Enrique Martín-Gayo

CSL–MAML-dependent Notch1 signaling controls T lineage–specific IL-7Rα gene expression in early human thymopoiesis and leukemia

González-García, Sara, García-Peydró, Marina, Martín-Gayo, Enrique, Ballestar, Esteban, Esteller, Manel, Bornstein, Rafael, ...

Notch1 activation is essential for T-lineage specification of lymphomyeloid progenitors seeding the thymus. Progression along the T cell lineage further requires cooperative signaling provided by the...