Vanderschaeghe, Dieter, Laroy, Wouter, Sablon, Erwin, Halfon, Philippe, Van Hecke, Annelies, Delanghe, Joris, ...
Liver fibrosis is currently assessed by liver biopsy, a costly and rather cumbersome procedure that is unsuitable for frequent patient monitoring, which drives research into biomarkers for this...
Evaluation of Versant hepatitis C virus genotype assay (LiPA) 2.0 (2008)
Stanley, Mark J, Shieh, Jen, Celis, Linda, Huyck, Els, ...
Hepatitis C virus (HCV) genotyping is a tool used to optimize antiviral treatment regimens. The newly developed Versant HCV genotype assay (LiPA) 2.0 uses sequence information from both the 5'...
Molecular epidemiology of hepatitis C virus subtype 3a in injecting drug users (2006)
Cantaloube, Jean-Francois, Beaucourt, Stephanie, Barbotte, Laetitia, De Gendt, Sija, Goncales, Fernando Lopes, ...
Hepatitis C virus subtype 3a (HCV-3a) originates from Asia and has spread widely among injecting drug users as well as other patient groups in industrialized countries. HCV subtype 3a infection...
Molecular epidemiology of hepatitis C virus subtype 3a in injecting drug users (2006)
Morice, Yoann, Cantaloube, Jean-Francois, Beaucourt, Stephanie, Barbotte, Laetitia, De Gendt, Sija, Lopes Goncales, Fernando, ...
Hepatitis C virus subtype 3a (HCV-3a) originates from Asia and has spread widely among injecting drug users as well as other patient groups in industrialized countries. HCV subtype 3a infection...
Genotypic resistance to lamivudine among hepatitis B virus isolates in Mexico (2006)
Alvarado-Esquivel, Cosme, Conde-González, Carlos Jesús, Juárez-Figueroa, Luis, Ruiz-Maya, Lilia, Aguilar-Benavides, Sergio, ...
Background: Drug resistance of hepatitis B virus (HBV) is an increasing clinical problem. Resistance to lamivudine in HBV isolates in Mexico has been poorly explored. Objectives: To characterize the...
Genotypic resistance to lamivudine among hepatitis B virus isolates in Mexico (2005)
Alvarado-Esquivel, Cosme, Conde-González, Carlos Jesús, Juárez-Figueroa, Luis, Ruiz-Maya, Lilia, Aguilar-Benavides, Sergio, ...
Background: Drug resistance of hepatitis B virus (HBV) is an increasing clinical problem. Resistance to lamivudine in HBV isolates in Mexico has been poorly explored. Objectives: To characterize the...
Vuillermoz, Isabelle, Khattab, Essam, Sablon, Erwin, Ottevaere, Ingrid, Durantel, David, Vieux, Claude, ...
Little is known about hepatitis C virus (HCV) breakthrough during antiviral therapy, although it would help in understanding HCV resistance to current antiviral treatments. To analyse the implication...
Vuillermoz, Isabelle, Khattab, Essam, Sablon, Erwin, Ottevaere, Ingrid, Durantel, David, Vieux, Claude, ...
Little is known about hepatitis C virus (HCV) breakthrough during antiviral therapy, although it would help in understanding HCV resistance to current antiviral treatments. To analyse the implication...
Vuillermoz, Isabelle, Khattab, Essam, Sablon, Erwin, Ottevaere, Ingrid, Durantel, David, Vieux, Claude, ...
Little is known about hepatitis C virus (HCV) breakthrough during antiviral therapy, although it would help in understanding HCV resistance to current antiviral treatments. To analyse the implication...
Validation of the INNO-LIA Syphilis Kit as a Confirmatory Assay for Treponema pallidum Antibodies
Ebel, Anne, Vanneste, Lies, Cardinaels, Martine, Sablon, Erwin, Samson, Isabelle, De Bosschere, Katrien, ...
The commercially available diagnostic tests for syphilis are mostly based on the use of extracted antigens of Treponema pallidum. Pronounced cross-reactivities with other spirochete antigens are...
Zrein, Maan, Louwagie, Joost, Boeykens, Hilde, Govers, Loeki, Hendrickx, Greet, Bosman, Fons, ...
The present study evaluated a new confirmatory assay for antibodies to human T-cell lymphotropic virus type 1 and 2 (HTLV-1 and HTLV-2) proteins performed with serum samples from various commercial...
Lok, Anna S. F., Zoulim, Fabien, Locarnini, Stephen, Mangia, Alessandra, Niro, Grazia, Decraemer, Hilde, ...
Sensitive and early detection of emerging hepatitis B virus (HBV) drug resistance may not only help monitor the viral dynamics associated with lamivudine treatment but could also improve therapeutic...
Hussain, Munira, Chu, Chi-Jen, Sablon, Erwin, Lok, Anna S. F.
Hepatitis B virus (HBV) genotypes may influence HBeAg seroconversion rates, mutational patterns in the precore (PC) and core promoter (CP) regions, severity of liver disease, and response to...
Yuen, Man-Fung, Yuan, He-Jun, Sablon, Erwin, Wong, Danny Ka-Ho, Chan, Annie On-On, Wong, Benjamin Chun-Yu, ...
We sought to examine the role of hepatitis B virus (HBV) genotypes in virological breakthroughs and biochemical flares in patients with YMDD mutations during lamivudine therapy. Virologic...
França, Paulo H. C., González, Jorge E., Munné, M. Silvina, Brandão, Larissa H., Gouvea, Vera S., Sablon, Erwin, ...
A number of reports have indicated an increased risk of cirrhosis and hepatocellular carcinoma in hepatitis B virus (HBV)-infected individuals carrying HBV e antigen (HBeAg)-negative variants....
Yuan, He-Jun, Yuen, Man-Fung, Wong, Danny Ka-Ho, Sum, Siu-Man, Doutreloigne, Joke, Sablon, Erwin, ...
This study was performed to determine the factors for predicting the occurrence of acute exacerbation of hepatitis B virus infection in HBeAg-negative patients. Two hundred and sixteen patients with...
Advances in Molecular Diagnosis of HBV Infection and Drug Resistance
Serological markers are key elements in diagnosing acute hepatitis B virus (HBV) infection and determining its possible evolution towards chronicity. Once treatment of chronic HBV is initiated with...
Hussain, Munira, Fung, Scott, Libbrecht, Evelien, Sablon, Erwin, Cursaro, Carmela, Andreone, Pietro, ...
The INNO-LiPA HBV DR v2 assay is designed to detect hepatitis B virus mutations conveying resistance to lamivudine and adefovir. Our study confirms that this assay can simultaneously detect the...
Validation of the INNO-LIA Syphilis Kit as a Confirmatory Assay for Treponema pallidum Antibodies
Ebel, Anne, Vanneste, Lies, Cardinaels, Martine, Sablon, Erwin, Samson, Isabelle, De Bosschere, Katrien, ...
The commercially available diagnostic tests for syphilis are mostly based on the use of extracted antigens of Treponema pallidum. Pronounced cross-reactivities with other spirochete antigens are...
Zrein, Maan, Louwagie, Joost, Boeykens, Hilde, Govers, Loeki, Hendrickx, Greet, Bosman, Fons, ...
The present study evaluated a new confirmatory assay for antibodies to human T-cell lymphotropic virus type 1 and 2 (HTLV-1 and HTLV-2) proteins performed with serum samples from various commercial...
Lok, Anna S. F., Zoulim, Fabien, Locarnini, Stephen, Mangia, Alessandra, Niro, Grazia, Decraemer, Hilde, ...
Sensitive and early detection of emerging hepatitis B virus (HBV) drug resistance may not only help monitor the viral dynamics associated with lamivudine treatment but could also improve therapeutic...
Hussain, Munira, Chu, Chi-Jen, Sablon, Erwin, Lok, Anna S. F.
Hepatitis B virus (HBV) genotypes may influence HBeAg seroconversion rates, mutational patterns in the precore (PC) and core promoter (CP) regions, severity of liver disease, and response to...
Yuen, Man-Fung, Yuan, He-Jun, Sablon, Erwin, Wong, Danny Ka-Ho, Chan, Annie On-On, Wong, Benjamin Chun-Yu, ...
We sought to examine the role of hepatitis B virus (HBV) genotypes in virological breakthroughs and biochemical flares in patients with YMDD mutations during lamivudine therapy. Virologic...
França, Paulo H. C., González, Jorge E., Munné, M. Silvina, Brandão, Larissa H., Gouvea, Vera S., Sablon, Erwin, ...
A number of reports have indicated an increased risk of cirrhosis and hepatocellular carcinoma in hepatitis B virus (HBV)-infected individuals carrying HBV e antigen (HBeAg)-negative variants....
Yuan, He-Jun, Yuen, Man-Fung, Wong, Danny Ka-Ho, Sum, Siu-Man, Doutreloigne, Joke, Sablon, Erwin, ...
This study was performed to determine the factors for predicting the occurrence of acute exacerbation of hepatitis B virus infection in HBeAg-negative patients. Two hundred and sixteen patients with...
Advances in Molecular Diagnosis of HBV Infection and Drug Resistance
Serological markers are key elements in diagnosing acute hepatitis B virus (HBV) infection and determining its possible evolution towards chronicity. Once treatment of chronic HBV is initiated with...
Hussain, Munira, Fung, Scott, Libbrecht, Evelien, Sablon, Erwin, Cursaro, Carmela, Andreone, Pietro, ...
The INNO-LiPA HBV DR v2 assay is designed to detect hepatitis B virus mutations conveying resistance to lamivudine and adefovir. Our study confirms that this assay can simultaneously detect the...
Noppornpanth, Suwanna, Sablon, Erwin, De Nys, Kathy, Lien, Truong Xuan, Brouwer, Jan, Van Brussel, Marianne, ...
Hepatitis C viruses (HCVs) display a high level of sequence diversity and are currently divided into six genotypes. A line probe assay (LiPA), which targets the 5′ untranslated region (5′UTR) of...
Libbrecht, Evelien, Doutreloigne, Joke, Van De Velde, Hilde, Yuen, Man-Fung, Lai, Ching-Lung, Shapiro, Fred, ...
With the availability of more potent nucleotide/nucleoside analogues, the early detection of drug-resistant mutants of hepatitis B virus (HBV) is important for the strategic treatment of chronic...
Evaluation of Versant Hepatitis C Virus Genotype Assay (LiPA) 2.0▿
Verbeeck, Jannick, Stanley, Mark J., Shieh, Jen, Celis, Linda, Huyck, Els, Wollants, Elke, ...
Hepatitis C virus (HCV) genotyping is a tool used to optimize antiviral treatment regimens. The newly developed Versant HCV genotype assay (LiPA) 2.0 uses sequence information from both the 5′...