Intracellular σ1 receptor modulates phospholipase C and protein kinase C activities in the brainstem
Morin-Surun, M. P., Collin, T., Denavit-Saubié, M., Baulieu, E.-E., Monnet, F. P.
Most physiological effects of σ1 receptor ligands are sensitive to pertussis toxin, suggesting a coupling with cell membrane-bound G proteins. However, the cloning of the σ1 receptor has allowed...
Monnet, F P, Mahé, V, Robel, P, Baulieu, E E
N-Methyl-D-aspartate (NMDA, 200 microM) evokes the release of [3H]norepinephrine ([3H]NE) from preloaded hippocampal slices. This effect is potentiated by dehydroepiandrosterone sulfate (DHEA S),...
Intracellular σ1 receptor modulates phospholipase C and protein kinase C activities in the brainstem
Morin-Surun, M. P., Collin, T., Denavit-Saubié, M., Baulieu, E.-E., Monnet, F. P.
Most physiological effects of σ1 receptor ligands are sensitive to pertussis toxin, suggesting a coupling with cell membrane-bound G proteins. However, the cloning of the σ1 receptor has allowed...
Monnet, F P, Mahé, V, Robel, P, Baulieu, E E
N-Methyl-D-aspartate (NMDA, 200 microM) evokes the release of [3H]norepinephrine ([3H]NE) from preloaded hippocampal slices. This effect is potentiated by dehydroepiandrosterone sulfate (DHEA S),...
Monnet, F. P., Debonnel, G., Bergeron, R., Gronier, B., De Montigny, C.
1. The in vivo effects of the high affinity sigma ligands 1,3-di(2-tolyl)guanidine (DTG), (+)-N-cyclopropylmethyl-N-methyl-1,4-diphenyl-1- ethyl-but-3-en-1-ylamine hydrochloride (JO-1784),...
Monnet, F. P., De Costa, B. R., Bowen, W. D.
1. It is now widely accepted that there are two classes of sigma (sigma) binding sites, denoted sigma(1) and sigma(2), and recently sigma(3) subtype has been proposed. Selective sigma(1) and sigma(2)...