Degradation of Bcl10 Induced by T-Cell Activation Negatively Regulates NF-κB Signaling
Scharschmidt, Erika, Wegener, Elmar, Heissmeyer, Vigo, Rao, Anjana, Krappmann, Daniel
Bcl10 is a critical regulator of NF-κB activity in T and B cells, coupling antigen receptor signaling to NF-κB activation via protein kinase C (PKC). Here we show that PKC or T-cell receptor...
Degradation of Bcl10 Induced by T-Cell Activation Negatively Regulates NF-κB Signaling
Scharschmidt, Erika, Wegener, Elmar, Heissmeyer, Vigo, Rao, Anjana, Krappmann, Daniel
Bcl10 is a critical regulator of NF-κB activity in T and B cells, coupling antigen receptor signaling to NF-κB activation via protein kinase C (PKC). Here we show that PKC or T-cell receptor...