Uptake of particulate vaccine adjuvants by dendritic cells activates the NALP3 inflammasome
Sharp, Fiona A., Ruane, Darren, Claass, Benjamin, Creagh, Emma, Harris, James, Malyala, Padma, ...
Many currently used and candidate vaccine adjuvants are particulate in nature, but their mechanism of action is not well understood. Here, we show that particulate adjuvants, including biodegradable...