Shimizu, F., Nakamura, Y., Inano, H., Hayakawa, N., Okubo, H.
In this paper, we discussed partial discharge (PD) inception characteristics and mechanisms of magnet wires for inverter-fed motor under repetitive surge voltage application. Experimental results...
Persistent Supercurrent Atom Chip (2007)
Mukai, T., Hufnagel, C., Kasper, A., Meno, T., Tsukada, A., Semba, K., ...
Rubidium 87 atoms are trapped in an Ioffe-Pritchard potential generated with a persistent supercurrent that flows in a loop circuit patterned on a sapphire surface. The superconducting circuit is a...
Saito, A, Kazama, JJ, Iino, N, Cho, KJ, Sato, N, Yamazaki, H, ...
NORMAL AND STIMULATED RAMAN SPECTROSCOPY. (1998)
Stoicheff,Boris O., Shimizu,F., McQuillan,A. K., Clements,W., Bachmann,U.
The report is in three parts: (1) gives a detailed account of experiments on the angular dependence of stimulated Raman emission in diamond. The observed cone angles of Stokes and anti-Stokes...
THEORY OF STOKES PULSE SHAPES IN TRANSIENT STIMULATED RAMAN SCATTERING. (1998)
Carman,R. L., Shimizu,F., Wang,C. S., Bloembergen,N.
The theory of transient stimulated Raman scattering has been extended to include an arbitrary shape of the laser pump pulse. It is shown that the maximum Stokes gain depends on the total energy...
Fujii, T, Kondo, K, Shimizu, F, Sone, H, Tanaka, J, Inoue, T
An integration plasmid, pIARL28, containing the ribosomal DNA gene as a homologous recombination sequence was constructed for introduction of the alpha-acetolactate decarboxylase gene into brewer's...
Sone, H, Fujii, T, Kondo, K, Shimizu, F, Tanaka, J, Inoue, T
The nucleotide sequence of a 1.4-kilobase DNA fragment containing the alpha-acetolactate decarboxylase gene of Enterobacter aerogenes was determined. The sequence contains an entire protein-coding...
Kitamura, M, Taylor, S, Unwin, R, Burton, S, Shimizu, F, Fine, L G
To evaluate the pathophysiological function of specific molecules in the renal glomerulus, selective, sustained, and modifiable expression of such molecules will be required. Towards achieving this...
Virus-induced decrease of insulin receptors in cultured human cells.
Shimizu, F, Hooks, J J, Kahn, C R, Notkins, A L
Viral infections may produce abnormalities in carbohydrate metabolism in normal subjects and profound changes in glucose homeostasis in insulin-dependent diabetics. Using an in vitro radio-receptor...
Sagata, N, Tsuzuku-Kawamura, J, Nagayoshi-Aida, M, Shimizu, F, Imagawa, K, Ikawa, Y
Using a rabbit antiserum directed against a synthetic oligopeptide whose sequence was deduced from the nucleotide sequence of the XBL gene of bovine leukemia virus, we detected a 38-kDa protein in...
p27x-III and p21x-III, proteins encoded by the pX sequence of human T-cell leukemia virus type I.
Kiyokawa, T, Seiki, M, Iwashita, S, Imagawa, K, Shimizu, F, Yoshida, M
Human T-cell leukemia virus type I (HTLV-I) is an etiological agent of adult T-cell leukemia and has a unique sequence, pX, that contains four possible open reading frames, I-IV. p40x was previously...
Shimizu, F, Hanaumi, K, Shimizu, Y, Kumagai, K
Mouse nonimmune peripheral blood lymphocytes (PBL) plus antibody to herpes simplex virus inhibited virus dissemination in herpes simplex virus-infected 3T3 cell culture as revealed by development of...
Shimizu, F, Satoh, J, Tada, M, Kumagai, K
A rounding cell-forming--GC strain, which is a variant of a syncytial giant cell-forming herpes simplex virus (+GC Miyama strain), was highly attenuated for Swiss, BALB/c nu/nu, and nu/+ mice,...
Fujii, T, Kondo, K, Shimizu, F, Sone, H, Tanaka, J, Inoue, T
An integration plasmid, pIARL28, containing the ribosomal DNA gene as a homologous recombination sequence was constructed for introduction of the alpha-acetolactate decarboxylase gene into brewer's...
Sone, H, Fujii, T, Kondo, K, Shimizu, F, Tanaka, J, Inoue, T
The nucleotide sequence of a 1.4-kilobase DNA fragment containing the alpha-acetolactate decarboxylase gene of Enterobacter aerogenes was determined. The sequence contains an entire protein-coding...
Kitamura, M, Taylor, S, Unwin, R, Burton, S, Shimizu, F, Fine, L G
To evaluate the pathophysiological function of specific molecules in the renal glomerulus, selective, sustained, and modifiable expression of such molecules will be required. Towards achieving this...
Virus-induced decrease of insulin receptors in cultured human cells.
Shimizu, F, Hooks, J J, Kahn, C R, Notkins, A L
Viral infections may produce abnormalities in carbohydrate metabolism in normal subjects and profound changes in glucose homeostasis in insulin-dependent diabetics. Using an in vitro radio-receptor...
Sagata, N, Tsuzuku-Kawamura, J, Nagayoshi-Aida, M, Shimizu, F, Imagawa, K, Ikawa, Y
Using a rabbit antiserum directed against a synthetic oligopeptide whose sequence was deduced from the nucleotide sequence of the XBL gene of bovine leukemia virus, we detected a 38-kDa protein in...
p27x-III and p21x-III, proteins encoded by the pX sequence of human T-cell leukemia virus type I.
Kiyokawa, T, Seiki, M, Iwashita, S, Imagawa, K, Shimizu, F, Yoshida, M
Human T-cell leukemia virus type I (HTLV-I) is an etiological agent of adult T-cell leukemia and has a unique sequence, pX, that contains four possible open reading frames, I-IV. p40x was previously...
Shimizu, F, Hanaumi, K, Shimizu, Y, Kumagai, K
Mouse nonimmune peripheral blood lymphocytes (PBL) plus antibody to herpes simplex virus inhibited virus dissemination in herpes simplex virus-infected 3T3 cell culture as revealed by development of...
Shimizu, F, Satoh, J, Tada, M, Kumagai, K
A rounding cell-forming--GC strain, which is a variant of a syncytial giant cell-forming herpes simplex virus (+GC Miyama strain), was highly attenuated for Swiss, BALB/c nu/nu, and nu/+ mice,...
Monoclonal antibodies to rat renal antigens.
Shimizu, F, Orikasa, M, Sato, K, Oite, T
We have developed hybridoma cell lines which secrete monoclonal antibodies to some rat renal antigens, namely the brush border of proximal tubular epithelium and the cytoplasm of tubular cells. The...
Developmental expression of the nephritogenic antigen of monoclonal antibody 5-1-6.
Kawachi, H., Abrahamson, D. R., St John, P. L., Goldstein, D. J., Shia, M. A., Matsui, K., ...
The biogenesis of p51, the target of nephritogenic monoclonal antibody 5-1-6, was studied in the developing glomerulus by immunolocalization and metabolic labeling. The localization of p51 was...
Kagami, S., Kawakami, K., Okada, K., Kuroda, Y., Morioka, T., Shimizu, F., ...
The influences of the epitope density on cationic antigens on the fate of immune reactants and the formation of subepithelial electron dense deposits (EDD) were studied in a model of active in situ...
Modulation of mesangial cell proliferation by endothelial cells in coculture.
Saeki, T., Morioka, T., Arakawa, M., Shimizu, F., Oite, T.
The effects of direct cell contact between endothelial (ECs) and mesangial cells (MCs) on MCs proliferation were examined in a coculture system in vitro. Mitomycin C treated ECs (M-ECs) were plated...
Monocytes secrete factors regulating glycosaminoglycan synthesis in mesangial cells in vitro.
Narita, I, Morioka, T, Arakawa, M, Shimizu, F, Oite, T
The present study was conducted to determine the manner in which monocytes increase mesangial matrices, particularly glycosaminoglycans (GAGs) which interact with various other matrix components such...
Nephrotoxic serum nephritis in nude rats: the roles of host immune reactions.
Sato, T, Oite, T, Nagase, M, Shimizu, F
A description is made of renal lesions in rats induced by heterologous (rabbit) nephrotoxic serum with or without subsequent host immune reactions against it and the effects of immune reactions on...
Morioka, T, Narita, I, Shimizu, F, Oite, T
Conditioned media from human peripheral blood leucocytes treated with lipopolysaccharide (LPS) induced a marked increase in the 3H-thymidine incorporation of cultured mesangial cells at low serum...
Experimental glomerulonephritis induced by human IgG in rats.
Yamamoto, K, Oite, T, Kihara, I, Shimizu, F
Experimental immune complex glomerulonephritis was induced with human IgG (HIgG) in two strains of rats, Wistar-King-Aptekman (WKA) and spontaneously hypertensive rats (SHR). The rats were...
Nakamura, T, Matsuyama, M, Kojima, A, Ogiu, T, Kubota, A, Suzuki, Y, ...
A close relationship was assumed between the developments of nephropathy and thymoma in the previous study, in which the effect of introduction of the rat nude gene was studied in high thymoma...
Kagami, S, Miyao, M, Shimizu, F, Oite, T
The role of epitope density in cationic antigen was investigated in an active model of in situ immune complex glomerulonephritis (ICGN) using the hapten-carrier system. Trinitrophenol (TNP) was...
Hapten-specific cellular immune response producing glomerular injury.
Oite, T, Shimizu, F, Kagami, S, Morioka, T
A new model of experimental glomerulonephritis (GN) in which a cell-mediated (delayed-type) reaction predominated was established. Cationized TNP-BSA conjugates were planted in the kidney of rats by...
Monoclonal autoantibodies in Heymann nephritis.
Kimura, S, Sakurai, A, Morioka, T, Matsui, K, Nakamura, T, Yakata, M, ...
We have developed hybridoma cell lines, each of which secretes a monoclonal antibody (MoAb) to rat renal and hepatic tissue antigens, from Lewis rat with Heymann's nephritis. Three antibodies bind to...
The effect of protamine sulfate on the course of immune complex glomerulonephritis in the rat.
Oite, T, Shimizu, F, Batsford, S R, Vogt, A
In vivo studies in rats demonstrated that the binding of a highly cationic antigen (cationized human IgG, pI greater than 9.5) to glomerular polyanion could be significantly reduced by prior...
Gollner, D, Kawachi, H, Oite, T, Oka, M, Nagase, M, Shimizu, F
Susceptibility to the development of MoAb 5-1-6-induced proteinuria was investigated in four different rat strains, i.e. Brown-Norway (BN), Lewis (LEW), Sprague-Dawley (SD) and Wistar. An intravenous...
Cheng, Q L, Orikasa, M, Morioka, T, Kawachi, H, Chen, X M, Oite, T, ...
A new animal model of progressive glomerulosclerosis was developed by administering a single i.v., injection of MoAb 1-22-3 to unilaterally nephrectomized rats. Renal morphological analysis revealed...
Quantitative studies of monoclonal antibody 5-1-6-induced proteinuric state in rats.
Kawachi, H, Matsui, K, Orikasa, M, Morioka, T, Oite, T, Shimizu, F
Murine monoclonal antibody (MoAb) 5-1-6 was already reported to bind to epithelial cell foot processes and to cause proteinuria in rats. In vivo kinetics of the injected MoAb 5-1-6, relationship...
Kawachi, H, Orikasa, M, Matsui, K, Iwanaga, T, Toyabe, S, Oite, T, ...
A MoAb 1-22-3 (IgG3) was produced in mice immunized with rat glomeruli. A blotting study indicated the antigen molecule recognized by this MoAb has a molecular weight of about 25 kD, which is the...
Kawachi, H, Iwanaga, T, Toyabe, S, Oite, T, Shimizu, F
Irreversible mesangial changes with persistent proteinuria were induced in rats given two consecutive injections 2 weeks apart of a MoAb 1-22-3 to rat mesangial cell. The characteristics of the...
Sato, T, Kawachi, H, Morioka, T, Takashima, N, Saeki, T, Oite, T, ...
By immunization with rabbit immunoglobulins and the injection of a subnephritogenic dose of rabbit nephrotoxic serum (NTS), accelerated-type nephrotoxic serum nephritis (NTN) was induced in...
Takashima, N, Kawachi, H, Oite, T, Nishi, S, Arakawa, M, Shimizu, F
The effect of chlorpromazine, one of several calmodulin antagonists that inhibit cytoskeletal movement, on the local kinetics of injected proteinuria-inducing MoAb 5-1-6 was examined to test the...
Saito, K, Shimizu, F, Sato, T, Oite, T
We have investigated the effects of various extracellular matrix (ECM) components on the behaviour of human mesangial cells (HMC) in a gel culture system using a modified MTT assay method. When...
Divalency of the monoclonal antibody 5-1-6 is required for induction of proteinuria in rats.
Narisawa, M, Kawachi, H, Oite, T, Shimizu, F
A single i.v. injection of 3 mg of the F(ab')2 fragment of MoAb 5-1-6 into rats induced immediate proteinuria (128.1 +/- 80.7 mg/24 h on day 1) which lasted 1-2 days. In contrast, rats administered...
Quantitative study of mesangial injury with proteinuria induced by monoclonal antibody 1-22-3.
Kawachi, H, Oite, T, Shimizu, F
Murine MoAb 1-22-3 has already been reported to bind to the mesangial cell surface and to cause transient proteinuria and mesangial morphological changes characterized by mesangiolysis, subsequent...
Suzuki, Y, Oite, T, Shimizu, F, Yamamoto, K, Suzuki, S, Arakawa, M
IgM and IgG class rheumatoid factor (RF) containing glomerular immune complex (IC) deposits were detected in renal biopsy material from 10 out of 123 patients with various forms of glomerulonephritis...
A nephropathy induced by immunization of rats with EHS tumour.
Kazama, T, Nakamura, T, Morioka, T, Oite, T, Sato, Y, Shimizu, F
Immunization of rats with Engelbreth-Holm-Swarm tumour induced a nephropathy immunohistopathologically similar to Heymann nephritis except that IgG was deposited along the tubular basement membranes....
An active model of immune complex glomerulonephritis in the rat employing cationized antigen.
Oite, T., Shimizu, F., Kihara, I., Batsford, S. R., Vogt, A.
An active model of in situ immune complex glomerulonephritis involving a cationic antigen was established. Three weeks after immunization with human IgG, the left kidneys of Wistar rats were perfused...
MORIOKA, T, FUJIGAKI, Y, BATSFORD, S R, WOITAS, R, OITE, T, SHIMIZU, F, ...
Histone can mediate the binding of both free DNA and DNA complexed to anti-DNA antibody to the glomerular capillary wall. We tested whether preformed histone–DNA–anti-DNA immune complexes (IC)...
Thy-1 molecule associates with protein tyrosine kinase(s) in rat mesangial cells
NARISAWA-SAITO, M, YAMANASHI, Y, MORIOKA, T, OITE, T, SHIMIZU, F
Glycophosphatidylinositol (GPI)-linked Thy-1 molecules, well known cell surface markers of murine T cells, are present on the glomerular mesangial cells of the rat kidney. The administration of...