Frédéric Simard

Trends in DDT and pyrethroid resistance in Anopheles gambiaes.s. populations from urban and agro-industrial settings in southern Cameroon (2009)

Nwane, Philippe, Etang, Josiane, Chouaibou, Mouhamadou, Toto, Jean, Kerah-Hinzoumbé, Clément, Mimpfoundi, Rémy, ...

Abstract Background Pyrethroid insecticides are widely used for insect pest control in Cameroon. In certain insect species, particularly the malaria vector Anopheles gambiae , resistance to this...

Malaria vectors and transmission dynamics in Goulmoun, a rural city in south-western Chad (2009)

Kerah-Hinzoumbé, Clément, Péka, Mallaye, Antonio-Nkondjio, Christophe, Donan-Gouni, Issa, Awono-Ambene, Parfait, Samè-Ekobo, Albert, ...

Abstract Background Knowledge of some baseline entomological data such as Entomological Inoculation Rates (EIR) is crucially needed to assess the epidemiological impact of malaria control activities...

Ecological niche partitioning between Anopheles gambiaemolecular forms in Cameroon: the ecological side of speciation (2009)

Simard, Frédéric, Ayala, Diego, Kamdem, Guy, Pombi, Marco, Etouna, Joachim, Ose, Kenji, ...

Abstract Background Speciation among members of the Anopheles gambiae complex is thought to be promoted by disruptive selection and ecological divergence acting on sets of adaptation genes protected...

Living at the edge: biogeographic patterns of habitat segregation conform to speciation by niche expansion in Anopheles gambiae (2009)

Costantini, Carlo, Ayala, Diego, Guelbeogo, Wamdaogo M, Pombi, Marco, Some, Corentin Y, Bassole, Imael HN, ...

Abstract Background Ongoing lineage splitting within the African malaria mosquito Anopheles gambiae is compatible with ecological speciation, the evolution of reproductive isolation by divergent...

Insecticide resistance in Anopheles gambiaefrom south-western Chad, Central Africa (2008)

Kerah-Hinzoumbé, Clément, Péka, Mallaye, Nwane, Philippe, Donan-Gouni, Issa, Etang, Josiane, Samè-Ekobo, Albert, ...

Abstract Background Indoor residual spraying and insecticide-treated nets (ITN) are essential components of malaria vector control in Africa. Pyrethroids are the only recommended compounds for nets...

Insertion polymorphisms of SINE200retrotransposons within speciation islands of Anopheles gambiaemolecular forms (2008)

Santolamazza, Federica, Mancini, Emiliano, Simard, Frédéric, Qi, Yumin, Tu, Zhijian, Della Torre, Alessandra

Abstract Background SINEs (Short INterspersed Elements) are homoplasy-free and co-dominant genetic markers which are considered to represent useful tools for population genetic studies, and could...

Population structure of the malaria vector Anopheles mouchetiin the equatorial forest region of Africa (2008)

Antonio-Nkondjio, Christophe, Ndo, Cyrille, Kengne, Pierre, Mukwaya, Louis, Awono-Ambene, Parfait, Fontenille, Didier, ...

Abstract Background Anopheles moucheti is a major malaria vector in forested areas of Africa. However, despite its important epidemiological role, it remains poorly known and insufficiently studied....

SNP discovery and molecular evolution in Anopheles gambiae, with special emphasis on innate immune system (2008)

Cohuet, Anna, Krishnakumar, Sujatha, Simard, Frédéric, Morlais, Isabelle, Koutsos, Anastasios, Fontenille, Didier, ...

Abstract Background Anopheles innate immunity affects Plasmodium development and is a potential target of innovative malaria control strategies. The extent and distribution of nucleotide diversity in...

Gene Flow Between Domestic and Sylvan Populations of Aedes aegypti (Diptera: Culicidae) in North Cameroon (2008)

Christophe Paupy, Cécile Brengues, Basile Kamgang, Jean-Pierre Hervé, Didier Fontenille, Frédéric Simard

Polymorphisms at eight microsatellite loci and a fragment of the mitochondrial DNA (mtDNA)-ND4 gene were surveyed in Aedes aegypti (L.) (Diptera: Culicidae) populations collected from six localities...

PCR-based karyotyping of Anopheles gambiaeinversion 2Rjidentifies the BAMAKO chromosomal form (2007)

Coulibaly, Mamadou B, Pombi, Marco, Caputo, Beniamino, Nwakanma, Davis, Jawara, Musa, Konate, Lassana, ...

Abstract Background The malaria vector Anopheles gambiae is polymorphic for chromosomal inversions on the right arm of chromosome 2 that segregate nonrandomly between assortatively mating populations...

Design of a Two-level Adaptive Multi-Agent System for Malaria Vectors driven by an ontology (2007)

Koum, Guillaume, Yekel, Augustin, Ndifon, Bengyella, Etang, Josiane, Simard, Frédéric

Abstract Background The understanding of heterogeneities in disease transmission dynamics as far as malaria vectors are concerned is a big challenge. Many studies while tackling this problem don't...

Efficacy of bifenthrin-impregnated bednets against Anopheles funestusand pyrethroid-resistant Anopheles gambiaein North Cameroon (2006)

Chouaibou, Mouhamadou, Simard, Frédéric, Chandre, Fabrice, Etang, Josiane, Darriet, Frédéric, Hougard, Jean-Marc

Abstract Background Recent field studies indicated that insecticide-treated bednets (ITNs) maintain their efficacy despite a high frequency of the knock-down resistance ( kdr ) gene in Anopheles...

Species and Populations of the Anopheles gambiae Complex in Cameroon with Special Emphasis on Chromosomal and Molecular Forms of Anopheles gambiae s.s. (2005)

Charles Wondji, Frédéric Simard, Vincenzo Petrarca, Josiane Etang, Federica Santolamazza, Alessandra Della Torre, ...

We studied the geographical distribution of species, chromosomal, and molecular forms of the Anopheles gambiae Giles (Diptera: Culicidae) complex in 23 sites in Cameroon, Central Africa. Almost all...

Geographic Distribution and Breeding Site Preference of Aedes albopictus and Aedes aegypti (Diptera: Culicidae) in Cameroon, Central Africa (2005)

Frédéric Simard, Elysée Nchoutpouen, Jean Claude Toto, Didier Fontenille

Presence in Cameroon of the recently introduced Aedes (Stegomyia) albopictus (Skuse) in association with the indigenous Aedes aegypti (L.) raises public heath concerns because it might alter the risk...

Erratum (2005)

Koum, Guillaume, Yekel, Augustin, Ndifon, Bengyella, Simard, Frédéric

Summary: There have been constant changes in the biology and behavior of the vector and parasite involved in the transmission of malaria. There is limited interest in developing new technologies and...

Design and implementation of a mosquitoes database through an entomological ontology (2004)

Koum, Guillaume, Yekel, Augustin, Ndifon, Bengyella, Simard, Frédéric

There has been some constant changes in the biology and behaviour of the vector and parasite involved in the transmission of malaria. The limited interest in developing new technologies and...

Design and implementation of a mosquito database through an entomological ontology (2004)

Koum, Guillaume, Yekel, Augustin, Ndifon, Bengyella, Simard, Frédéric

Summary: There have been constant changes in the biology and behavior of the vector and parasite involved in the transmission of malaria. There is limited interest in developing new technologies and...

Design and implementation of a mosquitoes database through an entomological ontology (2004)

Koum, Guillaume, Yekel, Augustin, Ndifon, Bengyella, Simard, Frédéric

There has been some constant changes in the biology and behaviour of the vector and parasite involved in the transmission of malaria. The limited interest in developing new technologies and...

Flux géniques chez Anopheles gambiae, vecteur du paludisme : implication dans la transmission (1996)

Simard, Frédéric, Diatta, Mathurin, Lemasson, Jean-Jacques, Lehmann, T., Collins, F., Fontenille, Didier

L'étude de la génétique des populations des anophèles du complexe Anopheles gambiae s.l., principal vecteur du paludisme humain en Afrique a été entreprise au laboratoire ORSTOM de Zoologie...

Genetic differentiation of Anopheles gambiae populations from East and West Africa : comparison of microsatellite and allozyme loci (1996)

Lehmann, T., Hawley, W.A., Kamau, L., Fontenille, Didier, Simard, Frédéric, Collins, F.H.

Genetic variation of Anopheles gambiae was analysed to assess interpopulation divergence over a 6000 km distance using short tandem repeat (microsatellite) loci and allozyme loci. Differentiation of...

The analysis and simulation of a generalized hybrid ARQ system for a burst-noise channel / (1990)

Simard, Frédéric

As digital systems become widespread, the importance of error control in these systems increases. Further, since most channels cannot be realistically modelled by a simple Binary Symmetric Channel,...

Gene Flow Between Chromosomal Forms of the Malaria Vector Anopheles funestus in Cameroon, Central Africa, and Its Relevance in Malaria Fighting

Cohuet, Anna, Dia, Ibrahima, Simard, Frédéric, Raymond, Michel, Rousset, François, Antonio-Nkondjio, Christophe, ...

Knowledge of population structure in a major vector species is fundamental to an understanding of malaria epidemiology and becomes crucial in the context of genetic control strategies that are being...

Breakpoint structure reveals the unique origin of an interspecific chromosomal inversion (2La) in the Anopheles gambiae complex

Sharakhov, Igor V., White, Bradley J., Sharakhova, Maria V., Kayondo, Jonathan, Lobo, Neil F., Santolamazza, Federica, ...

Paracentric chromosomal inversions are major architects of organismal evolution and have been associated with adaptations relevant to malaria transmission in anopheline mosquitoes. The processes...

Gene Flow Between Chromosomal Forms of the Malaria Vector Anopheles funestus in Cameroon, Central Africa, and Its Relevance in Malaria Fighting

Cohuet, Anna, Dia, Ibrahima, Simard, Frédéric, Raymond, Michel, Rousset, François, Antonio-Nkondjio, Christophe, ...

Knowledge of population structure in a major vector species is fundamental to an understanding of malaria epidemiology and becomes crucial in the context of genetic control strategies that are being...

Breakpoint structure reveals the unique origin of an interspecific chromosomal inversion (2La) in the Anopheles gambiae complex

Sharakhov, Igor V., White, Bradley J., Sharakhova, Maria V., Kayondo, Jonathan, Lobo, Neil F., Santolamazza, Federica, ...

Paracentric chromosomal inversions are major architects of organismal evolution and have been associated with adaptations relevant to malaria transmission in anopheline mosquitoes. The processes...

Population genetic structure of Plasmodium falciparum in the two main African vectors, Anopheles gambiae and Anopheles funestus

Annan, Zeinab, Durand, Patrick, Ayala, Francisco J., Arnathau, Céline, Awono-Ambene, Parfait, Simard, Frédéric, ...

We investigated patterns of genetic diversity of Plasmodium falciparum associated with its two main African vectors: Anopheles gambiae and Anopheles funestus. We dissected 10,296 wild-caught...

Multiple Origins of Knockdown Resistance Mutations in the Afrotropical Mosquito Vector Anopheles gambiae

Pinto, João, Lynd, Amy, Vicente, José L., Santolamazza, Federica, Randle, Nadine P., Gentile, Gabriele, ...

How often insecticide resistance mutations arise in natural insect populations is a fundamental question for understanding the evolution of resistance and also for modeling its spread. Moreover, the...