Scientific Commons: F. Liao

Vascular endothelial cadherin and role in (VE-cadherin): Cloning endothelial cell-cell adhesion (1997)

Objective: To identify proteins responsible for intercellular junction integrity in human umbilical vein endothelial cells (HUVEC), we produced a monoclonal antibody that recognized an endothelial...

A locus on chromosome 7 determines myocardial cell necrosis and calcification (dystrophic cardiac calcinosis) in mice.

Ivandic, B T, Qiao, J H, Machleder, D, Liao, F, Drake, T A, Lusis, A J

Dystrophic cardiac calcinosis, an age-related cardiomyopathy that occurs among certain inbred strains of mice, involves myocardial injury, necrosis, and calcification. Using a complete linkage map...

Tyrosine phosphorylation of phospholipase C-gamma 1 induced by cross-linking of the high-affinity or low-affinity Fc receptor for IgG in U937 cells.

Liao, F, Shin, H S, Rhee, S G

The human monocytic cell line U937 possesses two classes of the IgG Fc receptor (Fc gamma R), a high-affinity 72-kDa Fc gamma R (Fc gamma RI) and a low-affinity 40-kDa Fc gamma R (Fc gamma RII)....

Interaction of monocytes with cocultures of human aortic wall cells involves interleukins 1 and 6 with marked increases in connexin43 message.

Navab, M, Liao, F, Hough, G P, Ross, L A, Van Lenten, B J, Rajavashisth, T B, ...

Medium from cocultures of human aortic endothelial cells (HAEC) and smooth muscle cells (HASMC) taken from the same donor contained approximately two- to fourfold more macrophage colony-stimulating...

Genetic evidence for a common pathway mediating oxidative stress, inflammatory gene induction, and aortic fatty streak formation in mice.

Liao, F, Andalibi, A, Qiao, J H, Allayee, H, Fogelman, A M, Lusis, A J

In a previous survey of inbred mouse strains on an atherogenic diet, we observed that the susceptibility to aortic atherosclerotic lesion formation was associated with the accumulation of lipid...

Minimally modified low density lipoprotein is biologically active in vivo in mice.

Liao, F, Berliner, J A, Mehrabian, M, Navab, M, Demer, L L, Lusis, A J, ...

Minimally modified low density lipoprotein (MM-LDL), derived by mild iron oxidation or prolonged storage at 4 degrees C, has been shown to induce certain inflammatory responses in vascular cells in...

Genetic control of inflammatory gene induction and NF-kappa B-like transcription factor activation in response to an atherogenic diet in mice.

Liao, F, Andalibi, A, DeBeer, F C, Fogelman, A M, Lusis, A J

A high fat, high cholesterol "atherogenic" diet induced considerably greater hepatic levels of conjugated dienes and expression of several inflammatory and oxidative stress responsive genes (JE, the...