Eric Lander

1 Describing Graphs: a First-Order Approach to (2008)

Graph Canonization, Neil Immerman, Eric Lander

ABSTRACT In this paper we ask the question, \What must be added to rst-order logic plus least- xed point to obtain exactly the polynomial-time properties of unordered graphs? " We consider...

1 Describing Graphs: a First-Order Approach to (2007)

Graph Canonization, Neil Immerman, Eric Lander

ABSTRACT In this paper we ask the question, "What must be added to first-order logic plus least-fixed point to obtain exactly the polynomial-time properties of unordered graphs? "...

Dorsoventral Patterning in Hemichordates: Insights into Early Chordate Evolution (2006)

Christopher J. Lowe, Mark Terasaki, Michael Wu, Robert M. Freeman Jr., Linda Runft, Kristen Kwan, ...

We have compared the dorsoventral development of hemichordates and chordates to deduce the organization of their common ancestor, and hence to identify the evolutionary modifications of the chordate...

Corticosteroid Pharmacogenetics: Association of sequence variants in CRHR1 with improved lung function in asthmatics treated with inhaled corticosteroids (2004)

Tantisira, Kelan G., Lake, Stephen, Silverman, Eric S., Palmer, Lyle J., Lazarus, Ross, Silverman, Edwin K., ...

Corticosteroids mediate a variety of immunological actions and are commonly utilized in the treatment of a wide range of diseases. Unfortunately, therapy with this class of medications is associated...

Corticosteroid pharmacogenetics: association of sequence variants in CRHR1 with improved lung function in asthmatics treated with inhaled corticosteroids (2004)

Tantisira, Kelan G., Lake, Stephen, Silverman, Eric S., Palmer, Lyle J., Lazarus, Ross, Silverman, Edwin K., ...

Corticosteroids mediate a variety of immunological actions and are commonly utilized in the treatment of a wide range of diseases. Unfortunately, therapy with this class of medications is associated...

Corticosteroid Pharmacogenetics: Association of sequence variants in CRHR1 with improved lung function in asthmatics treated with inhaled corticosteroids (2004)

Tantisira, Kelan G., Lake, Stephen, Silverman, Eric S., Palmer, Lyle J., Lazarus, Ross, Silverman, Edwin K., ...

Corticosteroids mediate a variety of immunological actions and are commonly utilized in the treatment of a wide range of diseases. Unfortunately, therapy with this class of medications is associated...

Molecular classification of multiple tumor types (2001)

Yeang, Chen-Hsiang, Ramaswamy, Sridhar, Tamayo, Pablo, Mukherjee, Sayan, Rifkin, Ryan M., Angelo, Michael, ...

Using gene expression data to classify tumor types is a very promising tool in cancer diagnosis. Previous works show several pairs of tumor types can be successfully distinguished by their gene...

Asymptotic Distribution of the Likelihood Ratio Test That a Mixture of Two Binomials is a Single Binomial. (1998)

Chernoff, Herman, Lander, Eric

A problem of interest in genetics is that of testing whether a mixture of two binomial distributions B sub i (k, p) and B sub i (k, 1/2) is simply the pure distribution B sub i (k, 1/2). This problem...

Localization of the EPM1 gene for progressive myoclonus epilepsy on chromosome 21: linkage disequilibrium allows high resolution mapping (1993)

Lehesjokl, Anna-Ellna, Koskiniemi, Marjaleena, Norio, Reljo, Tirrito, Salvatore, Sistonen, Perttl, Lander, Eric, ...

The gene for Progressive myoclonus epilepsy of Unverricht- Lundborg type (EPM1) has previously been mapped by linkage to markers on chromosome 21q22.3. By analyzing crossover events in multiplex...

Genomic mapping by anchoring random clones: a mathematical analysis (1991)

Richard Arratia, Eric Lander, T* Simon Tavar, Michael Waterman

A complete physical map of the DNA of an organism, consisting of overlapping clones spanning the genome, is an extremely useful tool for genomic analysis. Various methods for the construction of such...

Describing Graphs: a First-Order Approach to Graph Canonization (1990)

Graph Canonization, Neil Immerman, Eric Lander

In this paper we ask the question, "What must be added to first-order logic plus least-fixed point to obtain exactly the polynomial-time properties of unordered graphs?" We consider the...

The Genome of M. acetivorans Reveals Extensive Metabolic and Physiological Diversity

Galagan, James E., Nusbaum, Chad, Roy, Alice, Endrizzi, Matthew G., Macdonald, Pendexter, FitzHugh, Will, ...

Methanogenesis, the biological production of methane, plays a pivotal role in the global carbon cycle and contributes significantly to global warming. The majority of methane in nature is derived...

Dorsoventral Patterning in Hemichordates: Insights into Early Chordate Evolution

Lowe, Christopher J, Terasaki, Mark, Wu, Michael, Freeman, Robert M, Runft, Linda, Kwan, Kristen, ...

We have compared the dorsoventral development of hemichordates and chordates to deduce the organization of their common ancestor, and hence to identify the evolutionary modifications of the chordate...

The Genome of M. acetivorans Reveals Extensive Metabolic and Physiological Diversity

Galagan, James E., Nusbaum, Chad, Roy, Alice, Endrizzi, Matthew G., Macdonald, Pendexter, FitzHugh, Will, ...

Methanogenesis, the biological production of methane, plays a pivotal role in the global carbon cycle and contributes significantly to global warming. The majority of methane in nature is derived...

Dorsoventral Patterning in Hemichordates: Insights into Early Chordate Evolution

Lowe, Christopher J, Terasaki, Mark, Wu, Michael, Freeman, Robert M, Runft, Linda, Kwan, Kristen, ...

We have compared the dorsoventral development of hemichordates and chordates to deduce the organization of their common ancestor, and hence to identify the evolutionary modifications of the chordate...