Francesco Pacifico

Role of the adaptor protein CIKS in the activation of the IKK complex (2003)

Mauro, Claudio, Vito, Pasquale, Mellone, Stefano, Pacifico, Francesco, Chariot, Alain, Formisano, Silvestro, ...

Nuclear factor kappaB (NF-kappaB) plays a pivotal role in numerous cellular processes, including stress response, inflammation, and protection from apoptosis. Therefore, the activity of NF-kappaB...

Activated platelets and leucocytes cooperatively stimulate smooth muscle cell proliferation and proto-oncogene expression via release of soluble growth factors (1999)

Cirillo, Plinio, Golino, Paolo, Ragni, Massimo, Battaglia, Carmine, Pacifico, Francesco, Formisano, Silvestro, ...

Background: Previous studies indicate that platelets and leucocytes might contribute to the development of neointimal hyperplasia following arterial injury. The present study was aimed at further...

Folding of thyroglobulin in the calnexin/calreticulin pathway and its alteration by loss of Ca2+ from the endoplasmic reticulum.

Di Jeso, Bruno, Ulianich, Luca, Pacifico, Francesco, Leonardi, Antonio, Vito, Pasquale, Consiglio, Eduardo, ...

During its initial folding in the endoplasmic reticulum (ER), newly synthesized thyroglobulin (Tg) is known to interact with calnexin and other ER molecular chaperones, but its interaction with...

Folding of thyroglobulin in the calnexin/calreticulin pathway and its alteration by loss of Ca2+ from the endoplasmic reticulum.

Di Jeso, Bruno, Ulianich, Luca, Pacifico, Francesco, Leonardi, Antonio, Vito, Pasquale, Consiglio, Eduardo, ...

During its initial folding in the endoplasmic reticulum (ER), newly synthesized thyroglobulin (Tg) is known to interact with calnexin and other ER molecular chaperones, but its interaction with...

The neutrophil gelatinase-associated lipocalin (NGAL), a NF-κB-regulated gene, is a survival factor for thyroid neoplastic cells

Iannetti, Alessio, Pacifico, Francesco, Acquaviva, Renato, Lavorgna, Alfonso, Crescenzi, Elvira, Vascotto, Carlo, ...

NF-κB is constitutively activated in primary human thyroid tumors, particularly in those of anaplastic type. The inhibition of NF-κB activity in the human anaplastic thyroid carcinoma cell line,...