Validation of a manual ability questionnaire in patients with systemic sclerosis (2009)
Smith, Vanessa,
Arat, Seher,
De Keyser, Filip,
Houssiau, Frédéric A,
...
OBJECTIVE: To adapt and validate a manual ability questionnaire, the ABILHAND, developed through the Rasch methodology in patients with systemic sclerosis (SSc). METHODS: The original version of the...
Clinical Observations programme in SpA: disease parameters, treatment options and practical management issues (2009)
Elewaut, Dirk,
VAN DEN BOSCH, FILIP,
Verbruggen, August,
De Keyser, Filip,
Vander Cruyssen, Bert,
Mielants, Herman
Spondyloarthritides (SpAs) are a cluster of chronic inflammatory rheumatic diseases that typically involve inflammation of axial and peripheral joint or tendon and ligament insertions, distinct...
Juvenile-onset systemic lupus erythematosus: different clinical and serological pattern than adult-onset systemic lupus erythematosus (2009)
Hoffman, IEA,
Lauwerys, BR,
De Keyser, Filip,
Huizinga, TWJ,
Isenberg, D,
Cebecauer, L,
...
Objective: To investigate differences in clinical signs and symptoms, and in antinuclear antibodies ( ANA), between patients with juvenile-onset and adult-onset systemic lupus erythematosus (SLE)....
Reversible changes in serum immunoglobulin galactosylation during the immune response and treatment of inflammatory autoimmune arthritis (2009)
Van Beneden, Katrien,
Coppieters, Ken,
Laroy, W,
De Keyser, Filip,
Hoffman, Ilse,
VAN DEN BOSCH, FILIP,
...
Objectives: Improved DNA sequencer-aided fluorophore-assisted carbohydrate electrophoresis (DSA-FACE) technology was used to monitor the changes in the galactosylation status of serum immunoglobulins...
Validation of a manual ability questionnaire in patients with systemic sclerosis (2009)
Vanthuyne, Marie,
Smith, Vanessa,
Arat, Seher,
Westhovens, Rene,
De Keyser, Filip,
Houssiau, Frederic,
...
Objective. To adapt and validate a manual ability questionnaire, the ABILHAND, developed through the Rasch methodology in patients with systemic sclerosis (SSc). Methods. The original version of the...
Melanoma inhibitory activity, a biomarker related to chondrocyte anabolism, is reversibly suppressed by proinflammatory cytokines in rheumatoid arthritis (2009)
VANDOOREN, BERNARD,
Cantaert, Tineke,
Van Lierop, MJ,
Bos, E,
De Rycke, Leen,
Veys, Eric,
...
Objective: In mice, melanoma inhibitory activity (MIA) is a chondrocyte-specific molecule with similar regulation to collagen type II. As MIA is a small secreted protein, its value as cartilage...
Systemic levels of IL-23 are strongly associated with disease activity in rheumatoid arthritis but not spondyloarthritis (2009)
Melis, Lode,
VANDOOREN, BERNARD,
Kruithof, Elli,
JACQUES, PEGGY,
DE VOS, MARTINE,
Mielants, Herman,
...
Classification models for disease: the effect of associations between markers on calculating the risk for disease by likelihood ratio products (2009)
Wittoek, Ruth,
De Keyser, Filip,
Boonen, A,
De Vlam, Kurt,
Vastesaeger, Nathan,
Mielants, Herman,
...
The risk, for disease or a bad prognosis cart be calculated by means of prediction or classification models that take into account multiple variables. Different methods exist to construct such...
Melanoma Inhibitory Activity, a biomarker related to chondrocyte anabolism, is reversibly suppressed by proinflammatory cytokines in rheumatoid arthritis (2008)
Cantaert, Tineke,
Van Lierop, Marie-José,
Bos, Ebo,
De Rycke, Leen,
Veys, Eric M,
...
OBJECTIVE: In mice, melanoma inhibitory activity (MIA) is a chondrocyte-specific molecule with a similar regulation as collagen type II. As MIA is a small secreted protein, we assessed its value as...
Reduced metallothionein expression in colonic Crohn's disease: Evidence for it new disease-modifying gene. (2008)
Laukens, Debby,
PEELERS, H,
Waeytens, Anouk,
Bogaert, Sara,
Vander Cruyssen, Bert,
Elewaut, Dirk,
...
Local and systemic levels of IL-23 are strongly associated with disease activity in rheumatoid arthritis but not spondyloarthritis (2008)
VANDOOREN, BERNARD,
Melis, Lode,
Kruithof, Elli,
Jacques, Peggy,
De Vos, Martine,
Mielants, Herman,
...
Synovial detection and autoantibody reactivity of processed citrullinated isoforms of vimentin in inflammatory arthritides (2008)
Tilleman, Kelly,
VAN STEENDAM, K,
Cantaert, Tineke,
De Keyser, Filip,
Elewaut, Dirk,
Deforce, Dieter
Do all anti-citrullinated protein/peptide antibody tests measure the same? Evaluation of discrepancy between anti-citrullinated protein/peptide antibody tests in patients with and without rheumatoid arthritis (2008)
Vander Cruyssen, Bert,
NOGUEIRA, L,
Van Praet, Jens,
Deforce, Dieter,
Elewaut, Dirk,
SERRE, G,
...
Validation of a new screening strategy for anti-ENA antibodies (2008)
Van Praet, Jens,
Vander Cruyssen, Bert,
BONROY, C,
Smith, Vanessa,
DELANGHE, J,
De Keyser, Filip
Spontaneous amelioration in early RA: Role of antibody profiles in predicting decrease of disease activity (2008)
Vander Cruyssen, Bert,
MILTENBURG, AMM,
VAN DEN BOSCH, FILIP,
HOUBIERS, J,
Wittoek, Ruth,
BOOTS, AMH,
...
Prediction models for disease: The effect of associations between markers on calculating the risk for disease by likelihood ratio products in SpA (2008)
Vander Cruyssen, Bert,
Wittoek, Ruth,
BOONEN, A,
De Vlam, Kurt,
VASTESAEGER, N,
NOEL, W,
...
Tapering infliximab dosages after temporary dose increase does not affect treatment survival in an established RA population (2008)
Vander Cruyssen, Bert,
WESTHOVENS, R,
DUREZ, P,
VAN DEN BOSCH, FILIP,
Mielants, Herman,
DE CLERCK, L,
...
Over-representation of construction-related occupations in male patients with systemic sclerosis (2008)
Smith, Vanessa,
Vanthuyne, M.,
Vander Cruyssen, Bert,
Van Praet, Jens,
Vermeiren, F.,
Smets, H.,
...
Aims: Based on preliminary observations, we tested the hypothesis that construction-related occupations are associated with systemic sclerosis (SSc). Methods: The professional occupation of 91...
CARD15 variants determine a disturbed early response of monocytes to adherent-invasive Escherichia coli strain LF82 in Crohn's disease (2007)
Peeters, Harald,
Bogaert, Sara,
Laukens, Debby,
Rottiers, Pieter,
De Keyser, Filip,
DARFEUILLE-MICHAUD, A,
...
In pursuit of B-cell synovial autoantigens in rheumatoid arthritis: Confirmation of citrullinated fibrinogen, detection of vimentin, and introducing carbonic anhydrase as a possible new synovial autoantigen (2007)
Tilleman, Kelly,
Union, Ann,
CANTAERT, T,
DE KEYSER, S,
DANIELS, A,
Elewaut, Dirk,
...
Decrease of disease activity under ineffective therapy in DMARD-naive patients with early rheumatoid arthritis: Role of antibody profiles and carriage of the HLA shared epitope in predicting decrease of disease activity (2007)
VANDER CRUYSSEN, BERT,
MILTENBURG, AMM,
Van Den Bosch, Filip,
HOUBIERS, JGA,
Wittoek, Ruth,
BOOTS, AMH,
...
Endogenous HLA-DR-restricted presentation of the cartilage antigens human cartilage gp-39 and melanoma inhibitory activity in the inflamed rheumatoid joint (2007)
VAN LIEROP, MJC,
DEN HOED, L,
HOUBIERS, J,
VENCOVSKY, J,
RUZICKOVA, S,
KRYSTUFKOVA, O,
...
Effects of intra-articular corticosteroids and anti-TNF therapy on neutrophil activation in rheumatoid arthritis (2007)
WITTKOWSKI, H,
FOELL, D,
AF KLINT, E,
DE RYCKE, LEEN,
De Keyser, Filip,
FROSCH, M,
...
Non-pathogenic antinuclear antibodies contribute to the clearance of apoptotic antigens released during TNF alpha blockade in spondyloarthritis (SpA) (2007)
Cantaert, Tineke,
DE RYCKE, LEEN,
Vandooren, Bernard,
WIJBRANDTS, C,
Kruithof, Elli,
De Keyser, Filip,
...
Anti-TNFalpha induced apoptosis contributes to the induction of autoantibodies but not the decrease of synovial inflammation in spondyloarthropathy (SpA) (2007)
DE RYCKE, LEEN,
Cantaert, Tineke,
Vandooren, Bernard,
Kruithof, Elli,
WIJBRANDTS, CA,
De Keyser, Filip,
...
A prospective randomised multicentre study comparing continuous and intermittent treatment with celecoxib in patients with osteoarthritis of the knee or hip (2007)
LUYTEN, FP,
GEUSENS, P,
MALAISE, M,
DE CLERCK, L,
WESTHOVENS, R,
RAEMAN, F,
...
Prediction models for rheumatoid arthritis during diagnostic investigation: evaluation of combinations of rheumatoid factor, anti-citrullinated protein/peptide antibodies and the human leucocyte antigen-shared epitope (2007)
VANDER CRUYSSEN, BERT,
Hoffman, Ilse,
Peene, Isabelle,
Union, Ann,
Mielants, Herman,
MEHEUS, L,
...
Polymorphisms in the ficolin 1 gene (FCN1) are associated with susceptibility to the development of rheumatoid arthritis (2007)
VANDER CRUYSSEN, BERT,
NUYTINCK, L,
Boullart, Luc,
Elewaut, Dirk,
Waegeman, Willem,
VAN THIELEN, M,
...
CARD15 variants determine an early disturbed response of monocytes to Adherent-invasive Escherichia coli strain LF82 in Crohn’s Disease (2007)
PEETERS, HARALD,
Bogaert, Sara,
Laukens, Debby,
Rottiers, Pieter,
De Keyser, Filip,
Darfeuille-Michaud, A,
...
Caspase activation and recruitment domain 15 (CARD15) and Toll-like receptor 4 (TLR4) are respectively intracellular and membrane-bound receptors for bacterial cell wall components [respectively...
Response to the commentary 'Pooled indices to measure rheumatoid arthritis activity: a good reflection of the physician's mind' (2006)
Vander Cruyssen, Bert,
Durez, Patrick,
Westhovens, Rene,
Vastesaeger, Nathan,
Geldhof, Anja,
De Keyser, Filip
No abstract available.
Prediction of dose escalation for rheumatoid arthritis patients under infliximab treatment (2006)
Cruyssen, Bert Vander,
Meeus, Jeroen,
Wyns, Bart,
Durez, Patrick,
...
Rheumatoid arthritis (RA) is a chronic inflammatory joint disease that leads to irreversible joint destruction. To prevent this, new biological therapies, such as infliximab, have been successfully...
Diagnostic value of anti-human citrullinated fibrinogen ELISA and comparison with four other anti-citrullinated protein assays (2006)
Vander Cruyssen, Bert,
Cantaert, Tineke,
Nogueira, Leonor,
Clavel, Cyril,
De Rycke, Leen,
Dendoven, Amélie,
...
Abstract We studied the diagnostic performance of the anti-human citrullinated fibrinogen antibody (AhFibA) ELISA for rheumatoid arthritis (RA) in a consecutive cohort (population 1) and evaluated...
Four-year follow-up of infliximab therapy in rheumatoid arthritis patients with long-standing refractory disease: attrition and long-term evolution of disease activity (2006)
Cruyssen, Bert,
Van Looy, Stijn,
Wyns, Bart,
Westhovens, Rene,
Durez, Patrick,
Van Den Bosch, Filip,
...
Abstract Although there is strong evidence supporting the short-term efficacy and safety of anti-tumour necrosis factor-α agents, few studies have examined the long-term effects. We evaluated 511...
Comparison of the anti-human citrullinated fibrinogen antibodies assayed by ELISA with 2 other ACPA assays: Diagnostic value and agreement between assays (2006)
Vander Cruyssen, Bert,
NOGUEIRA, L,
Cantaert, Tineke,
CAVEL, C,
DE RYCKE, LEEN,
SEBAG, M,
...
Anti-TNFalpha induced apoptosis contributes to the induction of autoantibodies but not the decrease of synovial inflammation in spondyloarthropathy (2006)
Cantaert, Tineke,
DE RYCKE, LEEN,
Vandooren, Bernard,
KRUITHOF, ELLI,
WIJBRANDTS, C,
De Keyser, Filip,
...
Anti-TNF alpha induced apoptosis contributes to the induction of Autoantibodies but not the decrease of synovial inflammation in spondyloarthropathy (SPA) (2006)
Cantaert, Tineke,
DE RYCKE, LEEN,
Vandooren, Bernard,
KRUITHOF, ELLI,
De Keyser, Filip,
Veys, Eric,
...
Growth promoting effect of human cartilage glycoprotein-39 (HC gp-39) on synovial fibroblasts (2006)
Vandooren, Bernard,
VERHEIJDEN, G,
Cantaert, Tineke,
BOS, E,
Veys, Eric,
De Keyser, Filip,
...
Identification of synovial biomarkers of response to treatment in spondyloarthropathy (2006)
Vandooren, Bernard,
KRUITHOF, ELLI,
DE RYCKE, LEEN,
De Keyser, Filip,
FITZGERALD, O,
MCINNES, L,
...
Synovial inflammation does not change in the absence of effective treatment: implications for the use of synovial histopathology as biomarker in early phase clinical trials in rheumatoid arthritis (2006)
Baeten, Dominique,
HOUBIERS, J,
KRUITHOF, ELLI,
Vandooren, Bernard,
Van Den Bosch, Filip,
BOOTS, AM,
...
Identification of synovial biomarkers of response to experimental treatment in early-phase clinical trials in spondylarthritis (2006)
KRUITHOF, ELLI,
DE RYCKE, LEEN,
Vandooren, Bernard,
De Keyser, Filip,
FITZGERALD, O,
MCINNES, I,
...
Leflunomide and methotrexate combination therapy in daily clinical practice (2006)
DENDOOVEN, A,
DE RYCKE, LEEN,
VERHELST, X,
Mielants, Herman,
Veys, Eric,
De Keyser, Filip
Effect of age on prevalence of anticitrullinated protein/peptide antibodies in polyarticular juvenile idiopathic arthritis (2006)
DEWINT, PIETER,
Hoffman, Ilse,
ROGGE, S,
JOOS, R,
Union, Ann,
DEHOORNE, J,
...
Accuracy of anti-ribosomal P protein antibody testing for the diagnosis of neuropsychiatric systemic lupus erythematosus - An international meta-analysis (2006)
KARASSA, FB,
AFELTRA, A,
AMBROZIC, A,
CHANG, DM,
De Keyser, Filip,
DORIA, A,
...
Mannose-binding lectin (MBL2) polymorphisms in rheumatoid arthritis (RA) are not associated with susceptibility or radiological progression rate (2006)
DE RYCKE, LEEN,
Peene, Isabelle,
KRUITHOF, ELLI,
NUYTINCK, L,
Veys, Eric,
...
Four year follow-up of infliximab in rheumatoid arthritis patients refractory to multiple dmard treatment: Long-term clinical effect and prediction of attrition (2006)
Vander Cruyssen, Bert,
WESTHOVENS, R,
DUREZ, P,
Van Den Bosch, Filip,
Mielants, Herman,
DE CLERCK, L,
...
Alternative method to identify susceptibility genes for Crohn's disease through transcriptome analysis (2006)
LAUKERS, D,
PECTERS, H,
De Keyser, Filip,
Veys, Eric,
Cuvelier, Claude,
Elewaut, Dirk,
...
Altered gut transcriptome in spondyloarthropathy (2006)
Laukens, Debby,
Peeters, Harald,
Vander Cruyssen, Bert,
Boonefaes, Tom,
Elewaut, Dirk,
De Keyser, Filip,
...
Diagnostic value of anti-human citrullinated fibrinogen ELISA and comparison with four other anti-citrullinated protein assays (2006)
Vander Cruyssen, Bert,
Cantaert, Tineke,
NOGUEIRA, L,
CLAVEL, C,
DE RYCKE, LEEN,
DENDOVEN, A,
...
Four-year follow-up of infliximab therapy in rheumatoid arthritis patients with long-standing refractory disease: attrition and long-term evolution of disease activity (2006)
Vander Cruyssen, Bert,
Van Looy, Stijn,
Wyns, Bart,
WESTHOVENS, R,
DUREZ, P,
Van Den Bosch, Filip,
...
Prediction of dose escalation for rheumatoid arthritis patients under infliximab treatment (2006)
Van Looy, Stijn,
Vander Cruyssen, Bert,
Meeus, Jeroen,
Wyns, Bart,
WESTHOVENS, R,
DUREZ, P,
...
The diagnostic value of the anti-human citrullinated fibrinogen antibodies by elisa compared to anti-CCP2 antibodies, and their agreement with ACPA detected by 3 other substrates (2006)
Vander Cruyssen, Bert,
Nogueira, L,
Cantaert, T,
Cavel, C,
De Rycke, Lies,
Sebag, M,
...
DAS28 best reflects the physician's clinical judgment of response to infliximab therapy in rheumatoid arthritis patients: validation of the DAS28 score in patients under infliximab treatment (2005)
Vander Cruyssen, Bert,
Van Looy, Stijn,
Wyns, Bart,
Westhovens, Rene,
Durez, Patrick,
Van Den Bosch, Filip,
...
Abstract This study is based on an expanded access program in which 511 patients suffering from active refractory rheumatoid arthritis (RA) were treated with intravenous infusions of infliximab (3...
Synovial histopathology of psoriatic arthritis, both oligo- and polyarticular, resembles spondyloarthropathy more than it does rheumatoid arthritis (2005)
Kruithof, Elli,
Baeten, Dominique,
De Rycke, Leen,
Vandooren, Bernard,
Foell, Dirk,
Roth, Johannes,
...
Abstract At present only few biological data are available to indicate whether psoriatic arthritis (PsA) is part of the spondyloarthropathy (SpA) concept, whether it is a separate disease entity or a...
Infiltration of the synovial membrane with macrophage subsets and polymorphonuclear cells reflects global disease activity in spondyloarthropathy (2005)
Baeten, Dominique,
Kruithof, Elli,
De Rycke, Leen,
Boots, Anemieke M,
Mielants, Herman,
Veys, Eric M,
...
Abstract Considering the relation between synovial inflammation and global disease activity in rheumatoid arthritis (RA) and the distinct but heterogeneous histology of spondyloarthropathy (SpA)...
Comparison of Machine Learning models for prediction of dose increase in patients with rheumatoid arthritis (2005)
Van Looy, Stijn,
Meeus, Jeroen,
Wyns, Bart,
Vander Cruyssen, Bert,
Boullart, Luc,
De Keyser, Filip
Comparing statistics with machine learning models to predict dose increase of Infliximab for rheumatoid arthritis patients (2005)
Van Looy, Stijn,
Vander Cruyssen, Bert,
Wyns, Bart,
Meeus, Jeroen,
De Keyser, Filip,
Boullart, Luc
Feature selection in the prediction of Infliximab dose increase (2005)
Van Looy, Stijn,
Meeus, Jeroen,
Wyns, Bart,
Vander Cruyssen, Bert,
De Keyser, Filip,
Boullart, Luc
The effect of TNFalpha blockade on the antinuclear antibody profile in patients with chronic arthritis: biological and clinical implications (2005)
De Rycke, Leen,
Baeten, Dominique,
Kruithof, Elli,
Van Den Bosch, Filip,
Veys, Eric,
De Keyser, Filip
Relative increase in lung volume in fetuses with congenital diaphragmatic hernia treated by fetoscopic endoluminal tracheal occlusion (FETO) (2005)
CANNIE, M,
JANI, J,
VAN SCHOUBROECK, D,
De Keyser, Filip,
MARCHAL, G,
GALLOT, D,
...
S100A12-expression is upregulated by TNF and may serve as a marker for the success of anti-TNF therapy (2005)
WITTKOWSKI, H,
ULFGREN, AK,
De Rycke, Leen,
De Keyser, Filip,
KLARESKOG, L,
ROTH, J,
...
Mannose-binding lectin (Mbl2) polymorphisms in rheumatoid arthritis are not associated with susceptibility, radiological progression rate, or serological markers (2005)
De Rycke, Leen,
Peene, Isabelle,
Kruithof, Elli,
Hoffman, Ilse,
Vander Cruyssen, Bert,
JURAS, J,
...
Growth promoting effect of human cartilage glycoprotein-39 (HC gp-39)on synovial fibroblasts (2005)
Vandooren, Bernard,
VERHEIJDEN, G,
BOS, E,
Veys, Eric,
De Keyser, Filip,
BOOTS, AM,
...
Local production of the cartilage protein melanoma inhibitory activity (MIA) in the inflamed joint: Disease specificity, regulation by IL-1, and association with radiological joint damage (2005)
Vandooren, Bernard,
VAN LIEROP, MJC,
Veys, Eric,
BOOTS, AM,
BOS, E,
De Keyser, Filip,
...
Identification of synovial biomarkers of response to treatment in spondyloarthropathy (2005)
Kruithof, Elli,
De Rycke, Leen,
De Keyser, Filip,
FITZGERALD, O,
MCINNES, I,
TAK, PP,
...
Involvement of neurotrophins and their receptors in spondyloarthritis synovitis: relation to inflammation and response to treatment (2005)
RIHL, M,
Kruithof, Elli,
BARTHEL, C,
De Keyser, Filip,
Veys, Eric,
ZEIDLER, H,
...
Anti-citrullinated protein/peptide antibodies (ACPA) in rheumatoid arthritis: Specificity and relation with rheumatoid factor (2005)
Vander Cruyssen, Bert,
Peene, Isabelle,
Cantaert, Tineke,
Hoffman, Ilse,
De Rycke, Leen,
Veys, Eric,
...
Functional haplotypes of PADI4: relevance for rheumatoid arthritis specific synovial intracellular citrullinated proteins and anticitrullinated protein antibodies (2005)
Cantaert, Tineke,
COUCKE, P,
De Rycke, Leen,
Veys, Eric,
De Keyser, Filip,
Baeten, Dominique
Mannose-binding lectin polymorphisms in rheumatoid arthritis and the associations with radiological progression rate and serological markers (2005)
De Rycke, Leen,
Peene, Isabelle,
Kruithof, Elli,
NUYTINCK, L,
Veys, Eric,
...
IgM anti-dsDNA autoantibodies are the main antinuclear reactivity induced by infliximab but not etanercept treatment in vivo: Biological and clinical implications (2005)
De Rycke, Leen,
Baeten, Dominique,
Kruithof, Elli,
Van Den Bosch, Filip,
Veys, Eric,
De Keyser, Filip
Human cartilage glycoprotein-39 (HC gp-39) as growth factor for synovial fibroblasts (2005)
Vandooren, Bernard,
VERHEIJDEN, G,
BOS, E,
Veys, Eric,
De Keyser, Filip,
BOOTS, A,
...
The cartilage protein Melanoma Inhibitory Activity (MIA) is produced locally in the arthritic joint but does not correlate with radiological joint damage (2005)
Vandooren, Bernard,
VAN LIEROP, M,
ROVERS, E,
BRUISTEN, M,
Veys, Eric,
BOOTS, A,
...
Functional haplotypes of PAD14: Relevance for rheumatoid arthritis-specific synovial intracellular citruillinated proteins and anti-citrullinated protein antibodies (2005)
Cantaert, Tineke,
COUCKE, R,
De Rycke, Leen,
Veys, Eric,
De Keyser, Filip,
Baeten, Dominique
Synovial intracellular citrullinated proteins colocalizing with peptidyl arginine deiminase are pathophysiologically relevant antigenic determinants of rheumatoid arthritis-specific humoral autoimmunity (2005)
De Rycke, Leen,
NICHOLAS, AR,
Cantaert, Tineke,
Kruithof, Elli,
ECHOLS, JD,
VANDEKERCKHOVE, B,
...
Das28 correlates best with the physician's clinical judgment of response to infliximab therapy in rheumatoid arthritis patients (2005)
Vander Cruyssen, Bert,
Van Looy, Stijn,
WESTHOVENS, R,
DUREZ, P,
Van Den Bosch, Filip,
VEYS, EM,
...
Impact of natural changes in disease activity on synovial histopathology in rheumatoid arthritis (2005)
Baeten, Dominique,
HOUBIERS, J,
Kruithof, Elli,
Vandooren, Bernard,
Van Den Bosch, Filip,
BOOTS, A,
...
Tumor necrosis factor a blockade treatment down-modulates the increased systemic and local expression of toll-like receptor 2 and toll-like receptor 4 in spondylarthropathy (2005)
De Rycke, Leen,
Vandooren, Bernard,
Kruithof, Elli,
De Keyser, Filip,
Veys, Eric,
Baeten, Dominique
Infliximab, but not etanercept, induces IgM anti-double-stranded DNA autoantibodies as main antinuclear reactivity - Biologic and clinical implications in autoimmune arthritis (2005)
De Rycke, Leen,
Baeten, Dominique,
Kruithof, Elli,
Van Den Bosch, Filip,
Veys, Eric,
De Keyser, Filip
Synovial intracellular citrullinated proteins colocalizing with peptidyl arginine deiminase are pathophysiologically relevant antigenic determinants of rheumatoid arthritis-specific humoral autoimmunity (2005)
De Rycke, Leen,
NICHOLAS, AP,
Cantaert, Tineke,
Kruithof, Elli,
ECHOLS, JD,
VANDEKERCKHOVE, B,
...
Increased systemic and local expression of toll-like receptor 2 and 4 in spondyloarthropathy is downmodulated by tumour necrosis factor alpha blockade (2005)
De Rycke, Leen,
Vandooren, Bernard,
Kruithof, Elli,
De Keyser, Filip,
Veys, Eric,
Baeten, Dominique
Mannose-binding lectin polymorphisms in rheumatoid arthritis and the associations with radiological progression rate and serological markers (2005)
De Rycke, Leen,
Peene, Isabelle,
Kruithof, Elli,
NUYTINCK, L,
Veys, Eric,
...
Fibrin deimination in synovial tissue is not specific for rheumatoid arthritis but commonly occurs during synovitides (2005)
CHAPUY-REGAUD, S,
SEBBAG, M,
Baeten, Dominique,
CLAVEL, C,
FOULQUIER, C,
De Keyser, Filip,
...
Differential expression and response to anti-TNF alpha treatment of infiltrating versus resident tissue macrophage subsets in autoimmune arthritis (2005)
De Rycke, Leen,
Baeten, Dominique,
FOELL, D,
Kruithof, Elli,
Veys, Eric,
ROTH, J,
...
Rheumatoid factor, but not anti-cyclic citrullinated peptide antibodies, is modulated by infliximab treatment in rheumatoid arthritis (2005)
De Rycke, Leen,
Verhelst, Xavier,
Kruithof, Elli,
Van Den Bosch, Filip,
Hoffman, Ilse,
Veys, Eric,
...
Presence of rheumatoid factor and antibodies to citrullinated peptides in systemic lupus erythematosus (2005)
Hoffman, Ilse,
Peene, Isabelle,
CEBECAUER, L,
ISENBERG, D,
HUIZINGA, TWJ,
Union, Ann,
...
Diagnostic performance and predictive value of rheumatoid factor, anti-citrullinated peptide antibodies, and the HLA shared epitope for diagnosis of rheumatoid arthritis (2005)
Hoffman, Ilse,
Peene, Isabelle,
POTTEL, H,
Union, Ann,
HULSTAERT, F,
MEHEUS, L,
...
Infiltration of the synovial membrane with macrophage subsets and polymorphonuclear cells reflects global disease activity in spondyloarthropathy (2005)
Baeten, Dominique,
Kruithof, Elli,
De Rycke, Leen,
BOOTS, AM,
Mielants, Herman,
Veys, Eric,
...
Histological evidence that infliximab treatment leads to downregulation of inflammation and tissue remodelling of the synovial membrane in spondyloarthropathy (2005)
Kruithof, Elli,
Baeten, Dominique,
Van Den Bosch, Filip,
Mielants, Herman,
Veys, Eric,
De Keyser, Filip
Chronically inflamed synovium from spondyloarthropathy and rheumatoid arthritis investigated by protein expression profiling followed by tandem mass spectrometry (2005)
Tilleman, Kelly,
Van Beneden, Katrien,
Dhondt, Aline,
Hoffman, Ilse,
De Keyser, Filip,
Veys, Eric,
...
Short and long term synovial immunumodulation by etanercept in spondyloarthropathy (2005)
Kruithof, Elli,
De Rycke, Leen,
Van Den Bosch, Filip,
Mielants, Herman,
Veys, Eric,
De Keyser, Filip,
...
5-year safety and efficacy follow-up in 107 spondyloarthropathy patients with continued long-term infliximab treatment (2005)
Van Den Bosch, Filip,
DEVINCK, MIEKE,
Kruithof, Elli,
VERBRUGGEN, G,
De Keyser, Filip,
Mielants, Herman,
...
Synovial histopathology of psoriatic arthritis, both oligo- and polyarticular, resembles spondyloarthropathy more than it does rheumatoid arthritis (2005)
Kruithof, Elli,
Baeten, Dominique,
De Rycke, Leen,
Vandooren, Bernard,
FOELL, D,
ROTH, J,
...
Anti-citrullinated peptide antibodies may occur in patients with psoriatic arthritis (2005)
Vander Cruyssen, Bert,
Hoffman, Ilse,
Zmierczak, Hans-Georg,
Van Den Berghe, Marthe,
Kruithof, Elli,
De Rycke, Leen,
...
DAS28 best reflects the physician's clinical judgment of response to infliximab therapy in rheumatoid arthritis patients: validation of the DAS28 score in patients under infliximab treatment (2005)
Vander Cruyssen, Bert,
Van Looy, Stijn,
Wyns, Bart,
WESTHOVENS, R,
DUREZ, P,
MALAISE, M,
...
Juvenile chronic arthritis displays synovial features distinct from both spondyloarthropathy and rheumatoid arthritis (2005)
Kruithof, Elli,
De Rycke, Leen,
Vandooren, Bernard,
JOOS, R,
Elewaut, Dirk,
...
Effective immunomodulation of peripheral joint pathology in spondyloarthropathy by etanercept (2005)
Kruithof, Elli,
De Rycke, Leen,
ROTH, J,
Mielants, Herman,
Van Den Bosch, Filip,
De Keyser, Filip,
...
DAS28 is a robust measure of the physician's clinical judgment of response infliximab therapy (2005)
Vander Cruyssen, Bert,
Van Looy, Stijn,
Wyns, Bart,
WESTHOVENS, R,
DUREZ, P,
...
Differential expression of hypoxia activated proteins in synovial tissue of inflammatory arthritides (2005)
TILLEMAN, K,
DHONDT, A,
Dewint, Pieter,
De Keyser, Filip,
Elewaut, Dirk,
Deforce, Dieter
Preliminary evidence for a retardation of structural damage in patients with ankylosing spondylitis continuously treated with infliximab for 4 years (2005)
Van Den Bosch, Filip,
DEVINCK, MIEKE,
Kruithof, Elli,
Hoffman, Ilse,
VERBRUGGEN, G,
De Keyser, Filip,
...
Mannose-binding lectin (MBL2) polymorphisms in rheumatoid arthritis (RA) are not associated with susceptibility or radiological progression rate (2005)
De Rycke, Leen,
Peene, Isabelle,
Kruithof, Elli,
NUYTINCK, L,
Veys, Eric,
...
Immunomodulatory effects of etanercept on peripheral joint synovitis in the spondylarthropathies (2005)
Kruithof, Elli,
De Rycke, Leen,
ROTH, J,
Mielants, Herman,
Van Den Bosch, Filip,
De Keyser, Filip,
...
Differential expression of hypoxia activated proteins in synovial tissue of inflammatory arthritides (2005)
Tilleman, Kelly,
Dhondt, Aline,
DEWINT, PIETER,
De Keyser, Filip,
Elewaut, Dirk,
Deforce, Dieter
Colon mucosa of patients both with spondyloarthritis and Crohn's disease is enriched with macrophages expressing the scavenger receptor CD163 (2005)
Demetter, Pieter,
De Vos, Martine,
Van Huysse, Jacques,
Baeten, Dominique,
Ferdinande, Liesbeth,
Peeters, Harald,
...
CARD15 polymorphisms are associated with anti-Saccharomyces cerevisiae antibodies in caucasian Crohn's disease patients (2005)
Vander Cruyssen, Bert,
Peeters, Harald,
Hoffman, Ilse,
Laukens, Debby,
Coucke, Paul,
MARICHAL, DENIS,
...
CARD15 gene polymorphisms in patients with spondyloarthropathies identify a specific phenotype previously related to Crohn's disease (2005)
LAUKENS, DEBBY,
Peeters, Harald,
MARICHAL, DENIS,
Vander Cruyssen, Bert,
Mielants, Herman,
Elewaut, Dirk,
...
Case number 34: Relapse of polyarteritis nodosa presenting as isolated and localised lower limb periostitis (2005)
CARRON, P,
Hoffman, Ilse,
De Rycke, Leen,
Peene, Isabelle,
Veys, Eric,
De Keyser, Filip,
...
Comparing statistics with machine learning models to predict dose increase of infliximab for rheumatoid arthritis patients (2005)
VAN LOOY, S,
VANDER CRUYSSEN, B,
Wyns, Bart,
Meeus, Jeroen,
De Keyser, Filip,
Boullart, Luc
Synovial intracellular citrullinated proteins colocalizing with peptidyl arginine deiminase as pathophysiologically relevant antigenic determinants of rheumatoid arthritis-specific humoral autoimmunity (2005)
De Rycke, Leen,
NICHOLAS, AP,
Cantaert, Tineke,
Kruithof, Elli,
ECHOLS, JD,
Vandekerckhove, Bart,
...
CARD15 polymorphisms are associated with anti-Saccharomyces Cerevisiae antibodies in Caucasian Crohn’s disease patients (2005)
Vander Cruyssen, Bert,
PEETERS, HARALD,
Hoffman, IEA,
Laukens, Debby,
Coucke, Paul,
Marichal, Denis,
...
Carriage of CARD15 gene polymorphisms and the serological marker anti-Saccharomyces cerevisiae antibodies (ASCA) are two markers for Crohn's disease (CD). Similar phenotypes have been associated with...
The presence of deiminated fibrin in the synovial membrane is not specific for rheumatoid arthritis (2004)
CHAPUY-REGAUD, S,
SEBBAG, M,
Baeten, Dominique,
CLAVEL, C,
De Keyser, Filip,
SERRE, G
Detection of major histocompatibility complex/human cartilage gp-39 complexes in rheumatoid arthritis synovitis as a specific and independent histologic marker (2004)
Baeten, Dominique,
STEENBAKKERS, PGA,
RIJNDERS, AMW,
BOOTS, AM,
Veys, Eric,
De Keyser, Filip
Case number 29: Ochronosis: synovial histopathological characteristics (2004)
Kruithof, Elli,
Baeten, Dominique,
Veys, Eric,
De Keyser, Filip,
Suykens, Stephanus,
DE WILDE, L,
...
Prediction of arthritis using a modified Kohonen mapping and case based reasoning (2004)
Wyns, Bart,
Boullart, Luc,
SETTE, S,
Baeten, Dominique,
Hoffman, Ilse,
De Keyser, Filip
Building decision tree classifiers using a Kohonen self-organizing map (2004)
Van Looy, Stijn,
Wyns, Bart,
Boullart, Luc,
Baeten, Dominique,
Hoffman, Ilse,
De Keyser, Filip
Weight analysis of a topological map to determine parameter importance (2004)
Wyns, Bart,
Van Looy, Stijn,
Boullart, Luc,
Baeten, Dominique,
Hoffman, Ilse,
De Keyser, Filip
Prediction of diagnosis in patients with early arthritis using a combined Kohonen mapping and instance-based evaluation criterion (2004)
Wyns, Bart,
SETTE, S,
Boullart, Luc,
Baeten, Dominique,
Hoffman, Ilse,
De Keyser, Filip
Diagnostic classification of spondylarthropathy and rheumatoid arthritis by synovial histopathology - A prospective study in 154 consecutive patients (2004)
Baeten, Dominique,
Kruithof, Elli,
De Rycke, Leen,
Vandooren, Bernard,
Wyns, Bart,
Boullart, Luc,
...
Rheumatoid factor and anticitrullinated protein antibodies in rheumatoid arthritis: diagnostic value, associations with radiological progression rate, and extra-articular manifestations (2004)
De Rycke, Leen,
PEENE, ISABELLE,
Hoffman, Ilse,
Kruithof, Elli,
Union, Ann,
MEHEUS, L,
...
Synovial tissue proteomics in rheumatoid arthritis and spondyloarthropathy (2004)
Tilleman, Kelly,
Van Beneden, Katrien,
De Keyser, Filip,
Veys, Eric,
Deforce, Dieter,
Elewaut, Dirk
Protein expression profiling of inflamed synovial tissue in rheumatoid arthritis, spondyloarthropathy and osteoarthritis (2004)
Tilleman, Kelly,
Dhondt, Aline,
Hoffman, Ilse,
De Keyser, Filip,
Veys, Eric,
Deforce, Dieter,
...
Identification of synovial histopathological parameters for diagnostic classification of inflammatory arthritis by SAM analysis and neural networks (2004)
Baeten, Dominique,
Wyns, Bart,
Van Looy, Stijn,
Hoffman, Ilse,
Veys, Eric,
Boullart, Luc,
...
Involvement of matrix metalloproteinases and their inhibitors in peripheral synovitis and down-regulation by tumor necrosis factor alpha blockade in spondylarthropathy (2004)
Vandooren, Bernard,
Kruithof, Elli,
YU, DTY,
RIHL, M,
GU, JR,
De Rycke, Leen,
...
The presence of CARD15 polymorphisms is linked with higher ASCA titers in Crohn's disease (2004)
Peeters, Harald,
Vander Cruyssen, Bert,
LAUKENS, D,
COUCKE, P,
Hoffman, Ilse,
De Keyser, Filip,
...
Association of CD163+ macrophages and local production of soluble CD163 with decreased lymphocyte activation in spondylarthropathy synovitis (2004)
Baeten, Dominique,
MOLLER, HJ,
DELANGHE, J,
Veys, Eric,
MOESTRUP, SK,
De Keyser, Filip
Radiological sacroiliitis is linked with CARD15 gene polymorphisms in patients with Crohn's disease (2004)
Vander Cruyssen, Bert,
Peeters, Harald,
LAUKENS, D,
COUCKE, P,
Mielants, Herman,
De Vos, Martine,
...
Serum levels of matrix metalloproteinase 3 and macrophage colony-stimulating factor 1 correlate with disease activity in ankylosing spondylitis (2004)
YANG, CH,
GU, JR,
RIHL, M,
Baeten, Dominique,
HUANG, F,
ZHAO, MS,
...
Specific antinuclear antibodies are associated with clinical features in systemic lupus erythematosus (2004)
Hoffman, Ilse,
PEENE, ISABELLE,
MEHEUS, L,
HUIZINGA, TWJ,
CEBECAUER, L,
ISENBERG, D,
...
History and diagnostic value of antibodies to citrullinated proteins in rheumatoid arthritis (2004)
PEENE, ISABELLE,
De Rycke, Leen,
Baeten, Dominique,
Hoffman, Ilse,
Veys, Eric,
De Keyser, Filip
Tumour necrosis factor alpha independent disease mechanisms in rheumatoid arthritis: a histopathological study on the effect of infliximab on rheumatoid nodules (2004)
Baeten, Dominique,
De Keyser, Filip,
Veys, Eric,
THEATE, Y,
HOUSSIAU, FA,
DUREZ, P
Technical validation of cDNA based microarray as screening technique to identify candidate genes in synovial tissue biopsy specimens from patients with spondyloarthropathy (2004)
RIHL, M,
Baeten, Dominique,
SETA, N,
GU, J,
De Keyser, Filip,
Veys, Eric,
...
False positivity of rheumatoid factor and antibodies to citrullinated peptides in systemic lupus erythematosus (2004)
Hoffman, Ilse,
PEENE, ISABELLE,
Union, Ann,
MEHEUS, L,
HUIZINGA, T,
CEBECAUER, L,
...
Diagnostic performance and predictive value of serum markers for the diagnosis of rheumatoid arthritis (2004)
Hoffman, Ilse,
PEENE, ISABELLE,
Union, Ann,
MEHEUS, L,
DE CLERCQ, L,
SCHATTEMAN, L,
...
Differential expression and response to infliximab treatment of specific macrophage subsets in inflammatory synovitis (2004)
De Rycke, Leen,
Baeten, Dominique,
FOELL, D,
Kruithof, Elli,
Veys, Eric,
ROTH, J,
...
The effect of infliximab on skin lesions in a patient with scleroderma (CREST) (2004)
De Rycke, Leen,
Baeten, Dominique,
Van Den Bosch, Filip,
Mielants, Herman,
De Keyser, Filip,
Veys, Eric
Serum MRP8/MRP14 as a biomarker for inflammation in autoimmune arthritis (2004)
De Rycke, Leen,
Baeten, Dominique,
FOELL, D,
Kruithof, Elli,
Veys, Eric,
ROTH, J,
...
Radiological sacroiliitis, a hallmark of spondylitis, is linked with CARD15 gene polymorphisms in patients with Crohn's disease (2004)
PEETERS, HARALD,
Vander Cruyssen, Bert,
Laukens, Debby,
Coucke, Paul,
MARICHAL, DENIS,
VAN DEN BERGHE, MARTINA,
...
Structure-modifying capacity of anti-tumour necrosis factor-alpha therapy in Ankylosing spondylitis (2004)
De Keyser, Filip,
Baeten, Dominique,
Van Den Bosch, Filip,
KRUITHOF, ELLI,
VERBRUGGEN, G,
Mielants, Herman,
...
Antinuclear antibodies following Infliximab treatment in patients with rheumatoid arthritis or spondylarthropathy (2003)
De Rycke, Leen,
Kruithof, Elli,
VAN DAMME, NANCY,
Hoffman, Ilse,
Van Den Bosch, Filip,
...
Systematic safety follow-up in a cohort of 107 patients with spondylarthropathy treated with Infliximab: a new perspective of the role of host defence in the pathogenesis of the disease? (2003)
Baeten, Dominique,
Kruithof, Elli,
Van Den Bosch, Filip,
HERSSENS, MARIANNE,
Mielants, Herman,
...
Infliximab in patients who have spondyloarthropathy: clinical efficacy, safety and biological immunomodulation (2003)
De Keyser, Filip,
Baeten, Dominique,
Van Den Bosch, Filip,
Kruithof, Elli,
Mielants, Herman,
Veys, Eric
Infliximab in patients who have spondyloarthropathy: clinical efficacy, safety, and biological immunomodulation (2003)
De Keyser, Filip,
Baeten, Dominique,
Van Den Bosch, Filip,
Kruithof, Elli,
Mielants, Herman,
Veys, Eric
Systematic safety follow up in a cohort of 107 patients with spondyloarthropathy treated with infliximab: a new perspective on the role of host defence in the pathogenesis of the disease? (2003)
Baeten, Dominique,
Kruithof, Elli,
Van Den Bosch, Filip,
HERSSENS, A,
Mielants, Herman,
...
Localization of MHC class II/human cartilage glycoprotein-39 complexes in synovia of rheumatoid arthritis patients using complex-specific monoclonal antibodies (2003)
STEENBAKKERS, PGA,
Baeten, Dominique,
ROVERS, E,
Veys, Eric,
RIJNDERS, AWM,
MEIJERINK, J,
...
Anti-Saccharomyces cerevisiae IgA antibodies are raised in ankylosing spondylitis and undifferentiated spondyloarthropathy (2003)
Hoffman, Ilse,
Demetter, Pieter,
Peeters, Marc,
De Vos, Martine,
Mielants, Herman,
Veys, Eric,
...
Antinuclear antibodies following infliximab treatment in patients with rheumatoid arthritis or spondylarthropathy (2003)
De Rycke, Leen,
Kruithof, Elli,
VAN DAMME, NANCY,
Hoffman, Ilse,
Van Den Bosch, Filip,
...
The use of neural network algorithms for the classification of undifferentiated arthritis by synovial histopathology (2003)
Baeten, Dominique,
Wyns, Bart,
Hoffman, Ilse,
SETTE, S,
Boullart, Luc,
De Keyser, Filip
Peptidylarginine deiminase isoforms expressed in the synovial membrane of rheumatoid arthritis patients (2003)
CHAPUY-REGAUD, S,
SEBBAG, M,
NACHAT, R,
Baeten, Dominique,
FOULQUIER, V,
SIMON, M,
...
Presence of anti-RNP-A and anti-RNP-C antibodies is inversely associated with renal symptoms of systemic lupus erythematosus (2003)
HOFFMAN, I,
PEENE, ISABELLE,
MEHEUS, L,
DE BOSSCHERE, K,
HULSTAERT, F,
HUIZINGA, TWJ,
...
Changes in rheumatoid factor reflect the inflammatory response (CRP and ESR) to infliximab treatment (2003)
De Rycke, Leen,
Kruithof, Elli,
VAN DAMME, NANCY,
Hoffman, Ilse,
Van Den Bosch, Filip,
Veys, Eric,
...
Localisation of MHC Class II/HC gp-39 complexes in synovia of rheumatoid arthritis patients using complex-specific monoclonal antibodies (2003)
Baeten, Dominique,
STEENBAKKERS, PGA,
ROVERS, E,
Veys, Eric,
RIJNDERS, AMW,
MEIJERINK, J,
...
Effect of infliximab on matrix metalloprotelinase (MMP)-1,-2,-3 and tissue inhibitors of matrix metalloproteinases (TIMP)-1,-2 in spondyloarthropathy (SpA) synovitis (2003)
Vandooren, Bernard,
Kruithof, Elli,
De Keyser, Filip,
YU, DTY,
Veys, Eric,
Baeten, Dominique
Serum MRP 8/14 is an inflammatory marker for chronic arthritis, partially originating from the inflamed joint (2003)
De Rycke, Leen,
Baeten, Dominique,
FOELL, D,
Veys, Eric,
De Keyser, Filip,
ROTH, J
Microarray data mining uncovers neurotrophins and their receptors as potential mediators in spondyloarthritis (SpA) (2003)
RIHL, M,
KUIPERS, JG,
De Keyser, Filip,
Veys, Eric,
ZEIDLER, H,
YU, DTY,
...
Microarrays uncover serum elisa levels of metalloproteinase-3 (MMP3) as a useful parameter to measure disease activity in anky-losing spondylitis (AS) (2003)
HUANG, F,
ZHAO, MS,
YANG, CH,
ZHANG, HW,
GU, JR,
RIHL, M,
...
Rheumatoid factor and anti-citrullinated peptide antibodies in rheumatoid arthritis: Diagnostic value and association with radiological progression (2003)
De Rycke, Leen,
PEENE, ISABELLE,
Hoffman, Ilse,
Kruithof, Elli,
Union, Ann,
MEHEUS, L,
...
Crohn's disease patients with CARD15 variants have higher risk of developing axial joint involvement (2003)
De Vos, Martine,
Peeters, Harald,
Vander Cruyssen, Bert,
LAUKENS, D,
MARICHAL, D,
VANDENBERGHE, M,
...
CARD15 mutations in patients with spondyloarthropathy are linked with disease progression and evolution to Crohn's disease (2003)
De Vos, Martine,
LAUKENS, D,
MARICHAL, DENIS,
Peeters, Harald,
Elewaut, Dirk,
...
The use of neural network algorithms for the classification of undifferentiated arthritis by synovial histopathology (2003)
Baeten, Dominique,
Wyns, Bart,
Hoffman, Ilse,
SETTE, S,
Boullart, Luc,
De Keyser, Filip
Myeloid-related protein (MRP) 8 and MRP 14 in rheumatoid arthritis and spondyloarthropathy (2003)
De Rycke, Leen,
Baeten, Dominique,
FOELL, D,
Veys, Eric,
De Keyser, Filip,
ROTH, J
The diagnostic value of synovial histopathology in undifferentiated inflammatory arthritis: a prospective study in 154 consecutive patients (2003)
Baeten, Dominique,
Kruithof, Elli,
Hoffman, Ilse,
De Rycke, Leen,
Vandooren, Bernard,
Veys, Eric,
...
Local production of soluble CD163 in the spondyloarthropathic joint (2003)
Baeten, Dominique,
MOLLER, HJ,
DELANGHE, J,
Veys, Eric,
MOESTRUP, SK,
De Keyser, Filip
Cutaneous polyarteritis nodosa: A distinct entity (2003)
PEENE, ISABELLE,
De Rycke, Leen,
Praet, Marleen,
Veys, Eric,
Naeyaert, Jean,
De Keyser, Filip
Prediction of arthritis using a modified Kohonen mapping and case based learning (2003)
Boullart, Luc,
Sette, Stefan,
Wyns, Bart,
Baeten, Dominique,
Hoffman, Ilse,
De Keyser, Filip
Macrophages expressing the scavenger receptor CD163: a link between immune alterations of the gut and synovial inflammation in spondyloarthropathy. (2002)
Baeten, Dominique,
Demetter, Pieter,
Cuvelier, Claude,
Kruithof, Elli,
Van Damme, Nancy,
De Vos, Martine,
...
Increase in lymphoid follicles and leukocyte adhesion molecules emphasizes a role for the gut in spondyloarthropathy pathogenesis. (2002)
Demetter, Pieter,
Van Huysse, Jacques,
De Keyser, Filip,
Van Damme, Nancy,
VERBRUGGEN, G,
Mielants, Herman,
...
Gut inflammation and spondyloarthropathies. (2002)
De Keyser, Filip,
Baeten, Dominique,
Mielants, Herman,
De Vos, Martine,
Cuvelier, Claude,
Veys, Eric
The cutting edge of spondyloarthropathy research in the millennium. (2002)
GRANFORS, K,
MARKER-HERMAN, E,
De Keyser, Filip,
KHAN, MA,
Veys, Eric,
YU, D
A 588-gene microarray analysis of the peripheral blood mononuclear cells of spondyloarthropathy patients. (2002)
GU, J,
MARKER-HERMANN, E,
Baeten, Dominique,
TSAI, WC,
GLADMAN, D,
XIONG, M,
...
Clues to pathogenesis of spondyloarthropathy derived from synovial fluid mononuclear cell gene expression profiles. (2002)
GU, J,
RIHL, M,
MARKER-HERMANN, E,
Baeten, Dominique,
KUIPERS, JG,
SONG, YW,
...
Successful treatment with Infliximab in a patient with therapy-resistant spondyloarthropathy-related uveitis. (2002)
Kruithof, Elli,
KESTELYN, PH,
ELEWAUT, C,
Elewaut, Dirk,
Mielants, Herman,
...
Repeated infusions of infliximab, a chimeric anti-TNF alpha monoclonal antibody, in patients with active spondyloarthropathy: one year follow up. (2002)
Kruithof, Elli,
Baeten, Dominique,
HERSSENS, A,
De Keyser, Filip,
Mielants, Herman,
...
Anti-Ro52 reactivity is an independent and additional serum marker in connective tissue disease. (2002)
Peene, Isabelle,
MEHEUS, L,
DE KEYSER, S,
HUMBEL, R,
Veys, Eric,
De Keyser, Filip
Identification of citrullinated rheumatoid arthritis-specific epitopes in natural filaggrin relevant for antifilaggrin autoantibody detection by line immunoassay. (2002)
Union, Ann,
MEHEUS, L,
HUMBEL, RL,
CONRAD, K,
STEINER, G,
MOEREELS, H,
...
Randomized double-blind comparison of chimeric monoclonal antibody to tumor necrosis factor alpha (infliximab) versus placebo in active spondylarthropathy. (2002)
Kruithof, Elli,
Baeten, Dominique,
HERSSENS, A,
De Keyser, Filip,
Mielants, Herman,
...
Dynamic T cell receptor clonotype changes in synovial tissue of patients with early rheumatoid arthritis: Effects of treatment with cyclosporin A (Neoral (R)). (2002)
VANDERBORGHT, A,
De Keyser, Filip,
GEUSENS, P,
DE BACKER, M,
MALAISE, M,
Baeten, Dominique,
...
Specific presence of intracellular citrullinated proteins in rheumatoid arthritis synovium - Relevance to antifilaggrin autoantibodies. (2001)
Baeten, Dominique,
Peene, Isabelle,
Union, Ann,
MEHEUS, L,
SEBBAG, M,
SERRE, G,
...
Impaired Th1 cytokine production in spondyloarthropathy is restored by anti-TNF alpha. (2001)
Baeten, Dominique,
Van Damme, Nancy,
Kruithof, Elli,
De Vos, Martine,
Mielants, Herman,
...
Immunomodulatory effects of anti-tumor necrosis factor alpha therapy on synovium in spondylarthropathy - Histologic findings in eight patients from an open-label pilot study. (2001)
Baeten, Dominique,
Kruithof, Elli,
Demetter, Pieter,
Van Damme, Nancy,
Cuvelier, Claude,
...
The stress protein BiP is overexpressed and is a major B and T cell target in rheumatoid arthritis. (2001)
BLASS, S,
Union, Ann,
RAYMACKERS, J,
SCHUMANN, F,
UNGETHUM, U,
MULLER-STEINBACH, S,
...
Gut mucosal T cell lines from ankylosing spondylitis patients are enriched with alpha E beta 7 integrin. (2001)
Van Damme, Nancy,
Elewaut, Dirk,
Baeten, Dominique,
Demetter, Pieter,
Cuvelier, Claude,
VERBRUGGEN, G,
...
Flow cytometric analysis of gut mucosal lymphocytes supports an impaired Th1 cytokine profile in spondyloarthropathy. (2001)
Van Damme, Nancy,
De Vos, Martine,
Baeten, Dominique,
Demetter, Pieter,
Mielants, Herman,
VERBRUGGEN, G,
...
The proportion of Th1 cells, which prevail in gut mucosa, is decreased in inflammatory bowel syndrome. (2001)
Van Damme, Nancy,
De Keyser, Filip,
Demetter, Pieter,
Baeten, Dominique,
Mielants, Herman,
VERBRUGGEN, G,
...
New treatment options in spondyloarthropathies: increasing evidence for significant efficacy of anti-tumor necrosis factor therapy. (2001)
BRAUN, J,
De Keyser, Filip,
BRANDT, J,
Mielants, Herman,
SIEPER, J,
Veys, Eric
Treatment of active spondyloarthropathy with infliximab, the chimeric monoclonal antibody to tumour necrosis factor alpha. (2001)
Van Den Bosch, Filip,
Baeten, Dominique,
Kruithof, Elli,
De Keyser, Filip,
Mielants, Herman,
Veys, Eric
Effects of anti-tumor necrosis factor alpha on synovium in patients with spondylarthropathy: Comment on the article by Baeten et al - Reply. (2001)
Baeten, Dominique,
Kruithof, Elli,
Van Den Bosch, Filip,
Mielants, Herman,
Veys, Eric,
De Keyser, Filip
Spondyloarthropathy is underestimated in inflammatory bowel disease: Prevalence and HLA association. (2000)
De Vlam, Kurt,
Mielants, Herman,
Cuvelier, Claude,
De Keyser, Filip,
Veys, Eric,
De Vos, Martine
Immune-mediated pathology following hepatitis B vaccination. Two cases of polyarteritis nodosa and one case of pityriasis rosea-like drug eruption. (2000)
De Keyser, Filip,
NAEYAERT, JM,
HINDRICKX, P,
Elewaut, Dirk,
VERPLANCKE, P,
Peene, Isabelle,
...
Comparative study of the synovial histology in rheumatoid arthritis, spondyloarthropathy, and osteoarthritis: influence of disease duration and activity. (2000)
Baeten, Dominique,
Demetter, Pieter,
Cuvelier, Claude,
Kruithof, Elli,
Van Damme, Nancy,
...
Chemical agents and enzymes used for the extraction of gut lymphocytes influence flow cytometric detection of T cell surface markers. (2000)
Van Damme, Nancy,
Baeten, Dominique,
De Vos, Martine,
Demetter, Pieter,
Elewaut, Dirk,
Mielants, Herman,
...
Subclinical gut inflammation in spondyloarthropathy patients is associated with upregulation of the E-cadherin/catenin complex. (2000)
Demetter, Pieter,
Baeten, Dominique,
De Keyser, Filip,
De Vos, Martine,
Van Damme, Nancy,
VERBRUGGEN, G,
...
Focal up-regulation of E-cadherin-catenin complex in inflamed bowel mucosa but reduced expression in ulcer associated cell lineage. (2000)
Demetter, Pieter,
De Vos, Martine,
Van Damme, Nancy,
Baeten, Dominique,
Elewaut, Dirk,
VERMEULEN, S,
...
The C-terminal RG dipeptide repeats of the spliceosomal Sm proteins D1 and D3 contain symmetrical dimethylarginines, which form a major B-cell epitope for anti-Sm autoantibodies. (2000)
BRAHMS, H,
RAYMACKERS, J,
Union, Ann,
De Keyser, Filip,
MEHEUS, L,
LUHRMANN, R
Human cartilage gp-39+, CD16+monocytes in peripheral blood and synovium - Correlation with joint destruction in rheumatoid arthritis. (2000)
Baeten, Dominique,
BOOTS, AMH,
STEENBAKKERS, PGA,
Elewaut, Dirk,
BOS, E,
VERHEIJDEN, GFM,
...
Sensitivity of the HEp-2000 substrate for the detection of Anti-SSA/Ro60 antibodies. (2000)
Peene, Isabelle,
VAN AEL, W,
VANDENBOSSCHE, M,
VERVAET, T,
Veys, Eric,
De Keyser, Filip
Polyarteritis nodosa mimicking polymyalgia rheumatica. (1999)
Kruithof, Elli,
Elewaut, Dirk,
Naeyaert, Jean,
Praet, Marleen,
Mielants, Herman,
Veys, Eric,
...
Multicenter validation of recombinant, natural and synthetic antigens used in a single multiparameter assay for the detection of specific anti-nuclear autoantibodies in connective tissue disorders. (1999)
MEHEUS, L,
VAN VENROOIJ, WJ,
WIIK, A,
CHARLES, PJ,
TZIOUFAS, AG,
MEYER, O,
...
Anti-perinuclear factor compared with the so called "antikeratin" antibodies and antibodies to human epidermis filaggrin, in the diagnosis of arthritides. (1999)
VINCENT, C,
De Keyser, Filip,
MASSON-BESSIERE, C,
SEBBAG, M,
Veys, Eric,
SERRE, G
Distinctive activated cellular subsets in colon from patients with Crohn's disease and ulcerative colitis. (1998)
Elewaut, Dirk,
De Keyser, Filip,
Cuvelier, Claude,
LAZAROVITS, AI,
Mielants, Herman,
VERBRUGGEN, G,
...
A comparative phenotypical analysis of rheumatoid nodules and rheumatoid synovium with special reference to adhesion molecules and activation markers. (1998)
Elewaut, Dirk,
De Keyser, Filip,
DE WEVER, N,
Baeten, Dominique,
Van Damme, Nancy,
VERBRUGGEN, G,
...
Enrichment of T cells carrying 137 integrins in inflamed synovial tissue from patients with early spondyloarthropathy, compared to rheumatoid arthritis. (1998)
Elewaut, Dirk,
De Keyser, Filip,
LAZAROVITS, AI,
De Vos, Martine,
Cuvelier, Claude,
...
Altered expression of alpha E beta 7 integrin on intra-epithelial and lamina propria lymphocytes in patients with Crohn's disease. (1998)
Elewaut, Dirk,
Van Damme, Nancy,
De Keyser, Filip,
BAETEN, D,
De Paepe, Pascale,
Van Vlierberghe, Hans,
...
Bowel inflammation and the spondyloarthropathies. (1998)
De Keyser, Filip,
Elewaut, Dirk,
De Vos, Martine,
De Vlam, Kurt,
Cuvelier, Claude,
Mielants, Herman,
...
Upregulation of E-cadherin and associated molecules (a-, ß- and y-catenins) in inflamed bowel mucosa (1998)
Demetter, Pieter,
De Vos, Martine,
Van Damme, Nancy,
Baeten, Dominique,
CESMELI, E,
Elewaut, Dirk,
...
Increased expression of E 7 integrin in uninflamed mucosa of patients with spondyloarthropathy (1998)
Elewaut, Dirk,
Van Damme, Nancy,
Baeten, Dominique,
Demetter, Pieter,
SAS, S,
De Vos, Martine,
...
Isolation of colonie mucosal lamina propria and intra-epithelial lymphocytes : mechanical versus enzymatic isolation (1998)
Van Damme, Nancy,
Baeten, Dominique,
De Keyser, Filip,
Demetter, Pieter,
Elewaut, Dirk,
NECKEBROEK, M,
...
Effects of chemical agents and enzymes on the detection of lymphocyte surface markers. (1998)
Van Damme, Nancy,
Baeten, Dominique,
De Vos, Martine,
Demetter, Pieter,
Elewaut, Dirk,
Mielants, Herman,
...
Selection of self-reactive peptides within human aggrecan by use of a HLA-DRB1*0401 peptide binding motif. (1997)
BOOTS, AMH,
VERHEIJDEN, GFM,
SCHONINGH, R,
VAN STAVEREN, CJ,
BOS, E,
Elewaut, Dirk,
...
Human cartilage glycoprotein-39 as a candidate autoantigen in rheumatoid arthritis. (1997)
VERHEIJDEN, GFM,
RIJNDERS, AWM,
BOS, E,
DEROO, CJJC,
VANSTAVEREN, CJ,
MILTENBURG, AMM,
...
Dominant T cell receptor rearrangements in interleukin 2 expanded lymphocytes from rheumatoid nodules suggest antigen driven T cell activation in situ. (1997)
De Keyser, Filip,
Elewaut, Dirk,
OVERMEERGRAUS, JPM,
VANDENBROEK, P,
RIJNDERS, AWM,
Veys, Eric
Altered expression of ocEß7 integrin on intra-epithelial and lamina propria lymphocytes in patients with Crohn's disease. (1997)
Elewaut, Dirk,
Van Damme, Nancy,
De Keyser, Filip,
Baeten, Dominique,
De Paepe, Peter,
Van Vlierberghe, Hans,
...
Etiological factors and underlying conditions in patients with leucocytoclastic vasculitis. (1996)
GYSELBRECHT, L,
De Keyser, Filip,
ONGENAE, K,
Naeyaert, Jean,
Praet, Marleen,
Veys, Eric
Polyarteritis nodosa and the antiphospholipid syndrome. (1996)
Schoonjans, Renaat,
VANVLEM, B,
WEYERS, S,
De Keyser, Filip,
Praet, Marleen,
Versieck, Jacques,
...
THE ROLE OF T-CELLS IN RHEUMATOID-ARTHRITIS. (1995)
De Keyser, Filip,
Elewaut, Dirk,
VERMEERSCH, J,
DEWEVER, N,
Cuvelier, Claude,
Veys, Eric
An optimized method for routine HLA-B27 screening using flow cytometry. (1994)
HULSTAERT, F,
ALBRECHT, J,
HANNET, I,
LANCASTER, P,
BUCHNER, L,
KUNZ, J,
...
Classificatie en histopathologie van vasculitiden. (1994)
Praet, Marleen,
De Keyser, Filip,
NAEYAERT, J,
KEPS, J,
Vanholder, Raymond,
De Bleecker, Jan,
...
Vasculitis : een morfologische benadering van een multidisciplinair probleem (1994)
Praet, Marleen,
De Keyser, Filip,
Naeyaert, Jean,
Kips, Johan,
Vanholder, Raymond,
Pauwels, Romain,
...
INTERLABORATORY VARIABILITY OF THE ANTIPERINUCLEAR FACTOR (APF) TEST FOR RHEUMATOID-ARTHRITIS. (1993)
FELTKAMP, TEW,
BERTHELOT, JM,
BOERBOOMS, AMT,
GEERTZEN, HGM,
HOET, R,
De Keyser, Filip,
...
T cell receptor Vbeta usage in rheumatoid nodules - marked oligoclonality among DL-2 expanded lymphocytes. (1993)
De Keyser, Filip,
VERBRUGGEN, G,
Veys, Eric,
Cuvelier, Claude,
Malfait, Anne-Marie,
Benoit, Dominique,
...
Detection and identification of antinuclear autoantibodies in the serum of normal blood donors. (1993)
DEVLAM, K,
De Keyser, Filip,
VERBRUGGEN, G,
VANDENBOSSCHE, M,
VANNEUVILLE, B,
DHAESE, D,
...
T-CELL RECEPTOR EXPRESSION IN PATIENTS WITH RHEUMATIC DISEASES. (1992)
De Keyser, Filip,
Benoit, Dominique,
Elewaut, Dirk,
LEROY, B,
MALFAIT, AM,
VERBRUGGEN, G,
...
T-cell receptor expression in patients with rheumatic diseases (1992)
De Keyser, Filip,
Benoit, Dominique,
Elewaut, Dirk,
LEROY, B,
Malfait, Anne-Marie,
VERBRUGGEN, G,
...
Infiltration of the synovial membrane with macrophage subsets and polymorphonuclear cells reflects global disease activity in spondyloarthropathy
Baeten, Dominique,
Kruithof, Elli,
De Rycke, Leen,
Boots, Anemieke M,
Mielants, Herman,
Veys, Eric M,
...
Considering the relation between synovial inflammation and global disease activity in rheumatoid arthritis (RA) and the distinct but heterogeneous histology of spondyloarthropathy (SpA) synovitis,...
Synovial histopathology of psoriatic arthritis, both oligo- and polyarticular, resembles spondyloarthropathy more than it does rheumatoid arthritis
Kruithof, Elli,
Baeten, Dominique,
De Rycke, Leen,
Vandooren, Bernard,
Foell, Dirk,
Roth, Johannes,
...
At present only few biological data are available to indicate whether psoriatic arthritis (PsA) is part of the spondyloarthropathy (SpA) concept, whether it is a separate disease entity or a...
Tumor necrosis factor-α blockade in ankylosing spondylitis: a potent but expensive anti-inflammatory treatment or true disease modification?
Van Den Bosch, Filip,
De Keyser, Filip,
Mielants, Herman,
Veys, Eric M
Blocking tumor necrosis factor-α either with monoclonal antibodies or with soluble receptor constructs has been proven to be effective with an acceptable safety profile in patients with rheumatoid...
DAS28 best reflects the physician's clinical judgment of response to infliximab therapy in rheumatoid arthritis patients: validation of the DAS28 score in patients under infliximab treatment
Vander Cruyssen, Bert,
Van Looy, Stijn,
Wyns, Bart,
Westhovens, Rene,
Durez, Patrick,
Van Den Bosch, Filip,
...
This study is based on an expanded access program in which 511 patients suffering from active refractory rheumatoid arthritis (RA) were treated with intravenous infusions of infliximab (3...
Infiltration of the synovial membrane with macrophage subsets and polymorphonuclear cells reflects global disease activity in spondyloarthropathy
Baeten, Dominique,
Kruithof, Elli,
De Rycke, Leen,
Boots, Anemieke M,
Mielants, Herman,
Veys, Eric M,
...
Considering the relation between synovial inflammation and global disease activity in rheumatoid arthritis (RA) and the distinct but heterogeneous histology of spondyloarthropathy (SpA) synovitis,...
Synovial histopathology of psoriatic arthritis, both oligo- and polyarticular, resembles spondyloarthropathy more than it does rheumatoid arthritis
Kruithof, Elli,
Baeten, Dominique,
De Rycke, Leen,
Vandooren, Bernard,
Foell, Dirk,
Roth, Johannes,
...
At present only few biological data are available to indicate whether psoriatic arthritis (PsA) is part of the spondyloarthropathy (SpA) concept, whether it is a separate disease entity or a...
Tumor necrosis factor-α blockade in ankylosing spondylitis: a potent but expensive anti-inflammatory treatment or true disease modification?
Van Den Bosch, Filip,
De Keyser, Filip,
Mielants, Herman,
Veys, Eric M
Blocking tumor necrosis factor-α either with monoclonal antibodies or with soluble receptor constructs has been proven to be effective with an acceptable safety profile in patients with rheumatoid...
DAS28 best reflects the physician's clinical judgment of response to infliximab therapy in rheumatoid arthritis patients: validation of the DAS28 score in patients under infliximab treatment
Vander Cruyssen, Bert,
Van Looy, Stijn,
Wyns, Bart,
Westhovens, Rene,
Durez, Patrick,
Van Den Bosch, Filip,
...
This study is based on an expanded access program in which 511 patients suffering from active refractory rheumatoid arthritis (RA) were treated with intravenous infusions of infliximab (3...
Diagnostic value of anti-human citrullinated fibrinogen ELISA and comparison with four other anti-citrullinated protein assays
Vander Cruyssen, Bert,
Cantaert, Tineke,
Nogueira, Leonor,
Clavel, Cyril,
De Rycke, Leen,
Dendoven, Amélie,
...
We studied the diagnostic performance of the anti-human citrullinated fibrinogen antibody (AhFibA) ELISA for rheumatoid arthritis (RA) in a consecutive cohort (population 1) and evaluated the...
Four-year follow-up of infliximab therapy in rheumatoid arthritis patients with long-standing refractory disease: attrition and long-term evolution of disease activity
Cruyssen, Bert Vander,
Van Looy, Stijn,
Wyns, Bart,
Westhovens, Rene,
Durez, Patrick,
Van Den Bosch, Filip,
...
Although there is strong evidence supporting the short-term efficacy and safety of anti-tumour necrosis factor-α agents, few studies have examined the long-term effects. We evaluated 511 patients...
Response to the commentary 'Pooled indices to measure rheumatoid arthritis activity: a good reflection of the physician's mind'
Vander Cruyssen, Bert,
Durez, Patrick,
Westhovens, Rene,
Vastesaeger, Nathan,
Geldhof, Anja,
De Keyser, Filip
Proinflammatory cytokine production and cell adhesion molecule expression compared in rheumatoid nodules and synovial membranes : comment on the article by Wikaningrum et al. Arthritis Rheum. (Letter), 42, 1999, 1067.
Elewaut, Dirk,
De Keyser, Filip,
VERBRUGGEN, G,
VEYS E, M
Prediction of diagnosis in patients with early arthritis using a modified Kohonen mapping in combination with a case based learning evaluation criterion
Boullart, Luc,
SETTE, S,
Wyns, Bart,
Baeten, Dominique,
Hoffman, Ilse,
De Keyser, Filip