Emmanuel Denou

Genome Analysis of Phage JS98 Defines a Fourth Major Subgroup of T4-Like Phages in Escherichia coli▿ †

Zuber, Sophie, Ngom-Bru, Catherine, Barretto, Caroline, Bruttin, Anne, Brüssow, Harald, Denou, Emmanuel

Numerous T4-like Escherichia coli phages were isolated from human stool and environmental wastewater samples in Bangladesh and Switzerland. The sequences of the major head gene (g23) revealed that...

Gene Expression of Commensal Lactobacillus johnsonii Strain NCC533 during In Vitro Growth and in the Murine Gut▿

Denou, Emmanuel, Berger, Bernard, Barretto, Caroline, Panoff, Jean-Michel, Arigoni, Fabrizio, Brüssow, Harald

Work with pathogens like Vibrio cholerae has shown major differences between genes expressed in bacteria grown in vitro and in vivo. To explore this subject for commensals, we investigated the...

Identification of Genes Associated with the Long-Gut-Persistence Phenotype of the Probiotic Lactobacillus johnsonii Strain NCC533 Using a Combination of Genomics and Transcriptome Analysis▿ †

Denou, Emmanuel, Pridmore, Raymond David, Berger, Bernard, Panoff, Jean-Michel, Arigoni, Fabrizio, Brüssow, Harald

Lactobacillus johnsonii strains NCC533 and ATCC 33200 (the type strain of this species) differed significantly in gut residence time (12 versus 5 days) after oral feeding to mice. Genes affecting the...

The Role of Prophage for Genome Diversification within a Clonal Lineage of Lactobacillus johnsonii: Characterization of the Defective Prophage LJ771▿ †

Denou, Emmanuel, Pridmore, Raymond David, Ventura, Marco, Pittet, Anne-Cécile, Zwahlen, Marie-Camille, Berger, Bernard, ...

Two independent isolates of the gut commensal Lactobacillus johnsonii were sequenced. These isolates belonged to the same clonal lineage and differed mainly by a 40.8-kb prophage, LJ771, belonging to...