Pommier, Y, Kohlhagen, G, Kohn, K W, Leteurtre, F, Wani, M C, Wall, M E
DNA topoisomerase I (top1) is a ubiquitous nuclear enzyme. It is specifically inhibited by camptothecin, a natural product derived from the bark of the tree Camptotheca acuminata. Camptothecin and...
Inhibitors of human immunodeficiency virus integrase.
Fesen, M R, Kohn, K W, Leteurtre, F, Pommier, Y
In an effort to further extend the number of targets for development of antiretroviral agents, we have used an in vitro integrase assay to investigate a variety of chemicals, including topoisomerase...
Pommier, Y, Kohlhagen, G, Kohn, K W, Leteurtre, F, Wani, M C, Wall, M E
DNA topoisomerase I (top1) is a ubiquitous nuclear enzyme. It is specifically inhibited by camptothecin, a natural product derived from the bark of the tree Camptotheca acuminata. Camptothecin and...
Inhibitors of human immunodeficiency virus integrase.
Fesen, M R, Kohn, K W, Leteurtre, F, Pommier, Y
In an effort to further extend the number of targets for development of antiretroviral agents, we have used an in vitro integrase assay to investigate a variety of chemicals, including topoisomerase...