Aberrant methylation of candidate tumor suppressor genes in neuroblastoma (2009)
Hoebeeck, Jasmien,
MICHELS, EVELIEN,
Pattyn, Filip,
Combaret, Valerie,
Vermeulen, Joelle,
Yigit, Nurten,
...
CpG island hypermethylation has been recognized as an alternative mechanism for tumor suppressor gene inactivation. In this study, we performed methylation-specific PCR (MSP) to investigate the...
Unusual 8p inverted duplication deletion with telomere capture from 8q (2009)
Buysse, Karen,
Antonacci, F,
CALLEWAERT, BERT,
Loeys, Bart,
Fränkel, Ulrike,
Siu, Victoria,
...
Inverted 8p duplication deletions are recurrent chromosomal rearrangements that are mediated through non-allelic homologous recombination (NAHR) between olfactory receptor (OR) gene clusters at...
Genome profiling of acute myelomonocytic leukemia: alteration of the MYB locus in MYST3-linked cases (2009)
Murati, A,
Gervais, C,
Carbuccia, N,
Finetti, P,
Cervera, N,
Adelaide, J,
...
The t(8; 16)(p11; p13) is a rare translocation involved in de novo and therapy-related myelomonocytic and monocytic acute leukemia. It fuses two genes encoding histone acetyltransferases (HATs),...
The 12q14 microdeletion syndrome: additional patients and further evidence that HMGA2 is an important genetic determinant for human height (2009)
Buysse, Karen,
Reardon, William,
Mehta, Lakshmi,
Costa, Teresa,
Fagerstrom, Carrie,
Kingsbury, Daniel J.,
...
Characteristic features of the 12q14 microdeletion syndrome include low birth weight, failure to thrive, short stature, learning disabilities and Buschke-Ollendorff lesions in bone and skin. This...
Identification of 2 putative critical segments of 17q gain in neuroblastoma through integrative genomics (2008)
Vandesompele, Jo,
Michels, Evi,
De Preter, Katleen,
Menten, Björn,
SCHRAMM, A,
EGGERT, A,
...
Hyperdiploid karyotypes in acute myeloid leukemia define a novel entity: a study of 38 patients from the Groupe Francophone de Cytogenetique Hematologique (GFCH) (2008)
LUQUET, I,
LAI, JL,
BARIN, C,
BARANGER, L,
BILHOU-NABERA, C,
LIPPERT, E,
...
Evaluation of EGFR and K-RAS gene status in squamous cell carcinoma of the anal canal. (2008)
VAN DAMME, NANCY,
Van Roy, Nadine,
Speleman, Franki,
BOLS, A,
VAN DORPE, J,
Pauwels, Patrick,
...
EGFR and K-RAS gene status in squamous cell carcinoma of the anal canal (2008)
VAN DAMME, NANCY,
Van Roy, Nadine,
Demetter, Pieter,
Speleman, Franki,
BOLS, A,
VAN DORPE, J,
...
Unmasking of epigenetically silenced micromas in neuroblastoma (2008)
Hoebeeck, Jasmien,
Declerck, Geert,
Mestdagh, Pieter,
Pattyn, Filip,
De Preter, Katleen,
Vermeulen, Joëlle,
...
EVII activation in blast crisis CML due to juxtaposition to the rare 17q22 partner region as part of a 4-way variant translocation t(9;22) (2008)
De Weer, An,
Poppe, Bruce,
Cauwelier, Barbara,
CARLIER, A,
DIERICK, J,
Verhasselt, Bruno,
...
Background: Variant translocations t( 9; 22) occur in 5 to 10% of newly diagnosed CMLs and additional genetic changes are present in 60 - 80% of patients in blast crisis ( BC). Here, we report on a...
Delineation of a critical region on chromosome 18 for the del(18)(q12.2q21.1) syndrome (2008)
Buysse, Karen,
Menten, Björn,
Oostra, Ann,
TAVERNIER, S,
Mortier, Geert,
Speleman, Franki
CADM1 is a strong neuroblastoma candidate gene that maps within a 3.72 Mb critical region of loss on 11q23 (2008)
Michels, Evi,
Hoebeeck, Jasmien,
De Preter, Katleen,
SCHRAMM, A,
BRICHARD, B,
De Paepe, Anne,
...
Unmasking of epigenetically silenced micromas in neuroblastoma (2008)
Hoebeeck, Jasmien,
Declerck, Geert,
Mestdagh, Pieter,
Pattyn, Filip,
De Preter, Katleen,
Vermeulen, Joëlle,
...
Recurrent rearrangements of chromosome 1q21.1 and variable pediatric phenotypes (2008)
MEFFORD, HC,
SHARP, AJ,
BAKER, C,
ITSARA, A,
JIANG, ZS,
Buysse, Karen,
...
Mapping of 5q35 chromosomal rearrangements within a genomically unstable region (2008)
Buysse, Karen,
CREPEL, A,
Menten, Björn,
Pattyn, Filip,
ANTONACCI, F,
VELTMAN, J,
...
Background: Recent molecular studies of breakpoints of recurrent chromosome rearrangements revealed the role of genomic architecture in their formation. In particular, segmental duplications...
Delineation of a critical region on chromosome 18 for the del (18)(q12.2q21.1) syndrome (2008)
Buysse, Karen,
Menten, Björn,
Oostra, Ann,
TAVERNIER, S,
Mortier, Geert,
Speleman, Franki
Identification of ALK as a major familial neuroblastoma predisposition gene (2008)
MOSSE, YP,
LAUDENSLAGER, M,
LONGO, L,
COLE, KA,
WOOD, A,
ATTIYEH, EF,
...
Low-cost dedicated mini-arrays for high-throughput analysis of DNA copy-number alterations in neuroblastoma (2008)
De Preter, Katleen,
Menten, Björn,
De Brouwer, Sara,
Kumps, Candy,
Michels, Evi,
Van Roy, Nadine,
...
Acute myeloid leukaemia with 8p11 (MYST3) rearrangement: an integrated cytologic, cytogenetic and molecular study by the groupe francophone de cytogenetique de hematologique (2008)
GERVAIS, C,
MURATI, A,
HELIAS, C,
STRUSKI, S,
EISCHEN, A,
LIPPERT, E,
...
A constitutional translocation t(1;17)(p36.2;q11.2) in a neuroblastoma patient disrupts the the human NBPF1 and ACCN1 genes (2008)
Van Roy, Frans,
Vandepoele, Karl,
Van Roy, Nadine,
Andries, Vanessa,
Staes, Katrien,
Vandesompele, Jo,
...
High-throughput stem-loop RT-qPCR miRNA expression profiling using minute amounts of input RNA (2008)
Mestdagh, Pieter,
Feys, Tom,
Bernard, Nathalie,
Guenther, Simone,
Chen, Caifu,
Speleman, Franki,
...
EVI1 overexpression in t(3;17) positive myeloid malignancies results from juxtaposition of EVI1 to the MSI2 locus at 17q22 (2008)
De Weer, An,
Speleman, Franki,
Cauwelier, Barbara,
Van Roy, Nadine,
Yigit, Nurten,
Verhasselt, Bruno,
...
Chromosomal translocations involving the EVI1 locus are a recurrent finding in myeloid leukemia and are associated with poor prognosis. In this study, we performed a detailed molecular...
MICRORNA PROFILING OF EVI1 DEREGULATED MYELOID LEUKEMIA (2008)
De Weer, An,
Poppe, Bruce,
Mestdagh, Pieter,
Van Vlierberghe, Pieter,
Van Roy, Nadine,
De Paepe, Anne,
...
EVII activation in blast crisis CML due to juxtaposition to the rare 17q22 partner region as part of a 4-way variant translocation t(9;22) (2008)
De Weer, An,
Poppe, Bruce,
Cauwelier, Barbara,
Carlier, Andre,
Dierick, Jan,
Verhasselt, Bruno,
...
Background: Variant translocations t( 9; 22) occur in 5 to 10% of newly diagnosed CMLs and additional genetic changes are present in 60 - 80% of patients in blast crisis ( BC). Here, we report on a...
EVI1 overexpression in t(3;17) positive myeloid malignancies results from juxtaposition of EVI1 to the MSI2 locus at 17q22 (2008)
De Weer, An,
Speleman, Franki,
Cauwelier, Barbara,
Van Roy, Nadine,
Yigit, Nurten,
Verhasselt, Bruno,
...
Chromosomal translocations involving the EVI1 locus are a recurrent finding in myeloid leukemia and are associated with poor prognosis. In this study, we performed a detailed molecular...
A Constitutional Translocation t(1;17)(p36.2;q11.2) in a Neuroblastoma Patient Disrupts the Human NBPF1 and ACCN1 Genes (2008)
Vandepoele, Karl,
Andries, Vanessa,
Van Roy, Nadine,
Staes, Katrien,
Vandesompele, Jo,
Laureys, Genevieve,
...
MicroRNA signatures in genetic subtypes of T-cell acute lymphoblastic leukemia. (2008)
Van Vlierberghe, Pieter,
Poppe, Bruce,
Van Roy, Nadine,
Taghon, Tom,
Plum, Jean,
Cauwelier, B,
...
Copy number alterations and copy number variation in cancer: close encounters of the bad kind (2008)
Speleman, Franki,
Kumps, Candy,
Buysse, Karen,
Poppe, Bruce,
Menten, Björn,
De Preter, Katleen
Recent studies have unveiled copy number variants (CNVs) as an important source of genetic variation. Many of these CNVs contain coding sequences, which have been shown to be dosage sensitive....
Real-time qPCR as a tool for evaluating RNAi-mediated gene silencing (2008)
Van Maerken, Tom,
Mestdagh, Pieter,
De Clercq, Sarah,
Pattyn, Filip,
Yigit, Nurten,
De Paepe, Anne,
...
This article describes how rt-qPCR can be implemented as a tool to monitor silencing efficiency and functional effects of RNA interference (RNAi)-mediated gene knockdown, using examples from our...
High resolution tiling-path BAC array deletion mapping suggests commonly involved 3p21-p22 tumor suppressor genes in neuroblastoma and more frequent tumors (2007)
Hoebeeck, Jasmien,
Michels, Evi,
Menten, Björn,
Van Roy, Nadine,
EGGERT, A,
SCHRAMM, A,
...
A detailed inventory of DNA copy number alterations in four commonly used Hodgkin's lymphoma cell lines (2007)
Feys, Tom,
Poppe, Bruce,
De Preter, Katleen,
Van Roy, Nadine,
Verhasselt, Bruno,
DE PAEPE, P,
...
Genome wide promoter methylation analysis in neuroblastoma with perspectives for integrated molecular profiling (2007)
Hoebeeck, Jasmien,
Ongenaert, Maté,
Michels, Evi,
De Preter, Katleen,
Vermeulen, Joëlle,
Yigit, Nurten,
...
Array CGH analysis of subnanogram quantities of DNA using whole genome amplification: Opportunities for detection of copy number alterations in Hodgkin's lymphoma (2007)
Feys, Tom,
Poppe, Bart,
Verhasselt, Bruno,
De Paepe, Pascale,
Menten, Björn,
Vandesompele, Jo,
...
ArrayCGH-based classification of neuroblastoma into genomic subgroups (2007)
Michels, Evi,
Vandesompele, Jo,
De Preter, Katleen,
Hoebeeck, Jasmien,
Vermeulen, Joëlle,
SCHRAMM, A,
...
Integrative genomics in neuroblastoma research (2007)
Speleman, Franki,
De Preter, Katleen,
Michels, Evi,
Hoebeeck, Jasmien,
Pattyn, Filip,
VERTMEULEN, J,
...
ArrayCGH based classification of neuroblastoma into genomic subgroups (2007)
De Brouwer, Sara,
Michels, Evi,
Vandesompele, Jo,
De Preter, Katleen,
Hoebeeck, Jasmien,
Vermeulen, Joëlle,
...
Identification of EVI1 transcriptional target genes using RNAI (2007)
De Weer, An,
Poppe, Bruce,
CAUWEUER, B,
Van Roy, Nadine,
Verhasselt, Bruno,
Speleman, Franki
A detailed inventory of DNA copy number alterations in four commonly used Hodgkin lymphoma cell lines (2007)
Feys, Tom,
Poppe, Bruce,
De Preter, Katleen,
Van Roy, Nadine,
Verhasselt, Bruno,
De Paepe, Pascale,
...
Subtelomeric imbalances in phenotypically normal individuals (2007)
BALIKOVA, I,
Menten, Björn,
DE RAVEL, T,
LE CAIGNEC, C,
THIENPONT, B,
URBINA, M,
...
MicroRNA profiling of EVI1 deregulated myeloid leukemia (2007)
De Weer, An,
Poppe, Bruce,
Mestdagh, Pieter,
Van Roy, Nadine,
De Paepe, Anne,
Verhasselt, Bruno,
...
International consensus for neuroblastoma molecular diagnostics: report from the international neuroblastoma risk grouping (INRG) biology committee (2007)
AMBROS, PF,
AMBROS, IM,
BRODEUR, GM,
HABER, M,
KHAN, J,
NAKAGAWARA, A,
...
Guidelines for molecular karyotyping in constitutional genetic diagnosis (2007)
VERMEESCH, JR,
FIEGLER, H,
DE LEEUW, N,
SZUHAI, K,
SCHOUMANS, J,
CICCONE, R,
...
Report of an unusual translocation t(3;14)(q26;q32) involving both EVI1 and IGH in an unclassified acute myeloid leukaemia (AML) (2007)
HAVELANGE, V,
AMEYE, G,
DEWEER, A,
BAHLOULA, K,
MULLIER, C,
LIBOUTON, JM,
...
RANBP17-TLX3: A hot spot region for both constitutional and acquired rearrangements (2007)
Buysse, Karen,
Menten, Björn,
ANTONACCI, F,
VELTMAN, JA,
LARSEN, LA,
TUMER, Z,
...
Duplication and rearrangement of the MYB oncogene in T-cellacute lymphoblastic leukemia (2007)
LAHORTIGA, I,
Cauwelier, Barbara,
DEKEERSMAECKER, K,
VAN VLIEBERGHE, P,
GRAUX, C,
LAMBERT, F,
...
Molecular dissection of isolated disease features in mosaic neurofibromatosis type 1 (2007)
Maertens, Ophélia,
DE SCHEPPER, S,
Vandesompele, Jo,
BRERNS, H,
HEYNS, I,
JANSSENS, SANDRA,
...
Mapping biomedical concepts onto the human genome by mining literature on chromosomal aberrations (2007)
VAN VOOREN, S,
THIENPONT, B,
Menten, Björn,
Speleman, Franki,
DE MOOR, B,
VERMEESCH, J,
...
Report of 38 patients with hyperdiploid karyotype in acute myeloid leukemia: A groupe francais de cytogenetique hematologique study (2007)
TERRE, C,
LUQUET, I,
LAI, JL,
BARIN, C,
BARANGER, L,
BILHOU-NABERA, C,
...
Translating expression profiling into a clinically feasible test to predict neuroblastoma outcome (2007)
SCHRAMM, A,
Vandesompele, Jo,
SCHULTE, JH,
DREESMANN, S,
KADERALI, L,
BRORS, B,
...
Real-time PCR quality control for gene expression profiling on the LightCycler 480 System (2007)
Hoebeeck, Jasmien,
Pattyn, Filip,
NURTEN, Y,
DE SMET, E,
Speleman, Franki,
Vandesompele, Jo
Array CGH based classification of neuroblastoma into genomic subgroups. (2007)
De Brouwer, Sara,
Michels, Evi,
Vandesompele, Jo,
De Preter, Katleen,
Hoebeeck, Jasmien,
VERMEULEN, J,
...
Array CGH analysis of subnanogram quantities of DNA using whole genome amplification: Opportunities for detection of copy number alterations in Hodgkin's lymphoma (2007)
Feys, Tom,
Poppe, Bruce,
Verhasselt, Bruno,
DE PAEPE, P,
Menten, Björn,
Vandesompele, Jo,
...
Osteopoikilosis, short stature and mental retardation as key features of a new microdeletion syndrome on 12q14 (2007)
Menten, Björn,
Buysse, Karen,
ZAHIR, F,
Hellemans, Jan,
HAMILTON, SJ,
COSTA, T,
...
Report of a female patient with mental retardation and tall stature due to a chromosomal rearrangement disrupting the OPHN1 gene on Xq12 (2007)
Menten, Björn,
Buysse, Karen,
Vermeulen, Stefan,
Meersschaut, Valerie,
Vandesompele, Jo,
NG, BL,
...
Clinical, cytogenetic and molecular characteristics of 14 T-ALL patients carrying the TCR beta-HOXA rearrangement: a study of the Groupe Francophone de Cytogenetique Hematologique (2007)
Cauwelier, Barbara,
CAVÉ, H,
GERVAIS, C,
LESSARD, M,
BARIN, C,
PEROT, C,
...
Clinical, cytogenetic and molecular characteristics of 14 T-ALL patients carrying the TCRb-HOXA rearrangement : a study of the Groupe Francophone de Cytogénétique Hématologique (GFCH). (2007)
Cauwelier, B,
Cavé, H,
Gervais, C,
Lessard, M,
Barin, C,
Perot, C,
...
Recently, we and others described a new chromosomal rearrangement, that is, inv( 7)( p15q34) and t( 7; 7)( p15; q34) involving the T-cell receptor beta ( TCR beta) ( 7q34) and the HOXA gene locus (...
Duplication of the MYB oncogene in T cell acute lymphoblastic leukemia (2007)
Lahortiga, Idoya,
De Keersmaecker, Kim,
Van Vlierberghe, Pieter,
Graux, Carlos,
Cauwelier, Barbara,
Lambert, Frederic,
...
We identified a duplication of the MYB oncogene in 8.4% of individuals with T cell acute lymphoblastic leukemia (T-ALL) and in five T-ALL cell lines. The duplication is associated with a threefold...
GAB2 is a novel target of 11q amplification in AML/MDS (2006)
ZATKOVA, A,
SCHOCH, C,
Speleman, Franki,
Poppe, Bruce,
MANNHALTER, C,
FONATSCH, C,
...
Molecular cytogenetic study of 126 unselected T-ALL cases reveals high incidence of TCR beta locus rearrangements and putative new T-cell oncogenes (2006)
Cauwelier, Barbara,
DASTUGUE, N,
COOLS, J,
Poppe, Bruce,
HERENS, C,
De Paepe, Anne,
...
Translocation-excision-deletion-amplification mechanism leading to nonsyntenic coamplification of MYC and ATBF1 (2006)
Van Roy, Nadine,
Vandesompele, Jo,
Menten, Björn,
NILSSON, H,
De Smet, Els,
ROCCHI, M,
...
EVII is consistently expressed as principal transcript in common and rare recurrent 3q26 rearrangements (2006)
Poppe, Bruce,
DASTUGUE, N,
Vandesompele, Jo,
Cauwelier, Barbara,
DE SMET, B,
Yigit, Nurten,
...
Comprehensive NF1 screening on cultured Schwann cells from neurofibromas (2006)
Maertens, Ophélia,
BREMS, H,
Vandesompele, Jo,
DE RAEDT, T,
HEYNS, I,
ROSENBAUM, T,
...
Somatic loss of wild type NF1 allele in neurofibromas: Comparison of NF1 microdeletion and non-microdeletion patients (2006)
DE RAEDT, T,
Maertens, Ophélia,
CHMARA, M,
BREMS, H,
HEYNS, I,
SCIOT, R,
...
Molecular pathogenesis of multiple gastrointestinal stromal tumors in NF1 patients (2006)
Maertens, Ophélia,
PRENEN, H,
WOZNIAK, A,
SCIOT, R,
Pauwels, Patrick,
DE WEVER, I,
...
Emerging patterns of cryptic chromosomal imbalance in patients with idiopathic mental retardation and multiple congenital anomalies: a new series of 140 patients and review of published reports (2006)
Menten, Björn,
MAAS, N,
THIENPONT, B,
Buysse, Karen,
Vandesompele, Jo,
MELOTTE, C,
...
Recurrent T(3;17)translocations in AML with EVI1 rearrangement (2006)
De Weer, An,
Poppe, Bruce,
Cauwelier, Barbara,
Van Roy, Nadine,
DASTUGUE, N,
De Moerloose, Barbara,
...
The TCRB-HOXA rearrangement in T-ALL leads to a specific increase of the alternative HOXA10b transcript (2006)
Cauwelier, Barbara,
CAVÉ, H,
DASTUGUE, N,
HEIMANN, P,
ANTOINE-POIREL, H,
Verhasselt, Bruno,
...
Screening for EVII: ectopic expression absent in T-cell acute lymphoblastic leukemia patients and cell lines (2006)
De Weer, An,
Poppe, Bruce,
Cauwelier, Barbara,
Van Roy, Nadine,
DASTUGUE, N,
HAGEMEIJER, A,
...
The von Hippel-Lindau tumor suppressor gene expression level has prognostic value in neuroblastoma (2006)
Hoebeeck, Jasmien,
Vandesompele, Jo,
NILSSON, H,
De Preter, Katleen,
Van Roy, Nadine,
De Smet, Els,
...
Culturing in vitro produced blastocysts in sequential media promotes ES cell derivation (2006)
Liu, Jun,
Schoonjans, Lore,
Tielens, Severine,
Speleman, Franki,
Cornelissen, Maria,
De Sutter, Petra,
...
RTPrimerDB: the real-time PCR primer and probe database, major update 2006 (2006)
Pattyn, Filip,
Robbrecht, Piet,
De Paepe, Anne,
Speleman, Franki,
Vandesompele, Jo
Small-molecule MDM2 antagonists as a new therapy concept for neuroblastoma (2006)
Van Maerken, Tom,
Speleman, Franki,
VERMEULEN, J,
LAMBERTZ, I,
DE CLERCQ, S,
De Smet, Els,
...
MethBLAST and methPrimerDB: web-tools for PCR based methylation analysis (2006)
Pattyn, Filip,
Hoebeeck, Jasmien,
Robbrecht, Piet,
Michels, Evi,
De Paepe, Anne,
BOTTU, G,
...
Expression profiling suggests underexpression of the GABA(A) receptor subunit delta in the fragile X knockout mouse model (2006)
GANTOIS, I,
Vandesompele, Jo,
Speleman, Franki,
REYNIERS, E,
D'HOOGE, R,
SEVERIJNEN, LA,
...
Human fetal neuroblast and neuroblastoma transcriptome analysis confirms neuroblast origin and highlights neuroblastoma candidate genes (2006)
De Preter, Katleen,
Vandesompele, Jo,
HEIMANN, P,
Yigit, Nurten,
BECKMAN, S,
SCHRAMM, A,
...
Genome wide measurement of DNA copy number changes in neuroblastoma: dissecting amplicons and mapping losses, gains and breakpoints (2006)
Michels, Evi,
Vandesompele, Jo,
Hoebeeck, Jasmien,
Menten, Björn,
De Preter, Katleen,
Laureys, Genevieve,
...
Recurrent t(3;17) translocations in AML with EVII rearrangement. (2006)
De Weer, A,
Poppe, Bruce,
Cauwelier, B,
Van Roy, Nadine,
Dastugue, N,
De Moerloose, Barbara,
...
Comprehensive NF1 screening on cultured Schwann cells from neurofibromas: towards an extensive study of the somatic mutation spectrum in neurofibromatosis type 1 (2006)
Maertens, Ophélia,
Brems, Hilde,
Vandesompele, Jo,
De Raedt, Thomas,
Heyns, Ine,
Rosenbaum, Thorsten,
...
Neurofibromatosis type 1 (NF1) is mainly characterized by the occurrence of benign peripheral nerve sheath tumors or neurofibromas. Thorough investigation of the somatic mutation spectrum has thus...
Unequivocal delineation of clinicogenetic subgroups and development of a new model for improved outcome prediction in neuroblastoma (2005)
Vandesompele, Jo,
BAUDIS, M,
De Preter, Katleen,
Van Roy, Nadine,
AMBROS, P,
BOWN, N,
...
Molecular karyotyping: Array CGH quality criteria for constitutional genetic diagnosis (2005)
VERMEESCH, JR,
MELOTTE, C,
FROYEN, G,
VAN VOOREN, S,
DUTTA, B,
MAAS, N,
...
Familial pericentric inversion of chromosome 18: behavioral abnormalities in patients heterozygous for either the dup(18p)/del(18q) or dup(18q)/del(18p) recombinant chromosome (2005)
Vermeulen, Stefan,
Speleman, Franki,
VANRANSBEECK, L,
Verspeet, Jasmine,
Menten, Björn,
VERSCHRAEGEN-SPAE, MR,
...
arrayCGHbase: an analysis platform for comparative genomic hybridization microarrays (2005)
Menten, Björn,
Pattyn, Filip,
De Preter, Katleen,
Robbrecht, Piet,
Michels, Evi,
Buysse, Karen,
...
Identification of an unbalanced X-autosome translocation by array CGH in a boy with a syndromic form of chondrodysplasia punctata brachytelephalangic type (2005)
Menten, Björn,
Buysse, Karen,
Vandesompele, Jo,
De Smet, Els,
De Paepe, Anne,
Speleman, Franki,
...
Positional and functional mapping of a neuroblastoma differentiation gene on chromosome 11 (2005)
De Preter, Katleen,
Vandesompele, Jo,
Menten, Björn,
CARR, P,
FIEGLER, H,
EDSJO, A,
...
Rapid detection of VHL exon deletions using real-time quantitative PCR (2005)
Hoebeeck, Jasmien,
Poppe, Bruce,
De Smet, Els,
Yigit, Nurten,
Claes, Kathleen,
...
A new recurrent inversion, inv(7)(p15q34), leads to transcriptional activation of HOXA10 and HOXA11 in a subset of T-cell acute lymphoblastic leukemias (2005)
Speleman, Franki,
Cauwelier, Barbara,
DASTUGUE, N,
COOLS, J,
Verhasselt, Bruno,
Poppe, Bruce,
...
Novel cryptic chromosomal rearrangements in childhood acute lymphoblastic leukemia detected by multiple color fluorescent in situ hybridization (2005)
Poppe, Bruce,
Cauwelier, Barbara,
VAN LIMBERGEN, H,
Yigit, Nurten,
Philippe, Jan,
Verhasselt, Bruno,
...
HOYA gene cluster rearrangement in a t(7;9)(p15;q34) in a child with MDS (2005)
Poppe, Bruce,
Yigit, Nurten,
De Moerloose, Barbara,
De Paepe, Anne,
Benoit, Yves,
Speleman, Franki
PAX5/IGH rearrangement is a recurrent finding in a subset of aggressive B-NHL with complex chromosomal rearrangements (2005)
Poppe, Bruce,
DE PAEPE, P,
MICHAUX, L,
DASTUGUE, N,
BASTARD, C,
HERENS, C,
...
No evidence for correlation of DDX1 gene amplification with improved survival probability in patients with MYCN-amplified neuroblastomas (2005)
De Preter, Katleen,
Speleman, Franki,
COMBARET, V,
LUNEC, J,
BOARD, J,
PEARSON, A,
...
Impact of RNA quality on reference gene expression stability (2005)
PEREZ-NOVO, CA,
Claeys, Cindy,
Speleman, Franki,
Van Cauwenberge, Paul,
Bachert, Claus,
Vandesompele, Jo
Combined subtractive cDNA cloning and array CGH: an efficient approach for identification of overexpressed genes in DNA amplicons (2004)
De Preter, Katleen,
Pattyn, Filip,
Berx, Geert,
Strumane, Kristin,
Menten, Björn,
Van Roy, Frans,
...
Expression analyses identify MLL as a prominent target of 11q23 amplification and support an etiologic role for MLL gain of function in myeloid malignancies (2004)
Poppe, Bruce,
Vandesompele, Jo,
SCHOCH, C,
LINDVALL, C,
MROZEK, K,
BLOOMFIELD, CD,
...
Molecular cytogenetic analysis of complex chromosomal rearrangements in patients with mental retardation and congenital malformations: Delineation of 7q21.11 breakpoints (2004)
Vermeulen, Stefan,
Menten, Björn,
Van Roy, Nadine,
VAN LIMBERGEN, H,
De Paepe, Anne,
Mortier, Geert,
...
Clinical significance of HOX11L2 expression linked to t(5;14)(q35;q32), of HOX11 expression, and of SIL-TAL fusion in childhood T-cell malignancies: results of EORTC studies 58881 and 58951 (2004)
CAVÉ, H,
SUCIU, S,
PREUDHOMME, C,
Poppe, Bruce,
ROBERT, A,
UYTTEBROECK, A,
...
Gene-expression profiling reveals distinct expression patterns for classic versus variant Merkel cell phenotypes and new classifier genes to distinguish Merkel cell from small-cell lung carcinoma (2004)
VAN GELE, M,
BOYLE, GM,
COOK, AL,
Vandesompele, Jo,
Boonefaes, Tom,
Rottiers, Pieter,
...
Neuroblastoma cells with overexpressed MYCN retain their capacity to undergo neuronal differentiation (2004)
EDSJO, A,
NILSSON, H,
Vandesompele, Jo,
KARLSSON, J,
Pattyn, Filip,
CULP, LA,
...
Loss-of-function mutations in LEMD3 result in osteopoikilosis, Buschke-Ollendorff syndrome and melorheostosis (2004)
Hellemans, Jan,
PREOBRAZHENSKA, O,
Willaert, Andy,
DEBEER, P,
Verdonk, Peter,
COSTA, T,
...
DUP25 remains unconfirmed (2004)
Vermeulen, Stefan,
Menten, Björn,
De Bie, Sylvia,
Coucke, Paul,
Malfait, Fransiska,
De Backer, Julie,
...
Claes Lundsteen - in memoriam (2004)
GRAHAM, J,
BLENNOW, E,
BOAVIDA, MG,
CARTER, N,
CREMER, C,
CREMER, T,
...
Proneural and proneuroendocrine transcription factor expression in cutaneous mechanoreceptor (Merkel) cells and Merkel cell carcinoma (vol 101, pg 103, 2002) (2004)
LEONARD, JH,
COOK, AL,
Van Gele, Mireille,
BOYLE, GM,
INGLIS, KJ,
Speleman, Franki,
...
Molecular analysis of the putative tumour-suppressor gene EXTL1 in neuroblastoma patients and cell lines (2004)
MATHYSEN, D,
Van Roy, Nadine,
VAN HUL, W,
Laureys, Genevieve,
AMBROS, P,
Speleman, Franki,
...
No evidence for involvement of SDHD in neuroblastoma pathogenesis (2004)
De Preter, Katleen,
Vandesompele, Jo,
Hoebeeck, Jasmien,
VANDENBROECKE, C,
Smet, Joél,
NUYTS, ANN,
...
Recommendations for the cytogenetic management of myelodysplastic syndromes proposed by the Groupe Francais de Cytogenetique Hematologique (GFCH) (2004)
BASTARD, C,
LUCQUET, I,
MOZZICONACCI, MJ,
Poppe, Bruce,
RAYNAUD, S,
Speleman, Franki
Recommendations for the cytogenetic management of acute myeloblastic leukemia (AML) proposed by the Groupe Francais de Cytogenetique Hematologique (GFCH) (2004)
BASTARD, C,
BARANGER, L,
BILHOU-NABERA, C,
CHARRIN, C,
DASTUGUE, N,
ECLACHE, V,
...
Recommendations for the cytogenetic management of adult and chidhoodacute lymphoblastic leukemia (ALL) proposed by the Groupe Francais de Cytogenetique Hematologique (GFCH) (2004)
BARANGER, L,
BARI, C,
CHARRIN, C,
CORNILLET-LEFEBVRE, P,
DASTUGUE, N,
LAFAGE-POCHITALOFF, M,
...
ID2 expression in neuroblastoma does not correlate to MYCN levels and lacks prognostic value (2003)
Vandesompele, Jo,
EDSJO, A,
De Preter, Katleen,
AXELSON, H,
Speleman, Franki,
PAHLMAN, S
Application of laser capture microdissection in genetic analysis of neuroblastoma and neuroblastoma precursor cells (2003)
De Preter, Katleen,
Vandesompele, Jo,
HEIMANN, P,
KOCKX, MM,
VAN GELE, M,
Hoebeeck, Jasmien,
...
Loss-of-function mutations in FGFR1 cause autosomal dominant Kallmann syndrome (2003)
DODE, C,
LEVILLIERS, J,
DUPONT, JM,
De Paepe, Anne,
LE DU, N,
SOUSSI-YANICOSTAS, N,
...
Evidence for involvement of a tumor suppressor gene on 1p in malignant peripheral nerve sheath tumors (2003)
Van Roy, Nadine,
VAN GELE, M,
Vandesompele, Jo,
Messiaen, Ludwine,
Van Belle, Simon,
SCIOT, R,
...
Quality assessment of genetic markers used for therapy stratification (2003)
AMBROS, IM,
BENARD, J,
BOAVIDA, M,
BOWN, N,
CARON, H,
COMBARET, V,
...
Evidence for involvement of a tumor suppressor gene on 1p in malignant peripheral nerve sheath tumors (2003)
Van Roy, Nadine,
VAN GELE, M,
Vandesompele, Jo,
Messiaen, Ludwine,
Van Belle, Simon,
MORTELE, K,
...
Gene expression profiling reveals two distinct subtypes of Merkel cell carcinoma. The Merkel cell (2003)
VAN GELE, M,
BOYLE, G,
COOK, A,
Boonefaes, Tom,
ROTTIERS, P,
Van Roy, Nadine,
...
Expression profiling reveals involvement of the GABA(A) receptor subunit delta in the fragile X syndrome (2003)
GANTOIS, I,
Vandesompele, Jo,
Speleman, Franki,
D'HOOGE, R,
SEVERIJNEN, L,
WILLEMSEN, R,
...
Quantitative Real Time Polymerase Chain Reaction for measurement of human Interleukin – 5 receptor alpha spliced isoforms mRNA (2003)
Perez Novo, Claudina,
Vandesompele, Jo,
Holtappels, Gabriële,
Speleman, Franki,
Gevaert, Philippe,
Van Cauwenberge, Paul,
...
t(5;14)/HOX11L2-positive T-cell acute lymphoblastic leukemia. A collaborative study of the Groupe Francais de Cytogenetique Hematologique (GFCH) (2003)
BERGER, R,
DASTUGUE, N,
BUSSON, M,
PEROT, C,
BALLERINI, P,
...
ALK activation by the CLTC-ALK fusion is a recurrent event in large B-cell lymphoma (2003)
DE PAEPE, P,
BAENS, M,
VAN KRIEKEN, H,
Verhasselt, Bruno,
STUL, M,
SIMONS, ANN,
...
Gene expression profiling reveals two distinct subtypes of Merkel cell carcinoma (2003)
VAN GELE, M,
BOYLE, G,
COOK, AL,
Boonefaes, Tom,
Rottiers, Pieter,
Van Roy, Nadine,
...
Quantification of MYCN, DDX1, and NAG gene copy number in neuroblastoma using a real-time quantitative PCR assay. (2002)
De Preter, Katleen,
Speleman, Franki,
COMBARET, V,
LUNEC, J,
Laureys, Genevieve,
EUSSEN, B,
...
Proneural and proneuroendocrine transcription factor expression in cutaneous mechanoreceptor (Merkel) cells and Merkel cell carcinoma. (2002)
LEONARD, JH,
COOK, AL,
Van Gele, Mireille,
BOYLE, GM,
INGLIS, KJ,
Speleman, Franki,
...
Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes. (2002)
Vandesompele, Jo,
De Preter, Katleen,
Pattyn, Filip,
Poppe, Bruce,
Van Roy, Nadine,
De Paepe, Anne,
...
Molecular cytogenetic analysis of 10;11 rearrangements in acute myeloid leukemia. (2002)
Van Limbergen, Heidi,
Poppe, Bruce,
JANSSENS, A,
DE BOCK, R,
De Paepe, Anne,
NOENS, L,
...
Kallmann syndrome in a patient with congenital spherocytosis and an interstitial 8p11.2 deletion. (2002)
Vermeulen, Stefan,
Messiaen, Ludwine,
SCHEIR, P,
De Bie, Sylvia,
Speleman, Franki,
De Paepe, Anne
Meerkleuren fluorescentie in situ hybridisatie : methodologie en toepassingen in diagnostiek en onderzoek. (2002)
Van Limbergen, Heidi,
Poppe, Bruce,
Vermeulen, Stefan,
Van Roy, Nadine,
De Paepe, Anne,
Speleman, Franki
Localization of the 17q breakpoint of a constitutional 1;17 translocation in a patient with neuroblastoma within a 25-kb segment located between the ACCN1 and TLK2 genes and near the distal breakpoints of two microdeletions in neurofibromatosis type I patients. (2002)
Van Roy, Nadine,
Vandesompele, Jo,
Berx, Geert,
STAES, K,
Van Gele, Mireille,
De Smet, Els,
...
Combined karyotyping, CGH and M-fish analysis allows detailed characterization of unidentified chromosomal rearrangements in Merkel cell carcinoma. (2002)
Van Gele, Mireille,
LEONARD, JH,
Van Roy, Nadine,
Van Limbergen, Heidi,
Van Belle, Simon,
Cocquyt, Veronique,
...
Identification of cytogenetic subclasses and recurring chromosomal aberrations in AML and MDS with complex karyotypes using M-FISH. (2002)
Van Limbergen, Heidi,
Poppe, Bruce,
MICHAUX, L,
HERENS, C,
BROWN, J,
Noens, Lucien,
...
Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes (2002)
De Paepe, Anne,
De Preter, Katleen,
Pattyn, Filip,
Poppe, Bruce,
Speleman, Franki,
Van Roy, Nadine,
...
HOX11L2 expression linked to t(5;14)(q35;q32) is not associated with poor prognosis in childhood T-ALL treated in EORTC trials 58 881 and 58 951 (2002)
CAVÉ, H,
SUCIU, S,
PREUDHOMME, C,
Poppe, Bruce,
ROBERT, A,
UYTTEBROEK, A,
...
Detailed characterization of 12 supernumerary ring chromosomes using micro-FISH and search for uniparental disomy. (2001)
ANDERLID, BM,
SAHLEN, S,
SCHOUMANS, J,
HOLMBERG, E,
AHSGREN, I,
Mortier, Geert,
...
Comparative genomic hybridization (CGH) analysis of stage 4 neuroblastoma reveals high frequency of 11Q deletion in tumors lacking MYCN amplification. (2001)
PLANTAZ, D,
Vandesompele, Jo,
Van Roy, Nadine,
LASTOWSKA, M,
BOWN, N,
COMBARET, V,
...
Chromosomal aberrations in Bloom syndrome patients with myeloid malignancies. (2001)
Poppe, Bruce,
Van Limbergen, Heidi,
Van Roy, Nadine,
VANDECRUYS, E,
De Paepe, Anne,
Benoit, Yves,
...
Tumor formation and inactivation of RIZ1, an Rb-binding member of a nuclear protein-methyltransferase superfamily. (2001)
STEELE-PERKINS, G,
FANG, W,
YANG, XH,
Van Gele, Mireille,
CARLING, T,
GU, J,
...
Multicentre analysis of patterns of DNA gains and losses in 204 neuroblastoma tumors: How many genetic subgroups are there? (2001)
Vandesompele, Jo,
Speleman, Franki,
Van Roy, Nadine,
Laureys, Genevieve,
BRINKSCHMIDT, C,
CHRISTIANSEN, H,
...
Short communication : Frequent allelic loss at 10q23 but low incidence of PTEN mutations in Merkel cell carcinoma. (2001)
Van Gele, Mireille,
LEONARD, JH,
Van Roy, Nadine,
COOK, AL,
De Paepe, Anne,
Speleman, Franki
Molecular cytogenetic and clinical findings in ETV6/ABL1-positive leukemia. (2001)
Van Limbergen, Heidi,
BEVERLOO, HB,
VAN DRUNEN, E,
Janssens, Ann,
HAHLEN, K,
Poppe, Bruce,
...
Combined M-FISH and CGH analysis allows comprehensive description of genetic alterations in neuroblastoma cell lines. (2001)
Van Roy, Nadine,
Van Limbergen, Heidi,
Vandesompele, Jo,
Van Gele, Mireille,
Poppe, Bruce,
SALWEN, H,
...
Molecular cytogenetic definition of 17q translocation breakpoints in neuroblastoma. (2001)
LASTOWSKA, M,
Van Roy, Nadine,
BOWN, N,
Speleman, Franki,
ROBERTS, P,
LUNEC, J,
...
Frequent allelic loss at 10q23 but low incidence of PTEN mutations in Merkel cell carcinoma. (2001)
VAN GELE, M,
LEONARD, JH,
Van Roy, Nadine,
COOK, AL,
De Paepe, Anne,
Speleman, Franki
Molecular characterization of a t(2;3)(p23;q26): A recurrent translocation involving the EVI1 gene (2001)
Poppe, Bruce,
Yigit, Nurten,
MARYNEN, P,
HAGEMEIJER, A,
VAN LIMBERGEN, H,
DE SMET, B,
...
Deletion of chromosome 11q is the most frequent deletion detected by CGH in metastatic neuroblastoma lacking MYCN amplification (2001)
PLANTAZ, D,
VANDESOMPELE, J,
Van Roy, Nadine,
BROWN, N,
NICHOLSON, J,
LASTOWSKA, M,
...
Mutation analysis of P73 and TP53 in Merkel cell carcinoma. (2000)
Van Gele, Mireille,
KAGHAD, M,
LEONARD, JH,
Van Roy, Nadine,
Naeyaert, Jean,
Geerts, Maria,
...
Structure and mutation analysis of the gene encoding DNA fragmentation factor 40 (caspase-activated nuclease), a candidate neuroblastoma tumour suppressor gene. (2000)
JUDSON, H,
Van Roy, Nadine,
STRAIN, L,
Vandesompele, Jo,
Van Gele, Mireille,
Speleman, Franki,
...
Exhaustive mutation analysis of the NF1 gene allows identification of 95% of mutations and reveals a high frequency of unusual splicing defects. (2000)
Messiaen, Ludwine,
CALLENS, T,
Mortier, Geert,
Beysen, Diane,
Vandenbroucke, Ina,
Van Roy, Nadine,
...
Subtelomeric familial translocation t(2;7)(q37;q35) leading to partial trisomy 7q35 -> qter: Molecular cytogenetic analysis and clinical phenotype in two generations. (2000)
Speleman, Franki,
CALLENS, B,
Logghe, Karl,
Van Roy, Nadine,
JAUCH, A,
VERSCHRAEGEN-SPAE, MR,
...
An integrated 5-Mb physical, genetic, and radiation hybrid map of a 1p36.1 region implicated in neuroblastoma pathogenesis. (2000)
SPIEKER, N,
BEITSMA, M,
VAN SLUIS, P,
ROOBEEK, I,
DEN DUNNEN, JT,
Speleman, Franki,
...
Chromosome 2 short arm translocations revealed by M-FISH analysis of neuroblastoma cell lines. (2000)
Van Roy, Nadine,
Van Limbergen, Heidi,
Vandesompele, Jo,
Van Gele, Mireille,
Poppe, Bruce,
Laureys, Genevieve,
...
Deletion mapping on the short arm of chromosome 1 in Merkel cell carcinoma. (2000)
LEONARD, JH,
COOK, AL,
NANCARROW, D,
HAYWARD, N,
VAN GELE, M,
Van Roy, Nadine,
...
Technetium-99m sestamibi imaging in paediatric neuroblastoma and ganglioneuroma and its relation to P-glycoprotein. (1999)
De Moerloose, Barbara,
Dhooge, Catharina,
Philippe, Jan,
Speleman, Franki,
Benoit, Yves,
...
Mapping of novel regions of DNA gain and loss by comparative genomic hybridization in esophageal carcinoma in the black and colored populations of South Africa. (1999)
DU PLESSIS, L,
DIETZSCH, E,
Van Gele, Mireille,
Van Roy, Nadine,
VAN HELDEN, P,
PARKER, MI,
...
Refined physical mapping and genomic structure of the EXTL1 gene. (1999)
WUYTS, W,
SPIEKER, N,
Van Roy, Nadine,
DE BOULLE, K,
De Paepe, Anne,
WILLEMS, PJ,
...
The alpha E-catenin gene (CTNNA1) acts as an invasion-suppressor gene in human colon cancer cells. (1999)
VERMEULEN, SJ,
Nollet, Friedel,
TEUGELS, E,
VENNEKENS, KM,
MALFAIT, F,
Philippe, Jan,
...
hMSH6 deficiency and inactivation of the alpha E-catenin invasion-suppressor gene in HCT-8 colon cancer cells. (1999)
VERMEULEN, SJ,
Debruyne, Philip,
MARRA, G,
Speleman, Franki,
BOUKAMP, P,
JIRICNY, J,
...
Delineation of two distinct 6p deletion syndromes. (1999)
DAVIES, AF,
MIRZA, G,
SEKHON, G,
TURNPENNY, P,
LEROY, F,
Speleman, Franki,
...
Gain of chromosome arm 17q and adverse outcome in patients with neuroblastoma. (1999)
BOWN, N,
COTTERILL, S,
LASTOWSKA, M,
O'NEILL, S,
PEARSON, ADJ,
PLANTAZ, D,
...
Closing in an the BPES gene on 3q23: Mapping of a de nova reciprocal translocation t(3;4)(q23;p15.2) breakpoint within a 45-kb cosmid and mapping of three candidate genes, RBP1, RBP2, and beta '-COP, distal to the breakpoint (1999)
De Baere, Elfride,
Van Roy, Nadine,
Speleman, Franki,
FUKUSHIMA, Y,
De Paepe, Anne,
Messiaen, Ludwine
Neuroblastoma: from molecular cytogenetics to gene expression profiling (1999)
Vandesompele, Jo,
Van Roy, Nadine,
Berx, Geert,
PLANTAZ, D,
De Paepe, Anne,
Laureys, Genevieve,
...
Cytogenetic findings in bloom syndrome patients with myeloid malignancies (1999)
Poppe, Bruce,
Benoit, Yves,
VAN LIMBERGEN, H,
Van Roy, Nadine,
VANDECRUYS, ELS,
JAUCH, A,
...
Unusual chromosome 16 rearrangement with absence of classical CBFB/MYH11 fusion transcripts (1999)
VAN LIMBERGEN, H,
VAN DER REIJDEN, BA,
Poppe, Bruce,
Van Roy, Nadine,
DAUWERSE, H,
De Paepe, Anne,
...
99mTc-MIBI imaging in paediatric neuroblastoma and ganglioneuroma and its relation to P-glycoprotein (1999)
DE MOERLOOSE, B,
Dhooge, Catharina,
PHILIPPE, J,
Speleman, Franki,
Benoit, Yves,
...
Chromosome 7 short arm deletions and disease progression in CML (1999)
Poppe, Bruce,
VAN LIMBERGEN, H,
JANSSENS, ANN,
Van Roy, Nadine,
De Moerloose, Barbara,
PHILLIPE, J,
...
A single step real-time quantitative RT-PCR reaction for detection of the BCR/ABL fusion product (1999)
VAN LIMBEREN, H,
Poppe, Bruce,
De Paepe, Anne,
Offner, Fritz,
MENSINK, E,
...
Identification of a novel CBFB/MYH11 fusion in a patient with AML-M1 and a t(16;16)(p13;q22) (1999)
VAN LIMBERGEN, H,
Poppe, Bruce,
Offner, Fritz,
Van Roy, Nadine,
DAUWERSE, H,
...
Did the four human cancer cell lines DLD-1, HCT-15, HCT-8, and HRT-18 originate from one and the same patient? (1998)
VERMEULEN, SJ,
CHEN, TR,
Speleman, Franki,
NOLLET, F,
Van Roy, Frans,
MAREEL, MARCUS
Ossified retroperitoneal malignant Schwannoma with spinal leptomeningeal metastases. (1998)
MORTELE, K,
Lemmerling, Marc,
Defreyne, Luc,
Speleman, Franki,
De Potter, Christian,
Van Belle, Simon,
...
Identification of a third EXT-like gene (EXTL3) belonging to the EXT gene family. (1998)
VAN HUL, W,
WUYTS, W,
HENDRICKX, J,
Speleman, Franki,
WAUTERS, J,
DE BOULLE, K,
...
Cytogenetic and molecular analysis of cellular atypical mesoblastic nephroma. (1998)
Speleman, Franki,
Dhooge, Catharina,
OOSTERHUIS, W,
REDEKER, B,
De Potter, Christian,
...
FISH identifies inv(16)(p13q22) masked by translocations in three cases of acute myeloid leukemia. (1998)
DIERLAMM, J,
STUL, M,
VRANCKX, H,
MICHAUX, L,
WEGHUIS, DEMO,
Speleman, Franki,
...
Molecular analysis of lp36 breakpoints in two Merkel cell carcinomas. (1998)
Van Gele, Mireille,
Van Roy, Nadine,
RONAN, SG,
Messiaen, Ludwine,
Vandesompele, Jo,
Geerts, Maria,
...
Molecular cytogenetic delineation of 17q translocation breakpoints in neuroblastoma cell lines. (1998)
LASTOWSKA, M,
Van Roy, Nadine,
BROWN, N,
Speleman, Franki,
LUNEC, J,
STRACHAN, T,
...
Genetic heterogeneity of neuroblastoma studied by comparative genomic hybridization. (1998)
Vandesompele, Jo,
Van Roy, Nadine,
Van Gele, Mireille,
Laureys, Genevieve,
AMBROS, P,
HEIMANN, P,
...
Noonan-like phenotype in monozygotic twins with a duplication-deficiency of the long arm of chromosome 18 resulting from a maternal paracentric inversion. (1998)
COURTENS, W,
GROSSMAN, D,
Van Roy, Nadine,
Messiaen, Ludwine,
VAMOS, E,
TOPPET, V,
...
Department of Radiology, University Hospital Gent, Belgium (1998)
MORTELE, K,
Lemmerling, Marc,
Defreyne, Luc,
Speleman, Franki,
DE POTTER, C,
Van Belle, Simon,
...
Did the four human cancer cell lines DLD-1, HCT-15, HCT-8, and HRT-18 originate from one and the same patient ? (1998)
VERMEULEN, SJ,
CHEN, TR,
Speleman, Franki,
Nollet, Friedel,
Van Roy, Frans,
MAREEL, MM
Assignment of the cellular retinol-binding protein 2 gene (RBP2) to human chromosome band 3q23 by in situ hybridization (1998)
De Baere, Elfride,
Speleman, Franki,
Van Roy, Nadine,
MORTIER, K,
De Paepe, Anne,
Messiaen, Ludwine
Mutation of alpha-catenin results in invasiveness of human HCT-8 colon cancer cells. (1997)
VERMEULEN, SJ,
NOLLET, F,
TEUGELS, E,
Philippe, Jan,
Speleman, Franki,
Van Roy, Frans,
...
Analysis of 1;17 translocation breakpoints in neuroblastoma: Implications for mapping of neuroblastoma genes. (1997)
Van Roy, Nadine,
Laureys, Genevieve,
Van Gele, Mireille,
OPDENAKKER, G,
MIURA, R,
...
Sensitive and reliable detection of genomic imbalances in human neuroblastomas using comparative genomic hybridisation analysis. (1997)
Van Gele, Mireille,
Van Roy, Nadine,
JAUCH, A,
Laureys, Genevieve,
Benoit, Yves,
Schelfhout, Vera,
...
Identification and characterization of a novel member of the EXT gene family, EXTL2. (1997)
WUYTS, W,
VAN HUL, W,
HENDRICKX, J,
Speleman, Franki,
WAUTERS, J,
DE BOULLE, K,
...
Amplification units and translocation at chromosome 17q and c-erbB-2 overexpression in the pathogenesis of breast cancer. (1997)
Coene, Elisabeth,
Schelfhout, Vera,
WINKLER, RA,
SCHELFHOUT, AM,
Van Roy, Nadine,
GROOTECLAES, M,
...
Malignant melanoma of the soft parts (clear-cell sarcoma): Confirmation of EWS and ATF-1 gene fusion caused by a t(12;22) translocation. (1997)
Speleman, Franki,
DELATTRE, O,
PETER, M,
HAUBEN, E,
Van Roy, Nadine,
VANMARCK, E
Monosomy 22 in a mixed germ cell sex cord stromal tumor of the ovary. (1997)
Speleman, Franki,
DERMAUT, B,
DEPOTTER, CR,
VANGELE, M,
Van Roy, Nadine,
DEPAEPE, A,
...
Comparative genomic hybridization analysis of human neuroblastomas: Detection of distal 1p deletions and further molecular genetic characterization of neuroblastoma cell lines. (1997)
Van Roy, Nadine,
JAUCH, A,
VANGELE, M,
Laureys, Genevieve,
VERSTEEG, R,
DEPAEPE, A,
...
Interstitial deletion 2q33.3-q34 in a boy with a phenotype resembling the Seckel syndrome. (1997)
COURTENS, W,
Speleman, Franki,
Messiaen, Ludwine,
BORMANS, J,
Van Roy, Nadine,
VAMOS, E
A constitutional balanced 1;17 neuroblastoma translocation (1997)
CHAN, A,
Laureys, Genevieve,
Van Roy, Nadine,
WESTERVELD, A,
Speleman, Franki,
...
Localization by fluorescence in situ hybridization of the human functional beta-glucuronidase gene (GUSB) to 7q11.21->q11.22 and two pseudogenes to 5p13 and 5q13. (1996)
Speleman, Franki,
VERVOORT, R,
Van Roy, Nadine,
LIEBAERS, I,
SLY, WS,
LISSENS, W
A human modifier of methylation for class I HLA genes (MEMO-1) maps to chromosomal bands 1p35-36.1. (1996)
CHENG, NC,
CHAN, AJK,
BEITSMA, MM,
Speleman, Franki,
WESTERVELD, A,
VERSTEEG, R
Refined genetic and physical mapping of BPES type II. (1996)
Messiaen, Ludwine,
LEROY, BP,
DEBIE, S,
DEPAUW, K,
Van Roy, Nadine,
Speleman, Franki,
...
Mosaic tetrasomy 15q25->qter in a newborn infant with multiple anomalies. (1996)
VANDENENDEN, A,
VERSCHRAEGEN-SPAE, MR,
Van Roy, Nadine,
DECALUWE, W,
DEPRAETER, C,
Speleman, Franki
Acute lymphoblastic leukemia as part of the retinoblastoma inherited cancer syndrome (1996)
VAN DROOGENBROECK, J,
Noens, Lucien,
JANSSENS, A,
Offner, Fritz,
Van Hove, Werner,
Speleman, Franki
Chromosomal region 1p35-36 encodes for several neuroblastoma suppressor loci (1996)
VERSTEEG, R,
CARON, H,
VANDERDRIFT, P,
Speleman, Franki,
Laureys, Genevieve,
Van Roy, Nadine,
...
Deletion mapping in neuroblastoma cell-lines suggests 2 distinct tumor-suppressor genes in the lp35-36 region, only one of which is associated with N-myc amplification. (1995)
CHENG, NC,
Van Roy, Nadine,
CHAN, A,
BEITSMA, M,
WESTERVELD, A,
Speleman, Franki,
...
CONSTITUTIONAL TRANSLOCATION T(1-17)(P36.31-P36.13-Q11.2Q12.1) IN A NEUROBLASTOMA PATIENT. ESTABLISHMENT OF SOMATIC-CELL HYBRIDS AND IDENTIFICATION OF PND/A12M2 ON CHROMOSOME-1 AND NF1/SCYA7 ON CHROMOSOME-17 AS BREAKPOINT FLANKING SINGLE-COPY MARKERS. (1995)
Laureys, Genevieve,
Speleman, Franki,
VERSTEEG, R,
VANDERDRIFT, P,
CHAN, A,
Leroy, Juliaan,
...
Evidence for 2 tumour-suppressor loci on chromosomal bands-lp35-36 involved in neuroblastoma - one probably imprinted, another associated with N-myc amplification. (1995)
CARON, H,
PETER, M,
VANSLUIS, P,
Speleman, Franki,
DEKRAKER, J,
Laureys, Genevieve,
...
Assignment of the human beta-catenin gene (CTNNB1) to 3p22->p21.3 by fluorescence in situ hybridization. (1995)
VANHENGEL, J,
NOLLET, F,
Berx, Geert,
Van Roy, Nadine,
Speleman, Franki,
Van Roy, Frans
Characterization of the chromosome breakpoints in a patient with a constitutional translocation T(1-17)(P36.31-P36.13-Q11.2-Q12) and neuroblastoma. (1995)
Laureys, Genevieve,
VERSTEEG, R,
Speleman, Franki,
VANDERDRIFT, P,
FRANCKE, U,
OPDENAKKER, G,
...
Molecular cytogenetic analysis of 1-17 translocations in neuroblastoma. (1995)
Van Roy, Nadine,
CHENG, NC,
Laureys, Genevieve,
OPDENAKKER, G,
VERSTEEG, R,
Speleman, Franki
1P36 - EVERY SUBBAND A SUPPRESSOR. (1995)
VERSTEEG, R,
CARON, H,
CHENG, NC,
VANDERDRIFT, P,
SLATER, R,
WESTERVELD, A,
...
Identification of 2 distinct chromosome-12-derived amplification units in neuroblastoma cell-line NGP. (1995)
Van Roy, Nadine,
FORUS, A,
MYKLEBOST, O,
CHENG, NC,
VERSTEEG, R,
Speleman, Franki
BALANCED TRANSLOCATION IN A NEUROBLASTOMA PATIENT DISRUPTS A CLUSTER OF SMALL NUCLEAR-RNA UI AND TRANSFER-RNA GENES IN CHROMOSOMAL BAND 1P36. (1995)
VANDERDRIFT, P,
CHAN, A,
Laureys, Genevieve,
Van Roy, Nadine,
SICKMANN, G,
DENDUNNEN, J,
...
THE GENE FOR HUMAN GAP JUNCTION PROTEIN CONNEXIN37 (GJA4) MAPS TO CHROMOSOME 1P35.1, IN THE VICINITY OF D1S195. (1995)
VANCAMP, G,
Coucke, Paul,
Speleman, Franki,
Van Roy, Nadine,
BEYER, EC,
OOSTRA, BA,
...
Localization of the gene (RSN) coding for restin, a marker for Reed-Sternberg cells in Hodgkin's disease, to human chromosome band 12q24.3 and YAC cloning of the locus. (1994)
HILLIKER, C,
DELABIE, J,
Speleman, Franki,
BILBE, G,
BRUGGEN, J,
VANLEUVEN, F,
...
I-17 TRANSLOCATIONS AND OTHER CHROMOSOME-17 REARRANGEMENTS IN HUMAN PRIMARY NEUROBLASTOMA TUMORS AND CELL-LINES. (1994)
Van Roy, Nadine,
Laureys, Genevieve,
CHENG, NC,
WILLEM, P,
OPDENAKKER, G,
VERSTEEG, R,
...
The human MCP-3 gene (SCYA7) : cloning, sequence analysis, and assignment to the C-C chemokine gene cluster on chromosome 17ql 1.2-ql2. (1994)
OPDENAKKER, G,
FITEN, P,
NYS, G,
FROYEN, G,
Van Roy, Nadine,
Speleman, Franki,
...
Proximal deletion of chromosome-21 confirmed by in-situ hybridization and molecular studies. (1994)
COURTENS, W,
PETERSEN, MB,
NOEL, JC,
FLAMENT-DURAND, J,
VANREGEMORTER, N,
DELNESTE, D,
...
6 CASES OF 7P DELETION - CLINICAL, CYTOGENETIC, AND MOLECULAR STUDIES. (1994)
CHOTAI, KA,
BRUETON, LA,
VANHERWERDEN, L,
GARRETT, C,
HINKEL, GK,
SCHINZEL, A,
...
Recurrent I,17 translocations in human neuroblastoma reveal non-homologous recombination during the S/G2 phase as a novel mechanism for loss of heterozygosity. (1994)
CARON, H,
VANSLUIS, P,
Van Roy, Nadine,
DEKRAKER, J,
Speleman, Franki,
VOUTE, PA,
...
CHROMOSOME-ABERRATIONS IN FIBROUS DYSPLASIA. (1994)
DALCIN, P,
SCIOT, R,
Speleman, Franki,
SAMSON, I,
Laureys, Genevieve,
DEPOTTER, C,
...
Chromosome abberations in fibrous dysplasia (1994)
DALCIN, P,
SCIOT, R,
Speleman, Franki,
SAMSON, I,
LAUREYS, G,
DE POTTER, C,
...
A MULTIMEGABASE CLUSTER OF SNRNA AND TRANSFER-RNA GENES ON CHROMOSOME 1P36 HARBORS AN ADENOVIRUS SV40 HYBRID VIRUS INTEGRATION SITE (1994)
VANDERDRIFT, P,
CHAN, A,
Van Roy, Nadine,
Laureys, Genevieve,
WESTERVELD, A,
Speleman, Franki,
...
HIGH-RESOLUTION FLUORESCENCE MAPPING OF 43 DNA MARKERS TO CHROMOSOME BAND-1P36 (1994)
Van Roy, Nadine,
VANDERDRIFT, P,
Laureys, Genevieve,
OPDENAKKER, G,
VERSTEEG, R,
Speleman, Franki
HIGH-RESOLUTION CHROMOSOMAL LOCALIZATION OF THE HUMAN CALCITONIN CGRP/IAPP GENE FAMILY MEMBERS. (1993)
HOOVERS, JMN,
REDEKER, E,
Speleman, Franki,
HOPPENER, JWM,
BHOLA, S,
BLIEK, J,
...
EWS AND ATF-1 GENE FUSION INDUCED BY T(12-22) TRANSLOCATION IN MALIGNANT-MELANOMA OF SOFT PARTS. (1993)
ZUCMAN, J,
DELATTRE, O,
DESMAZE, C,
EPSTEIN, AL,
STENMAN, G,
Speleman, Franki,
...
MOLECULAR CYTOGENETIC ANALYSIS OF A FAMILIAL PERICENTRIC-INVERSION OF CHROMOSOME-12. (1993)
Speleman, Franki,
Van Roy, Nadine,
DEVOS, E,
HILLIKER, C,
SUIJKERBUIJK, RFS,
Leroy, Juliaan
Molecular cytogenetic analysis of a complex t(10;20;ll) translocation in Ewing's Sarcoma. (1992)
Speleman, Franki,
Van Roy, Nadine,
WIEGANT, J,
DIERICK, AM,
Uyttendaele, Dirk,
Leroy, Juliaan
Detection of subtle reciprocal translocations by fluorescence in situ hibridization. (1992)
Speleman, Franki,
Van Roy, Nadine,
WIEGANT, J,
VERSCHRAEGEN-SPAE, MR,
Benoit, Yves,
GOVAERT, P,
...
Molecular cytogenetic analysis of XX males using Y-specific DNA-sequences, including SRY. (1992)
VANDERAUWERA, B,
Van Roy, Nadine,
DEPAEPE, A,
HAWKINS, JR,
LIEBAERS, I,
CASTEDO, S,
...
RECIPROCAL TRANSLOCATION BETWEEN THE PROXIMAL REGIONS OF THE LONG ARMS OF CHROMOSOME-13 AND CHROMOSOME-15 RESULTING IN UNBALANCED OFFSPRING - CHARACTERIZATION BY FLUORESCENCE INSITU HYBRIDIZATION AND DNA ANALYSIS. (1992)
MANGELSCHOTS, K,
VANROY, B,
Speleman, Franki,
Van Roy, Nadine,
GHEUENS, J,
BEUTEN, J,
...
I(12P) IN A NEAR-DIPLOID MATURE OVARIAN TERATOMA. (1992)
Speleman, Franki,
Laureys, Genevieve,
Benoit, Yves,
Cuvelier, Claude,
SUIJKERBUIJK, R,
DEJONG, B
PUTATIVE MONOSOMY-21 IN 2 PATIENTS - CLINICAL FINDINGS AND INVESTIGATION USING FLUORESCENCE INSITU HYBRIDIZATION. (1992)
VILJOEN, DL,
Speleman, Franki,
SMART, R,
Van Roy, Nadine,
DUTOIT, J,
Leroy, Juliaan
Molecular cytogenetic analysis of a complex t (10;22;ll). Translocation in Ewing's sarcoma (1992)
Speleman, Franki,
Van Roy, Nadine,
WIEGANT, J,
DIERICK, AM,
Uyttendaele, Dirk,
LEROY, JG
EXTRA TRANSLOCATION +DER(1Q9P) IS A PROGNOSTIC INDICATOR IN MYELOPROLIFERATIVE DISORDERS. (1991)
REGECAMBRIN, G,
Speleman, Franki,
KERIM, S,
SCARAVAGLIO, P,
CAROZZI, F,
DALCIN, P,
...
Pallister-Killian Syndrome : characterization of the isochromosome 12p by fluorescent in situ hybridization (1991)
Speleman, Franki,
Leroy, Juliaan,
Van Roy, Nadine,
De Paepe, Anne,
SUUKERBUUK, R,
BRUNNER, J,
...
ANALYSIS OF WHOLE-ARM TRANSLOCATIONS IN MALIGNANT BLOOD-CELLS BY NONISOTOPIC IN SITU HYBRIDIZATION (WITH 1 COLOR PLATE) (1991)
Speleman, Franki,
MANGELSCHOTS, K,
VERCRUYSSEN, M,
DALCIN, P,
AVENTIN, A,
Offner, Fritz,
...
De ovariële functie bij het Turner syndroom. T. Geneesk., 1991, 47, pp. 993-996.
Depypere, Herman,
DE PAEPE, A,
VERSCHRAEGEN-SPAE, MR,
Speleman, Franki,
Dhont, Marc,
Vandekerckhove, Dirk
Platelet-derived growth factor A chain : confirmation of localization of PDGFA to chromosome 7p22 and description of an unusual minisatellite. Genomics, 1992, 13, pp. 257-263.
BONTHRON, D,
COLLINS, T,
GRZESCHIK, KH,
Van Roy, Nadine,
Speleman, Franki
Reciprocal translocation between the proximal regions of the long arms of chromosomes 13 and 15 resulting in unbalanced offspring : characterization by fluorescence in situ hybridization and DNA analysis. Hum. Genet. 1992, 89, pp. 4O7-413.
MANGELSCHOTS, K,
VAN ROY, B,
Speleman, Franki,
VAN ROY, J,
GHEUENS, N,
BEUTEN, J,
...
Extra translocation t(lq9p) is a prognostic indicator in myeloproliferative disorders. Leukemia 1992, 5, pp. 1059-1063.
REGE-CAMBRIN, G,
Speleman, Franki,
KERIM, S,
SCARAVAGLIO, P,
CAROZZI, F,
DAL CIN, P,
...
i(12p) in a near diploid mature ovarian teratoma. Cancer Genet. CytogeneL 1992, 60, p. 216.
Speleman, Franki,
Laureys, Genevieve,
Benoit, Yves,
CUVELIER, C,
SUIJKERBUUK, R,
DE JONG, B
Malignant melanoma of the soft parts : further cytogenetic characterization. Caner Genet. Cytogenet,. 1992, 60, pp. 176-179.
Speleman, Franki,
COLPAERT, C,
GOVAERTS, G,
Leroy, Juliaan,
VAN MARCK, E
Molecular cytogenetic analysis of XX-males using Y-specific DNA sequences, including SRY. Hum. Genet., 1992, 89, 23-28.
Van Roy, Nadine,
HAWKINS, J,
LIEBAERS, I,
De Paepe, Anne,
CASTEDO, S,
...
Familial Turner syndrome. Clin. Genet., 1992, 41: 218-220. D. WILDEMEERSCH, P. DEFOORT, G. MARTENS.
VERSCHRAEGEN-SPAE, MR,
Depypere, Herman,
Speleman, Franki,
Dhont, Marc,
DE PAEPE, A
The Flexigard^ 330 ICC, an ultrasound evaluation. Contraception, 1992, 46: 471-476.
VERSCHRAEGEN-SPAE, MR,
Depypere, Herman,
Speleman, Franki,
Dhont, Marc,
DE PAEPE, A
1;17 translocations and other chromosome 17 rearrangements in human primary neuroblastoma tumor and cell lines. Genes, Chromosomes and Cancer, 1994, 10, 103-114.
Van Roy, Nadine,
Laureys, Genevieve,
CHING CHENG, N,
WILLEM, P,
OPDEN-AKKER, G,
VERSTEEG, R,
...
Blepharophimosis-ptosis-epicanthus inversus syndrome (BPES) : report of a large family. Fifth European Meeting of Dysmorphology, Straatsburg, Frankrijk, 07-10/09/1994. Genetic Counselling 1995, 6, 84A.
LEROY, BP,
VERMEERSCH, H,
Speleman, Franki,
Van Roy, Nadine,
MESSIAEN, LM,
DE PAEPE, AM
Blepharophimosis-Ptosis-Epicanthus inversus Syndrome (BPES) : clinical subtypes and their genotype. Joint European Research Meetings in Ophtalmology and vision. Montpellier, 14-18 oktober 1995. Vision Research, 1995, V 35 suppl.
LEROY, BP,
Messiaen, Ludwine,
Van Roy, Nadine,
Speleman, Franki,
De Paepe, Anne
Ip36: every subband a suppressor ? Eur. J. Cancer, 1995, 31 A, 538-540.
VERSTEEG, R,
CARON, H,
CHENG, NC,
SLATER, R,
WESTERVELD, A,
...
Comparative Genomic hybridisation analysis of human neuroblastomas: detection of distal lp-deletions and further molecular genetic characterisation of neuroblastoma cell lines. Cancer Genet. Cytogenet., 97, 135-142, 1997.
Van Roy, Nadine,
JAUCH, A,
Van Gele, Mireille,
Laureys, Genevieve,
VERSTEEG, R,
De Paepe, Anne,
...
Interstitial telomeric sequences at the junction site of a jumping translocation. Hum. Genet., 1997, 99 : 735-737.
VERMEESCH, JR,
PETIT, P,
Speleman, Franki,
DEVRIENDT, K,
MARYNEN, P
Extended sperm DNA fibres applied to high resolution physical gene mapping. Advances in Reproduction, 1, 1998,187-195.
DINEEN, T,
Speleman, Franki,
Van Roy, Nadine,
NOLAN, A,
HOUGHTON, JA
Molecular diagnostic evaluation of NF1 patients using the combined approach of karyotyping, fluorescent in situ hybridisation, the protein truncation assay and heteroduplex analysis. 7th Annual European Neurofibromatoses Meeting, Paris, December 4-5, 1997. Genetic Counseling, 9, 1998, 294.
Messiaen, Ludwine,
Mortier, Geert,
CALLENS, T,
Van Roy, Nadine,
Speleman, Franki,
De Paepe, Anne
Recurrent chromosomal abnormalities in Merkel cell carcinoma detected by comparative genomic hybridization. Cancer Research, 58, 1998, 1503-1508.
Van Gele, Mireille,
Speleman, Franki,
Vandesompele, Jo,
Van Roy, Nadine,
LEONARD, JH
An Ossified Retroperitoneal Malignant Schwannoma with Spinal Leptomeningeal Métastases. Neuroradiology, 40, 1998, 48-50.
MORTELE, K,
Lemmerling, Marc,
Defreyne, Luc,
Speleman, Franki,
DE POTTER, C,
VAN BELLE, S,
...
The aE-catenin gene (CTNNA1) acts as an invasion-suppressor gene in human colon cancer cells. Oncogene, 18, 1999,905-915.
Vermeulen, Stefan,
NOLLET, F,
TEUGELS, E,
VENNEKENS, KM,
MALFAIT, F,
PHILIPPE, J,
...