Kallioniemi, A, Kallioniemi, O P, Piper, J, Tanner, M, Stokke, T, Chen, L, ...
Comparative genomic hybridization was applied to 5 breast cancer cell lines and 33 primary tumors to discover and map regions of the genome with increased DNA-sequence copy-number. Two-thirds of...
ERBB2 amplification in breast cancer analyzed by fluorescence in situ hybridization.
Kallioniemi, O P, Kallioniemi, A, Kurisu, W, Thor, A, Chen, L C, Smith, H S, ...
We illustrate the use of fluorescence in situ hybridization (FISH) for analysis of ERBB2 oncogene copy number, the level of amplification (here defined as the ratio of ERBB2 copy number to copy...
Chen, L C, Neubauer, A, Kurisu, W, Waldman, F M, Ljung, B M, Goodson, W, ...
Loss of heterozygosity (LOH) on the short arm of chromosome 17 (17p) was found in 27 of 52 (52%) previously untreated primary breast cancers. There was a significant correlation between this 17p...
Kallioniemi, A, Kallioniemi, O P, Piper, J, Tanner, M, Stokke, T, Chen, L, ...
Comparative genomic hybridization was applied to 5 breast cancer cell lines and 33 primary tumors to discover and map regions of the genome with increased DNA-sequence copy-number. Two-thirds of...
ERBB2 amplification in breast cancer analyzed by fluorescence in situ hybridization.
Kallioniemi, O P, Kallioniemi, A, Kurisu, W, Thor, A, Chen, L C, Smith, H S, ...
We illustrate the use of fluorescence in situ hybridization (FISH) for analysis of ERBB2 oncogene copy number, the level of amplification (here defined as the ratio of ERBB2 copy number to copy...
Chen, L C, Neubauer, A, Kurisu, W, Waldman, F M, Ljung, B M, Goodson, W, ...
Loss of heterozygosity (LOH) on the short arm of chromosome 17 (17p) was found in 27 of 52 (52%) previously untreated primary breast cancers. There was a significant correlation between this 17p...
Chromosome 8p deletions are associated with invasive tumor growth in urinary bladder cancer.
Wagner, U., Bubendorf, L., Gasser, T. C., Moch, H., Görög, J. P., Richter, J., ...
Alterations of chromosome 8, including deletions of 8p, occur frequently in many tumors. In this study, fluorescence in situ hybridization was used to study the relationship between 8p deletions, 8q...
Patterns of epidermal growth factor receptor amplification in malignant gliomas.
Sauter, G., Maeda, T., Waldman, F. M., Davis, R. L., Feuerstein, B. G.
Amplification of the gene for epidermal growth factor receptor (EGFR) is a common finding in malignant gliomas. We found that 18 of 29 grade 3 and grade 4 gliomas had EGFR amplification when assayed...
c-myc copy number gains in bladder cancer detected by fluorescence in situ hybridization.
Sauter, G., Carroll, P., Moch, H., Kallioniemi, A., Kerschmann, R., Narayan, P., ...
Amplification and overexpression of c-myc have been suggested as prognostic markers in human cancer. To assess the role of c-myc gene copy number alterations in bladder cancer, 87 bladder tumors were...
Isola, J. J., Kallioniemi, O. P., Chu, L. W., Fuqua, S. A., Hilsenbeck, S. G., Osborne, C. K., ...
Breast cancer progression is determined by a complex pattern of multiple genetic aberrations the association of which with patient prognosis is unknown. In this study, we have undertaken a...
Proliferation of normal breast epithelial cells as shown by in vivo labeling with bromodeoxyuridine.
Christov, K., Chew, K. L., Ljung, B. M., Waldman, F. M., Duarte, L. A., Goodson, W. H., ...
The proliferative activity of normal acinar and ductal breast epithelial cells was studied by in vivo labeling with 5-bromodeoxyuridine (BrdUrd) in 26 cases with concurrent breast carcinoma. The...