François Canonne-Hergaux

Functional Expression of Nramp1 In Vitro in the Murine Macrophage Line RAW264.7

Govoni, Gregory, Canonne-Hergaux, François, Pfeifer, Cheryl G., Marcus, Sandra L., Mills, Scott D., Hackam, David J., ...

Mutations at the Nramp1 locus in vivo cause susceptibility to infection by unrelated intracellular microbes. Nramp1 encodes an integral membrane protein abundantly expressed in the...

Wild-type and mutant ferroportins do not form oligomers in transfected cells

Gonçalves, Ana Sofia, Muzeau, Françoise, Blaybel, Rand, Hetet, Gilles, Driss, Fathi, Delaby, Constance, ...

Ferroportin [FPN; Slc40a1 (solute carrier family 40, member 1)] is a transmembrane iron export protein expressed in macrophages and duodenal enterocytes. Heterozygous mutations in the FPN gene result...

Functional Expression of Nramp1 In Vitro in the Murine Macrophage Line RAW264.7

Govoni, Gregory, Canonne-Hergaux, François, Pfeifer, Cheryl G., Marcus, Sandra L., Mills, Scott D., Hackam, David J., ...

Mutations at the Nramp1 locus in vivo cause susceptibility to infection by unrelated intracellular microbes. Nramp1 encodes an integral membrane protein abundantly expressed in the...

Wild-type and mutant ferroportins do not form oligomers in transfected cells

Gonçalves, Ana Sofia, Muzeau, Françoise, Blaybel, Rand, Hetet, Gilles, Driss, Fathi, Delaby, Constance, ...

Ferroportin [FPN; Slc40a1 (solute carrier family 40, member 1)] is a transmembrane iron export protein expressed in macrophages and duodenal enterocytes. Heterozygous mutations in the FPN gene result...

The Iron Transport Protein NRAMP2 Is an Integral Membrane Glycoprotein That Colocalizes with Transferrin in Recycling Endosomes

Gruenheid, Samantha, Canonne-Hergaux, François, Gauthier, Susan, Hackam, David J., Grinstein, Sergio, Gros, Philippe

The natural resistance associated macrophage protein (Nramp) gene family is composed of two members in mammals, Nramp1 and Nramp2. Nramp1 is expressed primarily in macrophages and mutations at this...

Pyruvate kinase deficiency confers susceptibility to Salmonella typhimurium infection in mice

Roy, Marie-France, Riendeau, Noémie, Bédard, Christian, Hélie, Pierre, Min-Oo, Gundula, Turcotte, Karine, ...

The mouse response to acute Salmonella typhimurium infection is complex, and it is under the influence of several genes, as well as environmental factors. In a previous study, we identified two novel...