Francis Galibert

Revisiting the missing protein-coding gene catalog of the domestic dog (2009)

Derrien, Thomas, Thézé, Julien, Vaysse, Amaury, André, Catherine, Ostrander, Elaine A, Galibert, Francis, ...

Abstract Background Among mammals for which there is a high sequence coverage, the whole genome assembly of the dog is unique in that it predicts a low number of protein-coding genes, ~19,000,...

Genetic diversity of canine olfactory receptors (2009)

Robin, Stéphanie, Tacher, Sandrine, Rimbault, Maud, Vaysse, Amaury, Dréano, Stéphane, André, Catherine, ...

Abstract Background Evolution has resulted in large repertoires of olfactory receptor (OR) genes, forming the largest gene families in mammalian genomes. Knowledge of the genetic diversity of...

Genetic diversity of canine olfactory receptors. (2009)

Robin, Stephanie, Tacher, Sandrine, Rimbault, Maud, Vaysse, Amaury, Dreano, Stephane, Andre, Catherine, ...

ABSTRACT: BACKGROUND: Evolution has resulted in large repertoires of olfactory receptor (OR) genes, forming the largest gene families in mammalian genomes. Knowledge of the genetic diversity of...

Genetic diversity of canine olfactory receptors. (2009)

Robin, Stephanie, Tacher, Sandrine, Rimbault, Maud, Vaysse, Amaury, Dreano, Stephane, Andre, Catherine, ...

ABSTRACT: BACKGROUND: Evolution has resulted in large repertoires of olfactory receptor (OR) genes, forming the largest gene families in mammalian genomes. Knowledge of the genetic diversity of...

Revisiting the missing protein-coding gene catalog of the domestic dog. (2009)

Derrien, Thomas, Thézé, Julien, Vaysse, Amaury, André, Catherine, Ostrander, Elaine, Galibert, Francis, ...

BACKGROUND: Among mammals for which there is a high sequence coverage, the whole genome assembly of the dog is unique in that it predicts a low number of protein-coding genes, ~19,000, compared to...

Revisiting the missing protein-coding gene catalog of the domestic dog. (2009)

Derrien, Thomas, Thézé, Julien, Vaysse, Amaury, André, Catherine, Ostrander, Elaine, Galibert, Francis, ...

BACKGROUND: Among mammals for which there is a high sequence coverage, the whole genome assembly of the dog is unique in that it predicts a low number of protein-coding genes, ~19,000, compared to...

Revisiting the missing protein-coding gene catalog of the domestic dog. (2009)

Derrien, Thomas, Thézé, Julien, Vaysse, Amaury, André, Catherine, Ostrander, Elaine, Galibert, Francis, ...

BACKGROUND: Among mammals for which there is a high sequence coverage, the whole genome assembly of the dog is unique in that it predicts a low number of protein-coding genes, ~19,000, compared to...

Genetic diversity of canine olfactory receptors. (2009)

Robin, Stephanie, Tacher, Sandrine, Rimbault, Maud, Vaysse, Amaury, Dreano, Stephane, Andre, Catherine, ...

ABSTRACT: BACKGROUND: Evolution has resulted in large repertoires of olfactory receptor (OR) genes, forming the largest gene families in mammalian genomes. Knowledge of the genetic diversity of...

Ancestral T-Box Mutation Is Present in Many, but Not All, Short-Tailed Dog Breeds (2009)

Hytönen, Marjo K., Grall, Anaïs, Hédan, Benoît, Dréano, Stéphane, Seguin, Samuel J., Delattre, Delphine, ...

Dogs differ greatly in their morphological characteristics including various tail phenotypes. Congenitally short-tailed dogs are present in many breeds; however, the causative mutation located in the...

Chromosomal Mapping of Canine-Derived BAC Clones to the Red Fox and American Mink Genomes (2009)

Kukekova, Anna V., Vorobieva, Nadegda V., Beklemisheva, Violetta R., Johnson, Jennifer L., Temnykh, Svetlana V., Yudkin, Dmitry V., ...

High-quality sequencing of the dog (Canis lupus familiaris) genome has enabled enormous progress in genetic mapping of canine phenotypic variation. The red fox (Vulpes vulpes), another canid species,...

Epidemiology, Pathology, and Genetics of Histiocytic Sarcoma in the Bernese Mountain Dog Breed (2009)

Abadie, Jérôme, Hédan, Benoit, Cadieu, Edouard, De Brito, Clotilde, Devauchelle, Patrick, Bourgain, Catherine, ...

Histiocytic sarcoma (HS) refers to a highly aggressive and frequently disseminated neoplastic disease belonging to the class of canine histiocytic proliferative disorders. Disseminated HS (previously...

comparative genome (2008)

Thomas Derrien, Catherine André, Francis Galibert, Christophe Hitte, Alfonso Valencia

AutoGRAPH: an interactive web server for automating and visualizing

Progressive Retinal Atrophy in the Border Collie: A new XLPRA (2008)

Vilboux, Thierry, Chaudieu, Gilles, Jeannin, Patricia, Delattre, Delphine, Hedan, Benoit, Bourgain, Catherine, ...

Abstract Background Several forms of progressive retinal atrophy (PRA) segregate in more than 100 breeds of dog with each PRA segregating in one or a few breeds. This breed specificity may be...

Survey sequencing and radiation hybrid mapping to construct comparative maps. (2008)

Hitte, Christophe, Kirkness, Ewen, Ostrander, Elaine A, Galibert, Francis

Radiation hybrid (RH) mapping has become one of the most well-established techniques for economically and efficiently navigating genomes of interest. The success of the technique relies on random...

Survey sequencing and radiation hybrid mapping to construct comparative maps. (2008)

Hitte, Christophe, Kirkness, Ewen, Ostrander, Elaine A, Galibert, Francis

Radiation hybrid (RH) mapping has become one of the most well-established techniques for economically and efficiently navigating genomes of interest. The success of the technique relies on random...

Functional Analysis of a Subset of Canine Olfactory Receptor Genes (2007)

Benbernou, Naima, Tacher, Sandrine, Robin, Stéphanie, Rakotomanga, Michaelle, Senger, Fabrice, Galibert, Francis

In this paper, we explored the level complexity of the combinatorial olfactory code that allows mammals with a repertoire of about thousand putatively active olfactory receptors encoded in their...

Analysis of the Unassembled Part of the Dog Genome Sequence: Chromosomal Localization of 115 Genes Inferred from Multispecies Comparative Genomics (2007)

Derrien, Thomas, André, Catherine, Galibert, Francis, Hitte, Christophe

The identification of dog genes and their accurate localization to chromosomes remain a major challenge in the postgenomics era. The 132 annotated canine genes with human orthologs remaining in the...

An Extended Microsatellite Set for Linkage Mapping in the Domestic Dog (2007)

Sargan, David R., Aguirre-Hernandez, Jesus, Galibert, Francis, Ostrander, Elaine A.

The extremes of phenotype displayed by the domestic dog, as well as the largest number of naturally occurring inherited diseases in any mammalian species except man (>450), have generated a large...

A gene-based radiation hybrid map of the gilthead sea bream Sparus auratarefines and exploits conserved synteny with Tetraodon nigroviridis (2007)

Sarropoulou, Elena, Franch, Rafaella, Louro, Bruno, Power, Deborah M, Bargelloni, Luca, Magoulas, Antonios, ...

Abstract Background Comparative teleost studies are of great interest since they are important in aquaculture and in evolutionary issues. Comparing genomes of fully sequenced model fish species with...

A comparative genome approach to marker ordering (2007)

Thomas Faraut, Simon De Givry, Patrick Chabrier, Thomas Derrien, Francis Galibert, Christophe Hitte, ...

∗ Both authors contributed equally to this work. Abstract: The increased number of genomes being sequenced offers new opportunities for the mapping of closely related organisms. We propose an...

A gene-based radiation hybrid map of the gilthead sea bream Sparus aurata refines and exploits conserved synteny with Tetraodon nigroviridis (2007)

Sarropoulou, Elena, Franch, Rafaella, Louro, Bruno, Power, Deborah M, Bargelloni, Luca, Magoulas, Antonios, ...

Background Comparative teleost studies are of great interest since they are important in aquaculture and in evolutionary issues. Comparing genomes of fully sequenced model fish species with those of...

AutoGRAPH: an interactive web server for automating and visualizing comparative genome maps (2007)

Derrien, Thomas, André, Catherine, Galibert, Francis, Hitte, Christophe

AutoGRAPH is an interactive web server for automatic multi-species comparative genomics analyses based on personal datasets or pre-inserted public datasets. This program automatically identifies...

Coat colour in dogs: identification of the Merlelocus in the Australian shepherd breed (2006)

Hédan, Benoit, Corre, Sébastien, Hitte, Christophe, Dréano, Stéphane, Vilboux, Thierry, Derrien, Thomas, ...

Abstract Background Coat colours in canines have many natural phenotypic variants. Some of the genes and alleles involved also cause genetic developmental defects, which are also observed in humans...

BIOINFORMATICS APPLICATIONS NOTE (2006)

Genome Analysis, Thomas Derrien, Catherine André, Francis Galibert, Christophe Hitte

Vol. 23 no. 4 2007, pages 498–499 doi:10.1093/bioinformatics/btl618 AutoGRAPH: an interactive web server for automating and visualizing comparative genome maps

The dog and rat olfactory receptor repertoires (2005)

Quignon, Pascale, Giraud, Mathieu, Rimbault, Maud, Lavigne, Patricia, Tacher, Sandrine, Morin, Emmanuelle, ...

Abstract Background Dogs and rats have a highly developed capability to detect and identify odorant molecules, even at minute concentrations. Previous analyses have shown that the olfactory receptors...

Olfactory Receptor Sequence Polymorphism Within and Between Breeds of Dogs (2005)

Tacher, Sandrine, Quignon, Pascale, Rimbault, Maud, Dreano, Stephane, Andre, Catherine, Galibert, Francis

Olfactory receptors, to which odorant molecules specifically bind, are encoded by the largest gene family yet identified in the mammalian genome. We investigated additional polymorphism due to the...

Construction of a 2-Mb resolution BAC microarray for CGH analysis of canine tumors (2005)

Thomas, Rachael, Scott, Allyson, Langford, Cordelia F., Fosmire, Susan P., Jubala, Cristan M., Lorentzen, Travis D., ...

Recognition of the domestic dog as a model for the comparative study of human genetic traits has led to major advances in canine genomics. The pathophysiological similarities shared between many...

Olfactory Receptor Sequence Polymorphism Within and Between Breeds of Dogs (2005)

Tacher, Sandrine, Quignon, Pascale, Rimbault, Maud, Dreano, Stephane, Andre, Catherine, Galibert, Francis

Olfactory receptors, to which odorant molecules specifically bind, are encoded by the largest gene family yet identified in the mammalian genome. We investigated additional polymorphism due to the...

An integrated 4249 marker FISH/RH map of the canine genome (2004)

Breen, Matthew, Hitte, Christophe, Lorentzen, Travis D, Thomas, Rachael, Cadieu, Edouard, Sabacan, Leah, ...

Abstract Background The 156 breeds of dog recognized by the American Kennel Club offer a unique opportunity to map genes important in genetic variation. Each breed features a defining constellation...

CRH_Server: an online comparative and radiation hybrid mapping server for the canine genome (2004)

Hitte, Christophe, Derrien, Thomas, André, Catherine, Ostrander, Elaine A., Galibert, Francis

Summary: CRH_Server is an on line Comparative and Radiation Hybrid mapping Server dedicated to canine genomics. CRH_Server allows users to compute their own RH data using the current canine RH map,...

CRH_server: an online comparative and radiation hybrid mapping server for the canine genome (2004)

Hitte, Christophe, Derrien, Thomas, André, Catherine, Ostrander, Elaine A., Galibert, Francis

Summary: CRH_Server is an on line Comparative and Radiation Hybrid mapping Server dedicated to canine genomics. CRH_Server allows users to compute their own RH data using the current canine RH map,...

CRH_server: an online comparative and radiation hybrid mapping server for the canine genome (2004)

Hitte, Christophe, Derrien, Thomas, André, Catherine, Ostrander, Elaine A., Galibert, Francis

Summary: CRH_Server is an on line Comparative and Radiation Hybrid mapping Server dedicated to canine genomics. CRH_Server allows users to compute their own RH data using the current canine RH map,...

Comparison of the canine and human olfactory receptor gene repertoires (2003)

Quignon, Pascale, Kirkness, Ewen, Cadieu, Edouard, Touleimat, Nizar, Guyon, Richard, Renier, Corinne, ...

Abstract Background Olfactory receptors (ORs), the first dedicated molecules with which odorants physically interact to arouse an olfactory sensation, constitute the largest gene family in...

A Mutation in the Canine BHD Gene is Associated with Hereditary Multifocal Renal Cystadenocarcinoma and Nodular Dermatofibrosis in the German Shepherd Dog (2003)

Lingaas, Frode, Comstock, Kenine E., Kirkness, Ewen F., Sørensen, Anita, Aarskaug, Tone, Hitte, Christophe, ...

Hereditary multifocal renal cystadenocarcinoma and nodular dermatofibrosis (RCND) is a naturally occurring canine kidney cancer syndrome that was originally described in German Shepherd dogs. The...

A mutation in the canine BHD gene is associated with hereditary multifocal renal cystadenocarcinoma and nodular dermatofibrosis in the German Shepherd dog (2003)

Lingaas, Frode, Comstock, Kenine E., Kirkness, Ewen F., Sørensen, Anita, Aarskaug, Tone, Hitte, Christophe, ...

Hereditary multifocal renal cystadenocarcinoma and nodular dermatofibrosis (RCND) is a naturally occurring canine kidney cancer syndrome that was originally described in German Shepherd dogs. The...

A Mutation in the Canine BHD Gene is Associated with Hereditary Multifocal Renal Cystadenocarcinoma and Nodular Dermatofibrosis in the German Shepherd Dog (2003)

Lingaas, Frode, Comstock, Kenine E., Kirkness, Ewen F., Sørensen, Anita, Aarskaug, Tone, Hitte, Christophe, ...

Hereditary multifocal renal cystadenocarcinoma and nodular dermatofibrosis (RCND) is a naturally occurring canine kidney cancer syndrome that was originally described in German Shepherd dogs. The...

Mapping and identification of essential gene functions on the X chromosome of Drosophila (2002)

Peter, Annette, Schoettler, Petra, Werner, Meike, Beinert, Nicole, Dowe, Gordon, Burkert, Peter, ...

The Drosophila melanogaster genome consists of four chromosomes that contain 165 Mb of DNA, 120 Mb of which are euchromatic. The two Drosophila Genome Projects, in collaboration with Celera Genomics...

From First Base: the sequence of the Tip of the X Chromosome of Drosophila melanogaster, a comparison of two sequencing strategies (2001)

Benos, Panayiotis V., Gatt, Melanie K., Murphy, Lee, Harris, David, Barrell, Bart, Ferraz, Concepcion, ...

We present the sequence of a contiguous 2.63 Mb of DNA extending from the tip of the X chromosome of Drosophila melanogaster. Within this sequence, we predict 277 protein coding genes, of which 94...

Ribosomal protein gene cluster analysis in eubacterium genomics: homology between Sinorhizobium meliloti strain 1021 and Bacillus subtilis (2001)

Barloy-Hubler, Frédérique, Lelaure, Valérie, Galibert, Francis

The first whole genome sequence of a symbiotic soil bacterium, Sinorhizobium meliloti (formely named Rhizobium meliloti) strain 1021, is due in 2001. As an active participant in the European and...

Organization and expres of the E4 region of adenovirus 2 (1984)

Rigolet, Muriel, Galibert, Francis

The E4 region of Adenovirus 2 is a leftward transcribed part of the viral genome. Its nucleotide sequence has already been analysed. From this sequence several open reading frames were defined, which...

Base specificity of mismatch repair in Streptococcus pneumoniae (1981)

Claverys, Jean-Pierre, Méjean, Vincent, Gasc, Anne-Marie, Galibert, Francis, Sicard, Armand-Michel

DNA sequence analysis was undertaken to investigate the structural basis of mutations showing different integration efficiencies in Streptococcus pneumoniae. Wild type, mutant and revertant sequences...

Nucleotide sequence of the EcoRI E fragment of adenovirus 2 genome (1981)

Hérissé, Jacques, Galibert, Francis

The entire nucleotide sequence of the Ad.2 EcoRI E fragment has been determined using the Maxam and Gilbert method. This sequence of 2222 bp, which maps between coordinate 83.4 and 89.7 contains...

Nucleotide sequence of the EcoR1 D fragment of adenovirus 2 genome (1980)

Hérissé, Jacques, Courtois, Geneviéve, Galibert, Francis

The entire nucleotide sequence of the Ad. 2 EcoRI D fragment has been determined using the Maxam and Gilbert method. This sequence of 2678 bp contains informations relative to late mRNAs ending at...

Localization on the viral genome and nucleotide sequence of the gene coding for the two major polypeptides of the Hepatitis B surface antigen (HBs Ag) (1979)

Charnay, Patrick, Mandart, Elisabeth, Hampe, Annie, Fitoussi, Françoise, Tiollais, Pierre, Galibert, Francis

The structural gene coding for both polypeptides I and II which are the two major polypeptides of the Hepatitis B surface antigen, is found to be localized on the viral genome. This gene, referred to...

Bacteriophage lambda and plasmid vectors, allowing fusion of cloned genes in each of the three translational phases (1978)

Charnay, Patrick, Perricaudet, Michel, Galibert, Francis, Tiollais, Pierre

We have constructed vectors from bacteriophage lambda and from plasmid pBR322 having a single EcoRI restriction site which is immediatly downstream from the lac UV5 promotor. Each vector allows the...

Nucleotide sequence neighbouring a late modified guanylic residue within the 28S ribosomal RNA of several eukaryotic cells (1977)

Eladari, Marthe-Elisabeth, Hampe, Annie, Galibert, Francis

The nucleotide sequence of a particular T1 oligonucleotide found in 4 IS and 28S RNAs of several cellular cell lines (human, mouse, rat and chicken fibroblast) but absent in 45S ribosomal RNA has...

Sequence determination of the 3' terminal T1 oligonucleotide of 18S ribosomal RNA (1976)

Eladari, Marthe-Elisabeth, Galibert, Francis

We have reexamined the primary structure of the 3′ terminal oligonucleotide of 18S RNA from chicken fibroblasts and have shown, contrary to previously published results that this extremity...

A high-density physical map of Sinorhizobium meliloti 1021 chromosome derived from bacterial artificial chromosome library

Capela, Delphine, Barloy-Hubler, Frédérique, Gatius, Marie-Thérèse, Gouzy, Jérôme, Galibert, Francis

As part of the European Sinorhizobium meliloti (strain 1021) chromosome sequencing project, four genomic bacterial artificial chromosome (BAC) libraries have been constructed, one of which was mainly...

Analysis of the chromosome sequence of the legume symbiont Sinorhizobium meliloti strain 1021

Capela, Delphine, Barloy-Hubler, Frédérique, Gouzy, Jérôme, Bothe, Gordana, Ampe, Frédéric, Batut, Jacques, ...

Sinorhizobium meliloti is an α-proteobacterium that forms agronomically important N2-fixing root nodules in legumes. We report here the complete sequence of the largest constituent of its genome, a...

Nucleotide sequence and predicted functions of the entire Sinorhizobium meliloti pSymA megaplasmid

Barnett, Melanie J., Fisher, Robert F., Jones, Ted, Komp, Caridad, Abola, A. Pia, Barloy-Hubler, Frédérique, ...

The symbiotic nitrogen-fixing soil bacterium Sinorhizobium meliloti contains three replicons: pSymA, pSymB, and the chromosome. We report here the complete 1,354,226-nt sequence of pSymA. In addition...

Ribosomal protein gene cluster analysis in eubacterium genomics: homology between Sinorhizobium meliloti strain 1021 and Bacillus subtilis

Barloy-Hubler, Frédérique, Lelaure, Valérie, Galibert, Francis

The first whole genome sequence of a symbiotic soil bacterium, Sinorhizobium meliloti (formely named Rhizobium meliloti) strain 1021, is due in 2001. As an active participant in the European and...

High-Resolution Physical Map of the Sinorhizobium meliloti 1021 pSyma Megaplasmid

Barloy-Hubler, Frederique, Capela, Delphine, Barnett, Melanie J., Kalman, Sue, Federspiel, Nancy A., Long, Sharon R., ...

To facilitate sequencing of the Sinorhizobium meliloti 1021 pSyma megaplasmid, a high-resolution map was constructed by ordering 113 overlapping bacterial artificial chromosome clones with 192...

A 1-Mb resolution radiation hybrid map of the canine genome

Guyon, Richard, Lorentzen, Travis D., Hitte, Christophe, Kim, Lisa, Cadieu, Edouard, Parker, Heidi G., ...

The purebred dog population consists of >300 partially inbred genetic isolates or breeds. Restriction of gene flow between breeds, together with strong selection for traits, has led to the...

Mutant Feline Sarcoma Proviruses Containing the Viral Oncogene (v-fes) and Either Feline or Murine Control Elements

Even, Jos, Anderson, Soni J., Hampe, Annie, Galibert, Francis, Lowy, Douglas, Khoury, George, ...

The sequences required for transformation by the Gardner-Arnstein (GA) strain of feline sarcoma virus (GA-FeSV) were defined by site-directed, in vitro mutagenesis of molecularly cloned proviral DNA....

From First Base: The Sequence of the Tip of the X Chromosome of Drosophila melanogaster, a Comparison of Two Sequencing Strategies

Benos, Panayiotis V., Gatt, Melanie K., Murphy, Lee, Harris, David, Barrell, Bart, Ferraz, Concepcion, ...

We present the sequence of a contiguous 2.63 Mb of DNA extending from the tip of the X chromosome of Drosophila melanogaster. Within this sequence, we predict 277 protein coding genes, of which 94...

Chromosome-Specific Single-Locus FISH Probes Allow Anchorage of an 1800-Marker Integrated Radiation-Hybrid/Linkage Map of the Domestic Dog Genome to All Chromosomes

Breen, Matthew, Jouquand, Sophie, Renier, Corinne, Mellersh, Cathryn S., Hitte, Christophe, Holmes, Nigel G., ...

We present here the first fully integrated, comprehensive map of the canine genome, incorporating detailed cytogenetic, radiation hybrid (RH), and meiotic information. We have mapped a collection of...

Comparison of the canine and human olfactory receptor gene repertoires

Quignon, Pascale, Kirkness, Ewen, Cadieu, Edouard, Touleimat, Nizar, Guyon, Richard, Renier, Corinne, ...

In this study, 817 novel canine olfactory receptor (OR) sequences were identified, and 640 have been characterized. Of the 661 characterized OR sequences, representing half of the canine repertoire,...

Evidence for the Existence of Several Molecular Species in the “45S Fraction” of Mammalian Ribosomal Precursor RNA

Tiollais, Pierre, Galibert, Francis, Boiron, Michel

Analysis of RNA (after 5 or 60 min of labeling with [3H]uridine) from L5178Y cells by electrophoresis in 1.7% polyacrylamide gels demonstrates that the ribosomal RNA “45S fraction“ is not...

Mapping and identification of essential gene functions on the X chromosome of Drosophila

Peter, Annette, Schöttler, Petra, Werner, Meike, Beinert, Nicole, Dowe, Gordon, Burkert, Peter, ...

The Drosophila melanogaster genome consists of four chromosomes that contain 165 Mb of DNA, 120 Mb of which are euchromatic. The two Drosophila Genome Projects, in collaboration with Celera Genomics...

The dog and rat olfactory receptor repertoires

Quignon, Pascale, Giraud, Mathieu, Rimbault, Maud, Lavigne, Patricia, Tacher, Sandrine, Morin, Emmanuelle, ...

An almost complete list of odorant receptor genes in the dog (1,094 genes) and the rat (1,493 genes) is described. A comparison of odorant receptor repertoires in rat, dog, mouse and human is also...

Construction of a 2-Mb resolution BAC microarray for CGH analysis of canine tumors

Thomas, Rachael, Scott, Allyson, Langford, Cordelia F., Fosmire, Susan P., Jubala, Cristan M., Lorentzen, Travis D., ...

Recognition of the domestic dog as a model for the comparative study of human genetic traits has led to major advances in canine genomics. The pathophysiological similarities shared between many...

Pol32, a subunit of Saccharomyces cerevisiae DNA polymerase delta, suppresses genomic deletions and is involved in the mutagenic bypass pathway.

Huang, Meng-Er, Rio, Anne-Gaëlle, Galibert, Marie-Dominique, Galibert, Francis

The Pol32 subunit of S. cerevisiae DNA polymerase (Pol) delta plays an important role in replication and mutagenesis. Here, by measuring the CAN1 forward mutation rate, we found that either POL32 or...

Eukaryotic control on bacterial cell cycle and differentiation in the Rhizobium–legume symbiosis

Mergaert, Peter, Uchiumi, Toshiki, Alunni, Benoît, Evanno, Gwénaëlle, Cheron, Angélique, Catrice, Olivier, ...

Symbiosis between legumes and Rhizobium bacteria leads to the formation of root nodules where bacteria in the infected plant cells are converted into nitrogen-fixing bacteroids. Nodules with a...

A high-density physical map of Sinorhizobium meliloti 1021 chromosome derived from bacterial artificial chromosome library

Capela, Delphine, Barloy-Hubler, Frédérique, Gatius, Marie-Thérèse, Gouzy, Jérôme, Galibert, Francis

As part of the European Sinorhizobium meliloti (strain 1021) chromosome sequencing project, four genomic bacterial artificial chromosome (BAC) libraries have been constructed, one of which was mainly...

Analysis of the chromosome sequence of the legume symbiont Sinorhizobium meliloti strain 1021

Capela, Delphine, Barloy-Hubler, Frédérique, Gouzy, Jérôme, Bothe, Gordana, Ampe, Frédéric, Batut, Jacques, ...

Sinorhizobium meliloti is an α-proteobacterium that forms agronomically important N2-fixing root nodules in legumes. We report here the complete sequence of the largest constituent of its genome, a...

Nucleotide sequence and predicted functions of the entire Sinorhizobium meliloti pSymA megaplasmid

Barnett, Melanie J., Fisher, Robert F., Jones, Ted, Komp, Caridad, Abola, A. Pia, Barloy-Hubler, Frédérique, ...

The symbiotic nitrogen-fixing soil bacterium Sinorhizobium meliloti contains three replicons: pSymA, pSymB, and the chromosome. We report here the complete 1,354,226-nt sequence of pSymA. In addition...

Ribosomal protein gene cluster analysis in eubacterium genomics: homology between Sinorhizobium meliloti strain 1021 and Bacillus subtilis

Barloy-Hubler, Frédérique, Lelaure, Valérie, Galibert, Francis

The first whole genome sequence of a symbiotic soil bacterium, Sinorhizobium meliloti (formely named Rhizobium meliloti) strain 1021, is due in 2001. As an active participant in the European and...

High-Resolution Physical Map of the Sinorhizobium meliloti 1021 pSyma Megaplasmid

Barloy-Hubler, Frederique, Capela, Delphine, Barnett, Melanie J., Kalman, Sue, Federspiel, Nancy A., Long, Sharon R., ...

To facilitate sequencing of the Sinorhizobium meliloti 1021 pSyma megaplasmid, a high-resolution map was constructed by ordering 113 overlapping bacterial artificial chromosome clones with 192...

A 1-Mb resolution radiation hybrid map of the canine genome

Guyon, Richard, Lorentzen, Travis D., Hitte, Christophe, Kim, Lisa, Cadieu, Edouard, Parker, Heidi G., ...

The purebred dog population consists of >300 partially inbred genetic isolates or breeds. Restriction of gene flow between breeds, together with strong selection for traits, has led to the...

Mutant Feline Sarcoma Proviruses Containing the Viral Oncogene (v-fes) and Either Feline or Murine Control Elements

Even, Jos, Anderson, Soni J., Hampe, Annie, Galibert, Francis, Lowy, Douglas, Khoury, George, ...

The sequences required for transformation by the Gardner-Arnstein (GA) strain of feline sarcoma virus (GA-FeSV) were defined by site-directed, in vitro mutagenesis of molecularly cloned proviral DNA....

From First Base: The Sequence of the Tip of the X Chromosome of Drosophila melanogaster, a Comparison of Two Sequencing Strategies

Benos, Panayiotis V., Gatt, Melanie K., Murphy, Lee, Harris, David, Barrell, Bart, Ferraz, Concepcion, ...

We present the sequence of a contiguous 2.63 Mb of DNA extending from the tip of the X chromosome of Drosophila melanogaster. Within this sequence, we predict 277 protein coding genes, of which 94...

Chromosome-Specific Single-Locus FISH Probes Allow Anchorage of an 1800-Marker Integrated Radiation-Hybrid/Linkage Map of the Domestic Dog Genome to All Chromosomes

Breen, Matthew, Jouquand, Sophie, Renier, Corinne, Mellersh, Cathryn S., Hitte, Christophe, Holmes, Nigel G., ...

We present here the first fully integrated, comprehensive map of the canine genome, incorporating detailed cytogenetic, radiation hybrid (RH), and meiotic information. We have mapped a collection of...

Comparison of the canine and human olfactory receptor gene repertoires

Quignon, Pascale, Kirkness, Ewen, Cadieu, Edouard, Touleimat, Nizar, Guyon, Richard, Renier, Corinne, ...

In this study, 817 novel canine olfactory receptor (OR) sequences were identified, and 640 have been characterized. Of the 661 characterized OR sequences, representing half of the canine repertoire,...

Evidence for the Existence of Several Molecular Species in the “45S Fraction” of Mammalian Ribosomal Precursor RNA

Tiollais, Pierre, Galibert, Francis, Boiron, Michel

Analysis of RNA (after 5 or 60 min of labeling with [3H]uridine) from L5178Y cells by electrophoresis in 1.7% polyacrylamide gels demonstrates that the ribosomal RNA “45S fraction“ is not...

Mapping and identification of essential gene functions on the X chromosome of Drosophila

Peter, Annette, Schöttler, Petra, Werner, Meike, Beinert, Nicole, Dowe, Gordon, Burkert, Peter, ...

The Drosophila melanogaster genome consists of four chromosomes that contain 165 Mb of DNA, 120 Mb of which are euchromatic. The two Drosophila Genome Projects, in collaboration with Celera Genomics...

The dog and rat olfactory receptor repertoires

Quignon, Pascale, Giraud, Mathieu, Rimbault, Maud, Lavigne, Patricia, Tacher, Sandrine, Morin, Emmanuelle, ...

An almost complete list of odorant receptor genes in the dog (1,094 genes) and the rat (1,493 genes) is described. A comparison of odorant receptor repertoires in rat, dog, mouse and human is also...

Construction of a 2-Mb resolution BAC microarray for CGH analysis of canine tumors

Thomas, Rachael, Scott, Allyson, Langford, Cordelia F., Fosmire, Susan P., Jubala, Cristan M., Lorentzen, Travis D., ...

Recognition of the domestic dog as a model for the comparative study of human genetic traits has led to major advances in canine genomics. The pathophysiological similarities shared between many...

Eukaryotic control on bacterial cell cycle and differentiation in the Rhizobium–legume symbiosis

Mergaert, Peter, Uchiumi, Toshiki, Alunni, Benoît, Evanno, Gwénaëlle, Cheron, Angélique, Catrice, Olivier, ...

Symbiosis between legumes and Rhizobium bacteria leads to the formation of root nodules where bacteria in the infected plant cells are converted into nitrogen-fixing bacteroids. Nodules with a...

Pol32, a subunit of Saccharomyces cerevisiae DNA polymerase delta, suppresses genomic deletions and is involved in the mutagenic bypass pathway.

Huang, Meng-Er, Rio, Anne-Gaëlle, Galibert, Marie-Dominique, Galibert, Francis

The Pol32 subunit of S. cerevisiae DNA polymerase (Pol) delta plays an important role in replication and mutagenesis. Here, by measuring the CAN1 forward mutation rate, we found that either POL32 or...