Voth, Harald, Oberthuer, André, Simon, Thorsten, Kahlert, Yvonne, Berthold, Frank, Fischer, Matthias
Abstract Background HAND2 , a key regulator for the development of the sympathetic nervous system, is located on chromosome 4q33 in a head-to-head orientation with DEIN , a recently identified novel...
Rutkowski, Stefan, Gerber, Nicolas Ulrich, Von Hoff, Katja, Gnekow, Astrid, Bode, Udo, Graf, Norbert, ...
To investigate the utility of postoperative chemotherapy in delaying radiotherapy and to identify prognostic factors in early childhood medulloblastoma, we studied children younger than 3 years of...
André Oberthuer, Barbara Hero, Rüdiger Spitz, Frank Berthold, Matthias Fischer
Purpose: The tumor-associated antigen PRAME, a potential candidate for immunotherapeutic targeting, is frequently expressed in a variety of cancers. However, no information about its presence in...
Oberthuer, André, Berthold, Frank, Warnat, Patrick, Hero, Barbara, Kahlert, Yvonne, Spitz, Rüdiger, ...
PURPOSE: To develop a gene expression–based classifier for neuroblastoma patients that reliably predicts courses of the disease. PATIENTS AND METHODS: Two hundred fifty-one neuroblastoma specimens...
Chen, Qing-Rong, Bilke, Sven, Wei, Jun S, Whiteford, Craig C, Cenacchi, Nicola, Krasnoselsky, Alexei L, ...
Abstract Background Recurrent non-random genomic alterations are the hallmarks of cancer and the characterization of these imbalances is critical to our understanding of tumorigenesis and cancer...
Retention of imprinting of the human apoptosis-related gene TSSC3 in human brain tumors (2000)
Müller, Sabine, Van Den Boom, Dirk, Zirkel, Dorothea, Köster, Hubert, Berthold, Frank, Schwab, Manfred, ...
Genomic imprinting is the result of a gamete-specific modification leading to parental origin-specific gene expression in somatic cells of the offspring. Several embryonal tumors show loss of...
Strohscheer, I., Kleinert, R., Westphal, C., Schüller, J., Werner, K., Anders, O., ...
Peer Reviewed
Berlin, Akad. für Ärztl. Fortbildung d. DDR, Diss. A, 1986 (Nicht f.d. Austausch).
Neuroblastom: neue Wege in Diagnostik und Therapie mittels monoklonaler Antikörper. (1985)
Giessen, Univ., Habil.-Schr., 1985.
Chen, Qing-Rong, Bilke, Sven, Wei, Jun S, Whiteford, Craig C, Cenacchi, Nicola, Krasnoselsky, Alexei L, ...
Khan, Javed, Wei, Jun S., Ringnér, Markus, Saal, Lao H., Ladanyi, Marc, Westermann, Frank, ...
The purpose of this study was to develop a method of classifying cancers to specific diagnostic categories based on their gene expression signatures using artificial neural networks (ANNs). We...
Wei, Jun S., Greer, Braden T., Westermann, Frank, Steinberg, Seth M., Son, Chang-Gue, Chen, Qing-Rong, ...
Currently, patients with neuroblastoma are classified into risk groups (e.g., according to the Children’s Oncology Group risk-stratification) to guide physicians in the choice of the most...
Chen, Qing-Rong, Bilke, Sven, Wei, Jun S, Whiteford, Craig C, Cenacchi, Nicola, Krasnoselsky, Alexei L, ...
Krams, Matthias, Hero, Barbara, Berthold, Frank, Parwaresch, Reza, Harms, Dieter, Rudolph, Pierre
Telomerase activity (TA) is the most recently recognized prognostic factor in neuroblastoma, and its outstanding predictive power was documented by several studies. However, TA measurements require...
Fischer, Matthias, Skowron, Matthias, Berthold, Frank
Real-time reverse transcriptase-polymerase chain reaction (RT-PCR) represents a sensitive and efficient technique to determine expression levels of target genes in multiple samples and is...