Moret, Etienne, Franzini, Livia, Schlosser, Manfred
When treated with 2 equiv of a BuLi/KOCMe3 mixt., terminal olefins carrying unprotected OH or CO2H groups generate allylmetal intermediates which are trapped with Me3SiCl to afford functionalized...
Franzini, Livia, Moret, Etienne, Schlosser, Manfred
Alk-2-enylpotassium compds. having endo conformation are synthetically very valuable precursors of (Z)-olefinic derivs. substituted at the outward allylic position. They may be generated by...
Schlosser, Manfred, Desponds, Olivier, Lehmann, Ruth, Moret, Etienne, Rauchschwalbe, Guenter
A review with 64 refs., including discussion of the structural flexibility of organometallic species, the stereochem. of 2-alkenylmetal compds., and the origin of the endo effect. [on SciFinder (R)]
1,(w-1)-Dienes: solvent controlled unilateral or bilateral metalation (1991)
Moret, Etienne, Desponds, Olivier, Schlosser, Manfred
In hexane, i.e. under heterogeneous conditions, 1,(w - 1)-dienes readily undergo double deprotonation to give bis(allylmetal) intermediates. In THF at -75 or -50 Deg, however, only monometalation...
1-(Triphenylmethyl)allylpotassium: conformational preference and [1,2]-rearrangement (1988)
Moret, Etienne, Fuerrer, Juerg, Schlosser, Manfred
Upon treatment with the superbasic 1:1 mixt. of BuLi and Me3COK, cis- and trans-1,1,1-triphenyl-2-butene as well as 4,4,4-triphenyl-1-butene undergo a hydrogen/metal exchange to afford...
Moret, Etienne, Schneider, Philippe, Margot, Christian, Staehle, Manfred, Schlosser, Manfred
Hexane suspensions of Me3SiCH2K or BuLi/Me3COK deprotonated 1-methylcyclohexene almost exclusively at the Me group. In contrast 1,4-dimethyl-1,2,3,6-tetrahydropyridine and...
Solvent-controlled additions of organotitanium reagents to olefinic double bonds (1985)
Moret, Etienne, Schlosser, Manfred
Under carefully chosen working conditions (solvent, temp.), methyltitanium reagents smoothly convert homoallyl alcs. having a terminal double-bond into (E)-3-penten-1-ols, whereas nonterminal...
Moret, Etienne, Schlosser, Manfred
Consecutive treatment of endo-butenylpotassium or endo-1-(tetrahydropyranyloxy)-exo-butenyllithium with FB(OMe)2 and pentanal at -75 Deg affords an erythro- and, threo-adduct, resp., which on...
Facile and selective metalation of 7-dehydrocholesterol (pro-vitamin D3) (1984)
Moret, Etienne, Schlosser, Manfred
Successive treatment of 7-dehydrocholesterol (I) with Me3SiCH2K in THF, dry ice, mineral acid, and diazomethane gives a regioisomerically pure, homoconjugated ester II as a diastereomeric mixt., the...
Pheromones as test targets for stereoselective carbon-carbon linking methods (1983)
Fujita, Katsuramaru, Cloux, Roland, Tuong, Huynh Ba, Moret, Etienne, Schaub, Bruno, Schlosser, Manfred
Review with 30 refs. [on SciFinder (R)]
Fujita, Katsuramaru, Moret, Etienne, Schlosser, Manfred
Upon treatment with Me2TiCl2 or Me3Al in the presence of TiCl4, an H atom at the olefinic 4-position is replaced by a Me group. Terminal homoallyl alcs. afford E isomers. If the double bond is...
Application des allylpotassiums à la synthèse organique / (1980)
Thèse sciences Lausanne. (PE).