Frank Sundler

Characterisation of CART-containing neurons and cells in the porcine pancreas, gastro-intestinal tract, adrenal and thyroid glands (2007)

Wierup, Nils, Gunnarsdóttir, Anna, Ekblad, Eva, Sundler, Frank

Abstract Background The peptide CART is widely expressed in central and peripheral neurons, as well as in endocrine cells. Known peripheral sites of expression include the gastrointestinal (GI)...

Sertoli-Leydig Cell Tumour in a Postmenopausal Woman Showing all Facets of the Insulin Resistance Syndrome (IRS) (2007)

Dahlgren, Eva, Gull, Berit, Willén, Roger, Sundler, Frank, Rosén, Thord, Jansson, Per-Anders

Sertoli-Leydig cell tumours are rare sex stromal tumours with an incidence of

DPP-4 inhibition improves glucose tolerance and increases insulin and GLP-1 responses to gastric glucose in association with normalized islet topography in mice with beta-cell-specific overexpression of human islet amyloid polypeptide. (2007)

Ahrén, Bo, Winzell, Maria Sorhede, Wierup, Nils, Sundler, Frank, Burkey, Bryan, Hughes, Thomas E

Abstract is not available

Ghrelin and motilin are co-secreted from a prominent endocrine cell population in the small intestine. (2007)

Wierup, Nils, Bjorkqvist, Maria, Westrom, Bjorn, Pierzynowski, Stefan, Sundler, Frank, Sjolund, Kristina

Abstract is not available

Characterisation of CART-containing neurons and cells in the porcine pancreas, gastro-intestinal tract, adrenal and thyroid glands. (2007)

Wierup, Nils, Gunnarsdóttir, Anna, Ekblad, Eva, Sundler, Frank

Abstract is not available

A Paleolithic diet confers higher insulin sensitivity, lower C-reactive protein and lower blood pressure than a cereal-based diet in domestic pigs (2006)

Jönsson, Tommy, Ahrén, Bo, Pacini, Giovanni, Sundler, Frank, Wierup, Nils, Steen, Stig, ...

Abstract Background A Paleolithic diet has been suggested to be more in concordance with human evolutionary legacy than a cereal based diet. This might explain the lower incidence among...

CART Regulates Islet Hormone Secretion and Is Expressed in the {beta}-Cells of Type 2 Diabetic Rats. (2006)

Wierup, Nils, Bjorkqvist, Maria, Kuhar, Michael J, Mulder, Hindrik, Sundler, Frank

Abstract is not available

Early and rapid development of insulin resistance, islet dysfunction and glucose intolerance after high-fat feeding in mice overexpressing phosphodiesterase 3B. (2006)

Walz, Helena A, Harndahl, Linda, Wierup, Nils, Zmuda-Trzebiatowska, Emilia, Svennelid, Fredrik, Manganiello, Vincent C, ...

Abstract is not available

Oxytocin is expressed throughout the human gastrointestinal tract. (2006)

Ohlsson, Bodil, Truedsson, Mikael, Djerf, Pauline, Sundler, Frank

Abstract is not available

CART is a novel islet regulatory peptide. (2006)

Wierup, Nils, Sundler, Frank

Abstract is not available

Inflammatory response in white adipose tissue in the non-obese hormone-sensitive lipase null mouse model. (2006)

Hansson, Ola, Strom, Kristoffer, Güner, Nuray, Wierup, Nils, Sundler, Frank, Hoglund, Peter, ...

Abstract is not available

Endothelin ETA and ETB receptor expression in the human trigeminal ganglion. (2006)

Uddman, Rolf, Tajti, Janos, Cardell, Lars-Olaf, Sundler, Frank, Uddman, Erik, Edvinsson, Lars

Abstract is not available

A Paleolithic diet confers higher insulin sensitivity, lower C-reactive protein and lower blood pressure than a cereal-based diet in domestic pigs. (2006)

Jonsson, Tommy, Ahrén, Bo, Pacini, Giovanni, Sundler, Frank, Wierup, Nils, Steen, Stig, ...

Abstract is not available

Neuropeptides and the regulation of islet function. (2006)

Ahrén, Bo, Wierup, Nils, Sundler, Frank

Abstract is not available

Progressive Alterations in the Hypothalamic-Pituitary-Adrenal Axis in the R6/2 Transgenic Mouse Model of Huntington's disease (2006)

Björkqvist, Maria, Petersén, Åsa, Bacos, Karl, Isaacs, Jeremy, Norlén, Per, Gil, Joana, ...

Huntington's disease (HD) is characterised by a triad of motor, psychiatric, and cognitive symptoms. While many of these symptoms are likely to be related to central nervous system pathology, others...

Progressive alterations in the hypothalamic-pituitary-adrenal axis in the R6/2 transgenic mouse model of Huntington's disease (2006)

Björkqvist, Maria, Petersén, Åsa, Bacos, Karl, Isaacs, Jeremy, Norlén, Per, Gil, Joana, ...

Huntington's disease (HD) is characterized by a triad of motor, psychiatric and cognitive symptoms. Although many of these symptoms are likely to be related to central nervous system pathology,...

Ultrastructure of islet ghrelin cells in the human fetus. (2005)

Wierup, Nils, Sundler, Frank

Abstract is not available

The R6/2 transgenic mouse model of Huntington's disease develops diabetes due to deficient {beta}-cell mass and exocytosis. (2005)

Björkqvist, Maria, Fex, Malin, Renström, Erik, Wierup, Nils, Petersén, Asa, Gil, Joana, ...

Abstract is not available

Brachioradial pruritus is associated with a reduction in cutaneous innervation that normalizes during the symptom-free remissions. (2005)

Wallengren, Joanna, Sundler, Frank

Abstract is not available

Reduced ghrelin, IAPP and PYY expression in the stomach of gastrin-cholecystokinin knockout mice. (2005)

Friis-Hansen, Lennart, Wierup, Nils, Rehfeld, Jens F, Sundler, Frank

Abstract is not available

Cutaneous field stimulation with moderate intensity current induces nerve proliferation in rat skin but has no effect on dorsal root ganglia. (2005)

Wallengren, Joanna, Moller, Kristian, Sundler, Frank

Abstract is not available

Reduction of GnRH and infertility in the R6/2 mouse model of Huntington's disease. (2005)

Papalexi, Eugenia, Persson, Anna, Bjorkqvist, Maria, Petersén, Asa, Woodman, Ben, Bates, Gillian P, ...

Abstract is not available

The R6/2 transgenic mouse model of Huntington's disease develops diabetes due to deficient {beta}-cell mass and exocytosis (2005)

Björkqvist, Maria, Fex, Malin, Renström, Erik, Wierup, Nils, Petersén, Åsa, Gil, Joana, ...

Diabetes frequently develops in Huntington's disease (HD) patients and in transgenic mouse models of HD such as the R6/2 mouse. The underlying mechanisms have not been clarified. Elucidating the...

Orexin loss in Huntington's disease (2005)

Petersén, Åsa, Gil, Joana, Björkqvist, Maria, Tanila, Heikki, Araújo, Inês M., ...

Huntington's disease (HD) is a devastating neurodegenerative disorder caused by an expanded CAG repeat in the gene encoding huntingtin, a protein of unknown function. Mutant huntingtin forms...

A novel hormone-sensitive lipase isoform expressed in pancreatic beta -cells. (2004)

Lindvall, Hakan, Nevsten, Pernilla, Strom, Kristoffer, Wallenberg, Reine, Sundler, Frank, Langin, Dominique, ...

Hormone-sensitive lipase (HSL) is a key enzyme in fatty acid mobilization in many cell types. Two isoforms of HSL are known to date, namely HSLadi (84 kDa in rat) and HSLtes (130 kDa in rat). These...

Beta-cell-targeted overexpression of phosphodiesterase 3B in mice causes impaired insulin secretion, glucose intolerance and deranged glucose morphology. (2004)

Härndahl, Linda, Wierup, Nils, Enerbäck, Sven, Mulder, Hindrik, Manganiello, Vincent C, Sundler, Frank, ...

Abstract is not available

PACAP mRNA is expressed in rat spinal cord neurons. (2004)

Pettersson, Lina M E, Heine, Tony, Verge, Valerie M K, Sundler, Frank, Danielsen, Nils

Abstract is not available

Loss-of-Function Mutation of the Galanin Gene is Associated with Perturbed Islet Function in Mice. (2004)

Ahren, BO, Pacini, GIOVANNI, Wynick, DAVID, Wierup, NILS, Sundler, FRANK

Abstract is not available

Phototherapy reduces the number of epidermal and CGRP-positive dermal nerve fibres. (2004)

Wallengren, Joanna, Sundler, Frank

Abstract is not available

Effects of high-fat feeding and fasting on ghrelin expression in the mouse stomach. (2004)

Moesgaard, Sophia G, Ahrén, Bo, Carr, Richard D, Gram, Dorte X, Brand, Christian L, Sundler, Frank

Abstract is not available

Orexin loss in Huntington's disease. (2004)

Petersén, Asa, Gil, Joana, Maat-Schieman, Marion Lc, Björkqvist, Maria, Tanila, Heikki, Araújo, Ines M, ...

Abstract is not available

The presence of heme-oxygenase and biliverdin reductase in human cranial ganglia indicates a role for carbon monoxide in neural transmission. (2004)

Uddman, Rolf, Tajti, Janos, Sundler, Frank, Cardell, Lars-Olaf

Abstract is not available

Decreased UCP2 mRNA expression in rat stomach following vagotomy: novel role for UCP2 as free radical scavenger in the stomach? (2004)

Lindqvist, Andreas, Mei, Jie, Sundler, Frank, Erlanson-Albertsson, Charlotte

Abstract is not available

Orexin loss in Huntington's disease (2004)

Petersén, Åsa, Gil, Joana, Maat-Schieman, Marion LC, Björkqvist, Maria, Tanila, Heikki, Araújo, Ines M, ...

Huntington's disease is a devastating neurodegenerative disorder caused by an expanded CAG repeat in the gene encoding huntingtin, a protein of unknown function. Mutant huntingtin forms intracellular...

Orexin loss in Huntington's disease (2004)

Petersén, Åsa, Gil, Joana, Maat-Schieman, Marion LC, Björkqvist, Maria, Tanila, Heikki, Araújo, Ines M, ...

Huntington's disease is a devastating neurodegenerative disorder caused by an expanded CAG repeat in the gene encoding huntingtin, a protein of unknown function. Mutant huntingtin forms intracellular...

Neural expression and increased lavage fluid levels of secretoneurin in seasonal allergic rhinitis. (2003)

Korsgren, Magnus, Erjefalt, Jonas S, Hinterholzl, Josef, Fischer-Colbrie, Reiner, Ahlstrom Emanuelsson, Cecilia, Andersson, Morgan, ...

Abstract is not available

Hormone-sensitive lipase null mice exhibit signs of impaired insulin sensitivity whereas insulin secretion is intact. (2003)

Mulder, Hindrik, Sorhede-Winzell, Maria, Contreras, Juan Antonio, Fex, Malin, Strom, Kristoffer, Ploug, Thorkil, ...

Abstract is not available

Pancreatic beta-Cell Lipotoxicity Induced by Overexpression of Hormone-Sensitive Lipase. (2003)

Sörhede Winzell, Maria, Svensson, Håkan, Enerbäck, Sven, Ravnskjaer, Kim, Mandrup, Susanne, Esser, Victoria, ...

Abstract is not available

Mucosal Expression and Lavage Fluid Levels of Secretoneurin in Seasonal Allergic Rhinitis. (2003)

Korsgren, Magnus, Erjefalt, Jonas S., Hinterholzl, Josef, Fischer-Colbrie, Reiner, Emanuelsson, Cecilia Ahlstrom, Andersson, Morgan, ...

Yes

Mucosal Expression and Lavage Fluid Levels of Secretoneurin in Seasonal Allergic Rhinitis. (2003)

Korsgren, Magnus, Erjefalt, Jonas S., Hinterholzl, Josef, Fischer-Colbrie, Reiner, Emanuelsson, Cecilia Ahlstrom, Andersson, Morgan, ...

Yes

Mucosal Expression and Lavage Fluid Levels of Secretoneurin in Seasonal Allergic Rhinitis. (2003)

Korsgren, Magnus, Erjefalt, Jonas S., Hinterholzl, Josef, Fischer-Colbrie, Reiner, Emanuelsson, Cecilia Ahlstrom, Andersson, Morgan, ...

Neural Expression and Increased Lavage Fluid Levels of Secretoneurin in Seasonal Allergic Rhinitis (2003)

Korsgren, Magnus, Erjefalt, Jonas S., Hinterholzl, Josef, Fischer-Colbrie, Reiner, Emanuelsson, Cecilia Ahlstrom, Andersson, Morgan, ...

Secretoneurin is a neuropeptide potentially involved in migration of eosinophils, monocytes, and dendritic cells. Whether secretoneurin is present in the human airway mucosa and whether it is...

Effects of chemical sympathectomy by means of 6-hydroxydopamine on insulin secretion and islet morphology in alloxan-diabetic mice. (2002)

Kvist-Reimer, Martina, Sundler, Frank, Ahrén, Bo

Abstract. Activation of sympathetic nerves increases circulating glucose and inhibits insulin release from the islet beta-cells, which might contribute to stress-related diabetes. Accordingly, we...

Distribution of pancreatic polypeptide and peptide YY. (2002)

Ekblad, Eva, Sundler, Frank

The cellular distribution of PP and PYY in mammals is reviewed. Expression of PP is restricted to endocrine cells mainly present in the pancreas predominantly in the duodenal portion (head) but also...

Cutaneous sensory nerve fibers are decreased in number after peripheral and central nerve damage. (2002)

Wallengren, Joanna, Tegner, Eva, Sundler, Frank

Two dermatologic patients displaying peripheral and central nerve damage, respectively, are described. Cutaneous nerve fibers in both patients were studied in skin biopsy specimens taken from...

Eosinophil infiltration and activation at the gastric ulcer margin in rats. (2002)

Mei, Qi, Korsgren, Magnus, Erjefält, Jonas S, Sundler, Frank

BACKGROUND : Recruitment and activation of eosinophils have been studied intensely in asthma and other allergic diseases. Less is known about the infiltration and behaviour of eosinophils during...

Expression of orphanin FQ/nociceptin and its receptor in rat peripheral ganglia and spinal cord. (2002)

Pettersson, Lina M E, Sundler, Frank, Danielsen, Nils

Expression of the neuropeptide orphanin FQ/nociceptin (OFQ/N) and its receptor, the opioid receptor-like receptor (ORL1), have been found to have a wide distribution in the central nervous system,...

Islet function phenotype in gastrin-releasing Peptide receptor gene-deficient mice. (2002)

Persson, Kristin, Pacini, Giovanni, Sundler, Frank, Ahrén, Bo

Gastrin-releasing peptide (GRP) is an islet neuropeptide that stimulates insulin secretion. To explore whether islet GRP contributes to neurally mediated insulin secretion, we studied GRP receptor...

Histochemistry of fluorogenic amines and peptides with NH₂-terminal tryptophan in polypeptide hormone-secreting cells : with special reference to the calcitonin cells / (1973)

Sundler, Frank.

Thesis (doctoral)--University of Lund, 1973.

A Paleolithic diet confers higher insulin sensitivity, lower C-reactive protein and lower blood pressure than a cereal-based diet in domestic pigs

Jönsson, Tommy, Ahrén, Bo, Pacini, Giovanni, Sundler, Frank, Wierup, Nils, Steen, Stig, ...

Alterations in regulation of energy homeostasis in cyclic nucleotide phosphodiesterase 3B–null mice

Choi, Young Hun, Park, Sunhee, Hockman, Steven, Zmuda-Trzebiatowska, Emilia, Svennelid, Fredrik, Haluzik, Martin, ...

Cyclic nucleotide phosphodiesterase 3B (PDE3B) has been suggested to be critical for mediating insulin/IGF-1 inhibition of cAMP signaling in adipocytes, liver, and pancreatic β cells. In Pde3b-KO...

A Paleolithic diet confers higher insulin sensitivity, lower C-reactive protein and lower blood pressure than a cereal-based diet in domestic pigs

Jönsson, Tommy, Ahrén, Bo, Pacini, Giovanni, Sundler, Frank, Wierup, Nils, Steen, Stig, ...

Alterations in regulation of energy homeostasis in cyclic nucleotide phosphodiesterase 3B–null mice

Choi, Young Hun, Park, Sunhee, Hockman, Steven, Zmuda-Trzebiatowska, Emilia, Svennelid, Fredrik, Haluzik, Martin, ...

Cyclic nucleotide phosphodiesterase 3B (PDE3B) has been suggested to be critical for mediating insulin/IGF-1 inhibition of cAMP signaling in adipocytes, liver, and pancreatic β cells. In Pde3b-KO...

Characterisation of CART-containing neurons and cells in the porcine pancreas, gastro-intestinal tract, adrenal and thyroid glands

Wierup, Nils, Gunnarsdóttir, Anna, Ekblad, Eva, Sundler, Frank

Attainment of Brown Adipocyte Features in White Adipocytes of Hormone-Sensitive Lipase Null Mice

Ström, Kristoffer, Hansson, Ola, Lucas, Stéphanie, Nevsten, Pernilla, Fernandez, Céline, Klint, Cecilia, ...

Natural Killer Cells Determine Development of Allergen-induced Eosinophilic Airway Inflammation in Mice

Korsgren, Magnus, Persson, Carl G.A., Sundler, Frank, Bjerke, Torbjörn, Hansson, Tony, Chambers, Benedict J., ...

The earliest contact between antigen and the innate immune system is thought to direct the subsequent antigen-specific T cell response. We hypothesized that cells of the innate immune system, such as...

Allergic Eosinophil-rich Inflammation Develops in Lungs and Airways of B Cell–deficient Mice

Korsgren, Magnus, ält, Jonas S. Erjef, Korsgren, Olle, Sundler, Frank, Persson, Carl G.A.

Immunoglobulins (Ig), particularly IgE, are believed to be crucially involved in the pathogenesis of asthma and, equally, in allergic models of the disease. To validate this paradigm we examined...