Fredrik Åslund

Glutaredoxin function for the carboxyl-terminal domain of the plant-type 5′-adenylylsulfate reductase

Bick, Julie-Ann, Åslund, Fredrik, Chen, Yichang, Leustek, Thomas

5′-Adenylylsulfate (APS) reductase (EC 1.8.99.-) catalyzes the reduction of activated sulfate to sulfite in plants. The evidence presented here shows that a domain of the enzyme is a glutathione...

Efficient folding of proteins with multiple disulfide bonds in the Escherichia coli cytoplasm

Bessette, Paul H., Åslund, Fredrik, Beckwith, Jon, Georgiou, George

Under physiological conditions, the Escherichia coli cytoplasm is maintained in a reduced state that strongly disfavors the formation of stable disulfide bonds in proteins. However, mutants in which...

Regulation of the OxyR transcription factor by hydrogen peroxide and the cellular thiol—disulfide status

Åslund, Fredrik, Zheng, Ming, Beckwith, Jon, Storz, Gisela

The Escherichia coli transcription factor OxyR is activated by the formation of an intramolecular disulfide bond and subsequently is deactivated by enzymatic reduction of the disulfide bond. Here we...

Glutaredoxin function for the carboxyl-terminal domain of the plant-type 5′-adenylylsulfate reductase

Bick, Julie-Ann, Åslund, Fredrik, Chen, Yichang, Leustek, Thomas

5′-Adenylylsulfate (APS) reductase (EC 1.8.99.-) catalyzes the reduction of activated sulfate to sulfite in plants. The evidence presented here shows that a domain of the enzyme is a glutathione...

Efficient folding of proteins with multiple disulfide bonds in the Escherichia coli cytoplasm

Bessette, Paul H., Åslund, Fredrik, Beckwith, Jon, Georgiou, George

Under physiological conditions, the Escherichia coli cytoplasm is maintained in a reduced state that strongly disfavors the formation of stable disulfide bonds in proteins. However, mutants in which...

Regulation of the OxyR transcription factor by hydrogen peroxide and the cellular thiol—disulfide status

Åslund, Fredrik, Zheng, Ming, Beckwith, Jon, Storz, Gisela

The Escherichia coli transcription factor OxyR is activated by the formation of an intramolecular disulfide bond and subsequently is deactivated by enzymatic reduction of the disulfide bond. Here we...