Sittler, Taylor, Zhou, Jun, Park, Joosang, Yuen, Noah K., Sarantopoulos, Stefanie, Mollick, Joseph A., ...
PURPOSE: The therapeutic importance of immune responses against single versus multiple antigens is poorly understood. There also remains insufficient understanding whether responses to one subset of...
Modeling genomic diversity and tumor dependency in malignant melanoma (2008)
Lin, William M., Baker, Alissa C., Beroukhim, Rameen, Winckler, Wendy, Feng, Whei, Marmion, Jennifer M., ...
Corrigendum: High-throughput oncogene mutation profiling in human cancer. (2007)
Thomas, Roman K, Baker, Alissa C, Debiasi, Ralph M, Winckler, Wendy, Laframboise, Thomas, Lin, William M, ...
Systematic efforts are underway to decipher the genetic changes associated with tumor initiation and progression1, 2. However, widespread clinical application of this information is hampered by an...
High-throughput oncogene mutation profiling in human cancer (2007)
Thomas, Roman K., Baker, Alissa C., Debiasi, Ralph M., Winckler, Wendy, Laframboise, Thomas, Lin, William M., ...
Soiffer, Robert, Lynch, Thomas, Mihm, Martin, Jung, Ken, Rhuda, Catherine, Schmollinger, Jan C., ...
We conducted a Phase I clinical trial investigating the biologic activity of vaccination with irradiated autologous melanoma cells engineered to secrete human granulocyte–macrophage...
ATP6S1 elicits potent humoral responses associated with immune-mediated tumor destruction
Hodi, F. Stephen, Schmollinger, Jan C., Soiffer, Robert J., Salgia, Ravi, Lynch, Thomas, Ritz, Jerome, ...
An important goal of cancer immunology is the identification of antigens associated with tumor destruction. Vaccination with irradiated tumor cells engineered to secrete granulocyte/macrophage...
Melanoma inhibitor of apoptosis protein (ML-IAP) is a target for immune-mediated tumor destruction
Schmollinger, Jan C., Vonderheide, Robert H., Hoar, Kara M., Maecker, Britta, Schultze, Joachim L., Hodi, F. Stephen, ...
The identification of antigens associated with tumor destruction is a major goal of cancer immunology. Vaccination with irradiated tumor cells engineered to secrete granulocyte–macrophage colony...
Hodi, F. Stephen, Mihm, Martin C., Soiffer, Robert J., Haluska, Frank G., Butler, Marcus, Seiden, Michael V., ...
A large number of cancer-associated gene products evoke immune recognition, but host reactions rarely impede disease progression. The weak immunogenicity of nascent tumors contributes to this failure...
Jinushi, Masahisa, Hodi, F. Stephen, Dranoff, Glenn
The activation of NKG2D on innate and adaptive cytotoxic lymphocytes contributes to immune-mediated tumor destruction. Nonetheless, tumor cell shedding of NKG2D ligands, such as MHC class I...
Soiffer, Robert, Lynch, Thomas, Mihm, Martin, Jung, Ken, Rhuda, Catherine, Schmollinger, Jan C., ...
We conducted a Phase I clinical trial investigating the biologic activity of vaccination with irradiated autologous melanoma cells engineered to secrete human granulocyte–macrophage...
ATP6S1 elicits potent humoral responses associated with immune-mediated tumor destruction
Hodi, F. Stephen, Schmollinger, Jan C., Soiffer, Robert J., Salgia, Ravi, Lynch, Thomas, Ritz, Jerome, ...
An important goal of cancer immunology is the identification of antigens associated with tumor destruction. Vaccination with irradiated tumor cells engineered to secrete granulocyte/macrophage...
Melanoma inhibitor of apoptosis protein (ML-IAP) is a target for immune-mediated tumor destruction
Schmollinger, Jan C., Vonderheide, Robert H., Hoar, Kara M., Maecker, Britta, Schultze, Joachim L., Hodi, F. Stephen, ...
The identification of antigens associated with tumor destruction is a major goal of cancer immunology. Vaccination with irradiated tumor cells engineered to secrete granulocyte–macrophage colony...
Hodi, F. Stephen, Mihm, Martin C., Soiffer, Robert J., Haluska, Frank G., Butler, Marcus, Seiden, Michael V., ...
A large number of cancer-associated gene products evoke immune recognition, but host reactions rarely impede disease progression. The weak immunogenicity of nascent tumors contributes to this failure...
Jinushi, Masahisa, Hodi, F. Stephen, Dranoff, Glenn
The activation of NKG2D on innate and adaptive cytotoxic lymphocytes contributes to immune-mediated tumor destruction. Nonetheless, tumor cell shedding of NKG2D ligands, such as MHC class I...
Hodi, F. Stephen, Butler, Marcus, Oble, Darryl A., Seiden, Michael V., Haluska, Frank G., Kruse, Andrea, ...
Cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) functions as a negative regulator of endogenous and vaccine-induced antitumor immunity. The administration of fully human anti-CTLA-4 blocking...