F. Cavalli

Publication List Details

Period

1900 - 2009

Number

199

Co-Authors

APPROXIMATION OF 2D AND 3D MODEL OF CHEMOTACTIC CELL MOVEMENTS IN VASCULOGENESIS (2009)

F. Cavalli, A. Gamba, G. Naldi, M. Semplice

Cell migration plays a central role in a wide variety of biological phenomena. In the case of chemotaxis, cells (or an organism) move in response to a chemical gradient. Chemotaxis underlies many...

What can we learn about ship emission inventories from measurements of air pollutants over the Mediterranean Sea? (2009)

E. Marmer, F. Dentener, J. V. Aardenne, F. Cavalli, E. Vignati, K. Velchev, ...

Ship emission estimates diverge widely for all chemical compounds for several reasons: use of different methodologies (bottom-up or top-down), activity data and emission factors can easily result in...

Long-term outcome following Helicobacter pylori eradication in a retrospective study of 105 patients with localized gastric marginal zone B-cell lymphoma of MALT type (2009)

Stathis, A., Chini, C., Bertoni, F., Proserpio, I., Capella, C., Mazzucchelli, L., ...

Background: Treatment aimed at eradicating Helicobacter pylori infection results in lymphoma remission in most localized gastric mucosa-associated lymphoid tissue (MALT) lymphomas. The aim of this...

What can we learn about ship emission inventories from measurements of air pollutants over the Mediterranean Sea? (2009)

E. Marmer, F. Dentener, J. V. Aardenne, F. Cavalli, E. Vignati, K. Velchev, ...

Ship emission estimates diverge widely for all chemical compounds for several reasons: use of different methodologies (bottom-up or top-down), activity data and emission factors can easily result in...

High order relaxed schemes for nonlinear reaction diffusion problems in nonconservative form (2008)

Cavalli, F., Semplice, M.

Different relaxation approximations to partial differential equations, including conservation laws, Hamilton-Jacobi equations, convection-diffusion problems, gas dynamics problems, have been recently...

The role of VOC oxidation products in continental new particle formation (2008)

Laaksonen, A., Kulmala, M., O'Dowd, C. D., Joutsensaari, J., Vaattovaara, P., Mikkonen, S., ...

Aerosol physical and chemical properties and trace gas concentrations were measured during the QUEST field campaign in March?April 2003, in Hyytiälä, Finland. Our aim was to understand the role of...

The role of VOC oxidation products in continental new particle formation (2008)

Laaksonen, A., Kulmala, M., O'Dowd, C. D., Joutsensaari, J., Vaattovaara, P., Mikkonen, S., ...

Aerosol physical and chemical properties and trace gas concentrations were measured during the QUEST field campaign in March?April 2003, in Hyytiälä, Finland. Our aim was to understand the role of...

Primary diffuse large B-cell lymphoma of the breast: prognostic factors and outcomes of a study by the International Extranodal Lymphoma Study Group (2008)

Ryan, G., Martinelli, G., Kuper-Hommel, M., Tsang, R., Pruneri, G., Yuen, K., ...

Background: Primary diffuse large B-cell lymphoma (DLBCL) of breast is rare. We aimed to define clinical features, prognostic factors, patterns of failure, and treatment outcomes. Patients and...

The role of VOC oxidation products in continental new particle formation (2008)

A. Laaksonen, M. Kulmala, C. D. O'Dowd, J. Joutsensaari, P. Vaattovaara, S. Mikkonen, ...

Aerosol physical and chemical properties and trace gas concentrations were measured during the QUEST field campaign in March–April 2003, in Hyytiälä, Finland. Our aim was to understand the...

Primary diffuse large B-cell lymphoma of the breast: prognostic factors and outcomes of a study by the International Extranodal Lymphoma Study Group (2008)

Ryan, G., Martinelli, G., Kuper-Hommel, M., Tsang, R., Pruneri, G., Yuen, K., ...

Background: Primary diffuse large B-cell lymphoma (DLBCL) of breast is rare. We aimed to define clinical features, prognostic factors, patterns of failure, and treatment outcomes. Patients and...

Ocular adnexal MALT lymphoma: an intriguing model for antigen-driven lymphomagenesis and microbial-targeted therapy (2008)

Ferreri, A. J. M., Dolcetti, R., Doglioni, C., Giordano Resti, A., Politi, L. S., ...

Non-Hodgkin's lymphomas constitute one half of malignancies arising in the orbit and the ocular adnexae. Mucosa-associated lymphoid tissue (MALT)-type lymphoma is the most common histological...

Nucleation and growth of new particles in Po Valley, Italy (2007)

A. Hamed, J. Joutsensaari, S. Mikkonen, L. Sogacheva, M. Dal Maso, M. Kulmala, ...

Aerosol number distribution measurements are reported at San Pietro Capofiume (SPC) station (44°39' N, 11°37' E) for the time period 2002–2005. The station is located in Po...

The role of VOC oxidation products in continental new particle formation (2007)

Laaksonen, A., Kulmala, M., O'Dowd, C. D., Joutsensaari, J., Vaattovaara, P., Mikkonen, S., ...

Aerosol physical and chemical properties and trace gas concentrations were measured during the QUEST field campaign in March?April, 2003, in Hyytiälä, Finland. Our aim was to understand the role of...

Elemental and organic carbon in PM10: a one year measurement campaign within the European Monitoring and Evaluation Programme EMEP (2007)

Yttri, K. E., Aas, W., Bjerke, A., Cape, J. N., Cavalli, F., Ceburnis, D., ...

In the present study, ambient aerosol (PM10) concentrations of elemental carbon (EC), organic carbon (OC), and total carbon (TC) are reported for 12 European rural background sites and two urban...

Nucleation and growth of new particles in Po Valley, Italy (2007)

Hamed, A., Joutsensaari, J., Mikkonen, S., Sogacheva, L., Dal Maso, M., Kulmala, M., ...

Aerosol number distribution measurements are reported at San Pietro Capofiume (SPC) station (44°39' N, 11°37' E) for the time period 2002?2005. The station is located in Po Valley, the largest...

The role of VOC oxidation products in continental new particle formation (2007)

Laaksonen, A., Kulmala, M., O'Dowd, C. D., Joutsensaari, J., Vaattovaara, P., Mikkonen, S., ...

Aerosol physical and chemical properties and trace gas concentrations were measured during the QUEST field campaign in March?April, 2003, in Hyytiälä, Finland. Our aim was to understand the role of...

Elemental and organic carbon in PM10: a one year measurement campaign within the European Monitoring and Evaluation Programme EMEP (2007)

Yttri, K. E., Aas, W., Bjerke, A., Cape, J. N., Cavalli, F., Ceburnis, D., ...

In the present study, ambient aerosol (PM10) concentrations of elemental carbon (EC), organic carbon (OC), and total carbon (TC) are reported for 12 European rural background sites and two urban...

Nucleation and growth of new particles in Po Valley, Italy (2007)

Hamed, A., Joutsensaari, J., Mikkonen, S., Sogacheva, L., Dal Maso, M., Kulmala, M., ...

Aerosol number distribution measurements are reported at San Pietro Capofiume (SPC) station (44°39' N, 11°37' E) for the time period 2002?2005. The station is located in Po Valley, the largest...

Elemental and organic carbon in PM10: a one year measurement campaign within the European Monitoring and Evaluation Programme EMEP (2007)

K. E. Yttri, W. Aas, A. Bjerke, J. N. Cape, F. Cavalli, D. Ceburnis, ...

In the present study, ambient aerosol (PM10) concentrations of elemental carbon (EC), organic carbon (OC), and total carbon (TC) are reported for 12 European rural background sites and two urban...

The role of VOC oxidation products in continental new particle formation (2007)

A. Laaksonen, M. Kulmala, C. D. O'Dowd, J. Joutsensaari, P. Vaattovaara, S. Mikkonen, ...

Aerosol physical and chemical properties and trace gas concentrations were measured during the QUEST field campaign in March–April, 2003, in Hyytiälä, Finland. Our aim was to understand the...

3D simulations of early blood vessel formation (2006)

Cavalli, F., Gamba, A., Naldi, G., Semplice, M., Valdembri, D., Serini, G.

Blood vessel networks form by spontaneous aggregation of individual cells migrating toward vascularization sites (vasculogenesis). A successful theoretical model of two dimensional experimental...

Size and composition measurements of background aerosol and new particle growth in a Finnish forest during QUEST 2 using an Aerodyne Aerosol Mass Spectrometer (2006)

J. D. Allan, M. R. Alfarra, K. N. Bower, H. Coe, J. T. Jayne, D. R. Worsnop, ...

The study of the growth of nucleation-mode particles is important, as this prevents their loss through diffusion and allows them to reach sizes where they may become effective cloud condensation...

Characterization of the organic composition of aerosols from Rondônia, Brazil, during the LBA-SMOCC 2002 experiment and its representation through model compounds (2006)

S. Decesari, S. Fuzzi, M. C. Facchini, M. Mircea, L. Emblico, F. Cavalli, ...

The chemical composition of carbonaceous aerosols collected during the LBA-SMOCC field experiment, conducted in Rondônia, Brazil, in 2002 during the transition from the dry to the wet season,...

Size-segregated aerosol chemical composition at a boreal site in southern Finland, during the QUEST project (2006)

F. Cavalli, M. C. Facchini, S. Decesari, L. Emblico, M. Mircea, N. R. Jensen, ...

Size-segregated aerosol samples were collected during the QUEST field campaign at Hyytiälä, a boreal forest site in Southern Finland, during spring 2003. Aerosol samples were selectively...

Nucleation and growth of new particles in Po Valley, Italy (2006)

Hamed, A., Joutsensaari, J., Mikkonen, S., Sogacheva, L., Dal Maso, M., Kulmala, M., ...

Aerosol number distribution measurements are reported at San Pietro Capofiume (SPC) station (44°39' N, 11°37' E) for the time period 2002?2005. The station is located in Po Valley, the largest...

Size-segregated aerosol chemical composition at a boreal site in southern Finland, during the QUEST project (2006)

Cavalli, F., Facchini, M. C., Decesari, S., Emblico, L., Mircea, M., Jensen, N. R., ...

Size-segregated aerosol samples were collected during the QUEST field campaign at Hyytiälä, a boreal forest site in Southern Finland, during spring 2003. Aerosol samples were selectively collected...

Characterization of the organic composition of aerosols from Rondônia, Brazil, during the LBA-SMOCC 2002 experiment and its representation through model compounds (2006)

Decesari, S., Fuzzi, S., Facchini, M. C., Mircea, M., Emblico, L., Cavalli, F., ...

The chemical composition of carbonaceous aerosols collected during the LBA-SMOCC field experiment, conducted in Rondônia, Brazil, in 2002 during the transition from the dry to the wet season, was...

Size and composition measurements of background aerosol and new particle growth in a Finnish forest during QUEST 2 using an Aerodyne Aerosol Mass Spectrometer (2006)

Allan, J. D., Alfarra, M. R., Bower, K. N., Coe, H., Jayne, J. T., Worsnop, D. R., ...

The study of the growth of nucleation-mode particles is important, as this prevents their loss through diffusion and allows them to reach sizes where they may become effective cloud condensation...

Nucleation and growth of new particles in Po Valley, Italy (2006)

Hamed, A., Joutsensaari, J., Mikkonen, S., Sogacheva, L., Dal Maso, M., Kulmala, M., ...

Aerosol number distribution measurements are reported at San Pietro Capofiume (SPC) station (44°39' N, 11°37' E) for the time period 2002?2005. The station is located in Po Valley, the largest...

Size-segregated aerosol chemical composition at a boreal site in southern Finland, during the QUEST project (2006)

Cavalli, F., Facchini, M. C., Decesari, S., Emblico, L., Mircea, M., Jensen, N. R., ...

Size-segregated aerosol samples were collected during the QUEST field campaign at Hyytiälä, a boreal forest site in Southern Finland, during spring 2003. Aerosol samples were selectively collected...

Characterization of the organic composition of aerosols from Rondônia, Brazil, during the LBA-SMOCC 2002 experiment and its representation through model compounds (2006)

Decesari, S., Fuzzi, S., Facchini, M. C., Mircea, M., Emblico, L., Cavalli, F., ...

The chemical composition of carbonaceous aerosols collected during the LBA-SMOCC field experiment, conducted in Rondônia, Brazil, in 2002 during the transition from the dry to the wet season, was...

Size and composition measurements of background aerosol and new particle growth in a Finnish forest during QUEST 2 using an Aerodyne Aerosol Mass Spectrometer (2006)

Allan, J. D., Alfarra, M. R., Bower, K. N., Coe, H., Jayne, J. T., Worsnop, D. R., ...

The study of the growth of nucleation-mode particles is important, as this prevents their loss through diffusion and allows them to reach sizes where they may become effective cloud condensation...

Prevalence of hepatitis C virus and GB-C virus infection among patients with B-cell non-Hodgkin's lymphoma: A case-control study of the International Extranodal Lymphoma Study Group (2006)

Guidicelli-Nicolosi, S., Rodriguez-Abreu, D., Conconi, A., Grisanti, S., Lopez-Guillermo, A., Johnson, P.W., ...

Background In regions with high prevalence of hepatitis C virus (HCV) the frequency of this infection is higher in patients with B-cell non-Hodgkin lymphoma (B-NHL). Patients with HCV infection...

Importance of the organic aerosol fraction for modeling aerosol hygroscopic growth and activation: a case study in the Amazon Basin (2005)

M. Mircea, M. C. Facchini, S. Decesari, F. Cavalli, L. Emblico, S. Fuzzi, ...

The aerosol in the Amazon basin is dominated throughout the year by organic matter, for the most part soluble in water. In this modeling study, we show how the knowledge of water-soluble organic...

Size-segregated aerosol chemical composition at a boreal site in southern Finland, during the QUEST project (2005)

Cavalli, F., Facchini, M. C., Decesari, S., Emblico, L., Mircea, M., Jensen, N. R., ...

Size-segregated aerosol samples were collected during the QUEST field campaign at Hyytiälä, a boreal forest site in Southern Finland, during spring 2003. Aerosol samples were selectively collected...

Size and composition measurements of background aerosol and new particle growth in a Finnish forest during QUEST 2 using an Aerodyne Aerosol Mass Spectrometer (2005)

Allan, J. D., Alfarra, M. R., Bower, K. N., Coe, H., Jayne, J. T., Worsnop, D. R., ...

The study of the growth of nucleation-mode particles is important, as this prevents their loss through diffusion and allows them to reach sizes where they may become effective cloud condensation...

Characterization of the organic composition of aerosols from Rondônia, Brazil, during the LBA-SMOCC 2002 experiment and its representation through model compounds (2005)

Decesari, S., Fuzzi, S., Facchini, M. C., Mircea, M., Emblico, L., Cavalli, F., ...

The chemical composition of carbonaceous aerosols collected during the LBA-SMOCC field experiment, conducted in Rondônia, Brazil, in 2002 during the transition from the dry to the wet season, was...

Importance of the organic aerosol fraction for modeling aerosol hygroscopic growth and activation: a case study in the Amazon Basin (2005)

Mircea, M., Facchini, M. C., Decesari, S., Cavalli, F., Emblico, L., Fuzzi, S., ...

The aerosol in the Amazon basin is dominated throughout the year by organic matter, for the most part soluble in water. In this modeling study, we show how the knowledge of water-soluble organic...

Importance of the organic aerosol fraction for modeling aerosol hygroscopic growth and activation: a case study in the Amazon Basin (2005)

Mircea, M., Facchini, M. C., Decesari, S., Cavalli, F., Emblico, L., Fuzzi, S., ...

The aerosol in the Amazon basin is dominated throughout the year by organic matter, for the most part soluble in water. In this modeling study, we show how the knowledge of water-soluble organic...

Size-segregated aerosol chemical composition at a boreal site in southern Finland, during the QUEST project (2005)

Cavalli, F., Facchini, M. C., Decesari, S., Emblico, L., Mircea, M., Jensen, N. R., ...

Size-segregated aerosol samples were collected during the QUEST field campaign at Hyytiälä, a boreal forest site in Southern Finland, during spring 2003. Aerosol samples were selectively collected...

Size and composition measurements of background aerosol and new particle growth in a Finnish forest during QUEST 2 using an Aerodyne Aerosol Mass Spectrometer (2005)

Allan, J. D., Alfarra, M. R., Bower, K. N., Coe, H., Jayne, J. T., Worsnop, D. R., ...

The study of the growth of nucleation-mode particles is important, as this prevents their loss through diffusion and allows them to reach sizes where they may become effective cloud condensation...

Characterization of the organic composition of aerosols from Rondônia, Brazil, during the LBA-SMOCC 2002 experiment and its representation through model compounds (2005)

Decesari, S., Fuzzi, S., Facchini, M. C., Mircea, M., Emblico, L., Cavalli, F., ...

The chemical composition of carbonaceous aerosols collected during the LBA-SMOCC field experiment, conducted in Rondônia, Brazil, in 2002 during the transition from the dry to the wet season, was...

Importance of the organic aerosol fraction for modeling aerosol hygroscopic growth and activation: a case study in the Amazon Basin (2005)

Mircea, M., Facchini, M. C., Decesari, S., Cavalli, F., Emblico, L., Fuzzi, S., ...

The aerosol in the Amazon basin is dominated throughout the year by organic matter, for the most part soluble in water. In this modeling study, we show how the knowledge of water-soluble organic...

Importance of the organic aerosol fraction for modeling aerosol hygroscopic growth and activation: a case study in the Amazon Basin (2005)

Mircea, M., Facchini, M. C., Decesari, S., Cavalli, F., Emblico, L., Fuzzi, S., ...

The aerosol in the Amazon basin is dominated throughout the year by organic matter, for the most part soluble in water. In this modeling study, we show how the knowledge of water-soluble organic...

In vitro activity of cyclin-dependent kinase inhibitor CYC202 (Seliciclib, R-roscovitine) in mantle cell lymphomas (2005)

Lacrima, K., Valentini, A., Lambertini, C., Taborelli, M., Rinaldi, A., Zucca, E., ...

Background:: Mantle cell lymphoma (MCL) has the worst prognosis of all B-cell lymphomas and has poor response to conventional therapy. It is characterized by the presence of a chromosomal...

In vitro activity of cyclin-dependent kinase inhibitor CYC202 (Seliciclib, R-roscovitine) in mantle cell lymphomas (2005)

Lacrima, K., Valentini, A., Lambertini, C., Taborelli, M., Rinaldi, A., Zucca, E., ...

Background: Mantle cell lymphoma (MCL) has the worst prognosis of all B-cell lymphomas and has poor response to conventional therapy. It is characterized by the presence of a chromosomal...

Anthracycline-based chemotherapy as primary treatment for intravascular lymphoma (2004)

Ferreri, A. J. M., Campo, E., Ambrosetti, A., Ilariucci, F., Seymour, J. F., Willemze, R., ...

Background: Optimal therapeutic management of intravascular lymphoma (IVL) lacks precise guidelines. Patients and methods: The clinico-pathological features of 38 HIV-negative patients with IVL were...

Mass closure on the chemical species in size-segregated atmospheric aerosol collected in an urban area of the Po Valley, Italy (2003)

E. Matta, M. C. Facchini, S. Decesari, M. Mircea, F. Cavalli, S. Fuzzi, ...

A complete size segregated chemical characterisation was carried out for aerosol samples collected in the urban area of Bologna over a period of one year, using five-stage low pressure Berner...

Mass closure on the chemical species in size-segregated atmospheric aerosol collected in an urban area of the Po Valley, Italy (2003)

Matta, E., Facchini, M. C., Decesari, S., Mircea, M., Cavalli, F., Fuzzi, S., ...

A complete size segregated chemical characterisation was carried out for aerosol samples collected in the urban area of Bologna over a period of one year, using five-stage low pressure Berner...

Mass closure on the chemical species in size-segregated atmospheric aerosol collected in an urban area of the Po Valley, Italy (2003)

Matta, E., Facchini, M. C., Decesari, S., Mircea, M., Cavalli, F., Fuzzi, S., ...

A complete size segregated chemical characterisation was carried out for aerosol samples collected in the urban area of Bologna over a period of one year, using five-stage low pressure Berner...

Chemical mass balance of size-segregated atmospheric aerosol in an urban area of the Po Valley, Italy (2002)

Matta, E., Facchini, M. C., Decesari, S., Mircea, M., Cavalli, F., Fuzzi, S., ...

A complete size segregated chemical characterisation was carried out for aerosol samples collected in the urban area of Bologna over a period of one year, using five-stage low pressure Berner...

Chemical mass balance of size-segregated atmospheric aerosol in an urban area of the Po Valley, Italy (2002)

Matta, E., Facchini, M. C., Decesari, S., Mircea, M., Cavalli, F., Fuzzi, S., ...

A complete size segregated chemical characterisation was carried out for aerosol samples collected in the urban area of Bologna over a period of one year, using five-stage low pressure Berner...

The beyond the standard model working group: summary report (2002)

Azuelos, G., Gunion, J., Hewett, J., Landsberg, K., Matchev, K., Paige, F., ...

In this working group we have investigated a number of aspects of searches for new physics beyond the Standard Model (SM) at the running or planned TeV-scale colliders. For the most part, we have...

Chemical mass balance of size-segregated atmospheric aerosol in an urban area of the Po Valley, Italy (2002)

E. Matta, M. C. Facchini, S. Decesari, M. Mircea, F. Cavalli, S. Fuzzi, ...

A complete size segregated chemical characterisation was carried out for aerosol samples collected in the urban area of Bologna over a period of one year, using five-stage low pressure Berner...

Relevance of intraocular involvement in the management of primary central nervous system lymphomas (2002)

Ferreri, A. J. M., Reni, M., Pasini, F., Gubkin, A., Tirelli, U., ...

Background Reported data regarding intraocular lymphoma (IOL) management are anecdotal. Cases of IOL included in an international multicentre series of 378 immunocompetent patients with primary...

Treatment of childhood Wilms' tumor without radiotherapy in Nicaragua (2002)

Baez, F., Fossati Bellani, F., Ocampo, E., Conter, V., Flores, A., Gutierrez, T., ...

Background Recent trends in therapeutic strategies for Wilms’ tumor are based on an attempt to reduce or omit radiotherapy (RT) in a sizable fraction of patients. We report here the clinical and...

Microsatellite instability: Application in hereditary non-polyposis colorectal cancer (2001)

Saletti, P., Edwin, I. Dove, Pack, K., Cavalli, F., Atkin, W. S.

Colorectal cancer (CRC) is a significant cause of mortality in Western populations. About 15% of CRC patients report a family history of the disease. Studies on individuals with a genetic...

Proposing phase I studies: Patients', relatives', nurses' and specialists' perceptions (2000)

Tomamichel, M., Jaime, H., Degrate, A., De Jong, J., Pagani, O., Cavalli, F., ...

Purpose: As of now the primary objective of studies on informed consent in phase I trials has been to assess patients' expectations and reasons for participation. We have previously shown that the...

Docetaxel (Taxotere(R))-cisplatin (TC): An effective drug combination in gastric carcinoma (2000)

Roth, A. D., Maibach, R., Martinelli, G., Fazio, N., Aapro, M. S., Pagani, O., ...

Purpose: A multi-centric trial was performed to explore the clinical activity, in terms of response and toxicity (primary objectives), duration of response and survival (secondary objectives), of...

START: A European state-of-the-art on-line instrument for clinical oncologists (1999)

Casali, P., Licitra, L., Tondini, C., De Braud, F., Bruzzi, P., Costa, A., ...

START (‘State-of-the-Art Oncology in Europe’), a freely available resource on the Internet, is a European ‘information base’ of current clinical approaches to human tumours. Its aim is to...

Microsatellite instability in gastric MALT lymphomas and other associated neoplasms (1999)

Furlan, D., Bertoni, F., Cerutti, R., Taborelli, M., Pinotti, G., Roggero, E., ...

Background: Microsatellite instability (MSI), caused by a reduced efficacy of the DNA mismatch repair (MMR) machinery, represents a type of genomic instability frequently detected in HNPCC spectrum...

Stage-modified international prognostic index effectively predicts clinical outcome of localized primary gastric diffuse large B-cell lymphoma (1999)

Cortelazzo, S., Rossi, A., Roggero, E., Oldani, E., Zucca, E., Tondini, C., ...

Background: The definition of prognostic parameters in early stages of gastric lymphoma is still controversial. The aim of this retrospective analysis was to assess the value of the stage-modified...

Rare syndromes in Hodgkin's disease (1998)

Cavalli, F.

The presentation of Hodgkin's disease is in the vast majority of cases rather classical. Howewer, there are some rare syndromes which might be very puzzling. In this contribution, we will discuss...

Menstrual cycle and timing of breast surgery in premenopausal node-positive breast cancer: Results of the International Breast Cancer Study Group (IBCSG) Trial VI (1997)

Goldhirsch, A., Gelber, R. D., Castiglione, M., O'Neill, A., Thürlimann, B., ...

Purpose It has been postulated that breast cancer surgery performed during the follicular phase of the menstrual cycle is associated with poorer outcome. Patients and methods We tested this...

Treatment of childhood Hodgkin's disease with COPP or COPP-ABV (hybrid) without radiotherapy in Nicaragua (1997)

Baez, F., Ocampo, E., Conter, V., Flores, A., Gutierrez, T., Malta, A., ...

Background: Childhood Hodgkin's disease (HD) in low-income countries has been reported to have distinct presenting features, including a high prevalence of the mixed cellularity subtype, which also...

Post-remission therapy of adult acute myeloid leukaemia: One cycle of high-dose versus standard-dose cytarabine (1997)

Fopp, M., Fey, M. F., Bacchi, M., Cavalli, F., Gmuer, J., Jacky, E., ...

Background: Intensification of post-remission therapy improves the cure rate of acute myeloid leukemia (AML) but is often accompanied by unacceptable toxicity. From 1985 to 1992 the Swiss Group for...

Dose-finding study of paclitaxel and cyclophosphamide in advanced breast cancer (1997)

Pagani, O., Sessa, C., Martinelli, G., Cerny, T., De Jong, J., Goldhirsch, A., ...

Background The toxicity profile of prolonged infusions of paclitaxel in combination with cyclophosphamide in metastat-ic breast cancer has already been defined. The objective of this dose-finding...

The effect of adjuvant prednisone combined with CMF on patterns of relapse and occurrence of second malignancies in patients with breast cancer (1996)

Marini, G., Murray, S., Goldhirsch, A., Gelber, R. D., Castiglione-Gertsch, M., Price, K. N., ...

Background: The addition of low-dose prednisone (p) to the adjuvant regimen of cyclophosphamide, methotrexate, 5-fluorouracil (CMF) allowed patients to receive a larger dose of cytotoxics when...

First-line fadrozole HCI (CGS 16949A) versus tamoxifen in postmenopausal women with advanced breast cancer: Prospective randomised trial of the Swiss Group for Clinical Cancer Research SAKK 20/88 (1996)

Thürlimann, B., Beretta, K., Bacchi, M., Castiglione-Gertsch, M., Goldhirsch, A., Jungi, W. F., ...

Background: In a phase III randomized trial, we compared the effectiveness and tolerability of fadrozole (CGS 16949A), a non-steroidal aromatase inhibitor, to tamoxifen as first-line endocrine...

Low-dose continuous intravenous infusion of 5-fluorouracil for metastatic breast cancer (1996)

Regazzoni, S., Pesce, G., Marini, G., Cavalli, F., Goldhirsch, A.

Background: Third-line chemotherapies for advanced breast cancer are difficult to tailor to the individual patient because of reduced tolerance and significant toxicity. Treatment with a continuous...

Clinical significance of bcl-2 (MBR)/JH rearrangement in the peripheral blood of patients with diffuse large B-cell lymphomas (1996)

Zucca, E., Bertoni, F., Bosshard, G., Roggero, E., Ceresa, E., Sanna, P., ...

Background: Approximately one-fourth of diffuse large B-cell lymphomas (DLCL) carry the bcl-2(MBR)/JH rearrangement caused by the t(14;18) translocation. The clinical sigmlicance of this...

Granulocyte growth factors: achieving a consensus (1995)

Cavalli, F, Cortés-Funes, H, Gatell, J M, Gianni, A M, Khayat, D, ...

A consensus meeting held under the auspices of the European School of Oncology concluded that the use of granulocyte growth factors is definitely indicated, or acceptable given existing evidence, in...

Informed consent for phase I studies: Evaluation of quantity and quality of information provided to patients (1995)

Tomamichel, M., Sessa, C., Herzig, S., De Jong, J., Pagani, O., Willems, Y., ...

Background The process by which patients are informed and their consent is obtained in phase I trials has thus far been only marginally studied. Since 1986 we have followed an oral procedure,...

Interferon-alpha for induction and maintenance in multiple myeloma: Results of two multicenter randomized trials and summary of other studies (1995)

Ludwig, H., Cohen, A. M., Polliack, A., Huber, H., Nachbaur, D., ...

Background: Interferon (IFN) treatment trials in multiple myeloma have yielded discordant results regarding response rates, maintenance duration, and survival times. Further randomized trials and...

Routine tests during follow-up of patients after primary treatment for operable breast cancer (1995)

Crivellari, D., Price, K. N., Hagen, M., Goldhirsch, A., Gelber, R. D., Castiglione, M., ...

Background: Follow-up tests for patients after diagnosis and primary treatment of breast cancer are routinely performed. However, the usefulness of these follow-up parameters remains unclear. We...

Granulocyte growth factors: Achieving a consensus (1995)

Boogaerts, M., Cavalli, F., Cortés-Funes, H., Gatell, J. M., Gianni, A. M., Khayat, D., ...

A consensus meeting held under the auspices of the European School of Oncology concluded that the use of granulocyte growth factors is definitely indicated, or acceptable given existing evidence, in...

Patterns of survival in mantle cell lymphoma (1995)

Zucca, E., Roggero, E., Pinotti, G., Pedrinis, E., Cappella, C., Venco, A., ...

Background: The term mantle cell lymphoma (MCL) describes a subtype of non-Hodgkin's lymphoma that includes those lymphomas previously defined as centrocytic lymphoma, intermediate lymphocytic...

The International (Ludwig) Breast Cancer Study Group Trials I-IV: 15 years follow-up (1994)

Castiglione-Gertsch, M., Johnsen, C., Goldhirsch, A., Gelber, R. D., Rudenstam, C. M., Collins, J., ...

Background Adjuvant systemic therapy prolongs disease-free and overall survival in both pre- and postmenopausal patients. Available data shown benefit from multi-agent chemotherapy, prolonged...

Phase I study of the novel distamycin derivative tallimustine (FCE 24517) (1994)

Sessa, C., Pagani, O., Zurlo, M. G., De Jong, J., Hofmann, C., Lassus, M., ...

Background Tallimustine, a benzoyl nitrogen mustard derivative of the antiviral agent distamycin A, is a new alkylat-ing agent which binds to A-T rich regions of DNA in the minor groove producing...

Primary endocrine therapy for advanced breast cancer: To start with tamoxifen or with medroxyprogesterone acetate? (1993)

Castiglione-Gertsch, M., Pampallona, S., Varini, M., Cavalli, F., Brunner, K., Senn, H. J., ...

Background: The availability of compounds effective against metastatic disease and at the same time excellently tolerated even in long-term administration has determined the choice of tamoxifen as...

Oral ondansetron in the prophylaxis of nausea and vomiting induced by cyclophosphamide, methotrexate and 5-fluorouracil (CMF) in women with breast cancer. Results of a prospective, randomized, double-blind, placebo-controlled study (1993)

Buser, K. S., Joss, R. A., Piquet, D., Aapro, M. S., Cavalli, F., Haefliger, J. M., ...

Background: The combination of cyclophosphamide, methotrexate and 5-fluorouracil (CMF) is a widely used chemotherapy regimen in breast cancer patients. However, the control of nausea and vomiting...

Low-dose oral etoposide in epithelial cancer of the ovary (1993)

Marzola, M., Zucchetti, M., Colombo, N., Sessa, C., Pagani, O., D'Incalci, M., ...

Aims: To evaluate antitumour activity, toxicity, pharmacokinetics, and the pharmacodynamic relationship with neutropenia of low-dose oral etoposide (E) in patients (pts) with epithelial cancer of the...

Chronic oral etoposide in small-cell lung cancer: Clinical and pharmacokinetic results (1993)

Sessa, C., Zucchetti, M., Torri, V., Pagani, O., D'Incalci, M., Gentili, D., ...

Aims: To evaluate antitumour activity, toxicity, pharmacokinetics, and the pharmacodynamic relationship with neutropenia of chronic oral etoposide (E) in patients (pts) with small-cell lung cancer...

Childhood acute promyelocytic leukemia in Nicaragua (1993)

Corea, A.Malta, Espinoza, C. Pacheco, Cantù Rajnoldi, A., Conter, V., Lietti, G., Masera, G., ...

Background: The pediatric hematology-oncology service of the Managua 'La Mascota' Children's Hospital in Nicaragua began its activities in 1988. We report on unusual high incidence of acute...

Short report: Phase II trials of fosquidone (GR63178A) in carcinoma of the breast, head and neck, ovary and melanoma (1992)

Kaye, S. B., Wanders, J., Clavel, M., Verweij, J., Piccart, M. J., Smyth, J. F., ...

A total of 91 eligible patients with metastatic cancer have been treated in a series of phase II trials of the novel pentacyclic pyrroloquinone, fosquidone. Tumour types were breast (24), ovary (25),...

Feasibility of quality of life assessment in a randomized phase III trial of small cell lung cancer: -a lesson from the real world- (1992)

Hürny, C., Bernhard, J., Joss, R., Willems, Y., Cavalli, F., Kiser, J., ...

Between 1985 and 1990 the Swiss Group for Clinical Cancer Research (SAKK) for the first time assessed quality of life (QL) variables in 188 patients in a multicenter small-cell lung cancer trial that...

Original article: Sequential estrogen receptor determinations from primary breast cancer and at relapse: Prognostic and therapeutic relevance (1992)

Spataro, V., Price, K., Goldhirsch, A., Cavalli, F., Simoncini, E., Castiglione, M., ...

We retrospectively evaluated 401 selected patients who had estrogen receptor (ER) assays both at primary surgery and at relapse in an accessible site to determine the clinical relevance of the...

Original article: Phase II studies of 4'-iodo-4'-deoxydoxorubicin in advanced non-small cell lung, colon and breast cancers (1991)

Sessa, C., Calabresi, F., Cavalli, F, Cerny, T., Liati, P., Skovsgaard, T., ...

The new anthracycline analogue, 4'-iodo-4'-deoxydoxorubicin (I-DOX), was administered at 70 mg/m2as first chemotherapy in 61 patients with advanced NSCL (19), colon (20) and breast cancers (22)....

Original article: Phase I study of the combination of monthly carboplatin and weekly cisplatin (1991)

Sessa, C., Goldhirsch, A., Martinelli, G., Alerci, M., Imburgia, L., Cavalli, F.

Two cycles of the combination of carboplatin (C), given every 4 weeks with weekly doses of cisplatin (P), were administered on an outpatient basis to 28 previously untreated patients. One cycle...

Original article: CGS 16949A, a new aromatase inhibitor in the treatment of breast cancer -- A Phase I study (1990)

Beretta, K.R., Hoeffken, K., Kvinnsland, S., Trunet, P., Chaudri, A., Bhatnagar, A.S., ...

Forty-six postmenopausal women with either locally advanced or metastatic breast cancer were treated with the aromatase inhibitor CGS 16949A in three different daily doses (0.3 mg, 0.6 mg and 0.9 mg...

Effectiveness and low toxicity of hepatic artery infusion with fluorouracil and mitomycin for metastatic colorectal cancer confined to the liver (1990)

Borner, M., Laffer, U., Ludwig, C., Obrist, R., Metzger, U., Aeberhard, P., ...

The usefulness of hepatic artery infusion (HAI) with floxuridine is limited by the severe biliary and hepatic toxicity of floxuridine. This prompted the SAKK to evaluate the effectiveness, toxicity...

Phase II Study of Intravenous Menogaril in Patients With Advanced Breast Cancer (1988)

Sessa, C., Gundersen, S., Renard, J., Cavalli, F.

Menogaril was administered to 40 patients with advanced breast cancer who had not received anthracy-cline drugs previously. The drug was given iv as a 2-hour infusion, repeated every 4 weeks, at...

Concurrent or sequential use of cytotoxic chemotherapy and hormone treatment in advanced breast cancer: report of the Swiss Group for Clinical Cancer Research.

Cavalli, F, Beer, M, Martz, G, Jungi, W F, Alberto, P, Obrecht, J P, ...

In a trial of combined hormone treatment and cytotoxic chemotherapy 464 patients with advanced breast cancer were randomly allocated to either concurrent or sequential treatment. Cytotoxic drugs were...

Concurrent or sequential use of cytotoxic chemotherapy and hormone treatment in advanced breast cancer: report of the Swiss Group for Clinical Cancer Research.

Cavalli, F, Beer, M, Martz, G, Jungi, W F, Alberto, P, Obrecht, J P, ...

In a trial of combined hormone treatment and cytotoxic chemotherapy 464 patients with advanced breast cancer were randomly allocated to either concurrent or sequential treatment. Cytotoxic drugs were...

Detection of bcl-2/JH rearrangement in follicular and diffuse lymphoma: concordant results of peripheral blood and bone marrow analysis at diagnosis.

Yuan, R., Dowling, P., Zucca, E., Diggelmann, H., Cavalli, F.

The capacity to detect t(14;18) breakpoints in non-Hodgkin's lymphoma (NHL) peripheral blood and bone marrow was studied by DNA PCR. We studied 33 patients with follicular lymphoma (FL) (Working...

Estimation of the haematological toxicity of minor groove alkylators using tests on human cord blood cells.

Ghielmini, M., Bosshard, G., Capolongo, L., Geroni, M. C., Pesenti, E., Torri, V., ...

We evaluated the myelotoxicity and the anti-tumor potential of tallimustine, three of its analogues and carzelesin, with melphalan as reference substance. Tallimustine was tested by clonogenic assays...

Initial prognostic factors in small-cell lung cancer patients predicting quality of life during chemotherapy. Swiss Group for Clinical Cancer Research (SAKK).

Bernhard, J., Hürny, C., Bacchi, M., Joss, R. A., Cavalli, F., Senn, H. J., ...

The question of whether initial prognostic factors in small-cell lung cancer patients have a predictive value for patients' quality of life (QL) during chemotherapy is addressed in the context of a...

Clinical relevance of bcl-2(MBR)/J(H) rearrangement detected by polymerase chain reaction in the peripheral blood of patients with follicular lymphoma.

Bertoni, F., Bosshard, G., Roggero, E., Ceresa, E., Cavalli, F., Zucca, E.

We evaluated the prognostic role of peripheral blood polymerase chain reaction (PCR) assay for detection of the bcl-2(MBR)/J(H) rearrangement in 59 patients with follicular lymphoma (FL) treated at...

PTEN loss of expression predicts cetuximab efficacy in metastatic colorectal cancer patients

Frattini, M, Saletti, P, Romagnani, E, Martin, V, Molinari, F, Ghisletta, M, ...

To evaluate whether the epidermal growth factor receptor (EGFR), K-Ras and PTEN, all members of the EGFR signalling pathway, may affect the clinical response in cetuximab-treated metastatic...