The Impact of Uncertainties in Reaction Q-values on Nucleosynthesis in Type I X-Ray Bursts (2008)
Parikh, A., Jose, J., Iliadis, C., Moreno, F., Rauscher, T.
Nucleosynthesis in Type I X-ray bursts may involve up to several thousand nuclear processes. The majority of these processes have only been determined theoretically due to the lack of sufficient...
Cabrera, F., Murillo, J.M., Madejón, P., Domínguez, M.T., Burgos, P., Madejón, E., ...
Resumen. Tras la rotura de la balsa de residuos de la mina Los Frailes-Aznalcóllar (abril 1998), 4386 ha de suelo fueron afectadas por el vertido de unos 6 x 106 m3 de lodos y aguas ácidas, ricos...
Brey, J. Javier, Garcia-Rojo, R., Moreno, F., Ruiz-Montero, M. J.
The spontaneous symmetry breaking in a vibro-fluidized low-density granular gas in three connected compartments is investigated. When the total number of particles in the system becomes large enough,...
Hydrodynamic profiles for an impurity in a open vibrated granular gas (2006)
Brey, J. Javier, Ruiz-Montero, M. J., Moreno, F.
The hydrodynamic state of an impurity immersed in a low density granular gas is analyzed. Explicit expressions for the temperature and density fields of the impurity in terms of the hydrodynamic...
Tau Phosphorylation, Aggregation, and Cell Toxicity (2006)
I. Santa-María, M. Pérez, F. Hernández, F. Moreno
Protein aggregation takes place in many neurodegenerative disorders. However, there is a controversy about the possible toxicity of these protein aggregates. In this review, this controversy is...
Circular polarization of light scattered by asymmetrical particles (2006)
Guirado, D., Hovenier, J.W., Moreno, F.
We calculated the degree of circular polarization of light singly scattered by some types of asymmetrical particles in random orientation as a function of scattering angle, using the T-matrix method....
Energy partition and segregation for an intruder in a vibrated granular system under gravity (2005)
Brey, J. Javier, Ruiz-Montero, M. J., Moreno, F.
The difference of temperatures between an impurity and the surrounding gas in an open vibrated granular system is studied. It is shown that, in spite of the high inhomogeneity of the state, the...
Evaluación de cuatro métodos de propagación en campo de Trichanthera gigantea (2005)
El yatago (Trichantera gigantea) es una especie con amplio potencial para la producción de forrajes y la conservación de cuencas. Sin embargo, su establecimiento esta limitado por los altos costos....
Evaluación de cuatro métodos de propagación en campo de Trichanthera gigantea (2005)
Moreno, F., Guerrero, Antonio F.
El yatago (Trichantera gigantea) es una especie con amplio potencial para la producción de forrajes y la conservación de cuencas. Sin embargo, su establecimiento esta limitado por los altos costos....
Steady state representation of the homogeneous cooling state of a granular gas (2003)
Brey, J. Javier, Ruiz-Montero, M. J., Moreno, F.
The properties of a dilute granular gas in the homogeneous cooling state are mapped to those of a stationary state by means of a change in the time scale that does not involve any internal property...
Learning and Vision Mobile Robotics Group Research Report (2003)
J. Andrade, F. Moreno, R. Alquezar, J. Ar, J. Climent, A. Grau, ...
This article presents the current trends on wheeled mobile robotics being pursued at IRI-UPC-CSIC. It includes an overview of recent results produced in our group in a wide range of areas, including...
Transversal inhomogeneities in dilute vibrofluidized granular fluids (2002)
Brey, J. Javier, Ruiz-Montero, M. J., Moreno, F., Garcia-Rojo, R.
The spontaneous symmetry breaking taking place in the direction perpendicular to the energy flux in a dilute vibrofluidized granular system is investigated, using both a hydrodynamic description and...
Reprinted from Journal of the Optical Society of America B (2001)
A. Valle, F. Moreno, L. Pesquera, F. Gonzfilez, M. A. Rodriguez
INTRODUCTION The laser switch on is an example of relaxation from an unstable state. The description of this process is usually done with nonlinear Langevin-type equations in which the fluctuations...
Pelegrín Sánchez, Francisco, Moreno, F., Murillo Carpio, José Manuel
Se ha estudiado la respuesta de dos cultivos de rotación frecuente en Andalucía Occidental, trigo (Triticum aestivuni L.) y girasol (Helianthus annuus L.), al laboreo tradicional (LT) y de...
Equilibrio nutricional de un maíz ("Prisma") bajo monocultivo y diferentes dosis de abonado (2000)
Fernández, J. E., Fernández, María C., Moreno, F., Murillo Carpio, José Manuel, Cabrera Capitán, Francisco
Se ha comparado el equilibrio nutricional, y algunos parámetros de crecimiento y cosecha, de un maíz (Zea mays, L. "Prisma") en el 1º y 7º año de monocultivo, sometido a riego y dos dosis de...
Joint observations with STARE and DASI. (1999)
López-González, M. J., López-Moreno, J. J., López-Puertas, M., López-Valverde, M. A., Molina, A., Moreno, F., ...
López-González, M. J., López-Moreno, J. J., López-Puertas, M., López-Valverde, M. A., Molina, A., Moreno, F., ...
Martinez, M, Oña, Antonio, Moreno, F.
applied to control, evaluation and training in different sport situations. This system has been adapted to describes an portable and low cost automatic system the athletic start, swimming, and...
An unusual mechanism for resistance to the antibiotic coumermycin A1.
Del Castillo, I, Vizán, J L, Rodríguez-Sáinz, M C, Moreno, F
Bacterial DNA gyrases are type II topoisomerases made up of two A subunits and two B subunits. Coumarins are carbohydrate-containing antibiotics that inhibit topoisomerases II by competing with ATP...
Gall, D., Nielsen, K., Bermudez, M. R., Moreno, F., Smith, P.
A simple, rapid, inexpensive fluorescence polarization assay for the detection of antibodies to Brucella abortus in bulk tank milk samples at the farm level or at dairies with a sensitivity and...
Herrero, P, Ramírez, M, Martínez-Campa, C, Moreno, F
A well-defined set of isogenic yeast strains has been constructed whereby each strain contains a different HXK2::lacZ gene fusion integrated at the URA3 locus. These HXK2::lacZ fusions differ in the...
González-Pastor, J E, San Millán, J L, Castilla, M A, Moreno, F
The translation inhibitor microcin C7 (MccC7) is a linear heptapeptide whose N terminus has been replaced by an N-formyl group and whose C terminus has been replaced by the phosphodiester of...
Baquero, M R, Bouzon, M, Quintela, J C, Ayala, J A, Moreno, F
In the course of a study of genes located at min 44 of the Escherichia coli genome, we identified an open reading frame with the capacity to encode a 43-kDa polypeptide whose predicted amino acid...
Valero, G, Moreno, F, Graybill, J R
After 2 weeks of intravenous challenge with Mycobacterium simiae, ICR outbred mice were treated with clarithromycin, ofloxacin, or clarithromycin plus ethambutol for 4 weeks. All three therapy groups...
Genetic analysis of microcin H47 antibiotic system.
Gaggero, C, Moreno, F, Laviña, M
The microcin H47 genetic determinants span a DNA region of ca. 10 kb and represent the first description of an enterobacterial antibiotic system located in the chromosome of the producing strain....
Del Castillo, I, González-Pastor, J E, San Millán, J L, Moreno, F
In high copy number, the Escherichia coli mprA gene reduces the synthesis of peptide microcins B17 and C7 (MccB17 and MccC7) and blocks the osmoinduction of the proU operon at the transcriptional...
Del Castillo, I, Gómez, J M, Moreno, F
Microcins B17 and C7 are plasmid-determined, peptide antibiotics produced by Escherichia coli when cells enter the stationary phase of growth. Microcinogenic strains are immune to the action of the...
A hisT::Tn5 mutation affects production of microcins B17, C7, and H47 and colicin V.
Rodríguez-Sáinz, M C, Hernández-Chico, C, Moreno, F
A Tn5 insertion decreasing the production of microcin B17 was mapped to 50.2 min on the Escherichia coli chromosome map. Sequence analysis showed that the insertion disrupted hisT, the gene encoding...
Genilloud, O, Moreno, F, Kolter, R
The 3.8-kilobase segment of plasmid DNA that contains the genes required for production of the DNA replication inhibitor microcin B17 was sequenced. The sequence contains four open reading frames...
appR gene product activates transcription of microcin C7 plasmid genes.
Díaz-Guerra, L, Moreno, F, San Millán, J L
Microcin C7 (MccC7) is encoded by Escherichia coli plasmid pMccC7. However, some strains of E. coli K-12 carrying this plasmid do not produce this antibiotic. Here we show that these strains differ...
A clinical isolate of transposon Tn5 expressing streptomycin resistance in Escherichia coli.
Genilloud, O, Blázquez, J, Mazodier, P, Moreno, F
The central region of transposon Tn5 carries three antibiotic resistance markers: neo, ble, and str. The str gene codes for a phosphotransferase that inactivates streptomycin. This activity is...
Mayo, O, Hernández-Chico, C, Moreno, F
The DNA replication inhibitor peptide microcin B17 is shown to be a useful tool for preparing Escherichia coli maxicells. To illustrate its usefulness, we have identified polypeptides synthesized...
Evidence that colicin X is microcin B17.
San Millán, J L, Kolter, R, Moreno, F
The DNA replication inhibitor microcin B17 is a peptide antibiotic produced by Escherichia coli strains carrying plasmid pMccB17. Here we present evidence that antibiotic activities previously named...
Cloning and mapping of the genetic determinants for microcin C7 production and immunity.
Novoa, M A, Díaz-Guerra, L, San Millán, J L, Moreno, F
Microcin C7, a peptide antibiotic inhibitor of protein synthesis, is produced by Escherichia coli K-12 strains that carry the 43-kilobase low-copy-number plasmid pMccC7. Microcin C7 production and...
Growth phase and ompR regulation of transcription of microcin B17 genes.
Hernández-Chico, C, San Millán, J L, Kolter, R, Moreno, F
The synthesis of the peptide antibiotic microcin B17 was shown to occur as the cells entered the stationary phase of growth. This type of growth phase regulation is commonly observed in the...
Cloning and mapping of the genetic determinants for microcin B17 production and immunity.
San Millan, J L, Hernandez-Chico, C, Pereda, P, Moreno, F
Plasmid pMccB17 (70 kilobases [kb]) codes for the production of microcin B17, a peptide that inhibits DNA synthesis, and for microcin B17 immunity. A BamHI-EcoRI fragment of 5.1 kb from pMccB17 was...
Plasmid genes required for microcin B17 production.
San Millán, J L, Kolter, R, Moreno, F
The production of the antibiotic substance microcin B17 (Mcc) is determined by a 3.5-kilobase DNA fragment from plasmid pMccB17. Several Mcc- mutations on plasmid pMccB17 were obtained by both...
Gene ompR and regulation of microcin 17 and colicin e2 syntheses.
Hernández-Chico, C, Herrero, M, Rejas, M, San Millán, J L, Moreno, F
The production of microcin 17 is controlled by plasmid pRYC17. Chromosomal mutants unable to produce a normal amount of microcin were isolated in Escherichia coli. One of the mutations maps in the...
Moscat, J, Moreno, F, Herrero, C, López, C, García-Barreno, P
The existence of a bovine brain-derived endothelial cell growth factor has recently been reported, but its mode of action is unknown. We show that the endothelial cell growth factor is a potent...
Pleiotropic mutations rendering Escherichia coli K-12 resistant to bacteriophage TP1.
Wandersman, C, Moreno, F, Schwartz, M
tpo mutations, located at 74 min on the genetic map, rendered Escherichia coli K-12 resistant to TP1, a phage which can use either the OmpF protein or the LamB protein as its receptor. tpo mutants...
OmpC and LamB proteins can serve as substitute receptors for host range mutants of coliphage TuIa.
Coliphage TuIa, which uses the OmpF protein as a receptor, can adapt by mutation to using instead the OmpC or LamB protein, or both. Most of the phage mutants retained the ability to use the OmpF...
Mellado, R P, Moreno, F, Viñuela, E, Salas, M, Reilly, B E, Anderson, D L
Reference mutants of Bacillus subtilis phage phi 29 of the Madrid and Minneapolis collections were employed to construct a genetic map. Suppressor-sensitive and temperature-sensitive mutants were...
Vizán, J L, Hernández-Chico, C, Del Castillo, I, Moreno, F
Microcin B17 (MccB17) is a bactericidal peptide antibiotic which inhibits DNA replication. Two Escherichia coli MccB17 resistant mutants were isolated and the mutations were shown to map to 83 min of...
The export of the DNA replication inhibitor Microcin B17 provides immunity for the host cell.
Garrido, M C, Herrero, M, Kolter, R, Moreno, F
Microcin B17 (MccB17) is a peptide antibiotic which inhibits DNA replication in Enterobacteriaceae. Microcin-producing strains are immune to the action of the microcin. Physical and genetic studies...
A mutant of Bacillus subtilis unable to adsorb phage phi29 efficiently has been isolated. This mutant can be infected by host range mutants of the phage. Since the host range mutations map in cistron...
Microcin H47, a chromosome-encoded microcin antibiotic of Escherichia coli.
Laviña, M, Gaggero, C, Moreno, F
Microcin H47 (MccH47) is a novel microcin antibiotic produced by a natural Escherichia coli isolate. In contrast to all the other colicins and microcins examined to date, which are plasmid encoded,...
Quintana, I, Grau, M, Moreno, F, Soler, C, Ramírez, I, Soley, M
We have studied the relationship between the effect of epidermal growth factor (EGF) on glycogen metabolism and its effect on glycolysis, in rat hepatocyte suspensions. Although 10 nM glucagon or 10...
Ionophore A23187 induces a refractory state in thrombin-activated release of inositol phosphates.
Moscat, G, Moreno, F, Iglesias, S, Garcia-Barreno, P, Municio, A M
The phosphatidylinositol cycle has been proposed to be involved in the regulation of platelet functionality through the control of cytoplasmic Ca2+ levels. However, the requirements of phospholipase...
Ordiz, I, Herrero, P, Rodicio, R, Gancedo, J M, Moreno, F
IsocitrateICL1, is one of the key enzymes of the glyoxylate pathway, which operates as an anaplerotic route for replenishing the tricarboxylic acid cycle; it is required for growth of Saccharomyces...
Herrero, P, Flores, L, Moreno, F
The glucokinase gene GLK1 of the yeast Saccharomyces cerevisiae is transcriptionally regulated in response to the carbon source of the growth medium. Northern-blot analysis shows that the GLK1 gene...
Rodríguez, A, Herrero, P, Moreno, F
The key glycolytic HXK2 gene, coding for the enzyme hexokinase 2 (Hxk2p), is expressed when cells of the yeast Saccharomyces cerevisiae are grown on a fermentable medium using glucose, fructose or...
Tpk3 and Snf1 protein kinases regulate Rgt1 association with Saccharomyces cerevisiae HXK2 promoter
Palomino, A., Herrero, P., Moreno, F.
Hexokinase 2 is an essential factor for signalling repression through the Saccharomyces cerevisiae high-glucose sensing pathway. The main regulatory mechanism that controls the HXK2 gene expression...
Tau Phosphorylation, Aggregation, and Cell Toxicity
Avila, J., Santa-María, I., Pérez, M., Hernández, F., Moreno, F.
Protein aggregation takes place in many neurodegenerative disorders. However, there is a controversy about the possible toxicity of these protein aggregates. In this review, this controversy is...
Latorre, R, Gil, F, Vázquez, J M, Moreno, F, Mascarello, F, Ramirez, G
The canine flexor carpi radialis is subdivided into 2 portions. The radial portion which occupies one third of the cross-section is located caudomedially and is composed only of large type I fibres...
Skeletal muscle fibre types in the dog.
Latorre, R, Gil, F, Vázquez, J M, Moreno, F, Mascarello, F, Ramirez, G
Using a variety of histochemical methods we have investigated the mATPase reaction of skeletal muscle fibres in the dog. Types I, IIA, IIDog (peculiar to the dog) and IIC fibres were identified. The...
An unusual mechanism for resistance to the antibiotic coumermycin A1.
Del Castillo, I, Vizán, J L, Rodríguez-Sáinz, M C, Moreno, F
Bacterial DNA gyrases are type II topoisomerases made up of two A subunits and two B subunits. Coumarins are carbohydrate-containing antibiotics that inhibit topoisomerases II by competing with ATP...
Gall, D., Nielsen, K., Bermudez, M. R., Moreno, F., Smith, P.
A simple, rapid, inexpensive fluorescence polarization assay for the detection of antibodies to Brucella abortus in bulk tank milk samples at the farm level or at dairies with a sensitivity and...
Herrero, P, Ramírez, M, Martínez-Campa, C, Moreno, F
A well-defined set of isogenic yeast strains has been constructed whereby each strain contains a different HXK2::lacZ gene fusion integrated at the URA3 locus. These HXK2::lacZ fusions differ in the...
González-Pastor, J E, San Millán, J L, Castilla, M A, Moreno, F
The translation inhibitor microcin C7 (MccC7) is a linear heptapeptide whose N terminus has been replaced by an N-formyl group and whose C terminus has been replaced by the phosphodiester of...
Baquero, M R, Bouzon, M, Quintela, J C, Ayala, J A, Moreno, F
In the course of a study of genes located at min 44 of the Escherichia coli genome, we identified an open reading frame with the capacity to encode a 43-kDa polypeptide whose predicted amino acid...
Valero, G, Moreno, F, Graybill, J R
After 2 weeks of intravenous challenge with Mycobacterium simiae, ICR outbred mice were treated with clarithromycin, ofloxacin, or clarithromycin plus ethambutol for 4 weeks. All three therapy groups...
Genetic analysis of microcin H47 antibiotic system.
Gaggero, C, Moreno, F, Laviña, M
The microcin H47 genetic determinants span a DNA region of ca. 10 kb and represent the first description of an enterobacterial antibiotic system located in the chromosome of the producing strain....
Del Castillo, I, González-Pastor, J E, San Millán, J L, Moreno, F
In high copy number, the Escherichia coli mprA gene reduces the synthesis of peptide microcins B17 and C7 (MccB17 and MccC7) and blocks the osmoinduction of the proU operon at the transcriptional...
Del Castillo, I, Gómez, J M, Moreno, F
Microcins B17 and C7 are plasmid-determined, peptide antibiotics produced by Escherichia coli when cells enter the stationary phase of growth. Microcinogenic strains are immune to the action of the...
A hisT::Tn5 mutation affects production of microcins B17, C7, and H47 and colicin V.
Rodríguez-Sáinz, M C, Hernández-Chico, C, Moreno, F
A Tn5 insertion decreasing the production of microcin B17 was mapped to 50.2 min on the Escherichia coli chromosome map. Sequence analysis showed that the insertion disrupted hisT, the gene encoding...
Genilloud, O, Moreno, F, Kolter, R
The 3.8-kilobase segment of plasmid DNA that contains the genes required for production of the DNA replication inhibitor microcin B17 was sequenced. The sequence contains four open reading frames...
appR gene product activates transcription of microcin C7 plasmid genes.
Díaz-Guerra, L, Moreno, F, San Millán, J L
Microcin C7 (MccC7) is encoded by Escherichia coli plasmid pMccC7. However, some strains of E. coli K-12 carrying this plasmid do not produce this antibiotic. Here we show that these strains differ...
A clinical isolate of transposon Tn5 expressing streptomycin resistance in Escherichia coli.
Genilloud, O, Blázquez, J, Mazodier, P, Moreno, F
The central region of transposon Tn5 carries three antibiotic resistance markers: neo, ble, and str. The str gene codes for a phosphotransferase that inactivates streptomycin. This activity is...
Mayo, O, Hernández-Chico, C, Moreno, F
The DNA replication inhibitor peptide microcin B17 is shown to be a useful tool for preparing Escherichia coli maxicells. To illustrate its usefulness, we have identified polypeptides synthesized...
Evidence that colicin X is microcin B17.
San Millán, J L, Kolter, R, Moreno, F
The DNA replication inhibitor microcin B17 is a peptide antibiotic produced by Escherichia coli strains carrying plasmid pMccB17. Here we present evidence that antibiotic activities previously named...
Cloning and mapping of the genetic determinants for microcin C7 production and immunity.
Novoa, M A, Díaz-Guerra, L, San Millán, J L, Moreno, F
Microcin C7, a peptide antibiotic inhibitor of protein synthesis, is produced by Escherichia coli K-12 strains that carry the 43-kilobase low-copy-number plasmid pMccC7. Microcin C7 production and...