Scientific Commons: G. C. Nicholson

Vitamin D acts through the immature osteoblast to stimulate osteoclastogenesis. Transgenic elevation of VDR in mature osteoblasts was found to inhibit osteoclastogenesis associated with an altered...

Vitamin D action and regulation of bone remodeling: Suppression of osteoclastogenesis by the mature osteoblast (2006)

Baldock, P. A., Thomas, G. P., Hodge, J. M., Baker, S. U. K., Dressel, U., O'Loughlin, P. D., ...

Vitamin D acts through the immature osteoblast to stimulate osteoclastogenesis. Transgenic elevation of VDR in mature osteoblasts was found to inhibit osteoclastogenesis associated with an altered...

Differential activity of human RUNX2 P2 promoter alleles associated with deciles of BMD show an allele-specific DNA-protein interaction in osteoblast nuclear extracts. (2005)

Doecke, James David, Stephens, Alexandre, Nicholson, G.C., Morrison, Nigel Alexander

No

Glutamine repeat mutations define a new RUNX2 related syndrome with decreased femoral neck BMD, decreased calcaneal ultrasound and increased risk of osteoporotic fracture (2005)

Stephens, Alexandre, Doecke, James David, Ralston, S.H., Prince, R., Nicholson, G.C., Morrison, Nigel Alexander

No

Differential activity of human RUNX2 P2 promoter alleles associated with deciles of BMD show an allele-specific DNA-protein interaction in osteoblast nuclear extracts. (2005)

Doecke, James David, Stephens, Alexandre, Nicholson, G.C., Morrison, Nigel Alexander

No

Glutamine repeat mutations define a new RUNX2 related syndrome with decreased femoral neck BMD, decreased calcaneal ultrasound and increased risk of osteoporotic fracture (2005)

Stephens, Alexandre, Doecke, James David, Ralston, S.H., Prince, R., Nicholson, G.C., Morrison, Nigel Alexander

No

Differential activity of human RUNX2 P2 promoter alleles associated with deciles of BMD show an allele-specific DNA-protein interaction in osteoblast nuclear extracts. (2005)

Doecke, James David, Stephens, Alexandre, Nicholson, G.C., Morrison, Nigel Alexander

Glutamine repeat mutations define a new RUNX2 related syndrome with decreased femoral neck BMD, decreased calcaneal ultrasound and increased risk of osteoporotic fracture (2005)

Stephens, Alexandre, Doecke, James David, Ralston, S.H., Prince, R., Nicholson, G.C., Morrison, Nigel Alexander

Differential activity of human RUNX2 P2 promoter alleles associated with deciles of BMD show an allele-specific DNA-protein interaction in osteoblast nuclear extracts. (2005)

Doecke, James David, Stephens, Alexandre, Nicholson, G.C., Morrison, Nigel Alexander

Glutamine repeat mutations define a new RUNX2 related syndrome with decreased femoral neck BMD, decreased calcaneal ultrasound and increased risk of osteoporotic fracture (2005)

Stephens, Alexandre, Doecke, James David, Ralston, S.H., Prince, R., Nicholson, G.C., Morrison, Nigel Alexander

Over-expression of TBP-2, a protein involved in redox regulation, inhibits osteoclastogenesis. (2003)

Aitken, C.J., JM, Hodge, Vaughan, Tanya, DE, Myers, Morrison, Nigel Alexander, Nicholson, G.C.

Using gene array analysis, we found that thioredoxin (TRX) binding protein-2 (TBP-2) was down-regulated during osteoclast (OC) differentiation. TBP-2 is a negative regulator of TRX, a small protein...

Transcription factors involved in osteoclastogenesis. (2003)

Day, Chris, Kim, Michael Soo Ho, Nicholson, G.C., Morrison, Nigel Alexander

Surprisingly, very few transcription factors have been implicated in osteoclast differentiation. Newly discovered upregulated transcription factors are obviously important in understanding osteoclast...

Over-expression of TBP-2, a protein involved in redox regulation, inhibits osteoclastogenesis. (2003)

Aitken, C.J., JM, Hodge, Vaughan, Tanya, DE, Myers, Morrison, Nigel Alexander, Nicholson, G.C.

Using gene array analysis, we found that thioredoxin (TRX) binding protein-2 (TBP-2) was down-regulated during osteoclast (OC) differentiation. TBP-2 is a negative regulator of TRX, a small protein...

Transcription factors involved in osteoclastogenesis. (2003)

Day, Chris, Kim, Michael Soo Ho, Nicholson, G.C., Morrison, Nigel Alexander

Surprisingly, very few transcription factors have been implicated in osteoclast differentiation. Newly discovered upregulated transcription factors are obviously important in understanding osteoclast...

Over-expression of TBP-2, a protein involved in redox regulation, inhibits osteoclastogenesis. (2003)

Aitken, C.J., JM, Hodge, Vaughan, Tanya, DE, Myers, Morrison, Nigel Alexander, Nicholson, G.C.

Using gene array analysis, we found that thioredoxin (TRX) binding protein-2 (TBP-2) was down-regulated during osteoclast (OC) differentiation. TBP-2 is a negative regulator of TRX, a small protein...

Transcription factors involved in osteoclastogenesis. (2003)

Day, Chris, Kim, Michael Soo Ho, Nicholson, G.C., Morrison, Nigel Alexander

Surprisingly, very few transcription factors have been implicated in osteoclast differentiation. Newly discovered upregulated transcription factors are obviously important in understanding osteoclast...

Taq IA and Ser311Cys polymorphisms in the dopamine D2 receptor gene and obesity (2003)

Southon, A., Walder, K., Sanigorski, A. M., Zimmet, P., Nicholson, G. C., Kotowicz, M., ...

Dopamine D2 receptors (DRD2) in the central nervous system are involved in the regulation of feeding. It remains to be elucidated if mutations in the DRD2 gene contribute to the development of...

Over-expression of TBP-2, a protein involved in redox regulation, inhibits osteoclastogenesis. (2003)

Aitken, C.J., JM, Hodge, Vaughan, Tanya, DE, Myers, Morrison, Nigel Alexander, Nicholson, G.C.

Using gene array analysis, we found that thioredoxin (TRX) binding protein-2 (TBP-2) was down-regulated during osteoclast (OC) differentiation. TBP-2 is a negative regulator of TRX, a small protein...

Transcription factors involved in osteoclastogenesis. (2003)

Day, Chris, Kim, Michael Soo Ho, Nicholson, G.C., Morrison, Nigel Alexander

Surprisingly, very few transcription factors have been implicated in osteoclast differentiation. Newly discovered upregulated transcription factors are obviously important in understanding osteoclast...

The taq IA and Ser311Cys polymorphisms in the dopamine D2 receptor gene and obesity (2003)

Southon, A., Walder, K., Sanigorski, A. M., Zimmet, P., Nicholson, G. C., Kotowicz, M., ...

Dopamine D2 receptors (DRD2) in the central nervous system are involved in the regulation of feeding. It remains to be elucidated if mutations in the DRD2 gene contribute to the development of...

The identification of genes regulated in osteoclast differentiation by array analysis. (2002)

Vaughan, Tanya, Aitken, C.J., Leroy, Jethro, Simcock, Wendy Elizabeth, Nicholson, G.C., Morrison, Nigel Alexander

No

The identification of genes regulated in osteoclast differentiation by array analysis. (2002)

Vaughan, Tanya, Aitken, C.J., Leroy, Jethro, Simcock, Wendy Elizabeth, Nicholson, G.C., Morrison, Nigel Alexander

No

The identification of genes regulated in osteoclast differentiation by array analysis. (2002)

Vaughan, Tanya, Aitken, C.J., Leroy, Jethro, Simcock, Wendy Elizabeth, Nicholson, G.C., Morrison, Nigel Alexander

A Randomized Trial of Sodium Fluoride (60 mg) ± Estrogen in Postmenopausal Osteoporotic Vertebral Fractures: Increased Vertebral Fractures and Peripheral Bone Loss with Sodium Fluoride; Concurrent Estrogen Prevents Peripheral Loss, But Not Vertebral Fractures (2002)

Gutteridge, D.H., Stewart, G.O., Prince, R.L., Price, R.I., Retallack, R.W., Dhaliwal, S.S., ...

The original publication can be found at www.springerlink.com

A Randomized Trial of Sodium Fluoride (60 mg) ± Estrogen in Postmenopausal Osteoporotic Vertebral Fractures: Increased Vertebral Fractures and Peripheral Bone Loss with Sodium Fluoride; Concurrent Estrogen Prevents Peripheral Loss, But Not Vertebral Fractures (2002)

Gutteridge, D.H., Stewart, G.O., Prince, R.L., Price, R.I., Retallack, R.W., Dhaliwal, S.S., ...

The original publication can be found at www.springerlink.com

The identification of genes regulated in osteoclast differentiation by array analysis. (2002)

Vaughan, Tanya, Aitken, C.J., Leroy, Jethro, Simcock, Wendy Elizabeth, Nicholson, G.C., Morrison, Nigel Alexander

Genomewide search in familial Paget disease of bone shows evidence of genetic heterogeneity with candidate loci on chromosomes 2q36, 10p13, and 5q35 (2001)

Herbert, C A, Nicholls, R K, Williams, F, Bennett, S T, Cundy, T, ...

Paget disease of bone (PDB) is a common disorder characterized by focal abnormalities of increased and disorganized bone turnover. Genetic factors are important in the pathogenesis of PDB, and...

Abundant calcitonin receptors in isolated rat osteoclasts. Biochemical and autoradiographic characterization.

Nicholson, G C, Moseley, J M, Sexton, P M, Mendelsohn, F A, Martin, T J

Calcitonin receptors have been characterized for the first time in isolated osteoclasts. These receptors have been demonstrated by autoradiographic and biochemical methods, and the cells have also...

Human placental calcitonin receptors.

Nicholson, G C, D'Santos, C S, Evans, T, Moseley, J M, Kemp, B E, Michelangeli, V P, ...

Receptors for the hypocalcaemic hormone, calcitonin (CT), have been identified in a membrane fraction prepared from term human placentae. Binding of 125I-labelled salmon CT (125I-sCT) to the...

Solubilization of functional calcitonin receptors.

Nicholson, G C, D'Santos, C S, Evans, T, Moseley, J M, Kemp, B E, Martin, T J

Calcitonin (CT) binding activity has been extracted from a membrane fraction of human placenta using the zwitterionic detergent, 3-[(3-cholamidopropyl)dimethylammonio]-1-propanesulphonic acid...

Abundant calcitonin receptors in isolated rat osteoclasts. Biochemical and autoradiographic characterization.

Nicholson, G C, Moseley, J M, Sexton, P M, Mendelsohn, F A, Martin, T J

Calcitonin receptors have been characterized for the first time in isolated osteoclasts. These receptors have been demonstrated by autoradiographic and biochemical methods, and the cells have also...

Human placental calcitonin receptors.

Nicholson, G C, D'Santos, C S, Evans, T, Moseley, J M, Kemp, B E, Michelangeli, V P, ...

Receptors for the hypocalcaemic hormone, calcitonin (CT), have been identified in a membrane fraction prepared from term human placentae. Binding of 125I-labelled salmon CT (125I-sCT) to the...

Solubilization of functional calcitonin receptors.

Nicholson, G C, D'Santos, C S, Evans, T, Moseley, J M, Kemp, B E, Martin, T J

Calcitonin (CT) binding activity has been extracted from a membrane fraction of human placenta using the zwitterionic detergent, 3-[(3-cholamidopropyl)dimethylammonio]-1-propanesulphonic acid...

G. C. Nicholson

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