Albergaria, André, Paredes, Joana, Sousa, Bárbara, Milanezi, Fernanda, Carneiro, Vítor, Bastos, Joana, ...
Abstract Introduction The expression of additional genes, other than oestrogen receptor (ER), may be important to the hormone-responsive phenotype of breast cancer. Microarray analyses have revealed...
Significance of osteopontin expression in human invasive breast tumour stroma (2009)
Rodrigues, L. R., Lopes, Nair, Sousa, Bárbara, Vieira, Daniella, Milanezi, Fernanda, Paulsson, Marie, ...
Osteopontin has been reported to stimulate cell adhesion, migration and specific signalling functions. Its overexpression has been found in melanoma, breast, lung, colorectal, stomach and ovarian...
Viana, Marta Pereira, Lopes, José M., Little, Suzie, Milanezi, Fernanda, Basto, Diana, Pardal, Fernando, ...
Background: Patients with malignant gliomas do not respond to any current therapy. Epidermal growth factor receptor (EGFR) controls several oncogenic processes, being frequently up-regulated in...
Epidermal growth factor receptor structural alterations in gastric cancer (2008)
Moutinho, Cátia, Mateus, Ana R, Milanezi, Fernanda, Carneiro, Fátima, Seruca, Raquel, Suriano, Gianpaolo
Abstract Background EGFR overexpression has been described in many human tumours including gastric cancer. In NSCLC patients somatic EGFR mutations, within the kinase domain of the protein, as well...
P-cadherin expression in breast cancer: a review (2007)
Paredes, Joana, Correia, Ana, Ribeiro, Ana, Albergaria, André, Milanezi, Fernanda, Schmitt, Fernando C
Abstract P-cadherin is frequently over-expressed in high-grade invasive breast carcinomas and has been reported to be an enhancer of migration and invasion of breast cancer cells, being correlated...
A new model of laryngitis : neuropeptide, cyclooxygenase, and cytokine profile (2007)
Rodrigues, Manuel Lima, Fernandes, Ana Valle, Lamas, Nuno Jorge, Cruz, Andrea, Baltazar, Fátima, Milanezi, Fernanda, ...
Fundação para a Ciência e Tecnologia (FCT) - POCTI/NSE/46399/2002
EGFR amplification and lack of activating mutations in metaplastic breast carcinomas (2006)
Reis Filho, Jorge S., Pinheiro, C., Lambros, M. B. K., Milanezi, Fernanda, Carvalho, S., Savage, K., ...
Metaplastic breast carcinomas are reported to harbour epidermal growth factor receptor (EGFR) overexpression in up to 80% of the cases, but EGFR gene amplification is the underlying genetic mechanism...
Metaplastic breast carcinomas are basal-like tumours (2006)
Reis Filho, Jorge S., Milanezi, Fernanda, Steele, D., Savage, K., Simpson, Pete T., Nesland, J. M., ...
Recently, an immunohistochemical panel comprising antibodies against HER2, estrogen receptor (ER), epidermal growth factor receptor (EGFR) and cytokeratin (CK) 5 ⁄ 6 was reported to identify...
Reis-Filho, Jorge S, Milanezi, Fernanda, Carvalho, Silvia, Simpson, Pete T, Steele, Dawn, Savage, Kay, ...
Abstract Introduction Metaplastic breast carcinomas constitute a heterogeneous group of neoplasms, accounting for less than 1% of all invasive mammary carcinomas. Approximately 70–80% of...
Infection with Mycobacterium ulcerans induces persistent inflammatory responses in mice (2005)
Oliveira, Martinha S., Fraga, Alexandra G., Torrado, Egídio, Castro, António G., Pereira, João P., Longatto Filho, Adhemar, ...
Buruli ulcer (BU) is a devastating, necrotizing, tropical skin disease caused by infections with Mycobacterium ulcerans. In contrast to other mycobacterioses, BU has been associated with minimal or...
Carvalho, Inês, Milanezi, Fernanda, Martins, Albino, Reis, Rui M, Schmitt, Fernando
Abstract Introduction Receptor tyrosine kinases have been extensively studied owing to their frequently abnormal activation in the development and progression of human cancers. Platelet-derived...
Carvalho, Inês, Milanezi, Fernanda, Martins, Albino, Reis, R. M., Schmitt, Fernando C.
Introduction Receptor tyrosine kinases have been extensively studied owing to their frequently abnormal activation in the development and progression of human cancers. Plateletderived growth factor...
Paredes, Joana, Albergaria, André, Oliveira, João T., Jerónimo, Carmen, Milanezi, Fernanda, Schmitt, Fernando C.
Purpose: P-cadherin overexpressionhas been reported in breast carcinomas,where itwas associated with proliferative high-grade histological tumors. This study aimed to analyze P-cadherin expression in...
Longatto Filho, Adhemar, Albergaria, André, Paredes, Joana, Moreira, M. A. R., Milanezi, Fernanda, Schmitt, Fernando C.
Objective: To study P-cadherin aberrant expression as a possible marker for cervical adenocarcinomas in cytological samples. Methods: We studied P-cadherin immunoexpression in liquid-based cervical...
Novel and classic myoepithelial/stem cell markers in metaplastic carcinomas of the breast (2003)
Reis Filho, Jorge S., Milanezi, Fernanda, Paredes, Joana, Silva, Paula, Pereira, Emílio M., Maeda, Sueli A., ...
Metaplastic carcinomas of the breast (MCBs) are unusual neoplasms characterized by an admixture of glandular epithelial components, which frequently exhibit features of squamous differentiation, and...
Reis Filho, Jorge S., Milanezi, Fernanda, Amendoeira, Isabel, Albergaria, André, Schmitt, Fernando C.
BACKGROUND. The presence of myoepithelial cells (MECs) in fine-needle aspiration biopsies (FNAB) of the breast constitute an important criterion used to diagnose benign breast lesions. However, MECs...
Naked nuclei revisited : p63 immunoexpression (2002)
Reis Filho, Jorge S., Albergaria, André, Milanezi, Fernanda, Amendoeira, Isabel, Schmitt, Fernando C.
The presence of naked nuclei (NN) in cytological preparations of fibroadenomas is a well-known finding. Regardless of their importance on the differential diagnosis of fibroadenoma and other benign...
Infection with Mycobacterium ulcerans Induces Persistent Inflammatory Responses in Mice
Oliveira, Martinha S., Fraga, Alexandra G., Torrado, Egídio, Castro, António G., Pereira, João P., Filho, Adhemar Longatto, ...
Buruli ulcer (BU) is a devastating, necrotizing, tropical skin disease caused by infections with Mycobacterium ulcerans. In contrast to other mycobacterioses, BU has been associated with minimal or...
Reis-Filho, Jorge S, Milanezi, Fernanda, Carvalho, Silvia, Simpson, Pete T, Steele, Dawn, Savage, Kay, ...
Infection with Mycobacterium ulcerans Induces Persistent Inflammatory Responses in Mice
Oliveira, Martinha S., Fraga, Alexandra G., Torrado, Egídio, Castro, António G., Pereira, João P., Filho, Adhemar Longatto, ...
Buruli ulcer (BU) is a devastating, necrotizing, tropical skin disease caused by infections with Mycobacterium ulcerans. In contrast to other mycobacterioses, BU has been associated with minimal or...
Reis-Filho, Jorge S, Milanezi, Fernanda, Carvalho, Silvia, Simpson, Pete T, Steele, Dawn, Savage, Kay, ...
P-cadherin expression in breast cancer: a review
Paredes, Joana, Correia, Ana Luísa, Ribeiro, Ana Sofia, Albergaria, André, Milanezi, Fernanda, Schmitt, Fernando C
P-cadherin is frequently over-expressed in high-grade invasive breast carcinomas and has been reported to be an enhancer of migration and invasion of breast cancer cells, being correlated with tumour...