Feng Chen

Rapid whole-genome mutational profiling using next-generation sequencing technologies (2008)

Smith, Douglas R., Quinlan, Aaron R., Peckham, Heather E., Makowsky, Kathryn, Tao, Wei, Woolf, Betty, ...

Forward genetic mutational studies, adaptive evolution, and phenotypic screening are powerful tools for creating new variant organisms with desirable traits. However, mutations generated in the...

Using bioinformatics techniques for gene identification in drug discovery and development (2008)

Chen, Yi-Ping Phoebe, Chen, Feng

As more and more evidence has become available, the link between gene and emergent disease has been made including cancer, heart disease and parkinsonism. Analyzing the diseases and designing drugs...

OrthoMCL-DB: querying a comprehensive multi-species collection of ortholog groups (2006)

Chen, Feng, Mackey, Aaron J., Stoeckert, Christian J., Roos, David S.

The OrthoMCL database (http://orthomcl.cbil.upenn.edu) houses ortholog group predictions for 55 species, including 16 bacterial and 4 archaeal genomes representing phylogenetically diverse lineages,...

Robust analysis of 5'-transcript ends (5'-RATE): a novel technique for transcriptome analysis and genome annotation (2006)

Gowda, Malali, Li, Haumeng, Alessi, Joe, Chen, Feng, Pratt, Richard, Wang, Guo-Liang

Complicated cloning procedures and the high cost of sequencing have inhibited the wide application of serial analysis of gene expression and massively parallel signature sequencing for genome-wide...

A gibberellin-regulated xyloglucan endotransglycosylase gene is expressed in the endosperm cap during tomato seed germination (2002)

Chen, Feng, Nonogaki, Hiroyuki, Bradford, Kent J.

Xyloglucan endotransglycosylases (XETs) modify xyloglucans, major components of primary cell walls in dicots. A cDNA encoding an XET (LeXET4) was isolated from a germinating...