Frank Gärtner

Deletion of the RAG2 C terminus leads to impaired lymphoid development in mice

Akamatsu, Yoshiko, Monroe, Robert, Dudley, Darryll D., Elkin, Sheryl K., Gärtner, Frank, Talukder, Sadiqur R., ...

The recombination-activating gene (RAG)1 and RAG2 proteins comprise the lymphocyte-specific components of the V(D)J recombinase and are required for the assembly of antigen-receptor variable-region...

Deletion of the RAG2 C terminus leads to impaired lymphoid development in mice

Akamatsu, Yoshiko, Monroe, Robert, Dudley, Darryll D., Elkin, Sheryl K., Gärtner, Frank, Talukder, Sadiqur R., ...

The recombination-activating gene (RAG)1 and RAG2 proteins comprise the lymphocyte-specific components of the V(D)J recombinase and are required for the assembly of antigen-receptor variable-region...

Allelic Exclusion of the T Cell Receptor β Locus Requires the Sh2 Domain–Containing Leukocyte Protein (Slp)-76 Adaptor Protein

Aifantis, Iannis, Pivniouk, Vadim I., Gärtner, Frank, Feinberg, Jacqueline, Swat, Wojciech, Alt, Frederick W., ...

Signaling via the pre-T cell receptor (TCR) is required for the proliferative expansion and maturation of CD4−CD8− double-negative (DN) thymocytes into CD4+CD8+ double-positive (DP) cells and for...

Antigen-Independent Appearance of Recombination Activating Gene (Rag)-Positive Bone Marrow B Cells in the Spleens of Immunized Mice

Gärtner, Frank, Alt, Frederick W., Monroe, Robert J., Seidl, Katherine J.

Splenic B lineage cells expressing recombination activation genes (RAG+) in mice immunized with 4-hydroxy-3-nitrophenyl-acetyl coupled to chicken γ-globulin (NP-CGG) and the adjuvant...