Kapeller, Johannes, Houghton, Lesley A., Mönnikes, Hubert, Walstab, Jutta, Möller, Dorothee, Bönisch, Heinz, ...
Diarrhea predominant irritable bowel syndrome (IBS-D) is a complex disorder related to dysfunctions in the serotonergic system. As cis-regulatory variants can play a role in the etiology of complex...
Proinflammatory cytokines cause FAT10 upregulation in cancers of liver and colon (2008)
Lukasiak, Sebastian, Schiller, Claudia, Oehlschläger, Peter, Schmidtke, Gunter, Krause, Petra, Legler, Daniel F., ...
Renner, Marcus, Bergmann, Gaby, Krebs, Inge, End, Caroline, Lyer, Stefan, Hilberg, Frank, ...
BACKGROUND & AIMS: Impaired mucosal defense plays an important role in the pathogenesis of Crohn's disease (CD), one of the main subtypes of inflammatory bowel disease (IBD). Deleted in malignant...
Jayakumar, Prerana, Berger, Irina, Autschbach, Frank, Weinstein, Mark, Funke, Benjamin, Verdin, Eric, ...
Infection of macrophages has been implicated as a critical event in the transmission and persistence of human immunodeficiency virus type 1 (HIV-1). Here, we explore whether primary X4 HIV-1 isolates...
Kienle, Peter, Koch, Moritz, Autschbach, Frank, Benner, Axel, Treiber, Martina, Wannenmacher, Michael, ...
Blood and bone marrow of 142 patients with or without preoperative chemoradiation for rectal cancer were tested for disseminated tumor cells. Preoperative chemoradiation was associated with a...
Jayakumar, Prerana, Berger, Irina, Autschbach, Frank, Weinstein, Mark, Funke, Benjamin, Verdin, Eric, ...
Infection of macrophages has been implicated as a critical event in the transmission and persistence of human immunodeficiency virus type 1 (HIV-1). Here, we explore whether primary X4 HIV-1 isolates...
Kienle, Peter, Koch, Moritz, Autschbach, Frank, Benner, Axel, Treiber, Martina, Wannenmacher, Michael, ...
Blood and bone marrow of 142 patients with or without preoperative chemoradiation for rectal cancer were tested for disseminated tumor cells. Preoperative chemoradiation was associated with a...
Heye, Tobias, Kuntz, Christian, Düx, Marcus, Encke, Jens, Palmowski, Moritz, Autschbach, Frank, ...
Our aim was to conduct a prospective study to evaluate staging accuracy of a new coil concept for endoluminal magnetic resonance imaging (MRI) on ex vivo gastric carcinomas. Twenty-eight consecutive...
Posttranslationally Modified Proteins as Mediators of Sustained Intestinal Inflammation
Andrassy, Martin, Igwe, John, Autschbach, Frank, Volz, Christian, Remppis, Andrew, Neurath, Markus F., ...
Oxidative and carbonyl stress leads to generation of Nε-carboxymethyllysine-modified proteins (CML-mps), which are known to bind the receptor for advanced glycation end products (RAGE) and induce...
In Situ Expression of Interleukin-10 in Noninflamed Human Gut and in Inflammatory Bowel Disease
Autschbach, Frank, Braunstein, Jutta, Helmke, Burkhard, Zuna, Ivan, Schürmann, Guido, Niemir, Zofia I., ...
A dysregulated secretion of contra-inflammatory cytokines such as interleukin-10 (IL-10) could play a role in the pathogenesis of inflammatory bowel disease (IBD). We have investigated the expression...
Marie-Cardine, Anne, Kirchgessner, Henning, Bruyns, Eddy, Shevchenko, Andrej, Mann, Matthias, Autschbach, Frank, ...
T lymphocytes express several low molecular weight transmembrane adaptor proteins that recruit src homology (SH)2 domain–containing intracellular molecules to the cell membrane via tyrosine-based...
Bruyns, Eddy, Marie-Cardine, Anne, Kirchgessner, Henning, Sagolla, Karin, Shevchenko, Andrej, Mann, Matthias, ...
The molecular mechanisms regulating recruitment of intracellular signaling proteins like growth factor receptor–bound protein 2 (Grb2), phospholipase Cγ1, or phosphatidylinositol 3-kinase...