in a nutrient-limited environment. Using liquid chromatography-mass spectrometry and comprehensive 2D gas...
Young, Elton T., Tachibana, Christine, Chang, Hsin-Wen Ella, Dombek, Kenneth M., Arms, Erin M., Biddick, Rhiannon
The transcription factor Adr1 activates numerous genes in nonfermentable carbon source metabolism. An unknown mechanism prevents Adr1 from stably binding to the promoters of these genes in...
Snf1 Controls the Activity of Adr1 Through Dephosphorylation of Ser230
Ratnakumar, Sooraj, Kacherovsky, Nataly, Arms, Erin, Young, Elton T.
The transcription factors Adr1 and Cat8 act in concert to regulate the expression of numerous yeast genes after the diauxic shift. Their activities are regulated by Snf1, the yeast homolog of the...