Fengming Chen

Using Caenorhabditis elegans as a model organism for evaluating extracellular signal-regulated kinase docking domain inhibitors

Chen, Fengming, MacKerell, Alexander D., Luo, Yuan, Shapiro, Paul

We have recently identified several novel ATP-independent inhibitors that target the extracellular signal-regulated kinase-2 (ERK2) protein and inhibit substrate phosphorylation. To further...