Emma E. Hamilton-Williams

Transgenic rescue implicates β2-microglobulin as a diabetes susceptibility gene in nonobese diabetic (NOD) mice

Hamilton-Williams, Emma E., Serreze, David V., Charlton, Brett, Johnson, Ellis A., Marron, Michele P., Müllbacher, Arno, ...

Type 1 diabetes in both humans and nonobese diabetic (NOD) mice results from T-cell-mediated autoimmune destruction of insulin-producing pancreatic β cells. Linkage studies have shown that type 1...

Beta cell MHC class I is a late requirement for diabetes

Hamilton-Williams, Emma E., Palmer, Stephanie E., Charlton, Brett, Slattery, Robyn M.

Type 1 diabetes occurs as a result of an autoimmune attack on the insulin-producing beta cells. Although CD8 T cells have been implicated both early and late in this process, the requirement for...

Transgenic rescue implicates β2-microglobulin as a diabetes susceptibility gene in nonobese diabetic (NOD) mice

Hamilton-Williams, Emma E., Serreze, David V., Charlton, Brett, Johnson, Ellis A., Marron, Michele P., Müllbacher, Arno, ...

Type 1 diabetes in both humans and nonobese diabetic (NOD) mice results from T-cell-mediated autoimmune destruction of insulin-producing pancreatic β cells. Linkage studies have shown that type 1...

Beta cell MHC class I is a late requirement for diabetes

Hamilton-Williams, Emma E., Palmer, Stephanie E., Charlton, Brett, Slattery, Robyn M.

Type 1 diabetes occurs as a result of an autoimmune attack on the insulin-producing beta cells. Although CD8 T cells have been implicated both early and late in this process, the requirement for...

Kidney dendritic cell activation is required for progression of renal disease in a mouse model of glomerular injury

Heymann, Felix, Meyer-Schwesinger, Catherine, Hamilton-Williams, Emma E., Hammerich, Linda, Panzer, Ulf, Kaden, Sylvia, ...

The progression of kidney disease to renal failure correlates with infiltration of mononuclear immune cells into the tubulointerstitium. These infiltrates contain macrophages, DCs, and T cells, but...