Cazzaniga, G, Alberti, F, Dell'Oro, M G, Gottardi, E, Specchia, G, ...
Mutations in exon 12 of the nucleophosmin (NPM1) gene occur in about 60% of adult AML with normal karyotype. By exploiting a specific feature of NPM1 mutants, that is insertion at residue 956 or...
Bigerna, B, Pucciarini, A, Tiacci, E, Morris, S W, ...
La Starza, R, Casas, S, Nomdedéu, J, Queipo De Llano, M P, Cimino, G, ...
We describe two cases of acute myelocytic leukemia (AML), classified as M4 and M1 in the French-American-British classification, with unbalanced translocations der(16)t(11;16)(q23;p13) and...
Bigoni, R, Bardi, A, Roberti, M G, Agostini, P, ...
To better define the incidence and significance of cryptic chromosome lesions in acute myeloid leukemia (AML), fluorescence in situ hybridization (FISH) studies were performed in interphase cells...
Göttlicher, M., Minucci, S., Zhu, P., Krämer, O.H., Schimpf, A., Giavara, S., ...
The EMBO Journal, 20(2001) S.6969-78
Göttlicher, M., Minucci, S., Zhu, P., Krämer, O.H., Schimpf, A., Giavara, S., ...
43.Frühjahrstagung der Deutschen Gesellschaft für experimentelle und klinische Pharmakologie und Toxikologie (DGPT), Mainz, 12.-14.März 2002
Göttlicher, M., Minucci, S., Zhu, P., Krämer, O.H., Schimpf, A., Giavara, S., ...
93rd Annual Meeting of the American Association for Cancer Research, San Francisco, Calif., April 6-10, 2002
Identification of genetic lesions associated with diffuse large-cell lymphoma (1994)
Dalla-Favera, R., Ye, B. H., Lo Coco, F., Gaidano, G., Lista, F., Knowles, D. M., ...
Background: The pathogenesis of several subtypes of non-Hodgkin's lymphoma (NHL) is associated with specific genetic lesions involving oncogenes and tumor-suppressor genes. These lesions inlude c-myc...
Expression pattern of the RAR alpha-PML fusion gene in acute promyelocytic leukemia.
Alcalay, M, Zangrilli, D, Fagioli, M, Pandolfi, P P, Mencarelli, A, Lo Coco, F, ...
Two chimeric genes, PML-RAR alpha and RAR alpha-PML, are formed as a consequence of the acute promyelocytic leukemia (APL)-specific reciprocal translocation of chromosomes 15 and 17 [t(15;17)]....
Alcalay, M, Zangrilli, D, Pandolfi, P P, Longo, L, Mencarelli, A, Giacomucci, A, ...
Acute promyelocytic leukemias (APLs) are characterized by a reciprocal balanced translocation that involves chromosomes 15 and 17 [t(15;17)]. We report the isolation and characterization of one of...
Expression profiles of acute lymphoblastic and myeloblastic leukemias with ALL-1 rearrangements
Rozovskaia, T., Ravid-Amir, O., Tillib, S., Getz, G., Feinstein, E., Agrawal, H., ...
The ALL-1 gene is directly involved in 5–10% of acute lymphoblastic leukemias (ALLs) and acute myeloid leukemias (AMLs) by fusion to other genes or through internal rearrangements. DNA microarrays...
Absence of HHV-8 DNA sequences in malignant mesothelioma.
Ascoli, V, Nardi, F, Carnovale Scalzo, C, Signoretti, S, Pistilli, A, Lo Coco, F
Human herpesvirus 8 (HHV-8) associated primary effusion lymphomas arise and grow in the body cavities as effusions, but it is not known whether the lining of body cavities and mesothelium derived...
Testa, U, Grignani, F, Samoggia, P, Zanetti, C, Riccioni, R, Lo Coco, F, ...
We investigated the effect of the acute promyelocytic leukemia (APL) specific PML/RARalpha fusion protein on the sensitivity to TNF-alpha-mediated apoptosis. The U937 leukemia cell line was...
Pandolfi, P P, Alcalay, M, Fagioli, M, Zangrilli, D, Mencarelli, A, Diverio, D, ...
The acute promyelocytic leukaemia (APL) 15;17 translocation generates a PML/RAR alpha chimeric gene which is transcribed as a fusion PML/RAR alpha mRNA. Molecular studies on a large series of APLs...
Expression pattern of the RAR alpha-PML fusion gene in acute promyelocytic leukemia.
Alcalay, M, Zangrilli, D, Fagioli, M, Pandolfi, P P, Mencarelli, A, Lo Coco, F, ...
Two chimeric genes, PML-RAR alpha and RAR alpha-PML, are formed as a consequence of the acute promyelocytic leukemia (APL)-specific reciprocal translocation of chromosomes 15 and 17 [t(15;17)]....
Alcalay, M, Zangrilli, D, Pandolfi, P P, Longo, L, Mencarelli, A, Giacomucci, A, ...
Acute promyelocytic leukemias (APLs) are characterized by a reciprocal balanced translocation that involves chromosomes 15 and 17 [t(15;17)]. We report the isolation and characterization of one of...
Expression profiles of acute lymphoblastic and myeloblastic leukemias with ALL-1 rearrangements
Rozovskaia, T., Ravid-Amir, O., Tillib, S., Getz, G., Feinstein, E., Agrawal, H., ...
The ALL-1 gene is directly involved in 5–10% of acute lymphoblastic leukemias (ALLs) and acute myeloid leukemias (AMLs) by fusion to other genes or through internal rearrangements. DNA microarrays...
Absence of HHV-8 DNA sequences in malignant mesothelioma.
Ascoli, V, Nardi, F, Carnovale Scalzo, C, Signoretti, S, Pistilli, A, Lo Coco, F
Human herpesvirus 8 (HHV-8) associated primary effusion lymphomas arise and grow in the body cavities as effusions, but it is not known whether the lining of body cavities and mesothelium derived...
Testa, U, Grignani, F, Samoggia, P, Zanetti, C, Riccioni, R, Lo Coco, F, ...
We investigated the effect of the acute promyelocytic leukemia (APL) specific PML/RARalpha fusion protein on the sensitivity to TNF-alpha-mediated apoptosis. The U937 leukemia cell line was...
Pandolfi, P P, Alcalay, M, Fagioli, M, Zangrilli, D, Mencarelli, A, Diverio, D, ...
The acute promyelocytic leukaemia (APL) 15;17 translocation generates a PML/RAR alpha chimeric gene which is transcribed as a fusion PML/RAR alpha mRNA. Molecular studies on a large series of APLs...