Federico Katzen

Review TRENDS in Biotechnology Vol.23 No.3 March 2005 The past, present and future of cell-free protein synthesis (2008)

Federico Katzen, Geoffrey Chang, Wieslaw Kudlicki

Recent technical advances have revitalized cell-free expression systems to meet the increasing demands for protein synthesis. Cell-free systems offer several advantages over traditional cell-based...

DsbC activation by the N-terminal domain of DsbD

Goldstone, David, Haebel, Peter W., Katzen, Federico, Bader, Martin W., Bardwell, James C. A., Beckwith, Jon, ...

The correct formation of disulfide bonds in the periplasm of Escherichia coli involves Dsb proteins, including two related periplasmic disulfide-bond isomerases, DsbC and DsbG. DsbD is a membrane...

New Mobilizable Vectors Suitable for Gene Replacement in Gram-Negative Bacteria and Their Use in Mapping of the 3′ End of the Xanthomonas campestris pv. campestris gum Operon

Katzen, Federico, Becker, Anke, Ielmini, M. Verónica, Oddo, Cristian G., Ielpi, Luis

We describe useful vectors to select double-crossover events directly in site-directed marker exchange mutagenesis in gram-negative bacteria. These vectors contain the gusA marker gene, providing...

Xanthomonas campestris pv. campestris gum Mutants: Effects on Xanthan Biosynthesis and Plant Virulence

Katzen, Federico, Ferreiro, Diego U., Oddo, Cristian G., Ielmini, M. Verónica, Becker, Anke, Pühler, Alfred, ...

Xanthan is an industrially important exopolysaccharide produced by the phytopathogenic, gram-negative bacterium Xanthomonas campestris pv. campestris. It is composed of polymerized pentasaccharide...

Evolutionary domain fusion expanded the substrate specificity of the transmembrane electron transporter DsbD

Katzen, Federico, Deshmukh, Meenal, Daldal, Fevzi, Beckwith, Jon

Modular organization of proteins has been postulated as a widely used strategy for protein evolution. The multidomain transmembrane protein DsbD catalyzes the transfer of electrons from the cytoplasm...

The disulfide bond isomerase DsbC is activated by an immunoglobulin-fold thiol oxidoreductase: crystal structure of the DsbC–DsbDα complex

Haebel, Peter W., Goldstone, David, Katzen, Federico, Beckwith, Jon, Metcalf, Peter

The Escherichia coli disulfide bond isomerase DsbC rearranges incorrect disulfide bonds during oxidative protein folding. It is specifically activated by the periplasmic N-terminal domain (DsbDα) of...

Role and location of the unusual redox-active cysteines in the hydrophobic domain of the transmembrane electron transporter DsbD

Katzen, Federico, Beckwith, Jon

The central hydrophobic domain of the membrane protein DsbD catalyzes the transfer of electrons from the cytoplasm to the periplasm of Escherichia coli. Two cysteine residues embedded in...

DsbC activation by the N-terminal domain of DsbD

Goldstone, David, Haebel, Peter W., Katzen, Federico, Bader, Martin W., Bardwell, James C. A., Beckwith, Jon, ...

The correct formation of disulfide bonds in the periplasm of Escherichia coli involves Dsb proteins, including two related periplasmic disulfide-bond isomerases, DsbC and DsbG. DsbD is a membrane...

New Mobilizable Vectors Suitable for Gene Replacement in Gram-Negative Bacteria and Their Use in Mapping of the 3′ End of the Xanthomonas campestris pv. campestris gum Operon

Katzen, Federico, Becker, Anke, Ielmini, M. Verónica, Oddo, Cristian G., Ielpi, Luis

We describe useful vectors to select double-crossover events directly in site-directed marker exchange mutagenesis in gram-negative bacteria. These vectors contain the gusA marker gene, providing...

Xanthomonas campestris pv. campestris gum Mutants: Effects on Xanthan Biosynthesis and Plant Virulence

Katzen, Federico, Ferreiro, Diego U., Oddo, Cristian G., Ielmini, M. Verónica, Becker, Anke, Pühler, Alfred, ...

Xanthan is an industrially important exopolysaccharide produced by the phytopathogenic, gram-negative bacterium Xanthomonas campestris pv. campestris. It is composed of polymerized pentasaccharide...

Evolutionary domain fusion expanded the substrate specificity of the transmembrane electron transporter DsbD

Katzen, Federico, Deshmukh, Meenal, Daldal, Fevzi, Beckwith, Jon

Modular organization of proteins has been postulated as a widely used strategy for protein evolution. The multidomain transmembrane protein DsbD catalyzes the transfer of electrons from the cytoplasm...

The disulfide bond isomerase DsbC is activated by an immunoglobulin-fold thiol oxidoreductase: crystal structure of the DsbC–DsbDα complex

Haebel, Peter W., Goldstone, David, Katzen, Federico, Beckwith, Jon, Metcalf, Peter

The Escherichia coli disulfide bond isomerase DsbC rearranges incorrect disulfide bonds during oxidative protein folding. It is specifically activated by the periplasmic N-terminal domain (DsbDα) of...

Role and location of the unusual redox-active cysteines in the hydrophobic domain of the transmembrane electron transporter DsbD

Katzen, Federico, Beckwith, Jon

The central hydrophobic domain of the membrane protein DsbD catalyzes the transfer of electrons from the cytoplasm to the periplasm of Escherichia coli. Two cysteine residues embedded in...

Cell-free Co-expression of Functional Membrane Proteins and Apolipoprotein, Forming Soluble Nanolipoprotein Particles*S⃞

Cappuccio, Jenny A., Blanchette, Craig D., Sulchek, Todd A., Arroyo, Erin S., Kralj, Joel M., Hinz, Angela K., ...

Here we demonstrate rapid production of solubilized and functional membrane protein by simultaneous cell-free expression of an apolipoprotein and a membrane protein in the presence of lipids, leading...