Spurious spatial periodicity of co-expression in microarray data due to printing design
Balázsi, Gábor, Kay, Krin A., Barabási, Albert-László, Oltvai, Zoltán N.
Global transcriptome data is increasingly combined with sophisticated mathematical analyses to extract information about the functional state of a cell. Yet the extent to which the results reflect...
Spurious spatial periodicity of co-expression in microarray data due to printing design
Balázsi, Gábor, Kay, Krin A., Barabási, Albert-László, Oltvai, Zoltán N.
Global transcriptome data is increasingly combined with sophisticated mathematical analyses to extract information about the functional state of a cell. Yet the extent to which the results reflect...
Combinatorial promoter design for engineering noisy gene expression
Murphy, Kevin F., Balázsi, Gábor, Collins, James J.
Understanding the behavior of basic biomolecular components as parts of larger systems is one of the goals of the developing field of synthetic biology. A multidisciplinary approach, involving...
A Semi-Supervised Method for Predicting Transcription Factor–Gene Interactions in Escherichia coli
Ernst, Jason, Beg, Qasim K., Kay, Krin A., Balázsi, Gábor, Oltvai, Zoltán N., Bar-Joseph, Ziv
While Escherichia coli has one of the most comprehensive datasets of experimentally verified transcriptional regulatory interactions of any organism, it is still far from complete. This presents a...
Planktonic copepods reacting selectively to hydrodynamic disturbances
Strickler, J. Rudi, Balázsi, Gábor
In the water column, planktonic copepods encounter small-scale hydrodynamic disturbances generated by fellow zooplankters. Our question is whether or not the copepods can distinguish between...
The temporal response of the Mycobacterium tuberculosis gene regulatory network during growth arrest
Balázsi, Gábor, Heath, Allison P, Shi, Lanbo, Gennaro, Maria L
The virulence of Mycobacterium tuberculosis depends on the ability of the bacilli to switch between replicative (growth) and non-replicative (dormancy) states in response to host immunity. However,...
Nevozhay, Dmitry, Adams, Rhys M., Murphy, Kevin F., Josić, Krešimir, Balázsi, Gábor
Although several recent studies have focused on gene autoregulation, the effects of negative feedback (NF) on gene expression are not fully understood. Our purpose here was to determine how the...