Ethel-Michele de Villiers

Presence of papillomavirus sequences in condylomatous lesions of the mamillae and in invasive carcinoma of the breast (2004)

De Villiers, Ethel-Michele, Sandstrom, Robert E, Zur Hausen, Harald, Buck, Charles E

Abstract Background Viruses including Epstein–Barr virus (EBV), a human equivalent of murine mammary tumour virus (MMTV) and human papillomavirus (HPV) have been implicated in the aetiology of...

RISK FACTORS FOR CERVICAL HUMAN PAPILLOMAVIRUS AND HERPES SIMPLEX VIRUS INFECTIONS IN GREENLAND AND DENMARK: A POPULATION-BASED STUDY (1990)

KJAER, SUSANNE K., ENGHOLM, GERDA, TEISEN, CHANTAL, HAUGAARD, BIRTHE J., LYNGE, ELSEBETH, CHRISTENSEN, RENE B., ...

Risk factors for genital human papillomavirus (HPV) types 6/11 and 16/18 and any HPV type as well as for herpes simplex virus type 2 (HSV-2) infections were investigated in a population-based study...

Degenerate and Nested PCR: a Highly Sensitive and Specific Method for Detection of Human Papillomavirus Infection in Cutaneous Warts

Harwood, Catherine A., Spink, Patricia J., Surentheran, T., Leigh, Irene M., De Villiers, Ethel-Michele, McGregor, Jane M., ...

The role of human papillomavirus (HPV) in anogenital carcinogenesis is firmly established, but evidence that supports a similar role in skin remains speculative. Immunosuppressed renal transplant...

The E6 and E7 Proteins of the Cutaneous Human Papillomavirus Type 38 Display Transforming Properties

Caldeira, Sandra, Zehbe, Ingeborg, Accardi, Rosita, Malanchi, Ilaria, Dong, Wen, Giarrè, Marianna, ...

Several studies have suggested the involvement of cutaneous human papillomaviruses (HPVs) in the development of nonmelanoma skin cancers. Here we have characterized the in vitro properties of E7...

Isolation of Multiple TT Virus Genotypes from Spleen Biopsy Tissue from a Hodgkin's Disease Patient: Genome Reorganization and Diversity in the Hypervariable Region

Jelcic, Ilijas, Hotz-Wagenblatt, Agnes, Hunziker, Andreas, Zur Hausen, Harald, De Villiers, Ethel-Michele

We report the isolation of 24 novel genotypes of TT viruses from a surgically removed spleen of a patient with Hodgkin's disease. The sequence analysis of our 24 isolates revealed the remarkable...

Recognition of Conserved Amino Acid Motifs of Common Viruses and Its Role in Autoimmunity

Sospedra, Mireia, Zhao, Yingdong, Zur Hausen, Harald, Muraro, Paolo A, Hamashin, Christa, De Villiers, Ethel-Michele, ...

The triggers of autoimmune diseases such as multiple sclerosis (MS) remain elusive. Epidemiological studies suggest that common pathogens can exacerbate and also induce MS, but it has been difficult...

Results of the First World Health Organization International Collaborative Study of Detection of Human Papillomavirus DNA†

Quint, Wim G. V., Pagliusi, Sonia R., Lelie, Nico, De Villiers, Ethel-Michele, Wheeler, Cosette M.

Twenty-nine laboratories in 12 countries participated in a study to assess the performance of various human papillomavirus (HPV) detection assays through the use of a recombinant HPV DNA standard...

Degenerate and Nested PCR: a Highly Sensitive and Specific Method for Detection of Human Papillomavirus Infection in Cutaneous Warts

Harwood, Catherine A., Spink, Patricia J., Surentheran, T., Leigh, Irene M., De Villiers, Ethel-Michele, McGregor, Jane M., ...

The role of human papillomavirus (HPV) in anogenital carcinogenesis is firmly established, but evidence that supports a similar role in skin remains speculative. Immunosuppressed renal transplant...

The E6 and E7 Proteins of the Cutaneous Human Papillomavirus Type 38 Display Transforming Properties

Caldeira, Sandra, Zehbe, Ingeborg, Accardi, Rosita, Malanchi, Ilaria, Dong, Wen, Giarrè, Marianna, ...

Several studies have suggested the involvement of cutaneous human papillomaviruses (HPVs) in the development of nonmelanoma skin cancers. Here we have characterized the in vitro properties of E7...

Isolation of Multiple TT Virus Genotypes from Spleen Biopsy Tissue from a Hodgkin's Disease Patient: Genome Reorganization and Diversity in the Hypervariable Region

Jelcic, Ilijas, Hotz-Wagenblatt, Agnes, Hunziker, Andreas, Zur Hausen, Harald, De Villiers, Ethel-Michele

We report the isolation of 24 novel genotypes of TT viruses from a surgically removed spleen of a patient with Hodgkin's disease. The sequence analysis of our 24 isolates revealed the remarkable...

Recognition of Conserved Amino Acid Motifs of Common Viruses and Its Role in Autoimmunity

Sospedra, Mireia, Zhao, Yingdong, Zur Hausen, Harald, Muraro, Paolo A, Hamashin, Christa, De Villiers, Ethel-Michele, ...

The triggers of autoimmune diseases such as multiple sclerosis (MS) remain elusive. Epidemiological studies suggest that common pathogens can exacerbate and also induce MS, but it has been difficult...

Results of the First World Health Organization International Collaborative Study of Detection of Human Papillomavirus DNA†

Quint, Wim G. V., Pagliusi, Sonia R., Lelie, Nico, De Villiers, Ethel-Michele, Wheeler, Cosette M.

Twenty-nine laboratories in 12 countries participated in a study to assess the performance of various human papillomavirus (HPV) detection assays through the use of a recombinant HPV DNA standard...

E6/E7 Expression of Human Papillomavirus Type 20 (HPV-20) and HPV-27 Influences Proliferation and Differentiation of the Skin in UV-Irradiated SKH-hr1 Transgenic Mice▿

Michel, Angelika, Kopp-Schneider, Annette, Zentgraf, Hanswalter, Gruber, Achim D., De Villiers, Ethel-Michele

The functional role of UV irradiation, in combination with the E6 and E7 proteins of the cutaneous human papillomavirus (HPV) types in the malignant conversion of benign papillomatous lesions, has...

In Vivo and In Vitro Intragenomic Rearrangement of TT Viruses▿

Leppik, Ludmila, Gunst, Karin, Lehtinen, Matti, Dillner, Joakim, Streker, Karin, De Villiers, Ethel-Michele

The in vitro replication of the Torque teno virus (TT virus) tth8 full-length genome and particle formation in a Hodgkin's lymphoma-derived cell line after transfection with cloned viral DNA were...

E7 Oncoprotein of Novel Human Papillomavirus Type 108 Lacking the E6 Gene Induces Dysplasia in Organotypic Keratinocyte Cultures ▿

Nobre, Rui Jorge, Herráez-Hernández, Elsa, Fei, Jian-Wei, Langbein, Lutz, Kaden, Sylvia, Gröne, Hermann-Josef, ...

The genome organization of the novel human papillomavirus type 108 (HPV108), isolated from a low-grade cervical lesion, deviates from those of other HPVs in lacking an E6 gene. The three related HPV...