Functional comparison of mouse CIRE/mouse DC-SIGN and human DC-SIGN (2006)
Caminschi, Irina, Corbett, Alexandra J, Zahra, Corina, Lahoud, Mireille, Lucas, Karen M, Sofi, Mariam, ...
CIRE/mDC-SIGN is a C-type lectin we originally identified as a molecule differentially expressed by mouse dendritic cell (DC) populations. Immunostaining with a CIRE/mDC-SIGN-specific mAb revealed...
Functional comparison of mouse CIRE/mouse DC-SIGN and human DC-SIGN (2006)
Caminschi, Irina, Corbett, Alexandra J., Zahra, Corina, Lahoud, Mireille, Lucas, Karen M., Sofi, Mariam, ...
CIRE/mDC-SIGN is a C-type lectin we originally identified as a molecule differentially expressed by mouse dendritic cell (DC) populations. Immunostaining with a CIRE/mDC-SIGN-specific mAb revealed...
Genetics of murine leishmaniasis (2005)
Foote, Simon J., Handman, Emanuela
Leishmaniasis encompasses a number of disease syndromes, caused by several species of the digenetic protozoan Leishmania, and is transmitted by sandflies. The mouse model of the disease has been used...
Ng, Ken, Handman, Emanuela, Bacic, Antony
Lipophosphoglycan (LPG) is the major cell surface molecule of promastigotes of all Leishmania species. It is comprised of three domains: a conserved GPI anchor linked to a repeating phosphorylated...
Aebischer, Toni, Morris, Lynn, Handman, Emanuela
It is well established that BALB/c mice can be protected from fatal infection with Leishmania major by prophylactic intravenous (i.v.) immunization with irradiated parasites. Protection is...
Morris, Lynn, Aebischer, Toni, Handman, Emanuela, Kelso, Anne, MacDonald, H. R.
BALB/c mice are highly susceptible to infection with the protozoan parasite Leishmania major and develop a chronic fatal disease. They can, however, be manipulated to resist disease and this has...
Structure and antigenicity of the lipophosphoglycan from Leishmania major amastigotes (1991)
Moody, Susan F., Handman, Emanuela, Bacic, Antony
The lipophosphoglycan (LPG) of the intracellular amastigote form of the protozoan parasite Leishmania major is chemically distinct from the LPG on the surface of the extracellular promastigote form....
Genetic characterization of Leishmania isolates at 37 enzyme loci (1988)
Andrews, Ross H, Handman, Emanuela, Adams, Mark, Baverstock, Peter R, Mitchell, Graham F
Zíková, Alena, Panigrahi, Aswini K., Uboldi, Alessandro D., Dalley, Rachel A., Handman, Emanuela, Stuart, Kenneth
A mitochondrial inner membrane protein, designated MIX, seems to be essential for cell viability. The deletion of both alleles was not possible, and the deletion of a single allele led to a loss of...