Emmanuelle Godefroy

αvβ3-dependent cross-presentation of matrix metalloproteinase–2 by melanoma cells gives rise to a new tumor antigen

Godefroy, Emmanuelle, Moreau-Aubry, Agnes, Diez, Elisabeth, Dreno, Brigitte, Jotereau, Francine, Guilloux, Yannick

A large array of antigens that are recognized by tumor-specific T cells has been identified and shown to be generated through various processes. We describe a new mechanism underlying T cell...

KBMA Listeria monocytogenes is an effective vector for DC-mediated induction of antitumor immunity

Skoberne, Mojca, Yewdall, Alice, Bahjat, Keith S., Godefroy, Emmanuelle, Lauer, Peter, Lemmens, Edward, ...

Vaccine strategies that utilize human DCs to enhance antitumor immunity have yet to realize their full potential. Approaches that optimally target a spectrum of antigens to DCs are urgently needed....