Van Roon, J. A G, Verhoef, C., Van Roy, J. L A M, Gmelig-Meyling, F., Huber-Bruning, O., Lafeber, F., ...
Objectives—To compare peripheral type 1 (T1) and type 2 (T2) T cell activities in rheumatoid arthritis (RA) patients with that found for osteoarthritic (OA) patients and healthy controls and to...
Mutual antagonism of rheumatoid arthritis and hay fever; a role for type 1/type 2 T cell balance
Verhoef, C., Van Roon, J. A G, Vianen, M., Bruijnzeel-Koomen, C., Lafeber, F., Bijlsma, J.
OBJECTIVES—The balance between interferon γ(IFNγ) and interleukin 4 (IL4) producing T cells (T1 and T2 cells) seems to be of importance in many (auto)immune disorders. In general, T1 cell...
Verhoef, C., Van Roon, J. A G, Vianen, M., Lafeber, F., Bijlsma, J.
OBJECTIVES—The influence of dexamethasone on interleukin 10 (IL10) production and the type 1 (T1)/type 2 (T2) T cell balance found in rheumatoid arthritis (RA) was...
Van Roon, J A G, Glaudemans, K, Bijlsma, J, Lafeber, F
Background: A large number of activated T cells are found in the joints of patients with rheumatoid arthritis (RA). Interleukin 7 (IL7), a T cell growth factor and a regulator of Th1 and Th2 cytokine...
Van Roon, J A G, Bijlsma, J, Van De Winkel, J G J, Lafeber, F
Background: Monocytes/macrophages have an important and versatile role in joint inflammation and destruction in rheumatoid arthritis (RA).