An embryonic specific repressor element located 3' to the Ay-globin gene influences transcription of the human beta globin locus in transgenic mice. (2004)
Katsantoni, E.,
De Krom, M.,
Imam, A.,
Grosveld, F.G.,
Anagnou, N.,
...
Multiple interactions between regulatory regions are required to stabilise an Active Chromatin Hub. (2004)
Patrinos, G.,
De Krom, M.,
De Boer, E.,
Langeveld, A.,
Strouboulis, J.,
Imam, A.,
...
GATA-1 forms distinct activating and repressive complexes in erythroid cells. (2004)
Rodriguez, P.,
Bonte, E.,
Krijgsveld, J.,
Kolodziej, K.,
Guyot, B.,
Heck, A.J.R.,
...
Transcription factor GATA3 regulates extension and pathfinding of the Wolffian duct. (2004)
Pata, I.,
Jakobson, M.,
Meier, R.,
Lulla, P.,
Körner, J.,
Grosveld, F.G.,
...
The active spatial organisation of the β-globin locus requires the transcription factor EKLF (2004)
Drissen, R.,
Palstra, R.J.,
Gillemans, N.,
Splinter, E.,
Grosveld, F.G.,
Philipsen, J.,
...
Homotypic signalling regulates Gata1 activity in the erythroblastic island. (2004)
Gutierrez, L.,
Lindeboom, F.,
Langeveld, A.,
Grosveld, F.G.,
Philipsen, J.,
Whyatt, D.
Cell autonomy of the mouse claw paw mutation. (2004)
Darbas, A.,
Jaegle, M.,
Walbeehm, E.,
Driegen, S.,
Broos, L.,
...
Conformational changes in CLIP-170 regulate its binding to microtubules and dynactin localization (2004)
Lansbergen, G.,
Hoogenraad, C.C.,
Goodson, H.V.,
Lemaitre, R.P.,
Akhmanova, A.,
Drechsel, D.N.,
...
Cytoplasmic linker protein (CLIP)-170, CLIP-115, and the dynactin subunit p150(Glued) are structurally related proteins, which associate specifically with the ends of growing microtubules (MTs)....
Transposition of the Drosophila hydei Minos transposon in the mouse germ line. (2003)
Drabek, D.,
Zagoraiou, L.,
De Wit, T.,
Langeveld, A.,
Roumpaki, C.,
Mamalaki, C.,
...
A functional and comparative analysis of globin loci in pufferfish and man. (2003)
Gillemans, N.,
McMorrow, T.,
Tewari, R.,
Wai, W.K.,
Burgtorf, C.,
Drabek, D.,
...
Efficient biotinylation and single-step purification of tagged transcription factors in mammalian cells and transgenic mice. (2003)
Rodriguez, P.,
Bonte, E.,
Krijgsveld, J.,
Katsantoni, E.,
Heck, A.,
...
Impaired hematopoiesis in mice lacking the transcription factor Sp3. (2003)
Bouwman, P.,
Ling, K.W.,
Middendorp, S.,
Suske, G.,
Grosveld, F.G.,
...
Bicaudal D induces selective dynein-mediated microtubule minus end-directed transport. (2003)
Hoogenraad, C.C.,
Wulf, P.,
Schiefermeier, N.,
Stepanova, T.,
Galjart, N.,
Small, J.V.,
...
Characterization of HS5 of the human β-globin Locus Control Region: a developmental stage-specific border in erythroid cells. (2003)
Wai, A.,
Gillemans, N.,
Raguz-Bolognesi, S.,
Pruzina, S.,
Zafarana, G.,
Meijer, D.,
...
Intracellularly expressed single chain antibody prevents the production of porcine retroviruses. (2003)
Dekker, S.,
Toussaint, W.,
Panayotou, G.,
De Wit, T.,
Visser, P.,
Grosveld, F.G.,
...
The beta-globin nuclear compartment in development and erythroid differentiation. (2003)
Palstra, R.J.,
Tolhuis, B.,
Splinter, E.,
Nijmeijer, R.,
Grosveld, F.G.,
De Laat, W.
Persistent gamma-globin expression in adult transgenic mice by HPFH-2, HPFH-3 and HPFH-6 breakpoint sequences. (2003)
Katsantoni, E.,
Langeveld, A.,
Wai, A.W.,
Drabek, D.,
Grosveld, F.G.,
Anagnou, N.P.,
...
The POU proteins Brn-2 and Oct-6 share important functions in Schwann cell development. (2003)
Jaegle, M.,
Ghazvini, M.,
Mandemakers, W.,
Piirsoo, M.,
Driegen, S.,
Levavasseur, F.,
...
Visualization of microtubule growth in cultured neurons via the use of EB3-GFP (end-binding protein 3-green fluorescent protein). (2003)
Stepanova, T.,
Slemmer, J.,
Hoogenraad, C.C.,
Lansbergen, G.,
Dortland, B.,
De Zeeuw, C.I.,
...
A tissue-specific knockout reveals that Gata1 is not essential for Sertoli cell function in the mouse. (2003)
Lindeboom, F.,
Gillemans, N.,
Karis, A.,
Jaegle, M.,
Meijer, D.,
Grosveld, F.G.,
...
Functional and comparative analysis of globin loci in pufferfish and humans (2003)
Gillemans, N.,
Tan-Un, K.,
Philipsen, S.,
Grosveld, F.G.,
McMorrow, T.,
Tewari, R.,
...
To further our understanding of the regulation of vertebrate globin loci, we have isolated cosmids containing alpha- and beta-globin genes from the pufferfish Fugu rubripes. By DNA fluorescence in...
Impaired hematopoiesis in mice lacking the transcription factor Sp3 (2003)
Loo, P.F. Van,
Bouwman, P.,
Ling, K.W.,
Middendorp, S.,
Suske, G.,
Grosveld, F.G.,
...
As the zinc-finger transcription factor specificity protein 3 (Sp3) has been implicated in the regulation of many hematopoietic-specific genes, we analyzed the role of Sp3 in hematopoiesis. At...
LCR-mediated, long-term tissue-specific gene expression within replicating episomal plasmid vectors. (2002)
Chow, C.,
Athanassiadou, A.,
Raguz, S.,
Psiouri, L.,
Harland, L.,
Malik, M.,
...
Bicaudal-D regulates COPI-independent Golgi-ER transport by recruiting the dynein-dynactin motor complex (2002)
Matanis, T.,
Akhmanova, A.,
Wulf, P.,
Del Nery, E.,
Weide, T.,
Stepanova, T.,
...
Reduction of blood pressure, plasma cholesterol and atherosclerosis by elevated endothelial nitric oxide. (2002)
De Waard, M.,
Van Deel, E.,
Mees, B.,
Kutryk, M.,
Van Aken, T.,
...
Targeted mutation of Cyln2, in the Williams Syndrome critical region, links CLIP-115 haploinsufficiency to neurodevelopmental abnormalities (2002)
Hoogenraad, C.,
Koekkoek, B.,
Akhmanova, A.,
Krugers, H.,
Dortland, B.,
Miedema, M.,
...
A cell type-specific allele of the POU gene Oct-6 reveals Schwann cell autonomous function in nerve development and regeneration. (2002)
Ghazvini, M.,
Mandemakers, W.,
Jaegle, M.,
Piirsoo, M.,
Driegen, S.,
Koutsourakis, M.,
...
Enforced expression of GATA-3 during T cell development inhibits maturation of CD8 single-positive cells and induces thymic lymphoma in transgenic mice. (2001)
Nawijn, M.C.,
Ferreira, R.,
Dingjan, G.M.,
Kahre, O.,
Drabek, D.,
Karis, A.,
...
Enforced expression of GATA-3 in transgenic mice inhibits Th1-differentiation and induces the formation of a T1/ST2-expressing Th2 committed T cell compartment in vivo. (2001)
Nawijn, M.C.,
Dingjan, G.M.,
Ferreira, R.,
Lambrecht, B.N.,
Karis, A.,
Grosveld, F.G.,
...
Enforced expression of GATA-3 during T cell development inhibits maturation of CD8 single positive cells and induces thymic lymphoma in transgenic mice. (2001)
Nawijn, M.C.,
Ferreira, R.,
Dingjan, G.M.,
Kahre, O.,
Drabek, D.,
Karis, A.,
...
Bruton's tyrosine kinase regulates the activation of gene rearrangements at the λ light chain locus in precursor B cells in the mouse. (2001)
Dingjan, G.M.,
Middendorp, S.,
Dahlenborg, K.,
Maas, A.,
Grosveld, F.G.,
Hendriks, R.W.
Clasps are CLIP-115 and -170 associating proteins involved in the regional regulation of microtubule dynamics in motile fibroblasts (2001)
Akhmanova, A.,
Hoogenraad, C.,
Drabek, K.,
Stepanova, T.,
Dortland, B.,
Verkerk, T.,
...
Transcription factor GATA-3 alters pathway selection of olivocochlear neuron and affects morphogenesis of the ear. (2001)
Karis, A,
Pata, I.,
Doorninck, J.H. Van,
Grosveld, F.G.,
Zeeuw, C.I. De,
Caprona, D. De,
...
The transcription factor GATA6 is essential for branching morphogenesis and epithelial cell differentiation during fetal pulmonary development. (2001)
Keijzer, R.,
Van Tuyl, M.,
Meijers, J.H.C.,
Post, M.,
Tibboel, D.,
Grosveld, F.G.,
...
Developmental regulation of DNA replication timing at the human β globin locus. (2001)
Simon, I.,
Tenzen, T.,
Mostoslavsky, R.,
Fibach, E.,
Lande, L.,
Milot, E.,
...
Branching and differentiation defects in pulmonary epithelium with elevated GATA6 expression. (2001)
Koutsourakis, M.,
Keijzer, R.,
Visser, P.,
Post, M.,
Tibboel, D.,
Grosveld, F.G.
In vivo transposition of Minos, a Drosophila mobile element, in mammalian tissues (2001)
Zagoraiou, L.,
Drabek, D.,
Klinakis, A.G.,
Langeveld, A.,
Alexaki, S.,
Mamalaki, C.,
...
Baculovirus infection of nondividing mammalian cells: mechanisms of entry nuclear transport of capsids. (2001)
Van Loo, N.D.,
Fortunati, E.,
Ehlert, E.,
Rabelink, M.,
Grosveld, F.G.,
Scholte, B.J.
The role of the -50 region of the human γ-globin gene in switching. (2001)
Ristaldi, M.S.,
Drabek, D.,
Gribnau, J.,
Poddie, D.,
Yannoutsos, N.,
Cao, A.,
...
Mammalian Golgi-associated Bicaudal-D2 functions in the dynein-dynactin pathway by interacting with these complexes. (2001)
Hoogenraad, C.C.,
Akhmanova, A.,
Howell, S.A.,
Dortland, B.R.,
De Zeeuw, C.I.,
Willemsen, R.,
...
Xenotransplantatie. (2001)
Schaapherder, A.F.M.,
Terpstra, O.T.,
Marquet, R.L.,
IJzermans, J.N.M.,
Bouwman, E.,
Boer, G.J.,
...
Transcriptional activation of the β globin locus and modulation of position effect variegation by transcription factors and chromatin modifiers. (2000)
McMorrow, T.,
Trimborn, T.,
Van Lohuizen, M.,
Jenuwein, T.,
Djabali, M.,
...
An intrinsic but cell-nonautonomous defect in GATA-1 overexpressing mouse erythroid cells. (2000)
Whyatt, D.,
Lindeboom, F.,
Karis, A.,
Milot, E.,
Hendriks, R.,
De Bruijn, M.,
...
Modification of human β-globin locus PAC clones by homologous recombination in Escherichia coli. (2000)
Imam, A.M.A.,
Patrinos, G.,
De Krom, M.,
Bottardi, S.,
Janssens, R.J.,
Katsantoni, E.,
...
Transcription factor Sp3 is essential for post-natal survival and late tooth development. (2000)
Bouwman, P.,
Göllner, H.,
Elsässer, H.P.,
Eckhoff, G.,
Karis, A.,
Grosveld, F.G.,
...
Gata3 loss leads to embryonic lethality due to noradrenaline deficiency of the sympathetic nervous system. (2000)
Lim, K.C.,
Lakshmanan, G.,
Crawford, S.E.,
Gu, Y.,
Grosveld, F.G.,
Engel, J.D.
A distal Schwann cell-specific enhancer mediates axonal regulation of the Oct-6 transcription factor during peripheral nerve development and regeneration. (2000)
Mandemakers, W.,
Zwart, R.,
Jaegle, M.,
Walbeehm, E.,
Visser, P.,
Grosveld, F.G.,
...
Human plasma phospholipid transfer protein increases the antiatherogenic potential of high density lipoproteins in transgenic mice. (2000)
Van Haperen, R.,
Van Tol, A.,
Vermeulen, P.,
Jauhiainen, M.,
Van Gent, T.,
...
A multi-domain protein for beta1 integrin-targeted DNA delivery. (2000)
Fortunati, E.,
Ehlert, E.,
Van Loo, N.D.,
Wyman, C.,
Eble, J.A.,
Grosveld, F.G.,
...