Two Piwi proteins, Xiwi and Xili, are expressed in the Xenopus female germline (2009)
Wilczynska, Anna, Minshall, Nicola, Armisen, Javier, Miska, Eric A., Standart, Nancy
The Argonaute superfamily is a large family of RNA-binding proteins involved in gene regulation mediated by small noncoding RNA and characterized by the presence of PAZ and PIWI domains. The family...
Eric A. Miska, Ezequiel Alvarez-Saavedra, Allison L. Abbott, Nelson C. Lau, Andrew B. Hellman, Shannon M. McGonagle, ...
MicroRNAs (miRNAs), a large class of short noncoding RNAs found in many plants and animals, often act to post-transcriptionally inhibit gene expression. We report the generation of deletion mutations...
MicroRNA expression profiling of human breast cancer identifies new markers of tumor subtype (2007)
Blenkiron, Cherie, Goldstein, Leonard D, Thorne, Natalie P, Spiteri, Inmaculada, Chin, Suet-Feung, Dunning, Mark J, ...
Abstract Background MicroRNAs (miRNAs), a class of short non-coding RNAs found in many plants and animals, often act post-transcriptionally to inhibit gene expression. Results Here we report the...
A Slicer-independent role for Argonaute 2 in hematopoiesis and the microRNA pathway (2007)
OCarroll, Dónal, Mecklenbrauker, Ingrid, Das, Partha Pratim, Santana, Angela, Koenig, Ulrich, Enright, Anton J., ...
Binding of microRNA (miRNA) to mRNA within the RNA-induced silencing complex (RISC) leads to either translational inhibition or to destruction of the target mRNA. Both of these functions are executed...
miRNAs in cancer: approaches, aetiology, diagnostics and therapy (2007)
Blenkiron, Cherie, Miska, Eric A.
MicroRNAs (miRNAs) are causing tremendous excitement in cancer research. MiRNAs are a large class of short non-coding RNAs that are found in many plants, animals and DNA viruses and often act to...
Caenorhabditis elegansand friends in Los Angeles (2005)
Alvarez-Saavedra, Ezequiel A, Miska, Eric A
Abstract A report on the 15th Biennial International C. elegans Conference, Los Angeles, USA, 25-29 June 2005.
Microarray analysis of microRNA expression in the developing mammalian brain (2004)
Miska, Eric A, Alvarez-Saavedra, Ezequiel, Townsend, Matthew, Yoshii, Akira, Šestan, Nenad, Rakic, Pasko, ...
Abstract Background MicroRNAs are a large new class of tiny regulatory RNAs found in nematodes, plants, insects and mammals. MicroRNAs are thought to act as post-transcriptional modulators of gene...
Differential localization of HDAC4 orchestrates muscle differentiation (2001)
Miska, Eric A., Langley, Emma, Wolf, Daniel, Karlsson, Christina, Pines, Jon, Kouzarides, Tony
The class II histone deacetylases HDAC4 and HDAC5 interact specifically with the myogenic MEF2 transcription factor and repress its activity. Here we show that HDAC4 is cytoplasmic during myoblast...
Huang, Eric Y., Zhang, Jinsong, Miska, Eric A., Guenther, Matthew G., Kouzarides, Tony, Lazar, Mitchell A.
Differential localization of HDAC4 orchestrates muscle differentiation
Miska, Eric A., Langley, Emma, Wolf, Daniel, Karlsson, Christina, Pines, Jon, Kouzarides, Tony
The class II histone deacetylases HDAC4 and HDAC5 interact specifically with the myogenic MEF2 transcription factor and repress its activity. Here we show that HDAC4 is cytoplasmic during myoblast...
Huang, Eric Y., Zhang, Jinsong, Miska, Eric A., Guenther, Matthew G., Kouzarides, Tony, Lazar, Mitchell A.
Transcriptional repression mediated by corepressors N-CoR and SMRT is a critical function of nuclear hormone receptors, and is dysregulated in human myeloid leukemias. At the present time, these...
Microarray analysis of microRNA expression in the developing mammalian brain
Miska, Eric A, Alvarez-Saavedra, Ezequiel, Townsend, Matthew, Yoshii, Akira, Šestan, Nenad, Rakic, Pasko, ...
A microarray technology suitable for analyzing the expression of microRNAs and of other small RNAs was used to determine the microRNA expression profile during mouse-brain development and observed a...
Caenorhabditis elegans and friends in Los Angeles
Alvarez-Saavedra, Ezequiel A, Miska, Eric A
A report on the 15th Biennial International C. elegans Conference, Los Angeles, USA, 25-29 June 2005.
Differential localization of HDAC4 orchestrates muscle differentiation
Miska, Eric A., Langley, Emma, Wolf, Daniel, Karlsson, Christina, Pines, Jon, Kouzarides, Tony
The class II histone deacetylases HDAC4 and HDAC5 interact specifically with the myogenic MEF2 transcription factor and repress its activity. Here we show that HDAC4 is cytoplasmic during myoblast...
Huang, Eric Y., Zhang, Jinsong, Miska, Eric A., Guenther, Matthew G., Kouzarides, Tony, Lazar, Mitchell A.
Transcriptional repression mediated by corepressors N-CoR and SMRT is a critical function of nuclear hormone receptors, and is dysregulated in human myeloid leukemias. At the present time, these...
Microarray analysis of microRNA expression in the developing mammalian brain
Miska, Eric A, Alvarez-Saavedra, Ezequiel, Townsend, Matthew, Yoshii, Akira, Šestan, Nenad, Rakic, Pasko, ...
A microarray technology suitable for analyzing the expression of microRNAs and of other small RNAs was used to determine the microRNA expression profile during mouse-brain development and observed a...
Caenorhabditis elegans and friends in Los Angeles
Alvarez-Saavedra, Ezequiel A, Miska, Eric A
A report on the 15th Biennial International C. elegans Conference, Los Angeles, USA, 25-29 June 2005.
MicroRNA—implications for cancer
Sassen, Stefanie, Miska, Eric A., Caldas, Carlos
MicroRNAs (miRNAs) are small RNA molecules that regulate gene expression post-transcriptionally. After the discovery of the first miRNA in the roundworm Caenorhabditis elegans, these short regulatory...
Members of the miRNA-200 Family Regulate Olfactory Neurogenesis
Choi, Philip S., Zakhary, Lisa, Choi, Wen-Yee, Caron, Sophie, Alvarez-Saavedra, Ezequiel, Miska, Eric A., ...
MicroRNAs (miRNAs) are highly expressed in vertebrate neural tissues, but the contribution of specific miRNAs to the development and function of different neuronal populations is still largely...
A Slicer-independent role for Argonaute 2 in hematopoiesis and the microRNA pathway
O’Carroll, Dónal, Mecklenbrauker, Ingrid, Das, Partha Pratim, Santana, Angela, Koenig, Ulrich, Enright, Anton J., ...
Binding of microRNA (miRNA) to mRNA within the RNA-induced silencing complex (RISC) leads to either translational inhibition or to destruction of the target mRNA. Both of these functions are executed...
MicroRNA expression profiling of human breast cancer identifies new markers of tumor subtype
Blenkiron, Cherie, Goldstein, Leonard D, Thorne, Natalie P, Spiteri, Inmaculada, Chin, Suet-Feung, Dunning, Mark J, ...
Integrated analysis of miRNA expression and genomic changes in human breast tumors allows the classification of tumor subtypes.
MicroRNA Biogenesis Is Required for Mouse Primordial Germ Cell Development and Spermatogenesis
Hayashi, Katsuhiko, Kaneda, Masahiro, Tang, Fuchou, Hajkova, Petra, Lao, Kaiqin, ...
Most Caenorhabditis elegans microRNAs Are Individually Not Essential for Development or Viability
Miska, Eric A, Alvarez-Saavedra, Ezequiel, Abbott, Allison L, Lau, Nelson C, Hellman, Andrew B, McGonagle, Shannon M, ...
MicroRNAs (miRNAs), a large class of short noncoding RNAs found in many plants and animals, often act to post-transcriptionally inhibit gene expression. We report the generation of deletion mutations...
Two Piwi proteins, Xiwi and Xili, are expressed in the Xenopus female germline
Wilczynska, Anna, Minshall, Nicola, Armisen, Javier, Miska, Eric A., Standart, Nancy
The Argonaute superfamily is a large family of RNA-binding proteins involved in gene regulation mediated by small noncoding RNA and characterized by the presence of PAZ and PIWI domains. The family...