Fabrice Chareyre

A key role of dendritic cells in probiotic functionality. (2007)

Foligne, Benoit, Zoumpopoulou, Georgia, Dewulf, Joelle, Ben Younes, Amena, Chareyre, Fabrice, Sirard, Jean-Claude, ...

BACKGROUND: Disruption of the intestinal homeostasis and tolerance towards the resident microbiota is a major mechanism involved in the development of inflammatory bowel disease. While some bacteria...

A key role of dendritic cells in probiotic functionality. (2007)

Foligne, Benoit, Zoumpopoulou, Georgia, Dewulf, Joelle, Ben Younes, Amena, Chareyre, Fabrice, Sirard, Jean-Claude, ...

BACKGROUND: Disruption of the intestinal homeostasis and tolerance towards the resident microbiota is a major mechanism involved in the development of inflammatory bowel disease. While some bacteria...

A key role of dendritic cells in probiotic functionality. (2007)

Foligne, Benoit, Zoumpopoulou, Georgia, Dewulf, Joelle, Ben Younes, Amena, Chareyre, Fabrice, Sirard, Jean-Claude, ...

BACKGROUND: Disruption of the intestinal homeostasis and tolerance towards the resident microbiota is a major mechanism involved in the development of inflammatory bowel disease. While some bacteria...

Gene–environment interaction modulated by allelic heterogeneity in inflammatory diseases

Chamaillard, Mathias, Philpott, Dana, Girardin, Stephen E., Zouali, Habib, Lesage, Suzanne, Chareyre, Fabrice, ...

CARD15 is a major susceptibility gene for a frequent multifactorial chronic inflammatory bowel disorder, Crohn disease (CD). By using NF-κB activation assays, the cytosolic CARD15 was shown to...

Gene–environment interaction modulated by allelic heterogeneity in inflammatory diseases

Chamaillard, Mathias, Philpott, Dana, Girardin, Stephen E., Zouali, Habib, Lesage, Suzanne, Chareyre, Fabrice, ...

CARD15 is a major susceptibility gene for a frequent multifactorial chronic inflammatory bowel disorder, Crohn disease (CD). By using NF-κB activation assays, the cytosolic CARD15 was shown to...

Maternal neoangiogenesis during pregnancy partly derives from fetal endothelial progenitor cells

Nguyen Huu, Sau, Oster, Michèle, Uzan, Serge, Chareyre, Fabrice, Aractingi, Sélim, Khosrotehrani, Kiarash

Fetal progenitor cells enter the maternal circulation during pregnancy and can persist for decades. We aimed to determine the role of these cells in tissue inflammation during pregnancy. WT female...

Natural History of Meningioma Development in Mice Reveals: A Synergy of Nf2 and p16Ink4a Mutations

Kalamarides, Michel, Stemmer-Rachamimov, Anat O, Takahashi, Masaya, Han, Zhi-Yan, Chareyre, Fabrice, Niwa-Kawakita, Michiko, ...

Meningiomas account for approximately 30% of all primary central nervous system tumors and are found in half of neurofibromatosis type 2 patients often causing significant morbidity. Although most...

Nod2 Mediates Susceptibility to Yersinia pseudotuberculosis in Mice

Meinzer, Ulrich, Esmiol-Welterlin, Sophie, Barreau, Frederick, Berrebi, Dominique, Dussaillant, Monique, Bonacorsi, Stephane, ...

Nucleotide oligomerisation domain 2 (NOD2) is a component of the innate immunity known to be involved in the homeostasis of Peyer patches (PPs) in mice. However, little is known about its role during...

Tissue-specific conditional CCM2 knockout mice establish the essential role of endothelial CCM2 in angiogenesis: implications for human cerebral cavernous malformations

Boulday, Gwénola, Blécon, Anne, Petit, Nathalie, Chareyre, Fabrice, Garcia, Luis A., Niwa-Kawakita, Michiko, ...

Cerebral cavernous malformations (CCM) are vascular malformations of the brain that lead to cerebral hemorrhages. In 20% of CCM patients, this results from an autosomal dominant condition caused by...