Re: Pulmonary arterial hypertension in connective tissue diseases (2007)
Smith, V., De Pauw, M., Brusselle, G., Van Praet, J., De Keyser, F.
Geusens, P, Malaise, M, De Clerck, L, Raeman, F, ...
OBJECTIVE: To compare the effects of continuous and intermittent celecoxib treatment in patients with knee or hip osteoarthritis in flare. METHODS: In this 24-week, prospective, randomised,...
Luyten, F. P., GEUSENS, Piet, Malaise, M., De Clerck, L., Westhovens, R., Raeman, F., ...
Objective: To compare the effects of continuous and intermittent celecoxib treatment in patients with knee or hip osteoarthritis in flare. Methods: In this 24-week, prospective, randomised,...
Luyten, F. P., GEUSENS, Piet, Malaise, M., De Clerck, L., Westhovens, R., Raeman, F., ...
Objective: To compare the effects of continuous and intermittent celecoxib treatment in patients with knee or hip osteoarthritis in flare. Methods: In this 24-week, prospective, randomised,...
Interstitiële longafwijkingen bij reumatoide artritis (2007)
VAN SCHOOTE, E, VANWALLEGHEM, L, DE KEYSER, F, Joos, Guy, Brusselle, Guy
Vander Cruyssen, B., Nuytinck, L., Boullart, L., Elewaut, D., Waegeman, W., Van Thielen, M., ...
Objectives. We investigated the possible association of rheumatoid arthritis (RA) with single nucleotide polymorphisms (SNP) within the ficolin (FCN) genes. Two SNPs in the FCN1 gene, four SNPs in...
Dewint, P., Hoffman, I. E. A., Rogge, S., Joos, R., Union, A., Dehoorne, J., ...
Objectives. Anticitrullinated protein/peptide antibodies (ACPA) have an excellent diagnostic performance for rheumatoid arthritis (RA). Despite similarities between RA and polyarticular juvenile...
Peene, I, Union, A, Hulstaert, F, Meheus, L, ...
Cruyssen, B, Van Looy, S, Wyns, B, Westhovens, R, Durez, P, Malaise, M, ...
This study is based on an expanded access program in which 511 patients suffering from active refractory rheumatoid arthritis (RA) were treated with intravenous infusions of infliximab (3 mg/kg+...
Kruithof, E, Baeten, D, De Rycke, L, Vandooren, B, Foell, D, Roth, J, ...
At present only few biological data are available to indicate whether psoriatic arthritis (PsA) is part of the spondyloarthropathy (SpA) concept, whether it is a separate disease entity or a...
Baeten, D, Kruithof, E, De Rycke, L, Boots, A, Mielants, H, Veys, E, ...
Considering the relation between synovial inflammation and global disease activity in rheumatoid arthritis (RA) and the distinct but heterogeneous histology of spondyloarthropathy (SpA) synovitis,...
Dewint, P., Hoffman, I. E. A., Rogge, S., Joos, R., Union, A., Dehoorne, J., ...
Objectives. Anticitrullinated protein/peptide antibodies (ACPA) have an excellent diagnostic performance for rheumatoid arthritis (RA). Despite similarities between RA and polyarticular juvenile...
Chapuy-Regaud, S, Sebbag, M, Baeten, D, Clavel, C, De Keyser, F, Serre, G
No abstract available.
De Rycke, L, Baeten, D, Foell, D, Kruithof, E, Veys, EM, Roth, J, ...
No abstract available.
Cruyssen, B Vander, Peeters, H, Laukens, D, Coucke, P, Mielants, H, De Vos, M, ...
No abstract available.
The effect of infliximab on skin lesions in a patient with scleroderma (CREST) (2004)
De Rycke, L, Baeten, D, Mielants, H, De Keyser, F, Veys, EM
No abstract available.
Serum MRP8/MRP14 as a biomarker for inflammation in autoimmune arthritis (2004)
De Rycke, L, Baeten, D, Foell, D, Kruithof, E, Veys, EM, Roth, J, ...
No abstract available.
Poriau, S, De Keyser, F, GEUSENS, Piet
Locomotor Centrum, Sijsele Damme, Belgium. Inst Biomed Res, Diepenbeek, Belgium.
The lunar achilles as a screening tool for osteoporosis: Comparison with spine DXA (2004)
Poriau, S, De Keyser, F, GEUSENS, Piet
Locomotorisch Centrum, Sijsele Damme, Belgium. Inst Biomed Res, Diepenbeek, Belgium. Univ Hosp, Maastricht, Netherlands.
Poriau, S, De Keyser, F, GEUSENS, Piet
Locomotor Centrum, Sijsele Damme, Belgium. Inst Biomed Res, Diepenbeek, Belgium.
The lunar achilles as a screening tool for osteoporosis: Comparison with spine DXA (2004)
Poriau, S, De Keyser, F, GEUSENS, Piet
Locomotorisch Centrum, Sijsele Damme, Belgium. Inst Biomed Res, Diepenbeek, Belgium. Univ Hosp, Maastricht, Netherlands.
Demetter, P, Peeters, M, De Vos, M, Mielants, H, Veys, E M, ...
OBJECTIVES: To investigate whether anti-Saccharomyces cerevisiae antibodies (ASCA), a marker for Crohn's disease (CD), are present in spondyloarthropathies (SpA) and in the subgroups ankylosing...
Myeloid-related protein (MRP) 8 and MRP 14 in rheumatoid arthritis and spondyloarthropathy (2003)
De Rycke, L, Baeten, D, Foell, D, Veys, EM, De Keyser, F, Roth, J
No abstract available.
Local production of soluble CD163 in the spondyloarthropathic joint (2003)
Baeten, D, Møller, HJ, Delanghe, J, Veys, EM, Moestrup, SK, De Keyser, F
No abstract available.
Baeten, D, Kruithof, E, Hoffman, IEA, De Rycke, L, Vandooren, B, Veys, EM, ...
No abstract available.
Hoffman, I, Peene, I, Meheus, L, Bosschere, K De, Hulstaert, F, Huizinga, TWJ, ...
No abstract available.
De Rycke, L, Kruithof, E, Van Damme, N, Hoffman, IEA, Veys, EM, ...
No abstract available.
Baeten, D, Steenbakkers, PGA, Rovers, E, Veys, EM, Rijnders, AMW, Meijerink, J, ...
No abstract available.
Baeten, D, Steenbakkers, P, Boots, A, Veys, EM, De Keyser, F
No abstract available.
Chapuy-Regaud, S, Sebbag, M, Nachat, R, Baeten, D, Foulquier, V, Simon, M, ...
No abstract available.
De Keyser, F, Peeters, H, Marichal, D, Hoffman, I, ...
No abstract available.
Baeten, D, Wyns, B, Hoffman, I, Sette, S, Boullart, L, De Keyser, F
No abstract available.
Meheus, L, Humbel, RL, Conrad, K, Steiner, G, Moereels, H, ...
Objective. To identify immunodominant epitopes in natural filaggrin that are reactive with antifilaggrin autoantibodies (AFA) in the sera of patients with rheumatoid arthritis (RA) and to explore...
Hoffman, IEA, Peene, I, Veys, EM, De Keyser, F
No abstract available.
Van Damme, N, De Rycke, L, Kruithof, E, Hoffman, IEA, Veys, EM, De Keyser, F
No abstract available.
De Rycke, LEB, Van Damme, N, Kruithof, E, Hoffman, IEA, Veys, EM, De Keyser, F
No abstract available.
Vanderborght, A, De Keyser, F, De Backer, M, Malaise, M, Baeten, D, ...
Objective. To study T cell receptor (TCR) repertoire changes in synovial membrane over a 16 week period in patients with early rheumatoid arthritis (RA); and to study the influence of cyclosporin A...
Vanderborght, A, De Keyser, F, De Backer, M, Malaise, M, Baeten, D, ...
Objective. To study T cell receptor (TCR) repertoire changes in synovial membrane over a 16 week period in patients with early rheumatoid arthritis (RA); and to study the influence of cyclosporin A...
De Keyser, F, Geusens, P, De Backer, Manu; U0039058, Malaise, M, Baeten, D, ...
Objective. To study T cell receptor (TCR) repertoire changes in synovial membrane over a 16 week period in patients with early rheumatoid arthritis (RA); and to study the influence of cyclosporin A...
Baeten, D, Demetter, P, Cuvelier, C, Kruithof, E, Van Damme, N, De Vos, M, ...
No abstract available.
Anti-saccharomyces cerevisiae antibodies in ankylosing spondylitis (2001)
Hoffman, IEA, Veys, EM, Peeters, M, De Vos, M, Mielants, H, De Keyser, F
Occurrence of scleroderma in monozygotic twins. (2000)
DE KEYSER, F, PEENE, I, JOOS, R, Naeyaert, Jean, MESSIAEN, L, VEYS, EM
De Vos, M, De Keyser, F, Baeten, D, Van Damme, N, ...
Effects of chemical agents and enzymes on lymphocyte surface markers. (1999)
VAN DAMME, N, BAETEN, D, DE VOS, M, Demetter, Pieter, ELEWAUT, D, MIELANTS, H, ...
The pathophysiology of lupus erythematosus (1998)
De Keyser, F, Praet, M, Naeyaert, J M
Systemic lupus erythematosus disseminatus in addition to the more restricted, lupus-like syndromes, is the consequence of an attack by the immune system on the cellular and nuclear structures of the...
Elewaut, D., De Keyser, F., De Wever, N., Baeten, D., Van Damme, N., Verbruggen, G., ...
OBJECTIVES—(1)To analyse the in situ expression of adhesion molecules in rheumatoid nodules. (2) To compare the endothelial expression of adhesion molecules in synovial tissue and subcutaneous...
Vincent, C., De Keyser, F., Masson-Bessiere, C., Sebbag, M., Veys, E., Serre, G.
OBJECTIVE—Antiperinuclear factor (APF), "antikeratin antibodies" ("AKA"), and antibodies to human epidermis filaggrin (AFA), are highly specific serological markers of rheumatoid arthritis (RA),...
Baeten, D, Demetter, P, Cuvelier, C, Kruithof, E, Van Damme, N, ...
OBJECTIVES—To compare the macroscopic and microscopic characteristics of synovial tissue in rheumatoid arthritis (RA), spondyloarthropathy (SpA), and osteoarthritis (OA) after exclusion of possible...
Demetter, P, Baeten, D, De Keyser, F, De Vos, M, Van Damme, N, Verbruggen, G, ...
OBJECTIVE—Previously an upregulation of E-cadherin and its associated molecules α-catenin, β-catenin and plakoglobin has been demonstrated in clinically overt inflammatory bowel disease (IBD)....
Kruithof, E., Baeten, D., De Keyser, F., Mielants, H., Veys, E.
OBJECTIVE—To evaluate the efficacy and safety of a loading dose regimen of three intravenous infusions with infliximab in patients with active spondyloarthropathy. METHODS—A monocentre,...
Peene, I, Meheus, L, Veys, E, De Keyser, F
OBJECTIVE—To provide data on (a) the probability of detecting antinuclear antibodies (ANA) in a large and consecutive cohort of serum samples referred for ANA testing and (b) the probability of...
Van Damme, N, De Vos, M, Baeten, D, Demetter, P, Mielants, H, Verbruggen, G, ...
OBJECTIVE—To quantify the fraction of gut mucosal lymphocytes expressing the T helper type 1 (Th1) cytokines, interferon γ (IFNγ) and interleukin (IL)2, and the Th2 cytokines, IL4 and IL10, at...
Impaired Th1 cytokine production in spondyloarthropathy is restored by anti-TNFα
Baeten, D, Van Damme, N, Kruithof, E, De Vos, M, Mielants, H, ...
OBJECTIVES—To evaluate the effect of anti-TNFα on the Th1 and Th2 cytokines in patients with spondyloarthropathy (SpA). METHODS—Peripheral blood mononuclear cells (PBMC) were obtained from...
Anti-Ro52 reactivity is an independent and additional serum marker in connective tissue disease
Peene, I, Meheus, L, De Keyser, S, Humbel, R, Veys, E, De Keyser, F
Methods: Over a two year period, 1727 consecutive antinuclear antibody (ANA) positive serum samples were analysed in parallel by double immunodiffusion with thymus/spleen nuclear extract and by line...
Peene, I, Meheus, L, Veys, E, De Keyser, F
Objective: To determine the diagnostic distribution in a consecutive anti-SSA and/or anti-SSB positive population.
Kruithof, E, Baeten, D, Herssens, A, De Keyser, F, Mielants, H, ...
Background: In a pilot study, the anti-tumour necrosis factor α monoclonal antibody, infliximab, induced a rapid and significant improvement in global, peripheral, and axial disease manifestations...
Tenosynovitis with acute onset: unexpected giant cell tumour of the tendon sheath
Kruithof, E, Baeten, D, Dierckxsens, P, Veys, E, De Keyser, F
Hoffman, I, Demetter, P, Peeters, M, De Vos, M, Mielants, H, Veys, E, ...
Objectives: To investigate whether anti-Saccharomyces cerevisiae antibodies (ASCA), a marker for Crohn's disease (CD), are present in spondyloarthropathies (SpA) and in the subgroups ankylosing...
Baeten, D, Kruithof, E, Herssens, A, Mielants, H, ...
Background: Recent studies with infliximab indicate the therapeutic potential of tumour necrosis factor α blockade in spondyloarthropathy (SpA). Because defective host defence is implicated in the...
Case Number 29: Ochronosis: synovial histopathological characteristics
Kruithof, E, Baeten, D, Veys, E, De Keyser, F, Suykens, S, De Wilde, L, ...
Baeten, D, De Keyser, F, Veys, E, Theate, Y, Houssiau, F, Durez, P
Background: It has been suggested that the immunopathology of rheumatoid nodules parallels that of inflamed synovium in rheumatoid arthritis (RA).
Rihl, M, Baeten, D, Seta, N, Gu, J, De Keyser, F, Veys, E, ...
Objectives: To validate the use of cDNA based microarray on synovial biopsies by analysing the experimental variability due to amplification of RNA, reproducibility of the assay, heterogeneity of the...
Cruyssen, B Vander, Peeters, H, Hoffman, I E A, Laukens, D, Coucke, P, Marichal, D, ...
Carriage of CARD15 gene polymorphisms and the serological marker anti-Saccharomyces cerevisiae antibodies (ASCA) are two markers for Crohn's disease (CD). Similar phenotypes have been associated with...
Van Damme, N, De Keyser, F, Demetter, P, Baeten, D, Mielants, H, Verbruggen, G, ...
T lymphocytes and their cytokines have an important role in the regulation of immune responses in the gut and in the pathogenesis of intestinal inflammation such as in Crohn's disease. The aim of...
Hoffman, I, Peene, I, Meheus, L, Huizinga, T, Cebecauer, L, Isenberg, D, ...
Methods: A consecutive cohort of 289 patients with SLE was included; 235 fulfilled ACR criteria for SLE and were further analysed. ANA profiles were determined by line immunoassay and by indirect...
Peeters, H, Vander, C, Laukens, D, Coucke, P, Marichal, D, ...
Background: Sacroiliitis is a common extraintestinal manifestation of Crohn's disease but its association with the HLA-B27 phenotype is less evident. Polymorphisms in the CARD15 gene have been linked...
De Rycke, L, Peene, I, Hoffman, I, Kruithof, E, Union, A, Meheus, L, ...
Background: Autoantibodies such as rheumatoid factor (RF) and anticitrullinated protein antibodies can be detected in rheumatoid arthritis (RA) sera.
Demetter, P, De Vos, M, Van Huysse, J A, Baeten, D, Ferdinande, L, Peeters, H, ...
Objective: To investigate macrophages and other antigen presenting cells in gut mucosa from patients with SpA and Crohn's disease, given the relationship between both entities.
De Rycke, L, Verhelst, X, Kruithof, E, Hoffman, I, Veys, E, ...
Patients and methods: 62 patients with refractory RA were treated with infliximab combined with methotrexate. At baseline and week 30, serum samples were tested for IgM RF by two agglutination...
Hoffman, I, Peene, I, Cebecauer, L, Isenberg, D, Huizinga, T, Union, A, ...
Kruithof, E, Baeten, D, Mielants, H, Veys, E, De Keyser, F
Objective: To confirm and extend the immunopathological evidence of effects of infliximab on the synovium in active spondyloarthropathy.
Trisomy 3 mosaicism in a patient with Bartter syndrome.
De Keyser, F, Matthys, E, De Paepe, A, Verschraegen-Spae, M R, Matton, M
Laukens, D, Peeters, H, Marichal, D, Vander, C, Mielants, H, Elewaut, D, ...
Background: The association between spondyloarthropathy and Crohn's disease is well known. A risk for evolution to Crohn's disease has already been shown in the subgroup of patients with...
Anti-citrullinated peptide antibodies may occur in patients with psoriatic arthritis
Vander, C, Hoffman, I, Zmierczak, H, Kruithof, E, De Rycke, L, ...
Background: Anti-cyclic citrullinated peptide (anti-CCP) antibodies are considered highly specific markers of rheumatoid arthritis. Despite the high specificity of the test, anti-CCP antibodies have...
Carron, P, Hoffman, I, De Rycke, L, Peene, I, Veys, E, De Keyser, F, ...
Cantaert, T, Coucke, P, De Rycke, L, Veys, E, De Keyser, F, Baeten, D
Background: Haplotypes of PADI4, encoding for a citrullinating enzyme, were associated with rheumatoid arthritis in a Japanese population. It was suggested they were related to the presence of...
Rihl, M, Kruithof, E, Barthel, C, De Keyser, F, Veys, E, Zeidler, H, ...
Objective: To investigate whether expression of the four members of the neurotrophin (NT) family and their four corresponding receptors is related to synovial inflammation in patients with...
Small vessel vasculitis in a patient with sarcoidosis. Clin. Rheumatol., 13, 401, 1994.
SCHATTEMAN, L, DE KEYSER, F, Praet, Marleen, KIPS, J, Naeyaert, Jean, VEYS, E
Clinical and Experimental Rheumatology, 1996: 14, pp.665-668, 2 tab.
GYSELBRECHT, L, DE KEYSER, F, ONGENAE, K, Naeyaert, Jean, Praet, Marleen, VEYS, EM
Bone and joint diseases in inflammatory bowel disease. Aliment Pharmacol Ther,12,1998,397-404.
DE VOS, M, DE KEYSER, F, MIELANTS, H, Cuvelier, Claude, VEYS, E
Leflunomide and methotrexate combination therapy in daily clinical practice
Dendooven, A, De Rycke, L, Verhelst, X, Mielants, H, Veys, E M, De Keyser, F