Fredrik Ivars

Identification of Human S100A9 as a Novel Target for Treatment of Autoimmune Disease via Binding to Quinoline-3-Carboxamides (2009)

Per Björk, Anders Björk, Thomas Vogl, Martin Stenström, David Liberg, Anders Olsson, ...

Despite more than 25 years of research, the molecular targets of quinoline-3-carboxamides have been elusive although these compounds are currently in Phase II and III development for treatment of...

Superantigen-Induced Regulatory T Cells in vivo. (2007)

Ivars, Fredrik

Abstract is not available

Dystroglycan is selectively cleaved at the parenchymal basement membrane at sites of leukocyte extravasation in experimental autoimmune encephalomyelitis (2006)

Anderson, Per, Durbeej, Madeleine, Van Rooijen, Nico, Ivars, Fredrik, ...

The endothelial cell monolayer of cerebral vessels and its basement membrane (BM) are ensheathed by the astrocyte endfeet, the leptomeningeal cells, and their associated parenchymal BM, all of which...

Dystroglycan is selectively cleaved at the parenchymal basement membrane at sites of leukocyte extravasation in experimental autoimmune encephalomyelitis. (2006)

Agrawal, Smriti, Anderson, Per, Durbeej, Madeleine, Van Rooijen, Nico, Ivars, Fredrik, Opdenakker, Ghislain, ...

Abstract is not available

Cytotoxic T lymphocyte antigen-4-dependent down-modulation of costimulatory molecules on dendritic cells in CD4+ CD25+ regulatory T-cell-mediated suppression. (2006)

Oderup, Cecilia, Cederbom, Lukas, Makowska, Anna, Cilio, Corrado M, Ivars, Fredrik

Abstract is not available

T cells developing in fetal thymus of T-cell receptor alpha-chain transgenic mice colonize gammadelta T-cell-specific epithelial niches but lack long-term reconstituting potential. (2006)

Leandersson, Karin, Jaensson, Elin, Ivars, Fredrik

Abstract is not available

Costimulation Blockade-Induced Cardiac Allograft Tolerance: Inhibition of T Cell Expansion and Accumulation of Intragraft cD4+Foxp3+ T Cells. (2006)

Oderup, Cecilia, Malm, Helene, Ekberg, Henrik, Qi, Zhongquan, Veress, Béla, Ivars, Fredrik, ...

Abstract is not available

Quinic acid is a biologically active component of the Uncaria tomentosa extract C-Med 100(R). (2005)

Akesson, Christina, Lindgren, Hanna, Pero, Ronald W, Leanderson, Tomas, Ivars, Fredrik

Abstract is not available

Superantigen-Induced Regulatory T Cells Display Different Suppressive Functions in the Presence or Absence of Natural CD4(+)CD25(+) Regulatory T Cells In Vivo. (2003)

Grundström, Susanna, Cederbom, Lukas, Sundstedt, Anette, Scheipers, Peter, Ivars, Fredrik

Abstract is not available

An extract of Uncaria tomentosa inhibiting cell division and NF-kappaB activity without inducing cell death. (2003)

Akesson, Christina, Lindgren, Hanna, Pero, Ronald W, Leanderson, Tomas, Ivars, Fredrik

Abstract is not available

Transforming growth factor-{beta}- and Activin-Smad signaling pathways are activated at distinct maturation stages of the thymopoeisis (2003)

Rosendahl, Alexander, Speletas, Matthaios, Leandersson, Karin, Ivars, Fredrik, Sideras, Paschalis

Members of the transforming growth factor (TGF)‐β family play pivotal roles in the control of differentiation, proliferation and tolerance in peripheral T cells. Recently, they have been...

The pTalpha promoter and enhancer are direct targets for transactivation by E box-binding proteins. (2002)

Petersson, Karin, Ivars, Fredrik, Sigvardsson, Mikael

The pre-Talpha (pTalpha[?]) gene encodes a protein that forms the pre-TCR together with the newly expressed TCR beta chain during a defined stage of early T cell development. The restricted...

Cytotoxic T lymphocyte antigen-4-dependent down-modulation of costimulatory molecules on dendritic cells in CD4+ CD25+ regulatory T-cell-mediated suppression

Oderup, Cecilia, Cederbom, Lukas, Makowska, Anna, Cilio, Corrado M, Ivars, Fredrik

We have previously demonstrated that CD4+ CD25+ natural regulatory T cells (Treg cells) induce down-modulation of CD80 and CD86 (B7) molecules on dendritic cells (DCs) in vitro. In this report we...

T cells developing in fetal thymus of T-cell receptor α-chain transgenic mice colonize γδ T-cell-specific epithelial niches but lack long-term reconstituting potential

Leandersson, Karin, Jaensson, Elin, Ivars, Fredrik

The γδ T cells generated during mouse fetal development are absolutely dependent on their invariant T-cell receptors (TCRs) for their function. However, there is little information on whether the...

Dystroglycan is selectively cleaved at the parenchymal basement membrane at sites of leukocyte extravasation in experimental autoimmune encephalomyelitis

Agrawal, Smriti, Anderson, Per, Durbeej, Madeleine, Van Rooijen, Nico, Ivars, Fredrik, Opdenakker, Ghislain, ...

The endothelial cell monolayer of cerebral vessels and its basement membrane (BM) are ensheathed by the astrocyte endfeet, the leptomeningeal cells, and their associated parenchymal BM, all of which...

Identification of Human S100A9 as a Novel Target for Treatment of Autoimmune Disease via Binding to Quinoline-3-Carboxamides

Björk, Per, Björk, Anders, Vogl, Thomas, Stenström, Martin, Liberg, David, Olsson, Anders, ...

Despite more than 25 years of research, the molecular targets of quinoline-3-carboxamides have been elusive although these compounds are currently in Phase II and III development for treatment of...