F. Hiepe

Publication List Details

Period

2001 - 2007

Number

35

Co-Authors

Effect of dsDNA binding to SmD-derived peptides on clinical accuracy in the diagnosis of systemic lupus erythematosus (2007)

Mahler, Michael, Waka, Aderajew, Hiepe, F, Fritzler, Marvin J

Abstract Systemic lupus erythematosus is characterized by antibodies to a variety of intracellular self-antigens, such as dsDNA and Sm, and these serve as hallmarks in the diagnosis of systemic...

A novel epitope on the C-terminus of SmD1 is recognized by the majority of sera from patients with systemic lupus erythematosus.

Riemekasten, G, Marell, J, Trebeljahr, G, Klein, R, Hausdorf, G, Häupl, T, ...

The SmD1 protein is a specific target for the autoantibody response in SLE. To further analyze this reactivity epitope, mapping was performed with cellulose-bound 13-mer peptides overlapping 10 amino...

Antigen-driven clonal proliferation of B cells within the target tissue of an autoimmune disease. The salivary glands of patients with Sjögren's syndrome.

Stott, D I, Hiepe, F, Hummel, M, Steinhauser, G, Berek, C

Structures resembling germinal centers are seen in the salivary glands of patients with Sjögren's syndrome, but it is not known whether the microenvironment of these cell clusters is sufficient for...

A novel epitope on the C-terminus of SmD1 is recognized by the majority of sera from patients with systemic lupus erythematosus.

Riemekasten, G, Marell, J, Trebeljahr, G, Klein, R, Hausdorf, G, Häupl, T, ...

The SmD1 protein is a specific target for the autoantibody response in SLE. To further analyze this reactivity epitope, mapping was performed with cellulose-bound 13-mer peptides overlapping 10 amino...

Antigen-driven clonal proliferation of B cells within the target tissue of an autoimmune disease. The salivary glands of patients with Sjögren's syndrome.

Stott, D I, Hiepe, F, Hummel, M, Steinhauser, G, Berek, C

Structures resembling germinal centers are seen in the salivary glands of patients with Sjögren's syndrome, but it is not known whether the microenvironment of these cell clusters is sufficient for...

Enhanced membrane expression of the 52 kDa Ro(SS-A) and La(SS-B) antigens by human keratinocytes induced by TNF alpha.

Dörner, T, Hucko, M, Mayet, W J, Trefzer, U, Burmester, G R, Hiepe, F

OBJECTIVE--To investigate the membrane expression of the 52 kDa Ro(SS-A) and La(SS-B) antigens in human keratinocytes under the influence of an important mediator of inflammation, TNF alpha....

Monocytes from systemic lupus erythematous patients are severely altered in phenotype and lineage flexibility

Steinbach, F., Henke, F., Krause, B., Thiele, B., Burmester, G., Hiepe, F.

OBJECTIVE—Cells of the myeloid lineage comprise a very heterogeneous population with many phenotypes and functional activities including macrophages and dendritic cells. To investigate the status,...

Prolactin enhances the in vitro production of IgG in peripheral blood mononuclear cells from patients with systemic lupus erythematosus but not from healthy controls

Jacobi, A, Rohde, W, Volk, H, Dorner, T, Burmester, G, Hiepe, F

OBJECTIVES—Recent evidence suggests that prolactin (PRL) plays a part in the pathogenesis of systemic lupus erythematosus (SLE). Because B cell hyperreactivity and autoantibodies are characteristic...

Phase I/II trial of autologous stem cell transplantation in systemic sclerosis: procedure related mortality and impact on skin disease

Binks, M, Passweg, J, Furst, D, McSweeney, P, Sullivan, K, Besenthal, C, ...

BACKGROUND—Systemic sclerosis (SSc, scleroderma) in either its diffuse or limited skin forms has a high mortality when vital organs are affected. No treatment has been shown to influence the...

Rapid detection of autoantibodies to dsDNA with the particle gel immunoassay (ID-PaGIA)

Seltsam, A, Schwind, P, Abraham, K, Hiepe, F, Cygan, S, Aebischer, I, ...

Patients and methods: Serum samples were collected from 40 unselected healthy blood donors and 200 patients with systemic lupus erythematosus (SLE) or a positive antinuclear antibody screen, or both....

T cell reactivity against the SmD183–119 C terminal peptide in patients with systemic lupus erythematosus

Riemekasten, G, Weiss, C, Schneider, S, Thiel, A, Bruns, A, Schumann, F, ...

Background: The SmD183–119 peptide is a major target of the B cell response in patients with systemic lupus erythematosus (SLE).

Perturbations of peripheral B lymphocyte homoeostasis in children with systemic lupus erythematosus

Odendahl, M, Keitzer, R, Wahn, U, Hiepe, F, Radbruch, A, Dorner, T, ...

Objective: To investigate the distribution of peripheral B cell subpopulations of children with active and inactive systemic lupus erythematosus (SLE) compared with healthy controls.

Anti-phospholipid antibodies and CD5+ B cells in HIV infection

Grünewald, T, Burmester, G-R, Schüler-Maué, W, Hiepe, F, Buttgereit, F

This cross-sectional study evaluates the correlation between anti-phospholipid antibodies and CD5+ B cells in 110 patients infected with HIV-1. There were 89.1% of the patients who had IgG antibodies...

Autologous stem cell transplantation in the treatment of systemic sclerosis: report from the EBMT/EULAR Registry

Farge, D, Passweg, J, Van Laar, J M, Marjanovic, Z, Besenthal, C, Finke, J, ...

Objective: To analyse the durability of the responses after haematopoietic stem cell transplantation (HSCT) for severe systemic sclerosis (SSc) and determine whether the high transplant related...

Antigen-driven clonal proliferation of B cells within the target tissue of an autoimmune disease: the salivary glands of patients with Sjögren's syndrome

Stott, D.I., Hiepe, F., Hummel, M., Steinhauser, G., Berek, C.

Structures resembling germinal centers are seen in the salivary glands of patients with Sjögren's syndrome, but it is not known whether the microenvironment of these cell clusters is sufficient for...

Effect of dsDNA binding to SmD-derived peptides on clinical accuracy in the diagnosis of systemic lupus erythematosus

Mahler, Michael, Waka, Aderajew, Hiepe, F, Fritzler, Marvin J

Systemic lupus erythematosus is characterized by antibodies to a variety of intracellular self-antigens, such as dsDNA and Sm, and these serve as hallmarks in the diagnosis of systemic autoimmune...

Antigen-driven clonal proliferation of B cells within the target tissue of an autoimmune disease: the salivary glands of patients with Sjögren's syndrome

Stott, D.I., Hiepe, F., Hummel, M., Steinhauser, G., Berek, C.

Structures resembling germinal centers are seen in the salivary glands of patients with Sjögren's syndrome, but it is not known whether the microenvironment of these cell clusters is sufficient for...