Activation of c-myc and c-K-ras oncogenes in primary rat tumors induced by ionizing radiation.
Sawey, M J, Hood, A T, Burns, F J, Garte, S J
An activated K-ras oncogene was detected by transfection in NIH 3T3 cells and by Southern blot analysis in 6 of 12 rat skin tumors induced by ionizing radiation. The DNA from 10 of the 12 tumors also...
Multiple stages in radiation carcinogenesis of rat skin.
Burns, F J, Albert, R E, Garte, S J
Epithelial cell cancers are induced in rat skin by ionizing radiation in a manner that is consistent with the dual action (i.e., two alterations) hypothesis of radiation effects on DNA. This...
Oncogenes and radiation carcinogenesis.
Current research indicates a role for several oncogenes in radiation-induced carcinogenesis in vivo and cell transformation in vitro. Certain oncogenes are probably also involved in some cases of...
Activation of c-myc and c-K-ras oncogenes in primary rat tumors induced by ionizing radiation.
Sawey, M J, Hood, A T, Burns, F J, Garte, S J
An activated K-ras oncogene was detected by transfection in NIH 3T3 cells and by Southern blot analysis in 6 of 12 rat skin tumors induced by ionizing radiation. The DNA from 10 of the 12 tumors also...
Multiple stages in radiation carcinogenesis of rat skin.
Burns, F J, Albert, R E, Garte, S J
Epithelial cell cancers are induced in rat skin by ionizing radiation in a manner that is consistent with the dual action (i.e., two alterations) hypothesis of radiation effects on DNA. This...
Oncogenes and radiation carcinogenesis.
Current research indicates a role for several oncogenes in radiation-induced carcinogenesis in vivo and cell transformation in vitro. Certain oncogenes are probably also involved in some cases of...
Oxidative stress suppresses transcription factor activities in stimulated lymphocytes
Flescher, E, Tripoli, H, Salnikow, K, Burns, F J
Effects of oxidative stress on stimulation-dependent signal transduction, leading to IL-2 expression, were studied. Purified quiescent human blood T lymphocytes were subjected to: (i) acute exposure...