G. Chrebet

Yeast FKBP-13 is a membrane-associated FK506-binding protein encoded by the nonessential gene FKB2.

Nielsen, J B, Foor, F, Siekierka, J J, Hsu, M J, Ramadan, N, Morin, N, ...

The immunosuppressants FK506 and rapamycin prevent T-cell activation and also inhibit the growth of certain strains of the yeast Saccharomyces cerevisiae. It has previously been shown that yeast...

Antifungal properties of the immunosuppressant FK-506: identification of an FK-506-responsive yeast gene distinct from FKB1.

Brizuela, L, Chrebet, G, Bostian, K A, Parent, S A

FK-506 is a novel and potent antagonist of T-cell activation and an inhibitor of fungal growth. Its immunosuppressive activity can be antagonized by the structurally related antibiotic rapamycin, and...

Specific Substitutions in the Echinocandin Target Fks1p Account for Reduced Susceptibility of Rare Laboratory and Clinical Candida sp. Isolates

Park, S., Kelly, R., Kahn, J. Nielsen, Robles, J., Hsu, M.-J., Register, E., ...

An association between reduced susceptibility to echinocandins and changes in the 1,3-β-d-glucan synthase (GS) subunit Fks1p was investigated. Specific mutations in fks1 genes from Saccharomyces...

Yeast FKBP-13 is a membrane-associated FK506-binding protein encoded by the nonessential gene FKB2.

Nielsen, J B, Foor, F, Siekierka, J J, Hsu, M J, Ramadan, N, Morin, N, ...

The immunosuppressants FK506 and rapamycin prevent T-cell activation and also inhibit the growth of certain strains of the yeast Saccharomyces cerevisiae. It has previously been shown that yeast...

Antifungal properties of the immunosuppressant FK-506: identification of an FK-506-responsive yeast gene distinct from FKB1.

Brizuela, L, Chrebet, G, Bostian, K A, Parent, S A

FK-506 is a novel and potent antagonist of T-cell activation and an inhibitor of fungal growth. Its immunosuppressive activity can be antagonized by the structurally related antibiotic rapamycin, and...

Specific Substitutions in the Echinocandin Target Fks1p Account for Reduced Susceptibility of Rare Laboratory and Clinical Candida sp. Isolates

Park, S., Kelly, R., Kahn, J. Nielsen, Robles, J., Hsu, M.-J., Register, E., ...

An association between reduced susceptibility to echinocandins and changes in the 1,3-β-d-glucan synthase (GS) subunit Fks1p was investigated. Specific mutations in fks1 genes from Saccharomyces...