Frank Gertler

Characterization of EVL-I as a protein kinase D substrate (2009)

De Kimpe, Line, Balsamo, Michele, Vandoninck, Sandy, Gertler, Frank, ...

EVL-I is a splice variant of EVL (Ena/VASP like protein), whose in vivo function and regulation are still poorly understood. We found that Protein Kinase D (PKD) interacts in vitro and in vivo with...

Simultaneous imaging of GFP, CFP and collagen in tumors in vivousing multiphoton microscopy (2005)

Sahai, Erik, Wyckoff, Jeffrey, Philippar, Ulrike, Segall, Jeffrey E, Gertler, Frank, Condeelis, John

Abstract Background The development of multiphoton laser scanning microscopy has greatly facilitated the imaging of living tissues. However, the use of genetically encoded fluorescent proteins to...

The SRF target gene Fhl2 antagonizes RhoA/MAL-dependent activation of SRF (2004)

Philippar,Ulrike, Schratt,Gerhard, Dieterich,Christoph, Müller,Judith M., Galgóczy,Petra, Engel,Felix B., ...

RhoA signaling regulates the activity of the transcription factor SRF (serum response factor) during muscle differentiation. How RhoA signaling is integrated at SRF target promoters to achieve...

The SRF target gene Fhl2 antagonizes RhoA/MAL-dependent activation of SRF (2004)

Philippar, Ulrike, Schratt, Gerhard, Dieterich, Christoph, Müller, Judith M., Galgóczy, Petra, Engel, Felix B., ...

RhoA signaling regulates the activity of the transcription factor SRF (serum response factor) during muscle differentiation. How RhoA signaling is integrated at SRF target promoters to achieve...

A ‘three-pronged’ binding mechanism for the SAP/SH2D1A SH2 domain: structural basis and relevance to the XLP syndrome

Hwang, Peter M., Li, Chengjun, Morra, Massimo, Lillywhite, Jennifer, Muhandiram, D.Ranjith, Gertler, Frank, ...

The SH2 domain protein SAP/SH2D1A, encoded by the X-linked lymphoproliferative (XLP) syndrome gene, associates with the hematopoietic cell surface receptor SLAM in a phosphorylation-independent...

A ‘three-pronged’ binding mechanism for the SAP/SH2D1A SH2 domain: structural basis and relevance to the XLP syndrome

Hwang, Peter M., Li, Chengjun, Morra, Massimo, Lillywhite, Jennifer, Muhandiram, D.Ranjith, Gertler, Frank, ...

The SH2 domain protein SAP/SH2D1A, encoded by the X-linked lymphoproliferative (XLP) syndrome gene, associates with the hematopoietic cell surface receptor SLAM in a phosphorylation-independent...